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All Journal JBIO: jurnal biosains (the journal of biosciences) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research
Sumantri, Imam Bagus
Universitas Sumatera Utara
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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UJI PRA KLINIS TOLERANSI GLUKOSA EKSTRAK ETANOL SERTA PENGUJIAN TOKSISITAS AKUT EKSTRAK ETANOL DARI PUGUN TANA (Picria felterrae Lour.) Imam Bagus Sumantri; Sumadio Hadisahputra; Dharma Lindarto; Awaluddin Saragih
JBIO: jurnal biosains (the journal of biosciences) Vol 3, No 2 (2017): Jurnal Biosains
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v3i2.7435

Abstract

Diabetes mellitus merupakan penyakit degeneratif yang memerlukan pengobatan yang intensif. Tanaman tradisional untuk pengobatan diabetes banyak dijumpai di masyarakat dan telah digunakan secara turun temurun. Pugun Tana (Picria felterrae Lour.) merupakan tumbuhan khas yang digunakan oleh masyarakat Dairi untuk pengobatan diabetes. Data hasil penelitian efektifitas sebagai antidiabetes dari Pugun Tana belum banyak dilakukan. Penelitian ini dilakukan bertujuan untuk menguji keamanan dan efektifitas dari Pugun Tanan sebagai antidiabetes sehingga dapat digunakan sebagai tanaman tradisional yang aman dan berkhasiat.Penelitian ini dilakukan dengan karakteristik simplisia daun (penentuan kadar air, penentuan kadar abu total dan tidak larut dalam asam, penentuan kadar sari larut etanol dan penentuan larutan kadar sari larut air). Ekstrak dibuat dalam crude extract dengan metode maserasi-perkolasi.Uji Toksisitas secara akut crude extract daun pugun tana tidak menunjukkan tanda-tanda keracunan dan kematian yang berarti sampai dosis 10.000 mg/kg bb. Crude extract pugun tana (Picria felterrae Lour.) dikategorikan praktis tidak toksis atau toksisitas ringan. Namun, data indeks organ menunjukkan bahwa ada perbedaan dari organ seperti hati, dan perbedaan ini tidak memberikan perbedaan yang berarti dibandingkan dengan dosis lainnya.  Uji Toleransi glukosa dengan pemberian larutan glukosa dosis 5 g/kg bb menunjukkan bahwa pemberian ekstrak etanol pugun tana dosis 50, 100 dan 200 mg/kg BB tersebut menurunkan kadar gula darah tikus yang diberikan glukosa 50%. Suspensi ekstrak pugun tana dosis 100 mg/kg bb memberikan penurunan kadar gula darah hampir sama dengan  suspensi glibenklamid dosis 10 mg/kg bb dan kenaikan dosis ekstrak tidak memberikan efek penurunan kadar gula darah yang lebih baik. Kata kunci:  tikus obesitas, toleransi glukosa, toksisitas akut, picria felterrae, pugun tana
EFFECT OF CASSAVA TUBER PROCESSING ON Candida albicans GROWTH ON MANIHOT DEXTROSE AGAR Patilaya, Popi; Sumantri, Imam Bagus; Keliat, Jane Melita
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 01 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i01.20763

Abstract

This study evaluated the effect of cassava tuber processing on Candida albicans growth on Manihot Dextrose Agar (MDA). The sliced cassava tubers were divided into three groups. G1 was milled and dried in an oven at 60°C. G2 was directly dried in the oven. G3 was milled without drying. Each group was soaked in distilled water (1,000 mL) for 15 min and filtered with a flannel cloth. The filtrate was oven-dried, then pulverized to obtain the cassava powder. The powder (8 g) was combined with dextrose (20 g) and agar (15 g). The mixture was suspended in distilled water (1,000 mL), boiled, and sterilized at 121°C for 15 min. The solution was placed into a petri dish and allowed to form agar media. The media derived from G1, G2, and G3 were considered as F1, F2, and F3. A suspension of C. albicans was cultured on the media and incubated for 48 h. The fungal growth was observed by calculating the viable colonies. The data were analyzed with one-way ANOVA and followed by Duncan’s test at the confidence level of 95%. The results showed that C. albicans grown on media F1, F2, and F3 had colony numbers of 128±2.08 x 105 cfu/mL, 64±5.57 x 105 cfu/mL, and 44±3.51 x 105 cfu/mL, respectively. Statistical analysis indicated a significant difference in the fungal growth on the three media (p < 0.05). This study proved that the processing methods of cassava tubers for MDA significantly affected the growth of C. albicans.
Empowering Indonesian Da’wah Academy North Sumatera Students through AI-Driven Content Creation Widyawati, Tri; Andriyani, Yunilda; Bin Nur, Taufiq; Bagus Sumantri, Imam; Tarisa Olivia; Muhammad Rozan Fawwaz Syariq; Septia Nugraha; Saddam Haikal; Rezka Zuhra Maulida
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 9 No. 2 (2024): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v9i2.18293

Abstract

The rapid development of technology, especially in the field of artificial intelligence (AI), has created new opportunities for the creation of creative content and provided fresh approaches to captivate viewers and deliver important messages. The purpose of this community service project is utilizing AI technology to create preaching content for the students of the Indonesian Da'wah Academy located in North Sumatra. The activity is carried out in four stages, starting with a socialization of the activity plan to the partner and participants (students), followed by a presentation of training materials, independent learning, and task presentations. A number of AI-powered platforms are unveiled, including those for image, video and voice generation. The training emphasized the importance of digital literacy and ethical content creation within the context of dakwah (Islamic propagation). By the end of the program, a Student Content Creator Unit was established as a unit that will continue to enhance students' abilities in the digitalization of content. The evaluation was conducted in the form of a questionnaire, with results reflecting the enthusiasm and satisfaction of the participants regarding the training they attended. The program's success highlights the potential of AI in empowering students to enhance their creative skills while promoting positive and constructive narratives in the digital age.
Co-Authors Andriyani, Yunilda Awaluddin Saragih bin Nur, Taufiq dharma Lindarto, dharma Keliat, Jane Melita Muhammad Rozan Fawwaz Syariq Patilaya, Popi Rezka Zuhra Maulida Saddam Haikal Septia Nugraha Sumadio Hadisahputra Tarisa Olivia Tri Widyawati, Tri