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All Journal Jurnal Sains dan Pendidikan Fisika Kodifikasia: Jurnal Penelitian Islam JFIOnline Jurnal Ilmiah Kesehatan Diagnosis LAN TABUR: Jurnal Ekonomi Syari’ah Al-Syakhsiyyah : Journal of Law and Family Studies Pharmaceutical Sciences and Research (PSR)
Abdul Munim
Fakultas Farmasi, Universitas Indonesia
Religion Humanities Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Pengembangan Metode Induksi Tukak Lambung Saputri, Fadlina Chany; Sari, Santi Purna; Munim, Abdul
Majalah Ilmu Kefarmasian Vol. 5, No. 2
Publisher : UI Scholars Hub

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Abstract

Scientific evaluation on pharmacological activity of medicinal herbs required repro-ducible and valid method-induced ulcer models in animal. In this study, the method of antiulcerogenic effect was investigated using several inducers. The male white Sprague-Dawley rats divided into five groups which were orally administrated water, indomethacin (48 mg/kg bw), aspirin-HCl (150 mg/kg bw), 96% ethanol (1 ml/200 g bw), and 80% ethanol (1 ml/200 g bw), respectively. The result of this study showed that the group was induced with 80% ethanol demonstrated the highest ulcer index. Histological examination of the stomach showed abnormality of mucosa cells on the aspirin-HCl, 96% ethanol, and 80% ethanol-induced gastric ulcer model in rats.
Karakterisasi Ekstrak Etanolik Daun Asam Jawa (Tamarindus indica L.) Munim, Abdul; Hanani, Endang; Rahmadiah, Rahmadiah
Majalah Ilmu Kefarmasian Vol. 6, No. 1
Publisher : UI Scholars Hub

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Abstract

Leaves of tamarind (Tamarindus indica L.) has been traditionally used to treat some diseases such as: constipation, dyspepsia, flatulence and urinary tract infection. The leaves extract also reported has antibacterial and antidiabetic activities. It is essential to determine its specific and non specific parameters in assesing the quality and safety. The samples collected from three different perferctures. Grounded samples were macerated with ethanol. The extracts were subjected to determine its characteristic parameters. Parameter of quality for the extracts consisted of water content, ethanol-extractive, water-extractive, loss on drying, total ash, acid-insoluble ash, solvent residue and heavy metal content. Phytochemical identification showed that the ex-tract contains flanovoid, tannin, glycosides, and saponin. TLC chromatogram using chloroform-methanol-water (80:12:2) as mobile phase, exhibited 4 spots after sprayed with iron(III) chloride. Total phenolic was determined pectrophotometrically using Folin Ciocalteu reagent, gave 0.35-8.24% total phenolic as gallic acid.
Skrining Fitokimia dan Uji Penghambatan Aktivitas alfa-glukosidase pada Ekstrak Etanol dari Beberapa Tanaman yang Digunakan sebagai Obat Antidiabetes Munim, Abdul; Azizahwati, Azizahwati; Andriani, Ayu
Majalah Ilmu Kefarmasian Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglicemia and associated with abnormalities in carbohydrate, fat, and protein metabolisms. Patients with DM in the world continue to increase along with population growths. Starting from this condition, searching for sources of DM treatment is always performed. One therapy of DM is a-glucosidase inhibitor. a-Glucosidase is an enzyme that can break down a complex carbohydrate into simple sugar. lhe inhibiton of this enzyme can retard the rate of carbohydrate digestion resulting in a delay in glucose absorption. The purpose of this studywas to identify the content of chemical compound and to test the a-glucosidase inhibitory activity in ethanolic extracts of some plants used as antidiabetic. a-Glucosidase inhibitory activity test carried out by spectrophotometric method. The simplisia powder was extracted by reflux using 80% ethanol. Based on a-glucosidase inhibitory activity test, all the plant extracts were active in inhibiting a-glucosidase. lhe three most active extracts were Ceiba pentandra (L.) Gaetern bark extract, Saccharum offcinarum root extract, and Persea americana Mill. bark extract with IC50 of 5.16, 10.35 and 10.83 ppm, respectively. They contain glycoside, tannin, and saponin. The test results of the kinetics enzyme inhibition showed that Randu bark extract had competitive inhibitory activity.
Pengaruh Pemberian Sari Buah Mengkudu (Morinda citrifolia Linn.) Terhadap Glibenklamid dalam Menurunkan Kadar Glukosa Darah Tikus Putih Jantan yang Dibuat Diabetes Sari, Santi Purna; Munim, Abdul; Fitriani, Sri Wulandah
Majalah Ilmu Kefarmasian Vol. 9, No. 1
Publisher : UI Scholars Hub

