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All Journal e-GIGI e-CliniC Jurnal e-Biomedik JURNAL BIOMEDIK
Martha M. Kaseke
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology

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Karakteristik Gambaran Histologis Paru-Paru Pasien COVID-19 Gaghaube, Andre M.; Kaseke, Martha M.; Kalangi, Sonny J. R.
e-Biomedik Vol 9, No 1 (2021): eBiomedik
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ebm.v9i1.31896

Abstract

Abstract: Severe acute respiratory syndrome coronavirus (SARS-COV-2) is an infectious disease caused by coronavirus. Coronavirus (COVID-19) first attacks the upper respiratory system such as the nose, mouth, throat even the lungs and can trigger symptoms of fever and cough (pneumonia) resulting in changes in lung organ tissue during histological examination. This study aimed to determine the characteristics of the histological picture of the lungs of COVID-19 patients. This research uses a literature review research method. Based on 12 research reports analyzed in this research, the most common characteristic of histological features found in 12 research report journals is the finding of a diffuse alveolar damage pattern. Diffuse alveolar damage is a condition of acute lung injury which is accompanied by an acute phase with edema, a hyaline membrane, and inflammation followed by an organizing phase, where there is hyperplasia of type II pneumocytes, there is also fibrin or intra-alveolar protein. In conclusion, the characteristics of the histological features of the lungs most commonly found in COVID-19 patients are the findings of a diffuse alveolar damage pattern, which is a condition of acute lung injury and an acute phase with edema, hyaline membrane, and inflammation followed by an organizing phase, namely there is hyperplasia of type II pneumocytes, there is also fibrin or intra-alveolar proteinKeywords: lung histology, COVID-19.  Abstrak: Severe acute respiratory syndrome coronavirus (SARS-COV-2) adalah sebuah penyakit menular yang disebabkan oleh coronavirus. Coronavirus (COVID-19) pertama kali menyerang sistem pernapasan bagian atas seperti hidung, mulut, tenggorokan bahkan sampai ke paru – paru dan dapat memicu gejala demam dan batuk (pneumonia) sehingga terjadi perubahan jaringan organ paru – paru  pada saat dilakukan pemeriksaan histologi. Penelitian bertujuan untuk mengetahui karakteristik gambaran histologis paru – paru pasien COVID-19. Penelitian ini menggunakan metode penelitian literature review. Berdasarkan 12 laporan penelitian yang di analisis pada penelitian ini, karakteristik gambaran histologis yang paling umum ditemukan pada 12 jurnal laporan penelitian yaitu terdapat temuan pola diffuse alveolar damage. Diffuse alveolar damage merupakan kondisi cedera paru akut atau acute lung injury yang disertai dengan fase akut dengan adanya edema, terdapat membran hialin, dan inflamasi di ikuti dengan fase pengorganisasian yaitu terdapat hiperplasia pneumosit tipe II, juga terdapat fibrin atau protein intra-alveolar. Sebagai simpulan, karakteristik gambaran histologis paru – paru yang paling umum ditemukan pada pasien COVID-19 adalah temuan pola diffuse alveolar damage yang merupakan kondisi cedera paru akut atau acute lung injury serta fase akut dengan adanya edema, terdapat membran hialin, dan inflamasi di ikuti dengan fase pengorganisasian yaitu terdapat hiperplasia pneumosit tipe II, juga terdapat fibrin atau protein intra-alveolarKata Kunci: histologi paru, COVID-19
Nervus Olfaktorius: Dasar, Klinis Medis, dan Psikologis Ruru, Pingkan M.; Pasiak, Taufiq F.; Kaseke, Martha M.
eBiomedik Vol 9, No 1 (2021): eBiomedik
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ebm.9.1.2021.31895

