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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Kedokteran Sriwijaya Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Yunni Diansari
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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PAIN CHARACTERISTICS OF CENTRAL NERVOUS SYSTEM TUMOR IN MOHAMMAD HOESIN GENERAL HOSPITAL Henry Sugiharto; Yunni Diansari; Sheila Stephanie Chandra
JURNAL KEDOKTERAN DAN KESEHATAN Vol 7, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.629 KB) | DOI: 10.32539/JKK.V7I2.11419

Abstract

Pain is one of the cardinal symptom in tumor patient, especially in Central Nervous System (CNS) tumor. It often impacts patient’s quality of life. The incidence and characteristic of pain have rarely been reported in Palembang, Indonesia. This observational study was planned to investigate the clinical presentation and epidemiology of CNS tumor firstly diagnosed in ward throughout July to December 2018. 99 patients recently diagnosed with CNS tumor were enrolled. From 99 patients, we found 34 patients with tumor associated pain. We further evaluated the information of pain linked with brain tumors via questionnaire and medical record. Of all 34 subjects, the age ranged from 43 to 79 years old with female : male ratio 3:1. Pain was present 100% in spinal tumor and 54% in brain tumor. Clinical characteristics of pain found in brain tumor were typically in ipsilateral lesion (92%), pulsating (76%), moderate intensity (60%), recurrent (84%), not radiating (80%), with frequency of 3-4 times in a week (48%). On the other hand, pain in spinal tumor was generally felt on the site of the lesion (100%), radiating (77.8%), electrical type of pain (44.4%), high intensity (77.8), and constant (88.9%). From this study we conclude that tumor locations can show some different pain characteristics. Therefore careful pain assessment is compulsory to have better understanding and more appropriate management.
Profile of Coagulation Marker and The Influence Factors in Central Nervous System Tumor Yunni Diansari; Mediarty Syahrir; Sri Novianty Yusuf
Majalah Kedokteran Sriwijaya Vol 53, No 2 (2021): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/mks.v53i2.10065

Abstract

Brain tumors have the highest percentage of thrombosis compared to other types of malignancies. Hypercoagulation is a risk for thromboembolic events in patients with malignancy. Hypercoagulation conditions are frequently found in patients with malignancy arising from the aptitude of tumor cells to activate the coagulation system. This condition can be detected through coagulation markers in the blood. This marker is PT, APTT, INR, Fibrinogen and D-Dimer. This research is a descriptive analytic study using secondary data from medical records of patients with central nervous system (CNS) tumors. The inclusion criteria were CNS tumor patients > 18 years old and had been diagnosed with CNS tumor. Coagulation markers are recorded based on the results of the initial laboratory examination upon entering the hospital, consisting of D-Dimer, PT, APTT, Fibrinogen, INR. There were 124 research subjects, consisting of 60 men and 64 women. Most research subjects are in the age range of 40-49 years (54.8%). Hypercoagulation conditions were found in 92.74% of study subjects. The most common accompanying condition was hypertension (22.6%). There were no significant differences in the hypercoagulable conditions in groups with and without accompanying conditions. Hypercoagulation was found in most research subjects. There are no factors that influence the hypercoagulation condition in this study.
Profile of Coagulation Marker and The Influence Factors in Central Nervous System Tumor Yunni Diansari; Mediarty Syahrir; Sri Novianty Yusuf
Majalah Kedokteran Sriwijaya Vol 51, No 4 (2019): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v51i4.10071

Abstract

Brain tumors have the highest percentage of thrombosis compared to other types of malignancies. Hypercoagulation is a risk for thromboembolic events in patients with malignancy. Hypercoagulation conditions are frequentlyfound in patients with malignancy arising from the aptitudeof tumor cells to activate the coagulation system. This condition can be detected through coagulation markers in the blood. This marker isPT, APTT, INR, Fibrinogen and D-Dimer.This research is a descriptive analytic study using secondary data from medical records of patients with central nervous system (CNS) tumors. The inclusion criteria were CNS tumor patients> 18 years old and had been diagnosed with CNS tumor. Coagulation markers are recorded based on the results of the initial laboratory examination upon entering the hospital, consisting of D-Dimer, PT, APTT, Fibrinogen, INR.There were 124 researchsubjects, consisting of 60 men and 64 women. Most research subjects are in the age range of 40-49 years (54.8%). Hypercoagulation conditions were found in 92.74% of study subjects. The most common accompanying conditionwas hypertension (22.6%). There were no significant differences in the hypercoagulable conditions in groups with and without accompanying conditions.Hypercoagulation was found in most research subjects. There are no factors that influence the hypercoagulation condition in this study.
THE COMPARISON OF EFFECTIVENESS AND SAFETY BETWEEN WARFARIN AND RIVAROXABAN IN HYPERCOAGULATED CENTRAL NERVOUS SYSTEM TUMORS Sri noviyanty Yusuf; Yunni Diansari; Mediarty Syahrir; Phey Liana
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v11i1.25056

