Johan Kurnianda
Division Of Hematology And Medical Oncology, Department Of Internal Medicine, Faculty Of Medicine, Universitas Gadjah Mada / Dr. Sardjito Hospital Yogyakarta

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Status gizi awal berdasarkan Patient Generated Subjective Global Assessment (PG-SGA) berhubungan dnegan asupan zat gizi dan perubahan berat badan pada penderita kanker rawat inap di RSUP Dr. Mohammad Hosein Palembang Susetyowati Susetyowati; Yenita Yenita; Johan Kurnianda
Jurnal Gizi Klinik Indonesia Vol 7, No 2 (2010): November
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17741

Abstract

Background: Weight loss is commonly detected among cancer patients in their early stages. This presumably happens due to low calory intake and increasing energy requirements which finally lead to malnutrition in cancer patients. Early detection to identify nutrition problems of cancer patients is through screening so as to maximize nutrient intake through nutrition therapy and diet modification and to improve nutrition status as well as quality of life of cancer patients.Objective: The study aimed to identify the relationship between nutrition status based on PS-SGA and nutrient intake and weight loss of cancer patients hospitalized at Dr. M. Hoesin Hospital of Palembang.Methods: The study was observational with prospective cohort study design. In this study the group that had fulfilled inclusion criteria were screened during their early hospitalization (within 24 hours) using patient-generated subjective global assessment score to identify their nutrition problem. Next, the group was divided into 2 smaller groups consisting of one group with malnutrition and another group without malnutrition. Analysis of nutrient intake obtained from foods provided by the hospital and outside the hospital was made to the two groups within 2 weeks of hospitalization using visual comstock and food record. Anthropometric measurement was made to find weight loss the subject of the study.Results: The results of the study showed that there was significant relationship between nutrition status and intake of energy and protein with p=0.000. The result of logistic regression test to nutrition status based on weight changes indicated that there was significant relationship between risk of nutrition and weight changes; patients with risk of nutrition had 7.016 times greater probability for weight loss than those without risk of nutrition (95% C5  2.896-16.997).Conclusion: There was significant relationship between nutrition status and nutrient intake among cancer patients and there was greater probability for weight loss.
Faktor risiko dan asupan isoflavon pada pasien kanker payudara I Wayan Dwija Karyasa; Johan Kurnianda; Herni Astuti
Jurnal Gizi Klinik Indonesia Vol 10, No 4 (2014): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.114 KB) | DOI: 10.22146/ijcn.18876

Abstract

Background: Breast cancer is noncommunicable chronic disease the prevalence of which is increasing all over the world, including in Indonesia and particularly East Java. Causes of breast cancer are unknown. Some studies show risk factors for breast cancer are hormonal, genetic, reproductive and endocrinologic factors. There is the isoflavon compound in soybeans that is known as anti-cancer with anti-estrogen activities.Objective: The study was aimed at identifying risk factor and the difference of isoflavone intake between breast cancer patients and healthy people in hospitals.Method: The study was analytic observational using matched case-control study design at comparison 1:2 with matching on a status of menopause. Cases were positive receptor estrogen breast cancer patients newly diagnosed during the first visit at hospital outpatient Oncologic Surgery Polyclinic. Controls were staff considered healthy based on the result of health examination at Dr. Ramelan Naval Hospital of Surabaya. Cases comprised 49 people and control 98 people taken through consecutive method. Data consisted of an identity of samples, weight, height, isoflavone intake, family history, use of hormone replacement therapy and parity. Intake of isoflavones was obtained from semiquantitative food frequency questionnaire (SQ-FFQ) and statistical test used Chi-Square and Odd Ratio (OR).Results: There was the difference in isoflavone intake and family history between cases and controls (p<0.05) and there was an association between isoflavone intake (OR=2.58; p=0.007) and family history (OR=18; p=0.002) and the incidence of breast cancer. There was no association between the status of obesity, parity, and use of hormone replacement therapy.Conclusion: There are differences in isoflavone intake of breast cancer patients compared with healthy people and there was no difference in the status of obese breast cancer patients compared to healthy individuals and isoflavone intake less 2.85 times the risk of breast cancer compared with adequate intake of isoflavones.