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Multidrug resistant tuberculosis risk factors in Makassar, Indonesia Burhan, Siti Latifah; Wahiduddin, Wahiduddin; Maria, Ida Leida; Bustan, M Nadjib; Saleh, Lalu Muhammad; Balqis, Balqis
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24753

Abstract

Multidrug resistant tuberculosis (MDR-TB) is a significant public health concern in Indonesia, resulting in substantial morbidity and mortality rates. This study aimed to quantify the impact of risk factors of MDR-TB. A case-control study was conducted at Makassar Community Lung Health Center (BBKPM) in Makassar City. A total of 132 respondents, 66 cases, and 66 controls have participated in the study. Data was analyzed using the Stata version 14 tool, odds ratio (OR), and multiple logistic regression. Multiple logistic regression analysis identified significant risk factors for the occurrence of MDR-TB include previous TB treatment (OR=8.46, 95% CI: 3.278-21.858), positive acid-fast bacilli (AFB) sputum (OR=6.40, 95% CI: 2.525-16.260), and adverse drug event (OR=3.45, 95% CI: 1.008-11.867). The probability of developing MDR-TB is 95.9% if there is previous TB treatment with cases of relapse/loss to follow-up/failed treatment, positive AFB sputum, and adverse drug event. The most dominant risk factor for the occurrence of MDR-TB is a previous TB treatment. We suggest that an efficient directly observed treatment shortcourse (DOTS) strategy, particularly in the management of adverse drug event, overseeing and supporting patients who have recovered from MDR-TB, involves the collaboration of MDR-TB healthcare professionals and patient supporters in the Yamali TB community, moving synergistically as an effort to MDR-TB control and prevention.
Risk Factors for the Incidence of Drug-Resistant Tuberculosis in the Labuang Baji Hospital: A Healthpreneur Perspective Rahmat, Afiyah Mahdiyah; Noor, Nur Nasry; Maria, Ida Leida; Davies, George
Aptisi Transactions On Technopreneurship (ATT) Vol 6 No 3 (2024): November
Publisher : Pandawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34306/att.v6i3.394

Abstract

Tuberculosis (TB) caused by Mycobacterium tuberculosis, remains a global health challenge, with drug-resistant TB (TB-RO) posing significant risks to control efforts. This study aims to identify risk factors associated with TB-RO among patients at Labuang Baji Makassar Hospital, Indonesia. Conducted from September to October 2023, this analytical case-control study utilized a quantitative approach. Data were collected from the Tuberculosis Information System (SITB) and hospital medical records, involving all TB-RO patients under treatment between 2022 and 2023. Total sampling yielded 105 cases, with analysis performed using univariate, bivariate, and multivariate methods. Results indicate that age (OR=2.509, CI 95%: 1.120–5.622; p=0.036), positive BTA sputum (OR=3.397, CI 95%: 1.630–7.082; p=0.001), and prior treatment history (OR=0.461, CI 95%: 0.254–0.837; p=0.016) are significant factors. Positive BTA sputum emerged as the dominant risk. Findings suggest that inadequate treatment adherence may contribute to TB-RO incidence. The study concludes that age and BTA phlegm are key risk factors, while a history of successful treatment is protective. Strengthening patient monitoring and ensuring treatment compliance are essential for mitigating TB-RO risk and improving outcomes.
Pemberdayaan Keluarga dalam Pendampingan Penanganan Luka Ulkus Diabetes Melitus Type 2 di Kelurahan Labuang Baji Kecamatan Mamajang Kota Makassar Maria, Ida Leida; Wahiduddin, Wahiduddin; Thaha, Ridwan M.; Firman, Firman
Poltekita: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v5i1.2841