Abstract

Abstract: The olfactory nerve is the first cranial nerve. Olfactory disorders can have a negative impact on health and quality of life and affect human psychology. The aim of this study is to determine the basic anatomical, clinical medical and psychological picture of the olfactory nerve. This study was in the form of a literature review. Literature is taken from one database, namely PubMed. The keywords used were olfactory nerve anatomy AND clinical AND psychology. After being selected with inclusion and exclusion criteria, 11 literature will be reviewed. Research from 11 literature reviewed found the basic anatomy of the olfactory nerve. Clinical disorders such as anosmia, hyposmia, phantosmia can occur in several non-neurodegenerative and neurodegenerative events or diseases, namely head injury trauma, Alzheimer's, Parkinson's and COVID-19. Psychological issues related to emotional and psychiatric disorders are also related to smell. In conclusion, the first cranial nerve is the olfactory nerve or the olfactory nerve, which clinically can occur in neurogenerative and non-neurodegenerative diseases. Smell and its disturbances can have a psychological impact.Keywords: olfactory nerve, anatomy, clinical, psychology.  Abstrak: Nervus olfaktorius merupakan saraf kranial pertama. Gangguan olfaktorius dapat berdampak buruk pada kesehatan dan kualitas hidup serta memengaruhi psikologis manusia. Tujuan penelitian untuk mengetahui gambaran dasar anatomi, klinis medis dan psikologis dari nervus olfaktorius. Penelitian ini dalam bentuk literature review. Literatur diambil dari  satu database yaitu PubMed. Kata kunci yang digunakan yaitu olfactory nerve anatomy AND clinical AND psychology. Setelah diseleksi dengan kriteria inklusi dan eksklusi didapatkan 11 literatur yang akan di review. Hasil penelitian dari 11 literatur yang di review didapatkan anatomi dasar nervus olfaktorius. Gangguan klinis seperti anosmia, hiposmia, phantosmia dapat terjadi pada beberapa kejadian atau penyakit non-neurodegeneratif dan neurodegeneratif yaitu Trauma cedera kepala, Alzheimer, Parkinson dan COVID-19. Psikologis yang berkaitan dengan emosional dan gangguan psikiatri juga berhubungan dengan penciuman. Sebagai simpulan, saraf kranial pertama adalah nervus olfaktorius atau disebut saraf penciuman, secara klinis bisa terjadi pada penyakit neurogeneratif dan non-neurodegeneratif. Penciuman dan gangguannya dapat memengaruhi psikologis.Kata kunci: Saraf olfaktori, anatomi, klinis, psikologi.
Analisis Perilaku Aktivitas Fisik selama Pembatasan Sosial pada Dewasa Muda Rau, Elim P. E.; Kaseke, Martha M.; Kairupan, Bernabas H. R.
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.34434

Abstract

Abstract: Social distancing due to the covid-19 outbreak requires everyone to stay at home to reduce the transmission of covid-19. However, staying at home tends to reduce physical activity which is important to improve our health. This study was aimed to analyze the behavior of physical activity during social distancing among young adults based on predisposing factor, enabling factor, and reinforcing factor. This was a qualitative study with a case study using the depth-interview method. There were six informants of youth members of GMIM Elim Kolongan, Tomohon Satu obtained by using a purposive sampling technique based on the principles of suitability and adequacy. The instrument was the researcher himself using interview guides, notebooks, voice recorders, and cameras. Data were obtained from in-depth interview and direct observation and were analysed by using content analysis. The results showed that based on predisposing factor, physical activities were well implemented in terms of knowledge, attitudes, beliefs, values, and perceptions to increase immunity. Based on enabling factors, physical activities were well implemented since the informants had facilities for physical activities. Moreover, based on reinforcing factors, physical activites were well implemented due to supporting people about the importance of physical activity. In conclusion, during social distancing the behavior of physical activity of young adults has been well implemented.Keywords: physical activity; social distancing Abstrak: Pembatasan sosial akibat adanya wabah covid-19 mewajibkan semua orang untuk tinggal di rumah untuk mengurangi penularan covid-19. Tinggal di rumah berpeluang untuk tidak melakukan aktivitas fisik yang dibutuhkan untuk meningkatkan kesehatan. Penelitian ini bertujuan untuk menganalisis perilaku aktivitas fisik selama pembatasan sosial pada dewasa muda berdasarkan peranan faktor predisposisi, faktor pendukung, dan faktor pendorong. Jenis penelitian ialah kualitatif dengan studi kasus menggunakan metode depth-interview. Informan berjumlah enam orang anggota pemuda GMIM Elim Kolongan Wilayah Tomohon Satu. diambil menggunakan teknik purposive sampling yang didasarkan pada prinsip kesesuaian (approppiateness) dan kecukupan (adequacy). Instrumen penelitian ialah peneliti itu sendiri dengan menggunakan pedoman wawancara, buku catatan, perekam suara, dan kamera. Pengumpulan data dilakukan dengan wawancara mendalam dan observasi langsung. Analisis data menggunakan content analysis. Hasil wawancara mendalam dan observasi dokumen menun-jukkan bahwa aktivitas fisik berdasarkan faktor predisposisi berjalan baik dilihat dari penge-tahuan, sikap, kepercayaan, serta nilai dan persepsi yang direspon untuk meningkatkan imunitas tubuh. Aktivitas fisik berdasarkan faktor pemungkin berjalan dengan baik, dilihat dari informan yang memiliki fasilitas untuk melakukan aktivitas fisik. Aktivitas fisik berdasarkan faktor pendorong berjalan baik karena terdapat dukungan dari orang sekitar tentang pentingnya aktivitas fisik. Simpulan penelitian ini ialah perilaku aktivitas fisik selama pembatasan sosial pada dewasa muda telah dilaksanakan dengan baik.Kata kunci: aktivitas fisik; pembatasan sosial
Dampak Pandemi Coronavirus Disease-19 terhadap Mutu Pelayanan Kemoterapi di Ruang Delima RSUP Prof. Dr. R. D. Kandou Manado Nurani, Dian; Kaseke, Martha M.; Mongan, Arthur E.
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.33490

