Achmad Fauzi Kamal
Departmen Orthopaedi Dan Traumatologi Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo/Fakultas Kedokteran Universitas Indonesia,Jakarta

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Pengaruh Autoclave terhadap Properti Fisik dan Histopatologi Tulang: Sebuah Penelitian Dasar Rekonstruksi I GEDE EKA WIRATNAYA; ACHMAD FAUZI KAMAL; RINO PATTIATA
Indonesian Journal of Cancer Vol 8, No 1 (2014): Jan - Mar 2014
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.906 KB) | DOI: 10.33371/ijoc.v8i1.285

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Background: Autoclave autograft is a promising alternative procedure in surgical treatment of bone tumors. A minimum effective autoclaving time of 15 minutes at 134C to devitalise tumour cells. This study aims to know the effect of autoclave to physical properties and histopathology of bone.Methods: We performed experimental study in 28 femoral bone of goat (Capra Aergagus circus) at age 1?2 year old. We divide into two groups with simple random sampling to be 14 autoclave and 14 control group. Autoclaving was performed to the bone at 134C for 15 minute. We examined physical properties each 7 autoclave group to axial and bending force compared with physical properties of the control group. We also examined histopatology of the bone both groups. Independent t-test statistical analysis to evaluate the difference of axial and bending force between autoclave and control group.Results: There were significant difference between autoclave and control group in axial force (p = 0.000) and bending force (p = 0.03). Physical properties of autoclave bone decreased 58.58 % in axial force and 20.33% bending force to control group. Histopathology examination revealed that all osteocytes were death in autoclave group but without matrix changes.Conclusion: Autoclave at 134C for 15 minute caused physical properties of bone decrease and statistically significant difference. It also made all osteocytes died but without matrix disturbance.
Sacral Tumor: Experience in a Single Institution ACHMAD FAUZI KAMAL
Indonesian Journal of Cancer Vol 9, No 1 (2015): Jan - Mar 2015
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (653.449 KB) | DOI: 10.33371/ijoc.v9i1.369

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ABSTRACTIntroduction. Sacral tumors are rare, and experience of these tumors is usually limited to a small number of patients. Inthis study, we evaluated profile, survival rates, and functional outcome in a series of sacral tumor treated in our institution.Method. We retrospectively reviewed the records of 22 sacral tumor patients from January 1995 to February 2014 inCipto Mangunkusumo National Central Hospital, Jakarta, Indonesia. Kaplan-Meier method was used to describedsurvival and functional outcome. Their correlation with clinical profile, histological type, level of sacral involvement,treatment, and complication were analyzed by Log rank test.Results. From 22 patients, 5 of them were excluded from this study. Thus, there were 17 cases of sacral tumor, 16 ofthem were malignant and one case was benign. In Kaplan-Meier Analysis, there were no significant difference insurvival found between sex, age group, biopsy type, level of sacral involvement, treatment, and complication. There wassignificant difference in survival found between histopathology result (p=0.012), and giant cell tumor GCT showed thehighest survival, followed by chordoma, metastatic lession, and Ewing Sarcoma. Sacral tumor at the level of S2 andbelow had better functional outcome compared to the one above S2 (p=0.001). There were no difference in functionaloutcome found between histopathology type and treatment (p=0.137 and p=0.210).Conclusion. The majority of primary tumors of sacrum are chordoma which present with nonspecific early signs andsymptoms. Survival rate and functional outcome of the sacral tumor patients were determined by histopathology resultand level of sacral involvement. Lower level of sacral involvement lead to better survival and functional outcome.Keyword: sacral tumors, chordoma, giant-cell tumor, metastasis, survival, functional outcomeABSTRAKPendahuluan. Tumor sakrum sangat jarang ditemukan; dan pengalaman mengenai tumor sakrum biasanya terbataspada sejumlah kecil pasien. Dalam studi ini, kami mengevaluasi profil, tingkat kesintasan, dan luaran fungsional dariserangkaian tumor sakrum yang dirawat di institusi kami.Metode. Kami telah mengevaluasi 22 pasien tumor sakrum dari Januari 1995 sampai Februari 2014 secara retrospektif diRumah Sakit Umum Pusat Nasional Cipto Mangunkusumo Jakarta Indonesia. Metode Kaplan-Meier digunakan untukmenganalisis angka kesintasan dan luaran fungsional. Hubungan antara kesintasan dan luaran fungsional dengan profilklinis, jenis histopatologi, level sakrum yang terlibat, penatalaksanaan, dan komplikasi dianalisis dengan Log rank test.Hasil. Dari 22 pasien, hanya 17 pasien tumor sakrum yang dimasukkan ke dalam studi ini (5 kasus diekslusi), 16 kasusdengan tumor ganas dan 1 kasus dengan tumor jinak. Hasil analisis Kaplan-Meier menunjukkan tidak ada perbedaanyang bermakna pada angka kesintasan terhadap jenis kelamin, kelompok umur, jenis biopsi, level sakrum yang terlibat,penatalaksanaan, dan komplikasi. Hasil uji statististik menunjukkan perbedaan yang bermakna antara kesintasandengan hasil histopatologi (p = 0,012), giant cell tumor menunjukkan kesintasan hidup tertinggi, diikuti oleh Chordoma,lesi metastasis, dan Ewing Sarcoma. Tumor sakrum setinggi S2 ke bawah memiliki luaran fungsional yang lebih baikdibandingkan dengan level di atas S2 (p = 0,001). Hasil uji statistik menunjukkan tidak ada perbedaan yang bermakna antara luaran fungsional dengan jenis histopatologi dan penatalaksanaan(p = 0,137 dan p = 0,210). Kesimpulan. Mayoritas tumor primer pada tulang sakrum adalah chordoma yang muncul dengan gejala dan tanda-tanda awal yang tidak spesifik. Angka kesintasan dan luaran funsional pasien tumor sakrum dipengaruhi oleh jenis histopatologi dan level sacrum yang terlibat. Semakin rendah level sacrum yang terlibat, semakin baik kesintasan dan luaran fungsional.Kata Kunci: Tumor sakrum, Chordoma, giant cell tumor, metastasis,kesintasan, luaran fungsional
Simple Bone Cyst Management: Percutaneous Steroid Injection Versus Curettage With Hydroxiapatite ACHMAD FAUZI KAMAL; RIZA APRIZAL; YOGI PRABOWO
Indonesian Journal of Cancer Vol 11, No 2 (2017): April - June
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1210.015 KB) | DOI: 10.33371/ijoc.v11i2.504

