Ajeng Viska Icanervilia
Departemen Radiologi, Fakultas Kedokteran Kesehatan Masyarakat Dan Keperawatan, Universitas Gadjah Mada Department Of Health Sciences, University Of Groningen

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The relationship between vitamin A and ferritin towards malondialdehyde level among Javanese male smokers Ajeng Viska Icanervilia; . Sunarti; Ahmad Hamim Sadewa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1038.144 KB)

Abstract

Cigarette smokes produce a large number of oxidants and promote secretion of ferritin byalveolar macrophages which are potential to encourage the lipid peroxidation. Malondialdehyde(MDA) is used as a parameter of lipid peroxidation. The study was aimed to evaluate therelationship between blood level of vitamin A and ferritin and MDA among Javanese malesmokers. Sixty men who lived in Purworejo District, Central Java, Indonesia comprising 30smokers as case group and 30 nonsmokers as control group were involved in this study. Bloodsample was obtained from cubiti vein and then centrifuged to obtain plasma or serum. Blood levelsof vitamin A, ferritin and MDA were measured by HPLC, ELISA and spectrophotometric methods,respectively. The result showed that the blood vitamin A, ferritin, and MDA levels in smokers were25.09±9.51μg/dL, 35.50±24.17ng/dL, 1.15±0.42μg/L, respectively, whereas in non smokers, theywere 26.11±9.19 μg/dL, 38.60±15.25 ng/dL, 1.06±0.50 μg/L, respectively. Therewas no significantdifference of the blood vitamin A, ferritin, and MDA levels between smokers and the non smokers(p>0.05). The linear regression analysis indicated that there was negative relationship betweenblood vitamin A and MDA levels although it was not significant (p=0.052), while blood ferritin andMDA levels had a significantly positive relationship (p=0.010). In conclusion, the low level of bloodvitamin A among cigarette smokers does not lead to high blood MDA level, while high level of bloodferritin among smokers leads to high blood MDA level. 
Cost-effectiveness of screenings for mental health in pregnancy: A systematic review Kartikasari, Indah Dwi; Rahayu, Widya; Andriani, Novita; Pramesti, Sekar Ajeng; Safitri, Juliana; Icanervila, Ajeng Viska; Astuti, Andari Wuri
JHeS (Journal of Health Studies) Vol. 8 No. 1 (2024): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.3665

Abstract

Mental disorders posses significant obstacles both during and after pregnancy for many women. Birth weight, premature birth, perinatal and infant deaths, postpartum psychopathology, emotional difficulties, inappropriate behavior in children and adolescents, and adverse effects on other people are just a few of the negative impacts that mental disorders are linked to during pregnancy in that family. Women with mental disorders may experience issues after giving birth, affecting their health throughout pregnancy. Infections, including depression, frequently go undiagnosed and receive subpar treatment despite routine interactions with medical providers during pregnancy. Hormonal changes impact Mother's body movements; for example, she moves more slowly and gets exhausted more rapidly. Pregnant ladies who are in this scenario tend to become indolent. A systematic assessment of research findings on the effectiveness of economic evaluation of mental health screening instruments during pregnancy is frequently used to encourage early detection of mental health in pregnant women as maternal reactions become more sensitive, irritable, and irritable. These investigations mostly used the EPDS and PHQ-9. For the systematic review portion of this investigation, the PRISM ScR 2020 Flowchart was employed, and the A search of the literature was done using the databases Pubmed and Whiley. This article was assessed using the CHEC-Extended checklist. Two reports satisfied the inclusion criteria after an investigation of 890 chosen papers. The systematic review identified three themes: cost, effectiveness, and threshold. Given the variety of treatments used to treat mental health issues in pregnant women, it is clear that using two approaches rather than just one will result in greater cost-effectiveness
Cost-effectiveness of gestational diabetes screening in middle-income countries: a systematic review Annisa, Pariqa; Br Karo, Deliana; Ratnaningrum, Asti; Samosir, Yohana; Astuti, Andari Wuri; Icanervilia, Ajeng Viska; De Moniz, Maria Fatima
Jurnal Kebidanan dan Keperawatan Aisyiyah Vol. 20 No. 1 (2024): Juni
Publisher : Universitas Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jkk.3636