Abstract

Abstract:                                                                                                                                           Background: Central nervous system (CNS) tumors originate from the brain and spinal cord, and have complications, such as hypercoagulation. The administration of anticoagulants (warfarin and rivaroxaban) has been able to reduce hypercoagulation-related morbidity and mortality, however, the effectiveness and safety of their use has not been well studied. This study aims to compare the effectiveness and safety of anticoagulant drugs between warfarin and rivaroxaban in hypercoagulated CNS tumors. Methods: This was a randomized clinical trial study, double-blinded, conducted on CNS tumor patients from September-November 2020 at Mohammad Hoesin Hospital. The patients were given warfarin and rivaroxaban for 3 weeks. Coagulation status was measured before and after. Data were analyzed using SPSS ver.24. Results: The mean age of 20 patients was 42.70+8.14 years and majority were female (80%), with tumor characteristics were primary (80%), single (85%), and located in the brain (95%). In the warfarin group (n=10), there were significant improvements in PT (p 0.008), INR (p 0.013), Fibrinogen (p 0.041), and D-Dimer (p 0.008) value, also the rivaroxaban group (n=10) in PT (p 0.013), APTT (p 0.012), INR (p 0.028), Fibrinogen (p 0.047), D-Dimer (p 0.032), and Anti Fxa (p 0.028). However, there was no significant difference between groups, except when comparing the Anti Fxa delta (p 0.041). There was 1 person with major bleeding using warfarin, and 1 person (excluded) with GIT bleeding using rivaroxaban. Conclusion: There was a significant improvement of coagulation value in both groups, also side effects were seen as well. Keyword: CNS Tumor, Hypercoagulation, Warfarin, Rivaroxaban
Factors Playing a Role in Sleep Disorders in Post-COVID-19 (Coronavirus Disease) Patients at the Neurology Polyclinic of Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Hasnawi Haddani; Handayani, Sri; Yunni Diansari; Afriani; Mukhlisa; Rifka Humaida; Citra Ananta Avis
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 5 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i5.989

Abstract

Background: Sleep disorders are one of the symptoms frequently reported in post-COVID-19 patients. This study aims to identify factors that play a role in sleep disorders in post-COVID-19 patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: This research was conducted in an analytical observational manner with a cross-sectional design. Data was collected from 100 post-COVID-19 patients treated at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Data were analyzed using the logistic regression test. Results: Factors that play a role in sleep disorders in post-COVID-19 patients are depressive symptoms (OR=2.5; 95%CI: 1.3-4.8); Anxiety symptoms (OR=3.1; 95%CI: 1.6-5.9); Stress level (OR=2.2; 95%CI: 1.1-4.3); Sleep quality before COVID-19 (OR=2.0; 95%CI: 1.0-3.9). Conclusion: Symptoms of depression, anxiety, stress, and sleep quality before COVID-19 are factors that play a role in sleep disorders in post-COVID-19 patients.
Factors Playing a Role in Sleep Disorders in Post-COVID-19 (Coronavirus Disease) Patients at the Neurology Polyclinic of Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Hasnawi Haddani; Handayani, Sri; Yunni Diansari; Afriani; Mukhlisa; Rifka Humaida; Citra Ananta Avis
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 5 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i5.989

Abstract

Background: Sleep disorders are one of the symptoms frequently reported in post-COVID-19 patients. This study aims to identify factors that play a role in sleep disorders in post-COVID-19 patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: This research was conducted in an analytical observational manner with a cross-sectional design. Data was collected from 100 post-COVID-19 patients treated at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Data were analyzed using the logistic regression test. Results: Factors that play a role in sleep disorders in post-COVID-19 patients are depressive symptoms (OR=2.5; 95%CI: 1.3-4.8); Anxiety symptoms (OR=3.1; 95%CI: 1.6-5.9); Stress level (OR=2.2; 95%CI: 1.1-4.3); Sleep quality before COVID-19 (OR=2.0; 95%CI: 1.0-3.9). Conclusion: Symptoms of depression, anxiety, stress, and sleep quality before COVID-19 are factors that play a role in sleep disorders in post-COVID-19 patients.
Co-Authors Afriani Citra Ananta Avis Handayani, Sri Mediarty Syahrir Muhammad Hasnawi Haddani Mukhlisa Phey Liana Rifka Humaida Sheila Stephanie Chandra Sri Novianty Yusuf Sri noviyanty Yusuf Sugiharto, Henry