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All Journal Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology AL KAUNIYAH Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Indonesian Journal of Biotechnology Panrita Abdi - Jurnal Pengabdian pada Masyarakat BIOPROSPEK BIOEDUSCIENCE Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Abditani : Jurnal Pengabdian Masyarakat Community Development Journal: Jurnal Pengabdian Masyarakat
Retno Aryani
Jurusan Biologi FMIPA Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Public Health Veterinary Other

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Subchronic Toxicity Test of Indian Almond (Terminalia catappa) Leaves Water Extract on The Liver Histology of Mice (Mus musculus) Nugroho Rudy; Ni Cening Sri Puspa; Retno Aryani; Widha Prahastika; Rudianto Rudianto; Hetty Manurung
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425173

Abstract

Background: Indian almond (Terminalia catappa) is used as an alternative medicine by the community to treat various diseases. However, limited research has been conducted on the subchronic toxicity of Indian almond water extracts on the liver. Present study aimed to determine the subchronic toxic effects of Indian almond leaf water extract on the liver histology of mice and to evaluate the safe dose of Indian almond leaf water extract with various doses (125, 250, 500, 750 and 1000 mg/kg). Methods: In total of 33 male mice were randomly divided into 11 groups, each group consisting of three mice as replication. For 30 days, mice in five treatment groups were orally treated every day with water extracts of green Indian almond leaf while other five groups were given water extracts of brown Indian almond leaves and compare with control group. At the end of day 30, all mice were sacrificed, and hepar was taken out for histological preparations. The histopathological changes in the liver was observed and assessed based on histological damage in the term of degeneration and necrosis. Results: The administration of green and brown Indian almond water extract at doses of 125, 250, 500, 750 and 1000 mg / kg BB showed a toxic effect on the liver of mice. The toxic effect was due to the high doses, causing a cell swelling damage and increased liver necrosis. Conclusion: Indian almond leaf water extract can cause toxic effects on the liver of mice at the doses implemented.
KETAHANAN PANGAN BERBASIS PETERNAKAN DENGAN PAKAN LOKAL DI BABULU KALIMANTAN TIMUR Rudy Agung Nugroho; Retno Aryani; Julinda Romauli Manulang; Muhammad Fauzi Arif; Rudianto Rudianto; Suhardi Suhardi
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 7 No. 3 (2026): Inpress Vol. 7 No. 3 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v7i3.54760

Abstract

Pembangunan Ibukota Negara Nusantara (IKN) yang berpusat di Kalimantan Timur telah mempercepat urbanisasi dan konversi lahan yang berisiko mengancam ketahanan pangan regional. Salah satu dampak yang paling terasa adalah menurunnya produksi peternakan lokal dan meningkatnya ketergantungan pada pakan ternak impor. Penelitian ini bertujuan untuk meningkatkan pemahaman peternak di Kecamatan Babulu, Penajam Paser Utara, mengenai ketahanan pangan berbasis peternakan, dengan fokus pada kemandirian pakan ternak dari sumber daya lokal. Metode yang digunakan dalam program pengabdian ini adalah sosialisasi interaktif dan kunjungan lapangan ke unit feed mill. Hasil program menunjukkan peningkatan pemahaman peserta tentang pentingnya penggunaan pakan lokal untuk mengurangi ketergantungan pada pakan impor serta dampaknya terhadap pengurangan biaya produksi hingga 30-50%. Program ini juga menunjukkan potensi keberlanjutan peternakan lokal melalui optimalisasi limbah pertanian dan hijauan alam sebagai pakan ternak. Peningkatan kapasitas peternak ini sangat penting untuk mendukung ketahanan pangan nasional, terutama di daerah penyangga IKN yang sedang berkembang.
Co-Authors Andy Nurcahyono Apri Pauci Florentino Ari Susandy Sanjaya, Ari Susandy Christiano Jhonson Didit Suprihanto Hetty Manurung Imam Rosadi Iyut Jaya Toimsar Iyut Toimsar Julinda Romauli Manulang L. Hartanto Nugroho Lariman Lariman Monica Kusneti Muhammad Fauzi Arif Muhammad Fauzi Arif Ni Cening Sri Puspa Nugroho Rudy Nurul Fadila Pudji Astuti Rahma Suci Rudianto Rudianto Rudianto Rudianto Rudianto Rudianto Rudianto Rudy Agung Nugroho Rudy Nugroho Soekarti Moeljopawiro Suhardi Suhardi Sukarti Moeljopawiro Widha Prahastika Widha Prahastika Windi Rosiana Dewi Wulan Iyhig Ratna Sari Yanti Puspita Sari Yanti Sari