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All Journal Journal of Agromedicine and Medical Sciences MEDICINUS Jurnal Pendidikan Terapan West Science Social and Humanities Studies Feedback International Journal of Communication International Journal of Health and Medicine
Dito Anurogo
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Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Bioinformatics Approach towards Transcriptomics of Filaggrin Dito Anurogo; Arli Aditya Parikesit
Journal of Agromedicine and Medical Sciences Vol 2 No 3 (2016)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Filaggrin, or filaments which combines protein, is one of the important structural protein that works for the development, maintenance, and the formation of the skin as an intact barrier. Filaggrin breakdown products regulate the hydration of the skin; contribute to the acidic pH of the skin, which in turn is essential for the activity of various proteases in the stratum corneum desquamation and lipid synthesis. Filaggrin produced by keratinocytes granular as a major precursor called profilaggrin, encoded by the FLG gene, located in the epidermal differentiation complex on chromosome 1 (1q21 locus). The locus contains a group of genes involved in epidermal differentiation. Filaggrin deficiency has some consequences on the organization and function of epidermal with important implications such as increased risk for atopic disease or a microbial infection. FLG mutation, a gene that encodes filaggrin, has been shown to cause ichthyosis vulgaris, increasing the risk of atopic dermatitis and other atopic diseases. This research examined the FLG gene based bioinformatics approach to search for conserved region of representative mammals that encode coding (m) and non-coding (nc) RNAs. Expected mRNA expression can be used as a diagnostic and therapeutic agent against deficiencies and filaggrin mutations.Key words: filaggrin, FLG, profilaggrin, filaggrin deficiency, bioinformatics.
Pendekatan Multiperspektif dalam Manajemen Penyakit Asma Dito Anurogo
MEDICINUS Vol. 35 No. 3 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/medicinus.v35i3.108

Abstract

Asthma is a chronic inflammatory disorder of the respiratory tract. This scientific review aims to provide comprehensive explanation about asthma, including epidemiology, etiology, diet and nutrition, genetic and epigenetic factor, pathophysiology, asthma control evaluation, imaging, management, and trend toward novel therapy in the future, such as nanotechnology.
Terapi Sel Punca dan Tata Laksana Covid-19 Dito Anurogo; Zahradiva Putu Fitria Hermawan; Nur Rahmah Awaliah; Taruna Ikrar
MEDICINUS Vol. 36 No. 1 (2023): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/medicinus.v36i1.113

Abstract

Covid-19 was first identified in Wuhan, China, and known as a disease that can damage the lungs, as well as other organs and system organs such as the heart and the immune system. To date, there is no specific treatment for this disease, however, scientists in China have conducted many clinical studies of cell-based therapies for patients with Covid-19 and other respiratory diseases, especially mesenchymal stem (stromal) cells (MSC), by utilizing MSC-derived conditioned media (CM) or extracellular vesicles and several other cell types. Recent preclinical data from respiratory viral infection models and clinical studies related to the use of MSCs by altering the expression of proinflammatory cytokines, and facilitate the repair of damaged tissue in Covid-19 patients. This research method uses descriptive case study method. The purpose of this study was to determine the effectiveness of therapy using stem cells or mesenchymal stem cells (MSCs) in the management of Covid-19. The results suggest that administration of allogeneic MSCs could accelerate the process of tissue repair in the lungs, thus reducing the need for further mesenchymal cell activation. Positive responses in subjects receiving UC-MSC treatment indicated a decrease in inflammatory cytokines, rather than a change in viral load. The high cost of cell therapy makes researchers only able to conduct limited clinical studies on cell therapy for Covid-19 patients.
Potensi farmakologi Kasumba Turatea (Carthamus tinctorius L.) sebagai antibakteri Lismayana Hansur; Ami Febriza; Dito Anurogo; Dara Ugi Aras; Endah Dwijayanti
MEDICINUS Vol. 37 No. 2 (2024): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/6zstjd88

Abstract

Kasumba turatea (Carthamus tinctorius L.) is a plant that has been used as traditional medicine in South Sulawesi. Themain component of C. tinctorius L. flowers is hydroxysafflor yellow A, which functions as an anti-inflammatory, antioxidant,and platelet aggregation inhibitor. This review highlights pharmacological potential of C. tinctorius L. as an antibacterialagent. The method involves a literature review from various databases such as PubMed, Google Scholar, and Scopus. Theresults show that C. tinctorius L. extracts are effective against various pathogenic bacteria such as Listeria monocytogenes,Streptococcus iniae, Staphylococcus aureus, and Escherichia coli. Bioactive compounds like carthamin, phenolics, and flavonoids exhibit significant antibacterial activity. Additionally, C. tinctorius L. extracts also show potential as anthelminticand antioxidant agents. Further research is required to isolate and characterize specific bioactive compounds, followed by in vivo validation and clinical study to confirm their efficacy as well as safety. 
Analisis Penerapan Media Gamifikasi Psikiatri dalam Model Hybrid Learning Dito Anurogo; Andika Isma; Nur Yahya Akhmad; Ainun Fadillah Agus; Andi Ahmad Jalal Syamsir
Jurnal Pendidikan Terapan Vol 2, No 1 January (2024)
Publisher : Sakura Digital Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61255/jupiter.v2i1.212

