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All Journal EduChemia: Jurnal Kimia dan Pendidikan Health Information : Jurnal Penelitian Cermin Dunia Kedokteran Masyarakat Mandiri: Jurnal Pengabdian Dan Pembangunan Lokal
Rifdah Hanifah
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Bioaktivitas Ekstrak Makroalga Sargassum sp. dan Gracilaria sp. terhadap Korosi Mikrobial T. Ferrooxidans Isriyanti Affifah; Fida Madayanti Warganegara; Bunbun Bundjali; Rahmat Firman Septiyanto; Irah Namirah; Rifdah Hanifah
EduChemia (Jurnal Kimia dan Pendidikan) Vol 4, No 2 (2019)
Publisher : Department of Chemical Education Faculty of Teacher Training and Education Universitas Su

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (422.792 KB) | DOI: 10.30870/educhemia.v4i2.6047

Abstract

Korosi mikrobial merupakan korosi yang disebabkan oleh adanya pertumbuhan mikroba. Korosi jenis ini dapat mempengaruhi dan mempercepat proses terjadinya korosi karena adanya mikroba. Pipa bawah laut merupakan salah satu material yang sering ditumbuhi bakteri penyebab korosi. Korosi akibat aktivitas mikroba dapat menyebabkan kebocoran pipa bawah laut yang dapat mencemari lingkungan dan biota laut lainnya. Mikroba tersebut tumbuh dan menetap pada pipa selama beberapa lama dan menyebabkan perkaratan pipa. Salah satu mikroba yang dapat menyebabkan korosi microbial adalah bakteri aerob yang berperan aktif dalam proses microbial korosi yaitu bakteri Thiobacillus. Bakteri jenis ini mampu menghasilkan kondisi lingkungan asam yang bersifat korosif hasil dari oksidasi sulfur menjadi asam sulfat. Pada penelitian ini ditentukan laju inhibisi korosi dan dosis optimum makroalga yang digunakan untuk mendapatkan hasil inhibisi yang optimal. Ekstrak metanol Gracilaria sp. dan Sargassum sp. mampu menginhibisi pertumbuhan T. ferooxidans pada dosis 300µL dan 400µL dalam 10 ml media. Nilai LC50 ekstrak Sargassum sp. adalah 483 µL sedangkan untuk ekstrak Gracilaria sp. adalah 461 µL dalam 25 ml media.
Bakteri Anaerob Clostridium botulinum dan Toksin yang Dihasilkannya Conny Riana Tjampakasari; Rifdah Hanifah
Cermin Dunia Kedokteran Vol 49, No 5 (2022): Jantung dan Saraf
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i5.1849

Abstract

C. botulinum adalah salah satu bakteri paling patogen karena dapat menghasilkan botulinum neurotoxin (BoNT) yang mematikan. Terdapat 3 jenis botulisme, yaitu botulisme keracunan makanan, botulisme inhalasi, dan botulisme luka. Meskipun kejadian botulisme jarang, namun harus diwaspadai karena cukup fatal. Sebagian besar kasus botulisme pada manusia disebabkan oleh makanan kaleng yang dipersiapkan di rumah. Isolasi dan identifikasi C. botulinum dapat dilakukan dengan pemeriksaan pewarnaan Gram, kultur, dan identifikasi, sedangkan deteksi toksin dapat menggunakan metode mouse lethality assay, non-lethal mouseassay, dan metode imunologi. Pendekatan molekuler dilakukan melalui uji polymerase chain reaction (PCR) untuk deteksi jenis toksin. Pencegahan botulisme dilakukan dengan teknik penanganan makanan yang tepat. Pemanasan yang memadai dapat membunuh spora bakteri, selain itu segera mengonsumsi makanan yang telah dimasak dapat mencegah C. botulinum bertumbuh. C. botulinum is one of the most pathogenic bacteria because it can produce deadly botulinum neutotoxin (BoNT). There are 3 types of botulism: botulism poisoning, inhalation botulism, and wound botulism. Although the incidence of botulism is rare, the impact is quite fatal. Most cases of botulism in human are caused by canned food prepared at home. Isolation and identification of C. botulinum can be done by Gram staining, culture, and identification, while the detection of toxins can use the mouse lethality assay, non-lethal mouse assay, and immunological methods. Molecular approach can be done through polymerase chain reaction(PCR) examination to detect the toxin type. Prevention can be applied with proper food handling techniques. Adequate heating can kill bacterial spores, and direct consumption can prevent proliferation of C. botulinum.
The Pathogenesis of Fungal Coinfections in COVID-19 Cases: A Literature Review Hanifah, Rifdah; Yasmon, Andi
Health Information : Jurnal Penelitian Vol 15 No 3 (2023): September-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i3.1149