Abstract

The majority of GDM occurs in low- and middle-income countries. GDM is associated with increased maternal and infant complications as well as an increased burden of health financing. Accurate and cost-effective screening is needed for prevention and further treatment. Unfortunately, there is a lack of research on the cost-effectiveness of GDM screening in middle-income countries. The objective of this study was to uncover scientific proof concerning the cost-effectiveness analysis of screening for gestational diabetes in middle-income countries. We conducted a systematic review using Pubmed and ScienceDirect. Four reviewers screened the title and abstract of each article, followed by the selection of the full text based on the inclusion criteria (cost-effectiveness analysis studies of GDM screening and original research). Quality articles were assessed using the CHEC-Extended tool. A total search of 1239 articles found 3 studies that met the inclusion criteria. A screening program is more cost-effective than no screening, this represents a savings of $1,329,671. The ICER value is less than 3x GDP per capita, which indicates that the intervention is cost-effective. Compared to two-step screening, one-step screening is more likely to be cost-effective since it detects more cases. As the prevention of DALYs is mainly due to the prevention of T2DM, middle-income countries should focus more on postnatal care for women with GDM in the future. It is advised that long-term follow-up studies be a major focus of future research in order to evaluate the follow-up GDM screening intervention's possible long-term health benefits and financial effects.
Resilience in Healthcare: A Hospital-based Investigation of Breast Cancer Diagnostics Amid the Pandemic in Indonesia Choridah, Lina; Anwar, Sumadi Lukman; Heriyanto, Didik Setyo; Handoko, Alberta Vania; Sumoro, William; Icanervilia, Ajeng Viska; Rengganis, Anggraeni Ayu
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1166

Abstract

Background: Widespread disruptions in healthcare services have occurred due to ongoing challenges during the pandemic. The tremendous impacts have struck countries with limited resources, greater distances of geographical access to healthcare services, and a shortage of healthcare personnel. Long delay of diagnosis and disruption in patient care affects the long-term prognosis of breast cancer. This study was conducted to investigate the effects of the COVID-19 pandemic and government-mandated social restrictions on the provision of diagnostic services for breast cancer patients in a tertiary referral hospital. The study aimed to explore how travel restrictions and patients' apprehension about COVID-19 exposure have contributed to notable declines in diagnostic and treatment procedures for breast cancer within this healthcare setting. Methods: This study was retrospective design and used a hospital registry to collect information on demographics, imaging, and pathology from January 2018 to September 2021.  Breast ultrasound  (US) and mammography data were collected from the Picture Archiving and Communication System (PACS), while pathology data were collected from e-medical records. The descriptive statistics of the annual total volume of imaging and pathological examinations were interpreted and statistics were only calculated for diagnostics mammography. Results: Between 2018 and 2021, the volume of monthly breast sonograms drastically decreased by 65% in 2020 and 2021 during the pandemic, while mammography significantly reduced by more than 40% from the 2019 levels. Breast US and mammography procedures were significantly lower during the first and second waves of the pandemic in March until May 2020 and June until September 2021, respectively. Although the proportion of breast ultrasound-guided fine-needle aspiration biopsy (FNAB) increased year by year, the number of FNAB for primary breast lesions significantly decreased by 84% in 2020 and 2021. Conclusions: We observed significant decreases in diagnostic procedures for breast cancer. Reconfiguration of breast cancer care scheduling is required to accommodate the potential for increased hospital visits after the travel restrictions.
Evaluasi Pemanfaatan PACS dan RIS Rumah Sakit Provinsi Yogyakarta, Indonesia Icanervilia, Ajeng Viska; Choridah, Lina; Pribadi, Amri Wicaksono; Rahman, Afif; Gusti, Abdi Marang; Huwaida, Azizah; Kusumasari, Dyan Pramandita Windu; Kusumawardani, Aurisa Winda; Frinces, Freshilla Sonia; Setyawan, Nurhuda Hendra
Jurnal Kesehatan Vokasional Vol 9, No 1 (2024): February
Publisher : Sekolah Vokasi Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkesvo.92887

Abstract

Latar   Belakang:    Permintaan pemeriksaan radiologi di kalangan profesional kesehatan terus meningkat. Meskipun Picture Archiving and Communication System (PACS) dan Radiology Information System (RIS) telah diterapkan di RSUP Dr. Sardjito selama dua tahun, tetapi sistem tersebut masih kurang dimanfaatkan. Sistem tersebut sangat penting diterapkan untuk interpretasi yang akurat dan distribusi hasil pencitraan yang tepat waktu.Tujuan: Penelitian ini bertujuan untuk mengevaluasi pemanfaatan PACS dan RIS oleh tenaga medis di RSUP Dr. Sardjito.Metode: Penelitian ini merupakan penelitian kualitatif dengan metode wawancara mendalam. Responden dipilih berdasarkan metode purposive-maximum variety sampling. Metode wawancara menggunakan rekaman audio dan transkrip secara verbatim yang dianalisis secara tematik.Hasil: Penelitian ini menghasilkan 3 tema, yaitu: a) Manfaat PACS  dan RIS; b) Feedback terhadap PACS   dan  RIS; c) Pelatihan meningkatkan pemahaman & pemanfaatan PACS   dan RIS. PACS dan RIS dapat mempersingkat waktu pelayanan kesehatan dan membantu staf medis bekerja secara efisien. Selain itu, sosialisasi dan pelatihan PACS dan RIS juga membawa dampak positif dalam implementasinya, meskipun beberapa responden masih mengandalkan hard film karena keterbatasan akses komputer.Kesimpulan: Penerapan PACS dan RIS meningkatkan kualitas pelayanan rumah sakit. Optimalisasi pemanfaatan sistem PACS dan RIS memerlukan lebih banyak komputer di rumah sakit, pembaruan fitur di telepon seluler, dan pelatihan bagi pengguna