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ABSTRACT The main goals of the therapy of simple bone cyst (SBC) are to get the bone healing, prevent pathological fractures, and management of pain symptom. There are various methods of the SBC treatments, however they still remain controversial because of their healing rate and invasiveness of surgery. A total of 10 SBC patients were divided into two groups namely curretage with hydroxyapatite (HA) and decompression and percutaneous steroid injection (PSI). PSI was performed three times at intervals of each month. The mean followup of 12-26 months. Evaluation of functional outcome by Musculoskeletal Tumour Society (MSTS) score and supported with radiologically based on Chang criteria. There were 5 patients (proximal femur 2; proximal humerus 2, radius 1) performed curretage with HA therapy. Remaining 5 patients (proximal femur 3; proximal humerus 1; calcaneus 1) were performed PSI therapy. PSI group had better MSTS score, particulary at month 3 (55%) and month 6 (84%) than curettage with HA therapy (47% and 69.3%). Complete bone healing was found in both group at month 12 follow up, however solid union occurred faster in PSI group. PSI tends to have faster and better functional outcome than curettage and HA. Curettage with HA and PSI have similar complete bone healing at month 12 follow up. ABSTRAKTarget utama penalaksanaan simple bone cyst (SBC) adalah mencapat penyembuhan tulang yang sempurna, mencegah fraktur patologis dan mengatasi gejala nyeri. Ada beberapa metode penatalaksanaan SBC, namun demikian masih menjadi perdebatan dikarenakan perbedaan angka penyembuhannya dan jenis pembedahan yang invsif. Sepuluh pasien yang didiagnosis SBC dikelompokkan menjadi kelompok yang mendapat tindakan curretage dan pengisian defek dengan hydroxyapatite (HA) dan kelompok dekompresi dan percutaneous steroid injection (PSI). Prosedur PSIdilakukan sebanyak 3x dengan interval waktu satu bulan. Follow up dilakukan selama 12 – 26 bulan. Evaluasi luaran fungsional menggunakan Musculoskeletal Tumour Society (MSTS) score dan secara radiologi sesuai criteria Chang. Terdapat 5 pasien (2 femur proksimal, 2 humerus proksimal, dan 1 radius) yang dilakukan prosedur curretage dan pengisian defek dengan HA. Lima pasien sisanya ( 3 fenur proximal, 1 humerus proximal dan 1 calcaneus) dilakukan prosedur PSI. Luaran fungsional Kelompok PSI memiliki MSTS score yang lebih baik, khususnya pada bulan ke- 3 (55%) dan bulan ke-6 (84%) daripada kelompok curettage dengan HA (47% dan 69.3%). Penyembulan tulang sempurna menunjukkan hasil yang sama pada evaluasi bulan ke-12, tetapi solid union didapatkan lebih cepat pada kelompok PSI. Kelompok PSI memiliki kecenderungan solid union dan luaran fungsional yang lebih cepat daripada kelompok curettage dengan HA. Kedua kelompok mencapai penyembuhan sempurna pada bulan ke-12 follow up
The Effectiveness of Psychoreligious Therapy: Murottal Al Qur'an on Chest Pain Level of the Patient in Intensive Care Unit Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia; Idia Indar Anggraeni
Proceedings of the International Conference on Nursing and Health Sciences Vol 1 No 1 (2020): July-December 2020
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chest pain is the main complaint felt by patients with coronary heart disease. Chest pain occurs during a heart attack when oxygen supply to the myocardium is decreased. Psychoreligious therapy: murottal Al-Qur'an is a psychoreligious therapy given to patients by listening to verses of the Qur'an for a few minutes to have a positive impact on the patient's psychological condition, thereby providing a relaxing effect to reduce pain. This study aims to determine the effectiveness of psychoreligious therapy: murottal Al-Qur'an on the level of chest pain. This research design used pre-experimental method with one group pre and post-test design. The population of this study were patients with coronary syndrome acute who were treated in the Intensive Care Unit of the Tidar General Hospital Magelang. The sampling technique used accidental sampling, with a total of 34 respondents. The research instrument used the Numeric Rating Scale to measure the scale of chest pain before and after therapy. Psychoreligious therapy: murottal Al-Qur'an given according to standard operating procedures for 20 minutes. The statistical test used paired t test. The results showed that there was a significant difference from chest pain level before and after psychoreligious therapy: murottal Al-Qur'an with p-value 0.000 (p<α (0.05)). Psychoreligious therapy: murottal Al-Qur'an can effectively reduce the scale of the patient's chest pain. There is a need for socialization and application of psychoreligious therapy: murottal Al-Qur'an as a therapeutic modality and further research is needed on various psychoreligious therapies that are useful in nursing care services in hospitals.
The Effectiveness of Psychoreligious Intervention: Murottal Al-Quran on Pain and Stress Level of Bone Cancer Patient Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia
Indonesian Journal of Global Health Research Vol 2 No 4 (2020): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.466 KB) | DOI: 10.37287/ijghr.v2i4.260