Abstract

Coronavirus disease 2019 (COVID-19) is a disease that attacks the human respiratory tract caused by the SARS-CoV2 virus. Critically ill patients admitted to the ICU, require a ventilator or are hospitalized for a long time are susceptible to fungal coinfection. Several fungi were detected to cause coinfection with COVID-19, such as Candida spp, Aspergillus spp, Mucor spp, and Cryptococcus spp. Research on the mechanism of fungal infection in COVID-19 patients still requires further research, but several possibilities can be associated with both. Several factors that can cause fungal coinfection, including the use of corticosteroids, ventilators, and oxygen masks in COVID-19 patients. The condition of immune dysregulation in COVID-19 patients causes the patient’s body to be unable to fight fungal infections. Some prevention can be done by regularly coordinating the early detection of fungal infections in COVID-19 patients to reduce risk factors and improve routine treatment protocols. If the patient has a fungal infection, treatment can be done using some of the recommended drug combinations. In addition, to maintain the cleanliness of medical devices, especially ventilators, the cleanliness of hospital wards, and the process of handling COVID-19 patients, it is also necessary to pay attention to preventing the transmission of COVID-19 hospitalized patients.
Penguatan Perilaku Hidup Sehat dan Bermoral melalui Edukasi Anti-Narkoba, Anti-Bullying, dan Anti-Korupsi Ekawati Rini Wulansari; Luluk Hermawati; Ghea Farmaning Thias Putri; Rifdah Hanifah; Ainina Al Shadrina; Dwi Widyawati
Masyarakat Mandiri : Jurnal Pengabdian dan Pembangunan Lokal Vol. 2 No. 4 (2025): Oktober: Masyarakat Mandiri : Jurnal Pengabdian dan Pembangunan Lokal
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/masyarakatmandiri.v2i4.2032

Abstract

Early character education plays a fundamental role in shaping a generation that is not only intelligent but also physically healthy, emotionally balanced, and morally responsible. The cultivation of these values from an early age is crucial to equip children with the resilience needed to face various social challenges in the future. This community service activity was designed to increase awareness among elementary school students regarding three critical issues: the dangers of drug abuse, the practices of bullying, and the detrimental impact of corruption. The program was conducted at SDN 1 Citeluk with the participation of approximately 80 students from grades IV to VI. The educational materials were delivered through an interactive approach combining lectures, group discussions, role-playing, and quizzes. This approach was selected to ensure that the learning process was enjoyable, engaging, and easily understood by children at the elementary school level. During the sessions, students were introduced to the basic concepts of drugs, their harmful effects on health and life, and the importance of avoiding them. Additionally, the program emphasized identifying the various forms of bullying—whether physical, verbal, or social—and encouraged students to develop empathy and mutual respect. Another important aspect addressed was corruption, where students were guided to recognize the value of honesty and integrity through relatable examples in daily life. The results of the activity revealed that students were able to clearly understand the dangers of drugs, recognize the different forms of bullying, and provide examples of honest and moral behavior. This indicates that early character education delivered through interactive and participatory methods can effectively enhance children’s comprehension of healthy and moral values. It is expected that similar programs can be carried out sustainably in elementary school settings as part of continuous character-building efforts to support the development of a responsible and ethical young generation
Co-Authors Ainina Al Shadrina Andi Yasmon Bunbun Bundjali Ekawati Rini Wulansari Fida Madayanti Warganegara Ghea Farmaning Thias Putri Irah Namirah Isriyanti Affifah, Isriyanti Luluk Hermawati Rahmat Firman Septiyanto, Rahmat Firman Tjampakasari, Conny Riana Widyawati, Dwi