Mahmiah Mahmiah
Laboratory of Chemistry, Hang Tuah University, Jl. Arif Rahman Hakim 150 Surabaya

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

Patterns of Physico-Chemical Interactions of Heavy Metal Lead (Pb) in the Jagir River Estuary System, Surabaya Prasita, Viv Djanat; Mahmiah, Mahmiah; Widagdo, Supriyatno
Indonesian Journal of Geography Vol 57, No 1 (2025): Indonesian Journal of Geography
Publisher : Faculty of Geography, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijg.99161

Abstract

The Jagir River estuary system constitutes a significant ecosystem in Surabaya that sustains the livelihoods of the surrounding communities. Despite its importance, the river is subjected to substantial pollution originating from domestic and industrial waste. Therefore, this study aims to investigate the patterns of physicochemical interactions between lead (Pb) in the Jagir River estuary system. Water and sediment samples were collected at 5 strategic points, and the concentration of Pb was analyzed using Inductively Coupled Plasma optical emission spectrometry (ICP-OES). The correlation between Pb and various environmental parameters (temperature, salinity, DO, pH & TDS) was analyzed using Principal Component Analysis (PCA). The results showed that the concentrations of Pb in the water column and sediment were 0.1637 – 1.8905 ppm and 0.0735 – 0.2349 ppm, respectively, exceeding the established quality standards for water. Pb content in the waterbody exhibited an increasing trend from upstream to the sea. These results show the salinity and tidal parameters as characteristic features of the Jagir River estuary system, which influence Pb content in water and sediment. The distinct characteristics of this estuary system vary for each region or location, showing that the results can contribute to the development of environmental policies and monitoring of water quality.Received: 2024-08-15 Revised: 2024-09-12 Accepted: 2025-01-25 Published: 2025-04-28 
SKRINING FITOKIMIA DAN UJI POTENSI ANTIKANKER EKSTRAK METANOL KULIT BATANG (Rhizophora mucronata (Lamk.)) MENGGUNAKAN METODE BSLT (Brine Shrimp Lethality Test) Asniyah, Asniyah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardani
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.101

Abstract

Cancer is one of the leading causes of death in the world. The main therapies for cancer include surgery, chemotherapy, radiotherapy. However, the use of chemotherapy drugs can cause side effects such as hair loss, bone marrow suppression, drug resistance. Based on these side effects, this study conducted research on natural ingredients as an alternative to cancer treatment. Rhizophora mucronata can be used as an anticancer, where people in coastal areas or around mangrove forests use mangroves as medicinal plants, and are believed to have minimal side effects so that they can be developed as traditional medicines. In this study, analysis of phytochemical screening and anticancer potential tests of methanol extract of Rhizophora mucronata stem bark was carried out from Pamurbaya, Surabaya, East Java. In this study, the BSLT (Brine Shrimp Lethality Test) method was used to test the anticancer potential with the LC50 (Letal Concentration) value as a parameter. The results of phytochemical screening of the methanol extract of Rhizophora mucronata stem bark contain tannins, saponins, alkaloids, steroids, flavonoids, anthraquinones and polyphenols and have anticancer potential with an LC50 value of 120.8656 ppm which falls into the toxic category.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK AKAR BAKAU HITAM (Rhizophora mucronata (Lamk.)) DENGAN METODE DPPH (2,2-diphenyl-1-picrylhydrazyl) Sulistiorini, Indah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardan
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.102

Abstract

Indonesia is a country that has a variety of marine ecosystems that have a lot of potential, one of which is mangroves. Rhizophora mucronata is a species in the mangrove ecosystem in Indonesia. Rhizophora mucronata or black mangroves are plants that contain various kinds of compounds. Antioxidants play an important role in the prevention of degenerative diseases. This research is motivated by the presence of carcinogenic dangers caused by consuming synthetic antioxidants at high doses synthetic antioxidants can function as prooxidants which can increase oxidative stress and damage body cells, so it wants to explore the natural antioxidant potential of Rhizophora mucronata. Rhizophora mucronata root was chosen in this study because no one has examined the potential of this plant that grows in the Pamurbaya area, Surabaya - East Java as an antioxidant. This study aims to determine the content of secondary metabolites and antioxidant activity of the root extract of Rhizophora mucronata. In this study, the antioxidant activity test used the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results showed that the antioxidant activity of the methanol extract of Rhizophora mucronata root had very weak antioxidant activity with an IC50 value of 2604.56 ppm. The antioxidant potential of the methanol extract of Rhizophora mucronata root has an IC value of 50 with a very weak antioxidant intensity