Achmad Fauzi Kamal
Departmen Orthopaedi Dan Traumatologi Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo/Fakultas Kedokteran Universitas Indonesia,Jakarta

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Pengaruh Autoclave terhadap Properti Fisik dan Histopatologi Tulang: Sebuah Penelitian Dasar Rekonstruksi WIRATNAYA, I GEDE EKA; KAMAL, ACHMAD FAUZI; PATTIATA, RINO
Indonesian Journal of Cancer Vol 8, No 1 (2014): Jan - Mar 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Background: Autoclave autograft is a promising alternative procedure in surgical treatment of bone tumors. A minimum effective autoclaving time of 15 minutes at 134°C to devitalise tumour cells. This study aims to know the effect of autoclave to physical properties and histopathology of bone.Methods: We performed experimental study in 28 femoral bone of goat (Capra Aergagus circus) at age 1?2 year old. We divide into two groups with simple random sampling to be 14 autoclave and 14 control group. Autoclaving was performed to the bone at 134°C for 15 minute. We examined physical properties each 7 autoclave group to axial and bending force compared with physical properties of the control group. We also examined histopatology of the bone both groups. Independent t-test statistical analysis to evaluate the difference of axial and bending force between autoclave and control group.Results: There were significant difference between autoclave and control group in axial force (p = 0.000) and bending force (p = 0.03). Physical properties of autoclave bone decreased 58.58 % in axial force and 20.33% bending force to control group. Histopathology examination revealed that all osteocytes were death in autoclave group but without matrix changes.Conclusion: Autoclave at 134°C for 15 minute caused physical properties of bone decrease and statistically significant difference. It also made all osteocytes died but without matrix disturbance.
A Modified Buttockectomy as a Limb Salvage Procedure in Ischium Osteosarcoma: A Case Report KAMAL, ACHMAD FAUZI; DJAJA, YOSHI PRATAMA; KODRAT, EVELINA; SALAMAH, THARIQAH
Indonesian Journal of Cancer Vol 9, No 2 (2015): April-Juni 2015
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Osteosarcoma, which rarely originates from the axial bones such as pelvis, presents a major challenge in limb preservation. We report a 9-year-old girl with osteosarcoma on her buttock. She underwent wide excision “modified buttockectomy” to resect the tumour with sciatic nerve involvement. One year after surgery, she was able to walk and no recurrence was found. Keywords: buttockectomy, osteosarcoma ABSTRAKOsteosarkoma, tulang aksial seperti pelvis jarang sekali ditemukan, dan menjadi tantangan besar dalam upaya penyelamatan ekstremitas. Kami laporkan satu kasus osteosarkoma pada tulang panggul-daearah bokong pada seorang anak perempuan berusia 9 tahun. Pasien menjalani eksisi luas “buttockectomy” yang dimodifikasi untuk mengangkat tumor beserta nervus ischiadikus yang terlibat. Pada pengamatan satu tahun pasca pembedahan, pasien dapat berjalan dan tidak ditemukan tanda-tanda rekurensi. Kata Kunci: buttockectomy, osteosarkoma
Sacral Tumor: Experience in a Single Institution KAMAL, ACHMAD FAUZI
Indonesian Journal of Cancer Vol 9, No 1 (2015): Jan - Mar 2015
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