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Drug interactions can occur in the use of two or more drugs simultaneously, including the use of synthetic drug with herbal medicine. Combination of glibenclamide with noni juice (Morinda citrifolia Linn.) often used by diabetic patient to decrease their blood glucose level. lhe aim of this research was to know the interaction between glibenclamide and noni juice administration on blood glucose level. This research used 24 Sprague-Dawley male rats which were divided into 6 groups. Before the experiment, the rats were first induced by alloxan, except group 1, which was the normal control. Group 2 was the control of diabetic without given any drugs. Group 3 and 4 were the control of glibenclamide (0.9 mg/200g body weight of rat) and of noni juice (2.5 ml/200g body weight of rat) respectively. Group 5 and 6 were the interaction test group which were given glibenclamide (0.9 mg/ 200 g body weight rat) and noni juice (2.5 ml or 5.0 ml/200 g body weight of rat) with an hour interval. The blood glucose level was measured by using spectrophotometer with o-toluidine as reagent. The result of this research shows that noni juice at a dose 5.0 ml/200 g body weight rat was able to increased the reduction of blood glucose levels by glibenclamide after two weeks administration
AKAR MODERASI BERAGAMA DALAM KITAB AL-RISALAH IMAM SYAFI’I munim, abdul; Tanzilulloh, M. Ilham
Al-Syakhsiyyah: Journal of Law & Family Studies Vol. 3 No. 1 (2021)
Publisher : Fakultas Syariah IAIN Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/syakhsiyyah.v3i1.8683

Abstract

This research aims to analyze how the scholarly challenges in composing Ar-Risalah, to understand Ar-Risalah's criticism of extremism in diversity at that time, and to identify offers from Ar-Risalah that can be identified as moderation. This study uses qualitative research methods, with a philosophical approach. The primary data source is the book Ar-Risālah by Muhammad bin Idris ash-Shafi'i, also known as Imam Shafi'i, edited by Ahmad Muhammad Syakir. The findings of this research indicate that at the time of the legal discourse tension between the opposing factions, usul (fundamentals) had not yet emerged as a discipline because its epistemological framework was unclear. Al-Risalah begins with an exposition on the epistemological aspects of Islamic law. The legal methodological concept offered by ash-Shafi'i aims to control excessive rationality that demands change and excessive textualism that demands certainty toward a moderate position, as written in the book Ar-Risalah.
Strategi Pemasaran UMKM Konveksi Hijab di Pondok Pesantren Addimyati Desa Pondok Lalang Kecamatan Jenggawah Kabupaten Jember 2021 Munim, Abdul; Hayati, Putri Nur
LAN TABUR : Jurnal Ekonomi Syariah Vol. 3 No. 2 (2022): Maret
Publisher : Lembaga Pusat Penelitian dan Pengabdian kepada Masyarakat (LP2M) Institut Agama Islam (IAI) Al-Qodiri Jember, Jawa Timur Indonesia bekerjasama dengan Kopertais Wilayah 4 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53515/lantabur.2022.3.2.166-179