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Psychoreligious intervention of murottal Al-Qur'an is a therapy given to patients by listening to verses of the Qur'an for a few minutes to have a positive impact on the patient's physiological and psychological condition, thereby providing a relaxing effect to reduce pain and stress level. The purpose of this study was to determine the effectiveness of psychoreligious intervention of murrotal Al-Quran on pain and stress level of bone cancer patients in Semarang Regency. This was a quasi-experimental study with pre and post-test through a control group design. The population of this study were patients with bone cancer who were undergoing outpatient care in Semarang Regency Hospital, living in the regency of Semarang. The sampling technique used was purposive sampling with the number of respondents obtained 36 patients. The data were collected through Numeric Rating Scale aiming to measure the pain scale and DASS 42 questionnaire consisting of 14 statements to measure the level of stress. The therapeutic action procedure of psychoreligious intervention of murrotal Al-Quran used Ar-Rahman letter for 20 minutes which was in accordance with standard operating procedures. The data were analyzed using t-test. The results showed that there was a significant difference of pain and stress level before and after the intervention. Psychoreligious intervention of murottal Al-Qur'an was effective in reducing pain level in bone cancer patients (p-value=0.001<α=0.05). Psychoreligious intervention of murottal Al-Qur'an can effectively reduce stress level of bone cancer patients (p-value=0.001<α=0.05). Psychoreligious intervention of murrotal Al-Quran can be used as a therapeutic modality to reduce the pain and stress level of bone cancer patients during home treatment period which brings positive impact to improve the patient's physiological and psychological well-being. This intervention will help the process of recovery of the patients from their cancer.
Integrated Nursing Intervention Theory in Providing Comfortableness to Increase Patient Well Being: Simple Theory Construction Priyanto Priyanto; Achmad Fauzi Kamal; Debie Dahlia; Saptawati Bardosono
Indonesian Journal of Global Health Research Vol 3 No 4 (2021): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (601.488 KB) | DOI: 10.37287/ijghr.v3i4.720