ABSTRACTIntroduction. Sacral tumors are rare, and experience of these tumors is usually limited to a small number of patients. Inthis study, we evaluated profile, survival rates, and functional outcome in a series of sacral tumor treated in our institution.Method. We retrospectively reviewed the records of 22 sacral tumor patients from January 1995 to February 2014 inCipto Mangunkusumo National Central Hospital, Jakarta, Indonesia. Kaplan-Meier method was used to describedsurvival and functional outcome. Their correlation with clinical profile, histological type, level of sacral involvement,treatment, and complication were analyzed by Log rank test.Results. From 22 patients, 5 of them were excluded from this study. Thus, there were 17 cases of sacral tumor, 16 ofthem were malignant and one case was benign. In Kaplan-Meier Analysis, there were no significant difference insurvival found between sex, age group, biopsy type, level of sacral involvement, treatment, and complication. There wassignificant difference in survival found between histopathology result (p=0.012), and giant cell tumor GCT showed thehighest survival, followed by chordoma, metastatic lession, and Ewing Sarcoma. Sacral tumor at the level of S2 andbelow had better functional outcome compared to the one above S2 (p=0.001). There were no difference in functionaloutcome found between histopathology type and treatment (p=0.137 and p=0.210).Conclusion. The majority of primary tumors of sacrum are chordoma which present with nonspecific early signs andsymptoms. Survival rate and functional outcome of the sacral tumor patients were determined by histopathology resultand level of sacral involvement. Lower level of sacral involvement lead to better survival and functional outcome.Keyword: sacral tumors, chordoma, giant-cell tumor, metastasis, survival, functional outcomeABSTRAKPendahuluan. Tumor sakrum sangat jarang ditemukan; dan pengalaman mengenai tumor sakrum biasanya terbataspada sejumlah kecil pasien. Dalam studi ini, kami mengevaluasi profil, tingkat kesintasan, dan luaran fungsional dariserangkaian tumor sakrum yang dirawat di institusi kami.Metode. Kami telah mengevaluasi 22 pasien tumor sakrum dari Januari 1995 sampai Februari 2014 secara retrospektif diRumah Sakit Umum Pusat Nasional Cipto Mangunkusumo Jakarta Indonesia. Metode Kaplan-Meier digunakan untukmenganalisis angka kesintasan dan luaran fungsional. Hubungan antara kesintasan dan luaran fungsional dengan profilklinis, jenis histopatologi, level sakrum yang terlibat, penatalaksanaan, dan komplikasi dianalisis dengan Log rank test.Hasil. Dari 22 pasien, hanya 17 pasien tumor sakrum yang dimasukkan ke dalam studi ini (5 kasus diekslusi), 16 kasusdengan tumor ganas dan 1 kasus dengan tumor jinak. Hasil analisis Kaplan-Meier menunjukkan tidak ada perbedaanyang bermakna pada angka kesintasan terhadap jenis kelamin, kelompok umur, jenis biopsi, level sakrum yang terlibat,penatalaksanaan, dan komplikasi. Hasil uji statististik menunjukkan perbedaan yang bermakna antara kesintasandengan hasil histopatologi (p = 0,012), giant cell tumor menunjukkan kesintasan hidup tertinggi, diikuti oleh Chordoma,lesi metastasis, dan Ewing Sarcoma. Tumor sakrum setinggi S2 ke bawah memiliki luaran fungsional yang lebih baikdibandingkan dengan level di atas S2 (p = 0,001). Hasil uji statistik menunjukkan tidak ada perbedaan yang bermakna antara luaran fungsional dengan jenis histopatologi dan penatalaksanaan(p = 0,137 dan p = 0,210). Kesimpulan. Mayoritas tumor primer pada tulang sakrum adalah chordoma yang muncul dengan gejala dan tanda-tanda awal yang tidak spesifik. Angka kesintasan dan luaran funsional pasien tumor sakrum dipengaruhi oleh jenis histopatologi dan level sacrum yang terlibat. Semakin rendah level sacrum yang terlibat, semakin baik kesintasan dan luaran fungsional.Kata Kunci: Tumor sakrum, Chordoma, giant cell tumor, metastasis,kesintasan, luaran fungsional
Schwannoma Nervus Ulnaris KAMAL, ACHMAD FAUZI; MASKA, HENDRA
Indonesian Journal of Cancer Vol 9, No 3 (2015): Jul - Sept 2015
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Ulnar nerve schwannoma is a rare peripheral nerve tumor. Accurate preoperative diagnosis is very important to evaluate the involvement of certain peripheral nerve and surgical planning. MRI is very important investigation for diagnosis before surgery. Surgical management principle in this case is to remove the tumor mass and preserve main ulnar nerve. Schwannoma nervus ulnaris merupakan tumor saraf tepi yang jarang ditemukan. Diagnosis yang akurat sebelum pembedahan sangat penting untuk menilai keterlibatan saraf tepi tertentu dan merencanakan tindakan pembedahan. MRI merupakan pemeriksaan penunjang yang sangat bermanfaat untuk menegakkan diagnosis sebelum pembedahan. Prinsip penatalaksanaan bedah pada kasus ini adalah mengangkat massa tumor dan mempertahankan serabut utama nervus ulnaris.
Simple Bone Cyst Management: Percutaneous Steroid Injection Versus Curettage With Hydroxiapatite KAMAL, ACHMAD FAUZI; APRIZAL, RIZA; PRABOWO, YOGI
Indonesian Journal of Cancer Vol 11, No 2 (2017): April - June
Publisher : Indonesian Journal of Cancer