Abstract

Penelitian ini menyelidiki respons mahasiswa terhadap penerapan gamifikasi dalam pembelajaran psikiatri di lingkungan perguruan tinggi. Dengan menggunakan metode kuantitatif dan rancangan penelitian cross-sectional, data dikumpulkan melalui kuisioner dari 60 mahasiswa jurusan Teknik Informatika dan Komputer di Universitas Negeri Makassar. Dimensi evaluasi mencakup kegunaan, kemudahan penggunaan, sikap, dukungan sosial, dan keterlibatan dalam pendidikan melalui gamifikasi. Hasil analisis data deskriptif mengungkapkan tingkat setuju yang tinggi terhadap penggunaan gamifikasi, dengan rata-rata yang relatif tinggi untuk setiap dimensi. Dalam aspek kegunaan, mahasiswa menyatakan bahwa gamifikasi secara positif memengaruhi kinerja belajar dan motivasi mereka. Selain itu, aspek kemudahan penggunaan menunjukkan persepsi positif terkait fleksibilitas dan kejelasan sistem gamifikasi. Aspek sikap mencerminkan dukungan terhadap penggunaan gamifikasi dalam pembelajaran. Aspek dukungan sosial dan keterlibatan dalam pendidikan juga menunjukkan respons positif, menyoroti peran gamifikasi dalam meningkatkan interaksi dan partisipasi mahasiswa di dalam kelas.
Da'wah Communication Strategies in Dealing with Online Gambling among Teenagers Novianto Puji Rahardjo; M. Nashoihul Ibad; Dito Anurogo
Feedback International Journal of Communication Vol. 1 No. 3 (2024): September 2024
Publisher : PT Agung Media Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62569/fijc.v1i3.48

Abstract

Online gambling has become a serious problem that threatens the younger generation, especially teenagers. "Online gambling has serious psychological impacts, such as stress, depression, and social isolation, and has the potential to trigger criminal acts. Online gambling addiction can damage many aspects of a teen's life, including mental health, social relationships, academic achievement, and financial stability. This research aims to formulate an effective da'wah communication strategy to overcome these problems. This qualitative research is carried out using a case study approach. The results of the study show that a combination of personal, community, and social media approaches is an effective da'wah communication strategy in dealing with online gambling among teenagers. An individual approach through counseling and mentoring can provide emotional and spiritual support to adolescents who are involved in online gambling. The community approach consists of working with religious leaders, community leaders, and educational institutions to create an environment that supports a healthy lifestyle and is free from gambling. Meanwhile, the social media approach can be used to spread positive messages and anti-gambling campaigns more widely. In addition, this research also enriches the understanding of the importance of integration between traditional and modern communication in the context of da'wah. Keywords:  Communication Strategies, Da'wah Communication, Online Gambling, Teenagers  
Next-Gen Global Health 6.0: Integrative Genomics, Nano-Immunotherapies, and AI for Infectious and Chronic Disease Convergence Dito Anurogo
International Journal of Health and Medicine Vol. 2 No. 1 (2025): January : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v2i1.126

Abstract

The Next-Gen Global Health 6.0 initiative offers an integrative model employing genomics, nano-immunotherapies, and artificial intelligence (AI) to address the escalating complexity of global health issues, particularly the convergence of infectious and chronic diseases. This framework advances precision medicine by integrating real-time genomic surveillance with AI algorithms, enabling timely prediction and response to outbreaks, as well as tailored therapeutic approaches. Nano-immunotherapies play a critical role in modulating immune responses with high specificity, especially in chronic infections and diseases resistant to conventional treatments. Through these synergistic technologies, the Next-Gen Global Health 6.0 approach aims to transcend traditional healthcare boundaries, offering scalable, data-driven interventions that are adaptable to varying resource levels worldwide. Emphasizing accessibility and equity, this framework highlights the necessity for innovative health policies and interdisciplinary collaboration to optimize deployment in underserved regions, ultimately contributing to sustainable, resilient healthcare systems prepared for evolving global health challenges.
Mapping Studies on Risk and Protective Factors for Mental Health in the Modern Era Dito Anurogo; Yuanti, Yocki; Kubillawati , Sri; Suprayitno, Emdat; Abdullah, Gamar
West Science Social and Humanities Studies Vol. 2 No. 01 (2024): West Science Social and Humanities Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsshs.v2i01.621

Abstract

This bibliometric study delves into the extensive literature on risk and protective factors for mental health in the modern era, considering the complexities posed by technological advancements, socio-cultural shifts, and globalization. Utilizing bibliometric analysis, we identify clusters of literature, analyze trends over time, and explore potential research avenues. The network visualization reveals six distinct clusters, each representing thematic discussions related to mental health. Trend analysis highlights the evolution of research focus from early concerns to contemporary issues, with COVID-19 emerging as a prominent theme. Density analysis identifies research gaps and potential future topics. The collaboration network among authors suggests opportunities for interdisciplinary research. This analysis offers valuable insights for researchers, policymakers, and practitioners to inform evidence-based strategies for navigating the intricate landscape of mental health in the modern era.
Co-Authors Ainun Fadillah Agus Ami Febriza Andi Ahmad Jalal Syamsir Andika Isma Arli Aditya Parikesit Dara Ugi Aras Emdat Suprayitno Endah Dwijayanti Gamar Abdullah Kubillawati , Sri Lismayana hansur M. Nashoihul Ibad Novianto Puji Rahardjo Nur Rahmah Awaliah Nur Yahya Akhmad Taruna Ikrar Yuanti, Yocki Zahradiva Putu Fitria Hermawan