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This article shows that an integrated and compatible independent nursing intervention model approach is important to be able to hope of providing a strong theoretical basis for nurses on improving the wellbeing of acute coronary syndrome patients through a conceptual model of integrated nursing interventions during treatment in the hospital. The purpose of this article is to present a simple theoretical construction using a 7-step approach which includes: origin, meaning, logical adequacy, usefulness, generaliability and parsimony as well as testability, about integrative nursing intervention theory in providing comfort to improve patient well being. This type of research is a development research model with a simple theory construction model approach. The problems faced by patients with acute coronary syndrome most often are chest pain, anxiety and hemodynamics which can interfere the patient's well-being. Chest pain that is occurred due to coronary blockage has an impact on the fear of death and can affect hemodynamic stability. Anxiety is the most prominent stress and greatly disturbs the patient's psychological condition. The integrative nursing intervention model becomes a model approach that can be applied by nurses in nursing care services for patients with acute coronary syndrome. Therefore, the role of nurses as service providers should be able to make the best contribution through the application of an integrative nursing intervention model. This intervention model approach is expected to be able to improve patient well being during hospitalization.
Terapi Spiritual Doa Tafakur terhadap Peningkatan Kesejahteraan Pasien Kanker: A Systematic Review : Spiritual Therapy of Tafakur Prayer to Increase the Well-Being of Cancer Patients: A Systematic Review Priyanto; Achmad Fauzi Kamal; Debie Dahlia; Besral Besral
Journal of Holistics and Health Sciences (JHHS) Vol. 5 No. 2 (2023): Journal of Holistics and Health Sciences (JHHS), September
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/jhhs.v5i2.341

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Medical surgical nursing care is the main source of service in an effort to achieve quality improvement in the well-being of  cancer patients in hospitals. The well-being of  cancer patients can be improved through various nursing interventions, including spiritual therapy of tafakur prayer. This research is to synthesize the study of spiritual therapy of tafakur prayer on improving the well-being of  cancer patients. This study uses a systematic review approach with quantitative methods using the PRISMA model. The dependent variable is the patient's well-being, and spiritual therapy of tafakur prayer is the independent variable. Of the 323 selected articles, 6 articles met the selected inclusion and exclusion criteria. The articles were collected from 4 database sources namely: EBSCO host, proQuest, Science Direct and Google Scholar. The results of the research show that spiritual therapy of tafakur prayer can improve the quality of life and increase physical well-being, including reducing pain and blood pressure and improving respiratory rate. In addition, spiritual therapy of tafakur prayer can improve psychological and emotional well-being including stress and anxiety as well as spiritual well-being so that it can improve the social well-being of  cancer patients. Spiritual therapy of tafakur prayer can be applied by nurses in medical surgical nursing services for cancer patients in hospitals.   ABSTRAK Asuhan keperawatan medikal bedah menjadi sumber utama pelayanan dalam upaya mencapai kualitas peningkatan kesejahteraan pasien kanker  di rumah sakit. Kesejahteraan pasien kanker  dapat ditingkatkan melalui berbagai intervensi keperawatan, termasuk terapi spiritual doa tafakur. Penelitian ini  untuk mensintesis kajian terapi spiritual doa tafakur terhadap peningkatan kesejahteraan pasien kanker. Penelitian ini menggunakan pendekatan systematic review dengan metode kuantitatif menggunakan model PRISMA. Variabel dependen adalah kesejahteraan pasien, dan terapi spiritual doa tafakur sebagai variabel independen. Dari 323 artikel terseleksi ada 6 artikel yang memenuhi kriteria inklusi dan eksklusi yang dipilih. Artikel-artikel tersebut dikumpulkan dari 4 sumber basis data yaitu: EBSCO host, ProQuest, Science Direct dan Google Scholar. Hasil penelitian menunjukkan bahwa terapi spiritual doa tafakur dapat memperbaiki kualitas hidup dan meningkatkan kesejahteraan fisik, termasuk menurunkan nyeri dan tekanan darah serta memperbaiki laju pernapasan. Selain itu terapi spiritual doa tafakur dapat meningkatkan kesejahteraan psikologis dan emosional termasuk stres dan kecemasan serta kesejahteraan spiritual hingga dapat meningkatkan kesejahteraan sosial pasien kanker. Terapi spiritual doa tafakur dapat diterapkan oleh perawat dalam pelayanan keperawatan medikal bedah pada pasien kanker di rumah sakit.
Perceptions and Experiences of Continuity of Care (COC) Nurses in Lower Limb Fracture Patients: Phenomenological Approach Akbar Nur; Masfuri; Setyowati; Achmad Fauzi Kamal; Trevino Aristarkus Pakasi
Journal Of Nursing Practice Vol. 8 No. 3 (2025): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jnp.v8i3.673