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ABSTRACT The main goals of the therapy of simple bone cyst (SBC) are to get the bone healing, prevent pathological fractures, and management of pain symptom. There are various methods of the SBC treatments, however they still remain controversial because of their healing rate and invasiveness of surgery. A total of 10 SBC patients were divided into two groups namely curretage with hydroxyapatite (HA) and decompression and percutaneous steroid injection (PSI). PSI was performed three times at intervals of each month. The mean followup of 12-26 months. Evaluation of functional outcome by Musculoskeletal Tumour Society (MSTS) score and supported with radiologically based on Chang criteria. There were 5 patients (proximal femur 2; proximal humerus 2, radius 1) performed curretage with HA therapy. Remaining 5 patients (proximal femur 3; proximal humerus 1; calcaneus 1) were performed PSI therapy. PSI group had better MSTS score, particulary at month 3 (55%) and month 6 (84%) than curettage with HA therapy (47% and 69.3%). Complete bone healing was found in both group at month 12 follow up, however solid union occurred faster in PSI group. PSI tends to have faster and better functional outcome than curettage and HA. Curettage with HA and PSI have similar complete bone healing at month 12 follow up. ABSTRAKTarget utama penalaksanaan simple bone cyst (SBC) adalah mencapat penyembuhan tulang yang sempurna, mencegah fraktur patologis dan mengatasi gejala nyeri. Ada beberapa metode penatalaksanaan SBC, namun demikian masih menjadi perdebatan dikarenakan perbedaan angka penyembuhannya dan jenis pembedahan yang invsif. Sepuluh pasien yang didiagnosis SBC dikelompokkan menjadi kelompok yang mendapat tindakan curretage dan pengisian defek dengan hydroxyapatite (HA) dan kelompok dekompresi dan percutaneous steroid injection (PSI). Prosedur PSIdilakukan sebanyak 3x dengan interval waktu satu bulan. Follow up dilakukan selama 12 – 26 bulan. Evaluasi luaran fungsional menggunakan Musculoskeletal Tumour Society (MSTS) score dan secara radiologi sesuai criteria Chang. Terdapat 5 pasien (2 femur proksimal, 2 humerus proksimal, dan 1 radius) yang dilakukan prosedur curretage dan pengisian defek dengan HA. Lima pasien sisanya ( 3 fenur proximal, 1 humerus proximal dan 1 calcaneus) dilakukan prosedur PSI. Luaran fungsional Kelompok PSI memiliki MSTS score yang lebih baik, khususnya pada bulan ke- 3 (55%) dan bulan ke-6 (84%) daripada kelompok curettage dengan HA (47% dan 69.3%). Penyembulan tulang sempurna menunjukkan hasil yang sama pada evaluasi bulan ke-12, tetapi solid union didapatkan lebih cepat pada kelompok PSI. Kelompok PSI memiliki kecenderungan solid union dan luaran fungsional yang lebih cepat daripada kelompok curettage dengan HA. Kedua kelompok mencapai penyembuhan sempurna pada bulan ke-12 follow up
Pengaruh Autoclave terhadap Properti Fisik dan Histopatologi Tulang: Sebuah Penelitian Dasar Rekonstruksi WIRATNAYA, I GEDE EKA; KAMAL, ACHMAD FAUZI; PATTIATA, RINO
Indonesian Journal of Cancer Vol 8, No 1 (2014): Jan - Mar 2014
Publisher : Indonesian Journal of Cancer

