Widjaja Lukito
SEAMEO-TROPMED Regional Center for Community Nutrition

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Nutritional status of hyperlipidemics elderly in Indonesia according to body mass lndex (study in four Indonesian big cities) Kamso, Sudijanto; Purwantyastuti, Purwantyastuti; Rumawas, Yohanna S.P.; Lukito, Widjaja
Medical Journal of Indonesia Vol 14, No 2 (2005): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.283 KB) | DOI: 10.13181/mji.v14i2.184

Abstract

The objective of this study was to assess the nutritional status of hyperlipidemics elderly. A cross sectional study was undertaken in 4 big cities in Indonesia using multistage random sampling. The respondents were 656 hyperlipidemics and non hyperlipidemics elderly who were the subsample of 1261 sample of a larger population study. Data were collected through anthropometric measurements and biochemical blood analysis. To determine the nutritional status by Body Mass Index (BMI) the criteria used for elderly men and women are as follows, underweight BMI ≤ 18.5 kg/m2, normoweight BMI 18.5 - 24.9 kg/m2, overweight BMI 25 - 29.9 kg/m2, and obese BMI ≥ 30 kg/m2. To determine lipid status, the criteria used are as follows, hyperlipidemics elderly, those who had plasma total cholesterol ≥ 240 mg/dl and or triglycerides ≥ 200 mg/dl. Prevalence of hyperlipidemics in elderly women is higher then elderly men, 56.2% vs 47.0%. The BMI of hyperlipidemics is mostly overweight (60.4%) and obese (57.1%) for elderly men; and mostly normoweight (59.1%) and overweight (59.5%) for elderly women. The prevalence of hyperlipidemics among undernourished elderly men and women were also quite high, 38.7% and 31.6% respectively. (Med J Indones 2005; 14: 97-100)Keywords : BMI, hyperlipidemics, elderly
Fatty acids intake among diverse ethnic groups in Indonesia Hatma, Ratna D.; Lukito, Widjaja; Rumawas, Yohanna S.P.
Medical Journal of Indonesia Vol 14, No 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.551 KB) | DOI: 10.13181/mji.v14i4.203

Abstract

The use of dietary pattern specifically fatty acids intake should prove to be an informative and powerful means to augment our understanding of the role of diet in chronic disease particularly CHD. Cross sectional study was implemented to describe the nutrients intake specifically fatty acids intake of 4 (four) ethnic groups in Indonesia, such as Minangkabau, Sundanese, Javanese and Buginese. The percentage of saturated fatty acid (SAFA) to total energy intakes were around 20%. The percentage of polyunsaturated fatty acid (PUFA) to the total energy were about 4.4% to 4.6% among the Sundanese and the Javanese.While among the other two ethnic groups, the percentage of PUFA to total energy were less, 2.6 % among the Minangkabau and 2.8% among the Buginese ethnic. The percentage of mono unsaturated fatty acid (MUFA) to total energy intake were higher among the two ethnic groups, Sundanese and Javanese (6.1% vs. 5.5%). While the percentages of MUFA between the other two ethnic groups Minangkabau and Buginese ethnic were lower (2.6% vs. 2.8%). Based on the ratio of PUFA: MUFA: SAFA, we could consider that Minangkabau and Buginese ethnic groups both had poor quality of dietary fat pattern. Having the poor quality of dietary fat pattern and higher fat intake, we might take into consideration that the Minangkabau ethnic groups, had higher risk toward dyslipidemia compared to the other three ethnic groups. (Med J Indones 2005; 14:242-8)Keywords: fatty acids intake, SAFA, MUFA, PUFA , ethnic Nutrient intake
Fat free mass index as parameter for nutritional status in non-dialysis chronic kidney disease patients stage 3, 4 and 5 Kumala, Meilani; Lukito, Widjaja; Sastroamidjojo, Soemilah; Prodjosudjadi, Wiguno
Medical Journal of Indonesia Vol 17, No 4 (2008): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1587.488 KB) | DOI: 10.13181/mji.v17i4.325