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Background: Traffic accidents remain a major public health concern globally, particularly in developing countries like Indonesia, which ranks among the highest in road traffic-related mortality. Indonesia, as one of the fourth most populous countries in the world, is at greater risk for increased mortality from traffic accidents. Lower limb fractures are frequently associated with considerable morbidity and lengthy hospital stays. Purpose: This study identifies the perceptions and experiences of continuity of care (COC) nurses in lower limb fracture patients. Methods: This research utilizes a descriptive qualitative model with a phenomenology approach. Researchers recruited respondents after obtaining ethical clearance and an approval letter from West Sulawesi Provincial Hospital. In this study, 5 participants were determined according to the inclusion criteria set by the researcher. The data collection process was carried out by conducting a Focus group Discussion (FGD) for 40–60 minutes. During the FGD, the researchers used FGD notes and field notes. The analysis in this study used content analysis. Results: This study explored nurses' perceptions and experiences of continuity of care (COC) fracture patients in the lower extremity. This study identified four themes, namely, continuity of care (COC) in fracture patients, perceived physical discomfort, support needs in ambulating, and support for improving nurse competency. Conclusion: The implementation of COC can be a solution to the physical discomfort experienced by patients. Nurse support, family support, interprofessional support, and hospital support are needed so that COC can be implemented properly to improve musculoskeletal recovery and sustainable independence in lower limb fracture patients. The hope of the participants, in addition to motivation and the availability of tools for ambulation exercises, should be provided in the surgical room, especially in the treatment room for patients with musculoskeletal system disorders.
Adipose-derived mesenchymal stem cells enhance regeneration in a chronic peripheral sciatic nerve injury Sprague-Dawley rat model Widodo, Wahyu; Dilogo, Ismail Hadisoebroto; Kamal, Achmad Fauzi; Antarianto, Radiana Dhewayani; Wuyung, Puspita Eka; Siregar, Nurjati Chairani; Octaviana, Fitri; Kekalih, Aria; Suroto, Heri; Aprilya, Dina; Canintika, Anissa Feby
Medical Journal of Indonesia Vol. 34 No. 3 (2025): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257780

Abstract

BACKGROUND Obtaining optimal functional outcomes in patients with chronic peripheral nerve injuries (PNIs) remains challenging due to the limited regeneration of the neuromuscular junction (NMJ). Adipose-derived mesenchymal stem cells (AD-MSCs) can differentiate into Schwann-like cells, secrete neurotrophic factors, and recruit native Schwann cells. This study aimed to analyze the effects of AD-MSCs on functional outcomes in a chronic PNI model. METHODS An in vivo study was performed using 20 male Sprague-Dawley rats with chronic PNI of the right sciatic nerve. Rats were divided into two groups: the AD-MSC group (n = 10), receiving human AD-MSC injections in the NMJ; and the control group (n = 10), receiving normal saline injections. Walking track analysis and electrophysiological assessments were performed 8 weeks after the nerve repair. Postmortem gastrocnemius muscle weights and immunohistochemical examinations were also performed. RESULTS The AD-MSCs showed significantly larger fiber diameters than the control group (45.54 [13.1] versus 35.46 [6.64]; p = 0.011). While clinical, electrophysiological, and gastrocnemius muscle weight data suggested a trend toward improved outcomes in the AD-MSCs group, the differences were not statistically significant. CONCLUSIONS AD-MSC implantation may enhance nerve regeneration, as demonstrated by a better outcome profile in the AD-MSCs group.