Abstract

Abstract: Covid-19 pandemic has an impact on health services in hospitals, especially in chemotherapy rooms. This study was aimed to analyze the quality of health services dimensions, as follows: reliability, responsiveness, assurance, empathy, and tangible. This was a quantitative study using a cross sectional design. Subjects were adult cancer patients who received chemotherapy services before and during the Covid-19 pandemic in 2020 at Delima chemotherapy room of Prof. Dr. R. D Kandou Hospital Manado and met the inclusion criteria of 30 people, using a five-dimensional health service quality questionnaire. Data analysis was performed univariately and bivariately using the statistical Wilcoxon test p<α (0.05). The results showed that the reliability average before the pandemic was 89.60% and during the pandemic was 88.27% (p=0.008); the responsiveness average before the pandemic was 84.27% and during the pandemic was  83.47% (p=0.000); the assurance average before the pandemic was 95.47% and during the pandemic was 95.73% (p=0.157); the empathy average before the pandemic was 92.53% and during the pandemic was 92.27% (p=0.157); the tangible average before the pandemic was 78.53% and during the pandemic was 84.40% (p=0.000). In conclusion, there were differences in service qualities of reliability, responsiveness, and tangible dimensions but there were no differences in service qualities of assurance and empathy dimensions before and during the Covid-19 pandemic to patients at Delima room of Prof. Dr. R. D. Kandou Hospital Manado.Keywords: Covid-19; chemotherapy; quality of service Abstrak: Pandemi Covid-19 memberi dampak terhadap pelayanan kesehatan di rumah sakit, terutama di ruang kemoterapi. Penelitian ini bertujuan untuk menganalisis mutu pelayanan kesehatan dimensi reliability, responsiveness, assurance, empathy, dan tangible. Jenis penelitian ialah kuantitatif dengan desain potong lintang. Subjek penelitian ialah pasien kanker dewasa yang mendapatkan pelayanan kemoterapi di ruang Delima RSUP Prof. Dr. R. D Kandou Manado sebelum dan pada masa pandemi Covid-19 tahun 2020 yang memenuhi kriteria inklusi sebanyak 30 orang. Penelitian ini menggunakan kusioner lima dimensi mutu pelayanan kesehatan. Analisis data dilakukan secara univariat dan bivariat dengan menggunakan uji statistik Wilcoxon p<α (0,05). Hasil penelitian mendapatkan dimensi mutu sebagai berikut: reliability, rerata sebelum pandemi (89,60%) dan masa pandemi (88,27%) (p=0,008); responsiveness, rerata sebelum pandemi (84,27%) dan masa pandemi (83,47%) (p=0,000); assurance, rerata sebelum pandemi (95,47%) dan masa pandemi (95,73%) (p=0,157); empathy, rerata sebelum pandemi (92,53%) dan masa pandemi (92,27%) (p=0,157); tangible, rerata sebelum pandemi (78,53%) dan masa pandemi (84,40%) (p=0,000). Simpulan penelitian ini ialah terdapat perbedaan mutu pelayanan dalam dimensi reliability, responsiveness, dan tangible namun tidak terdapat perbedaan mutu dalam dimensi assurance dan empathy antara sebelum dan pada masa pandemi Covid-19 terhadap pasien di ruang Delima RSUP Prof. Dr. R. D. Kandou Manado.Kata kunci: Covid-19; kemoterapi; mutu pelayanan kesehatan
Co-Authors Allo, Silva O. L. Arie, Febryola Arthur E. Mongan B H. R. Kairupan Dian Nurani, Dian Djon Wongkar Enny F. S. Lumuhu, Enny F. S. Fariz R Kawulusan, Fariz R Gaghaube, Andre M. George N. Tanudjaja Legoh, Christantio Marthing, Selvira E. Pontoh, Larisa M. Rau, Elim P. E. Riandy A. T. Pattuju Ruru, Pingkan M. Sonny J. R. Kalangi Sonny J.R. Kalangi Taufiq F. Pasiak Togatorop, Desy Wulan G. Parengkuan, Wulan G. Yoczhan A. Wijaya, Yoczhan A.