Abstract

South Sulawesi is one of the provinces with the prevalence of diabetes mellitus which continues to increase by 23% in 2022. Labuang Baji sub-district of Makassar city is one of the sub-districts with the highest number of diabetes mellitus patients with wounds/ulcers. This community service is intended to provide education and support to families on how to treat diabetic ulcers. Assistance was given to families (30 people) through communication, information, motivation and education methods through counseling and questionnaires. Tests were given before and after the assistance, then data were analyzed using the McNemer and Wilcoxon tests. Family knowledge before assistance was (36.7%) with poor knowledge, (63.3%) with good knowledge. After the assistance, the family's knowledge increased to (96.7%) good knowledge with an average increase in pre-test and post-test scores of 2.7 times. Based on the T-test, the p-value (<0.05) was obtained. So it can be concluded that the assistance of handling Type 2 diabetes mellitus ulcers in Labuang Baji Village, Mamajang Subdistrict, Makassar has a significant impact on the participants.
Efek Samping Obat terhadap Kepatuhan Pengobatan Antiretroviral Orang dengan HIV/AIDS Latif, Fachri; Maria, Ida Leida; Syafar, Muhammad
Kesmas Vol. 9, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tingkat kepatuhan pengobatan antiretroviral di Indonesia sangat rendah, yaitu 40 - 70%, yang masih di bawah target nasional dengan tingkat kepatuhan 95%. Berbeda dengan rata-rata nasional, Puskesmas Jumpandang Baru justru memiliki tingkat kepatuhan pengobatan antiretroviral pasien HIV/AIDS di atas 95%. Penelitian ini bertujuan untuk menganalisis faktor yang paling berpengaruh terhadap kepatuhan pengobatan antiretroviral orang dengan HIV/AIDS (ODHA). Jenis penelitian bersifat observasional analitik dengan pendekatan potong lintang. Populasi penelitian adalah 121 ODHA yang aktif menjalani pengobatan antiretroviral di Puskesmas Jumpandang Baru yang dipilih dengan menggunakan teknik exhaustive sampling. Sampel dalam penelitian ini adalah 121 sampel. Penelitian dilakukan pada 22 April hingga 28 Juni 2014 di klinik Voluntary Counseling and Test Puskesmas Jumpandang Baru Makassar. Analisis data menggunakan uji kai kuadrat dan regresi logistik. Hasil uji kai kuadrat menunjukkan ada hubungan antara pengetahuan, persepsi, riwayat efek samping obat, dukungan keluarga dan teman, serta interaksi antara pasien dengan petugas layanan antiretroviral terhadap kepatuhan pengobatan antiretroviral ODHA. Analisis regresi logistik menunjukan bahwa pengetahuan yang baik, persepsi positif terhadap pengobatan, serta efek samping obat yang tidak dirasakan adalah faktor yang berhubungan dengan kepatuhan pengobatan antiretroviral. Penelitian ini menunjukkan ODHA yang tidak merasakan efek samping obat memiliki kecenderungan terbesar untuk patuh terhadap pengobatan antiretroviral dengan OR sebesar 13,452. The rate of adherence to antiretroviral treatment in Indonesia is very low, at 40 - 70%, which is still below our national target (95%). Different phenomena happens at Jumpandang Baru Primary Health Care, whose level of antiretroviral treatment adherence above 95%. This study aimed to analyze factors that influence the adherence to antiretroviral treatment of people li- Efek Samping Obat terhadap Kepatuhan Pengobatan Antiretroviral Orang dengan HIV/AIDS Drug Side Effects on Adherence to Antiretroviral Treatment among People Living with HIV/AIDS Fachri Latif, Ida Leida Maria, Muhammad Syafar ving with HIV/AIDS (PLWH). This study used observational analytic with cross-sectional approach. The population, 121 PLWH are people who actively undergoing antiretroviral treatment in Jumpandang Baru Primary Health Care. By exhaustive sampling technique, the sample size of the study was counted 121 people. The research was conducted on April 22 until June 28 2014 at Voluntary Counseling and Test Clinic of Jumpandang Baru Primary Health Care, Makassar. Data was analyzed using chi square and logistic regression test. Chi square test showed the relationship between knowledge, perception, drug side effects, family and friends support, and well interaction between PLWH with antiretroviral providers to antiretroviral treatment adherence among PLWH. The logistic regression analysis indicated that high level of knowledge, positive perceived to treatment, and no drug’s side effects were the related factors influenced antiretroviral adherence. This result showed that PLWH who do not feel the drug side effects has the greatest propensity to adherence to antiretroviral treatment with an OR of 13.452.