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.906 KB)

Abstract

Background: Autoclave autograft is a promising alternative procedure in surgical treatment of bone tumors. A minimum effective autoclaving time of 15 minutes at 134C to devitalise tumour cells. This study aims to know the effect of autoclave to physical properties and histopathology of bone.Methods: We performed experimental study in 28 femoral bone of goat (Capra Aergagus circus) at age 1?2 year old. We divide into two groups with simple random sampling to be 14 autoclave and 14 control group. Autoclaving was performed to the bone at 134C for 15 minute. We examined physical properties each 7 autoclave group to axial and bending force compared with physical properties of the control group. We also examined histopatology of the bone both groups. Independent t-test statistical analysis to evaluate the difference of axial and bending force between autoclave and control group.Results: There were significant difference between autoclave and control group in axial force (p = 0.000) and bending force (p = 0.03). Physical properties of autoclave bone decreased 58.58 % in axial force and 20.33% bending force to control group. Histopathology examination revealed that all osteocytes were death in autoclave group but without matrix changes.Conclusion: Autoclave at 134C for 15 minute caused physical properties of bone decrease and statistically significant difference. It also made all osteocytes died but without matrix disturbance.
The Effectiveness of Psychoreligious Intervention: Murottal Al-Quran on Pain and Stress Level of Bone Cancer Patient Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia
Indonesian Journal of Global Health Research Vol 2 No 4 (2020): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.466 KB) | DOI: 10.37287/ijghr.v2i4.260

Abstract

Psychoreligious intervention of murottal Al-Qur'an is a therapy given to patients by listening to verses of the Qur'an for a few minutes to have a positive impact on the patient's physiological and psychological condition, thereby providing a relaxing effect to reduce pain and stress level. The purpose of this study was to determine the effectiveness of psychoreligious intervention of murrotal Al-Quran on pain and stress level of bone cancer patients in Semarang Regency. This was a quasi-experimental study with pre and post-test through a control group design. The population of this study were patients with bone cancer who were undergoing outpatient care in Semarang Regency Hospital, living in the regency of Semarang. The sampling technique used was purposive sampling with the number of respondents obtained 36 patients. The data were collected through Numeric Rating Scale aiming to measure the pain scale and DASS 42 questionnaire consisting of 14 statements to measure the level of stress. The therapeutic action procedure of psychoreligious intervention of murrotal Al-Quran used Ar-Rahman letter for 20 minutes which was in accordance with standard operating procedures. The data were analyzed using t-test. The results showed that there was a significant difference of pain and stress level before and after the intervention. Psychoreligious intervention of murottal Al-Qur'an was effective in reducing pain level in bone cancer patients (p-value=0.001<α=0.05). Psychoreligious intervention of murottal Al-Qur'an can effectively reduce stress level of bone cancer patients (p-value=0.001<α=0.05). Psychoreligious intervention of murrotal Al-Quran can be used as a therapeutic modality to reduce the pain and stress level of bone cancer patients during home treatment period which brings positive impact to improve the patient's physiological and psychological well-being. This intervention will help the process of recovery of the patients from their cancer.
Integrated Nursing Intervention Theory in Providing Comfortableness to Increase Patient Well Being: Simple Theory Construction Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia; Saptawati Bardosono
Indonesian Journal of Global Health Research Vol 3 No 4 (2021): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (601.488 KB) | DOI: 10.37287/ijghr.v3i4.720