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The aim of this study is to obtain body composition parameters for early detection of PEM in non dialysis CKD (ND-CKD) patients. The study was carried out using the cross sectional design. The subjects of the study consist of 45 ND-CKD patients and 45 healthy subjects matched for age, gender, height and body mass index (BMI). The nutritional status of patients and healthy subjects were classified based on BMI (WHO, 1995) into low, normal and high nutritional status groups. Fat free mass (FFM), FFM-index (FFM-I) and percentage of fat mass (FM percentage) in patients measured by anthropometric technique showed no significant difference with healthy subjects. Using the BIA  method, FFM and FFM-I were significantly lower in the ND-CKD patients compared to the healthy subjects (p < 0,05). Significant difference in FFM, FFM-I, FM and FM percentage was observed between the patients with different nutritional status. (p < 0,001). Trend analysis statistical test showed that there is linear correlation of FFM, FFM-I and FM with nutritional status classification. FFM, FFM-I, FM and FM percentage in ND-CKD patients were not significantly different between the three stages of CKD. There was an acceptable degree of agreement between BMI with FFM-I for nutritional assessment in ND-CKD patients. The Receiver Operating Curve test showed the cut off points of FFM-I 14.23 kg/m2 to differentiate undernutrition and normal nutritional status in ND-CKD patients. This study showed FFM-I has good correlation with BMI and can be used to differentiate degrees of nutritional status in stage 3, 4 and 5 ND-CKD  patients. FFM-I considered predictor parameters for nutritional status screening in ND-CKD patients. (Med J Indones 2008; 17: 240-7)Keywords: Non dialysis chronic kidney disease, protein energy  malnutrition, body composition, fat free mass, fat free mass index
Adiponectin, total anti-oxidant status, and high sensitivity C-reactive protein in Indonesian men with metabolic syndrome Sartika, Cynthia R.; Lukito, Widjaja; Wijaya, Andi
Medical Journal of Indonesia Vol 18, No 4 (2009): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.348 KB) | DOI: 10.13181/mji.v18i4.369

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Aim: To examine biochemical markers of adiponectin, total anti-oxidant status (TAOS) and high sensitvity C-reactive protein (hsCRP) in individuals with and without metabolic syndrome (MetS).Methods: A cross-sectional study on 36 non-MetS and 36 MetS  subjects was undertaken in Jakarta. Measured indicators were adiponectin, TAOS and hsCRP, apart from weight, height, waist circumference (WC), systolic blood pressure (SBP), diastolic  blood pressure (DBP), and fasting blood glucose (FBG). Odds ratio (OR) of adiponectin, TAOS and hsCRP were calculated to assess risk for the development of MetS. Median values were determined as cutoffs to define high and low values of each parameter. Relationships between adiponectin, TAOS and hsCRP with WC were analyzed by using Spearman correlation analysis, and the contributions of all indicators to the development of MetS were analyzed by using logistic regression.Results: Adiponectin dan hsCRP differed signifi cantly between non MetS and MetS subjects (4.2 + 1.4 vs 3.1 + 1.0 ug/mL) dan (0.97 + 0.92 vs 3.35 + 3.43 mg/L) (p < 0.01), but no signifi cant difference was found in TAOS (1.24 + 0.1 vs 1.28 + 0.2 mmol/L). Adiponectin associated negatively with WC (rs=  -0.436; p < 0.01), while TAOS and hsCRP associated positively with WC (rs= 0.286, p = 0.02 and rs= 0.597, p < 0.01). The odds ratios (ORs) of adiponectin and hsCRP for the   development of MetS were 4 (p = 0.01) and ~6,8 (p < 0.01), respectively; while the risk of subjects with adiponectinhs CRPratio of ≤ 2.31 to develop MetS was 25 times (p < 0.01) those with adiponectin-hsCRP ratio > 2.31.Conclusion: The use of adiponectin-hsCRP ratio increases the predictive power for the occurrence of MetS by 4-6 times the predictive power of adiponectin or hsCRP alone. (Med J Indones 2009; 18: 262-8)Keywords: adiponectin, hsCRP, total anti-oxidant status, metabolic syndrome.
Negative impact of imflammation and insulin resistance on the biogenesis of HDL-c in Indonesian men with metabolic syndrome Sormin, Ida P.; Lukito, Widjaja; Wijaya, Andi; As’ad, Suryani
Medical Journal of Indonesia Vol 19, No 1 (2010): February
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (753.414 KB) | DOI: 10.13181/mji.v19i1.381