Abstract

This article shows that an integrated and compatible independent nursing intervention model approach is important to be able to hope of providing a strong theoretical basis for nurses on improving the wellbeing of acute coronary syndrome patients through a conceptual model of integrated nursing interventions during treatment in the hospital. The purpose of this article is to present a simple theoretical construction using a 7-step approach which includes: origin, meaning, logical adequacy, usefulness, generaliability and parsimony as well as testability, about integrative nursing intervention theory in providing comfort to improve patient well being. This type of research is a development research model with a simple theory construction model approach. The problems faced by patients with acute coronary syndrome most often are chest pain, anxiety and hemodynamics which can interfere the patient's well-being. Chest pain that is occurred due to coronary blockage has an impact on the fear of death and can affect hemodynamic stability. Anxiety is the most prominent stress and greatly disturbs the patient's psychological condition. The integrative nursing intervention model becomes a model approach that can be applied by nurses in nursing care services for patients with acute coronary syndrome. Therefore, the role of nurses as service providers should be able to make the best contribution through the application of an integrative nursing intervention model. This intervention model approach is expected to be able to improve patient well being during hospitalization.
Measurements of Patellofemoral Morphology Characteristics in Indonesian Population: an MRI Based Study Ludwig Andre Pontoh; Ismail Hadisoebroto Dilogo; Achmad Fauzi Kamal; Wahyu Widodo; Sholahuddin Rhatomy; Jessica Fiolin
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v15i2.3043

Abstract

Patellar malalignment is the imbalance relationship between patella and trochlea, in which clinical findings most of the time are obscured; hence diagnosis is often challenging. Magnetic resonance imaging (MRI) is the most sensitive tool to detect subtle patellar malalignment features, so diagnosis can be made early. However, there has been no clear consensus on the normal value of patella morphology until today. This study aims to determine patellofemoral morphology values in Indonesian using MRI. This was a retrospective study of 202 patients aged 18-40 years old with knee problems without patellar instability. Patellar morphology parameters including Insal Savati ratio (IS ratio), patellar tilt angle (PTA), sulcus angle (SA) and tibial tubercle-trochlear groove distance    (TT-TG) were evaluated and recorded for statistical analysis. There was no significant correlation between anthropometric values and patellar morphology values. There were significantly higher PTA, SA and TT-TG values in females compared to males. The mean value of the IS ratio in the Asian population using MRI was 0.99 ± 0.14, PTA was 9.09 ± 6.88, SA was 139.20 ± 6.38, and TT-TG distance was 8.00 ± 5.25. Further studies with larger samples and multi-center results are required.
The Effectiveness of Psychoreligious Therapy: Murottal Al Qur'an on Chest Pain Level of the Patient in Intensive Care Unit Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia; Idia Indar Anggraeni
Proceedings of the International Conference on Nursing and Health Sciences Vol 1 No 1 (2020): November 2020
Publisher : Global Health Science Group

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Abstract

Chest pain is the main complaint felt by patients with coronary heart disease. Chest pain occurs during a heart attack when oxygen supply to the myocardium is decreased. Psychoreligious therapy: murottal Al-Qur'an is a psychoreligious therapy given to patients by listening to verses of the Qur'an for a few minutes to have a positive impact on the patient's psychological condition, thereby providing a relaxing effect to reduce pain. This study aims to determine the effectiveness of psychoreligious therapy: murottal Al-Qur'an on the level of chest pain. This research design used pre-experimental method with one group pre and post-test design. The population of this study were patients with coronary syndrome acute who were treated in the Intensive Care Unit of the Tidar General Hospital Magelang. The sampling technique used accidental sampling, with a total of 34 respondents. The research instrument used the Numeric Rating Scale to measure the scale of chest pain before and after therapy. Psychoreligious therapy: murottal Al-Qur'an given according to standard operating procedures for 20 minutes. The statistical test used paired t test. The results showed that there was a significant difference from chest pain level before and after psychoreligious therapy: murottal Al-Qur'an with p-value 0.000 (p<α (0.05)). Psychoreligious therapy: murottal Al-Qur'an can effectively reduce the scale of the patient's chest pain. There is a need for socialization and application of psychoreligious therapy: murottal Al-Qur'an as a therapeutic modality and further research is needed on various psychoreligious therapies that are useful in nursing care services in hospitals.