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Aim To find out the relationship between inflammation and insulin resistance with impaired HDL biogenesis that cause low HDL-c concentrationMethods Using a cross-sectional design, this study involved 163 adult men, aged 25-60 years old with metabolic syndrome (IDF criteria, 2005), without liver and kidney dysfunction. This study was undertaken in Jakarta in the year 2007-2009. Measured indicators were serum apolipoprotein A-1 (apoA-1), prebeta-1 HDL, cholesteryl ester transfer protein (CETP), HDL cholesterol (HDL-c), body weight, height, waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), and triglyceride. The apoA-1/HDL-c ratios were taken as indicator of HDL maturation, whereas CETP/HDL-c and CETP/TG ratios were indicated HDL catabolism. high-sensitivity CRP (hsCRP) and HOMA-IR were taken as indicator of inflammation and insulin resistance, respectively. Data were analyzed by using univariate, bivariate, and multivariate analysis.Results Positive correlations were found between hsCRP and CETP (rs= 0.200, p= 0.042), and CETP/HDL-c ratios (rs= 0.188, p= 0.013). HOMA-IR positively correlated with apoA-1/HDL-c ratios (rs= 0.190, p= 0.016) and negatively correlated with the CETP/TG ratios (rs= -0.162, p= 0.04). Results of general linear model analysis showed that serum hsCRP concentration had the highest contribution to CETP/HDL-c ratios, apoA-1, dan CETP (p= 0.009; 0.016; 0.054, respectively).Conclusions Inflammation and insulin resistance related to dysfunction of HDL biogenesis in men with metabolic syndrome. The inflammation correlated with increased HDL catabolism, whereas the insulin resistance correlated with decreased HDL maturation and increased HDL catabolism. These may lead to low HDL-c concentration. Inflammation had higher contribution to HDL biogenesis factors than insulin resistance. (Med J Indones 2010; 19:36-45)Keywords: hsCRP, HOMA-IR, apoA-1, prebeta-1 HDL, CETP, HDL-c and metabolic syndrome
Development of Semiquantitative Food Frequency Questionnaire for Identification of Indigenous Dietary Patterns in Prediabetic Adult Women Nuryani, Nuryani; Khomsan, Ali; Dwiriani, Cesilia Meti; Dewi, Mira; Lukito, Widjaja
Media Gizi Indonesia Vol. 19 No. 1 (2024): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v19i1.28-39

Abstract

Dietary patterns influence the progression of prediabetes, so it is necessary to develop representative instruments for measuring eating habits, primarily indigenous dietary consumption. The research aimed to develop a semiquantitative food frequency questionnaire to identify indigenous dietary patterns in prediabetes sufferers in Gorontalo Regency. The research was a descriptive study that tested the validity and reliability of the food frequency questionnaire semiquantitative (FFQ-SQ). The research was conducted in Limboto Barat Health Center, based on the prevalence of diabetes mellitus. Selection samples using purposive sampling with 30 adult women. The validity test used internal validity Pearson correlation, while the reliability test used internal consistency Cronbach α. Comparison of average FFQ-SQ and recall 2 x 24-hours using Wilcoxon test. The results showed that 12 food groups consisted of 207 food items and indigenous food products with validity tests 123 items valid, 67 items invalid, and 17 items never consumed by the subject study in the previous month; the reliability test showed food group category low 10, moderate 5 and high 3. Comparative analysis of the energy and nutrient intake between FFQ-SQ with recall 2 x 24 hours showed significant differences in intake of carbohydrates, fiber, vitamin E, vitamin B1, folic acid, vitamin C, potassium and zinc (p-value < 0.005), and comparison of energy and nutrient intake between FFQ-SQ1 and FFQ-SQ2 showed no significant difference (p-value> 0.005). The conclusion was FFQ-SQ with 123 items of foods and derived products is valid and reliable for measuring the eating habits of prediabetic adult women.
Consumption of Sugar-Sweetened Beverages and Its Potential Health Implications in Indonesia Sartika, Ratu Ayu D; Atmarita, Atmarita; Duki, M. I Zulkarnain; Bardosono, Saptawati; Wibowo, Lindawati; Lukito, Widjaja
Kesmas Vol. 17, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The broad availability of sugar-sweetened beverages (SSBs) in the Indonesian market is increasing consumption. It, combined with escalating incidence and prevalence of diabetes and related non-communicable diseases (NCDs), and the ongoing debate on policies, has called for a comprehensive review as described in this study. Data was compiled from various sources but mainly gathered from the reported or published documents because of no direct access to the necessary data set. The lack of studies that assessed the direct relationship between SSB consumption and health outcomes in the Indonesian context also became a strong reason for the preparation of this review to highlight important points for further research, academic reviews, and debates on empiric policies to control sugar consumption at the population level. Sociocultural factors were an apparent and crucial determinant of the sweetness preferences of mainstream Indonesians. They were not capitalized in the available documents and should be embraced in future health promotional measures. Given the high contribution of carbohydrates and sugar to total energy intake in the Indonesian diet, it is pertinent to control the increasing trend of SSBs consumption through interventions on both the supply and demand sides.