Abstract

Tujuan dalam penelitian adalah: 1) Untuk mendeskripsikan strategi pemasaran UMKM Konveksi Hijab dipondok pesantren Addimyati desa pondok lalang Kec. Jenggawah Kab. Jember. 2) Untuk Mendeskripsikan kendala-kendala yang dihadapi Umkm konveksi Hijab di pondok pesantren Addimyati desa pondok lalang Kec. Jenggawah Kab. Jember. Dalam penelitian ini peneliti menggunakan pendekatan kualitatif deskriptif, jenis penelitiannya menggunakan penelitian lapangan (field research). Hasil penelitian menyimpulkan bahwa: 1) strategi pemasaran Umkm Konveksi Hijab ini menggunakan bauran pemasaran (marketing Mix) diantaranya: strategi produk, UMKM Konveksi Hijab ini sangat menjaga kualitas produk yang dijahit serta produk yang dihasilkan ini termasuk barang tahan lama (durable goods). Strategi harga, dalam menetapkan harga Umkm Konveksi hijab ini menghitung HPP kemudian ditambah beberapa persen berdasarkan lama waktu pengerjaan beserta cepat atau lambatnya perputaran barang. Strategi promosi yakni offline dan online dengan cara kontal langsung dengan konsumen (personal selling) dan online melalui media sosial seperti fb, instagram, shoppe, Wa, lazadah. Strategi Distribusi, dalam mendistribusikan produk Umkm Konveksi hijab menggunakan distrubusi secara langsung dan tidak langsung. Secara langsung dengan mendatangi toko sedangkan tidak langsung melalui resseller.
Strategi Pemasaran UMKM Batik daam Menghadapi Pemasaran Global (Studi Kasus di Mizya Batik Tulis Ledokombo Jember) Munim, Abdul; Roif, Moch.
LAN TABUR : Jurnal Ekonomi Syariah Vol. 4 No. 2 (2023): Maret
Publisher : Lembaga Pusat Penelitian dan Pengabdian kepada Masyarakat (LP2M) Institut Agama Islam (IAI) Al-Qodiri Jember, Jawa Timur Indonesia bekerjasama dengan Kopertais Wilayah 4 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53515/lantabur.2023.4.2.191-203

Abstract

Tujuan penelitian ini adalah: 1) Untuk mendeskripsikan bagaimana strategi pemasaran yang di lakukan oleh mizya batik tulis di desa slateng kecamatan ledokomo kabupaten jember, 2) Untuk mengetahui apa saja kendala permasalahan UMKM mizya batik tulis dalam melakukan pemasaran, 3) Bagaimana alternatif strategi pemasaran yang efektif dalam meningkatkan jumlah penjualan di UMKM mizya batik tulis di desa slateng kecamatan ledokombo kabupaten jember Dalam penelitian ini peneliti menggunakan pendekatan kualitatif deskriptif, jenis penelitiannya menggunakan penelitian lapangan (field research). Hasil dari penelitian ini adalah: 1) strategi pemasaran UMKM mizya batik tulis di desa slateng kecamatan ledokombo kabupaten jember yang menngunakan bauran pemasaran (marketing mix) yang meliputi : Strategi produk, Strategi harga, Strategi promosi, dan Strategi distribusi,. 2) kedala apa saja permasalahan UMKM mizya batik tulis dalam melakukan pemasaran yang meliputi tentang: harga dan persaingan pasar. 3) Bagaimana alternatif strategi pemasaran yang efektif dalam meningkatkan jumlah penjualan di umkm mizya batik tulis, yaitu dengan bekerja sama dengan berbagai pihak seperti tanoker dan jalan ini di lakukan untuk memperlancar pemasaran dan meningkatkan jumlah penjualan.
PENGARUH PEMBERIAN TEPUNG DAUN KELOR (Moringa oleifera) TERHADAP PENURUNAN GLUKOSA DARAH PADA PENDERITA PRADIABETES DI WILAYAH KERJA PUSKESMAS SAMATA KAB.GOWA Munim, Abdul; Alwi, Muh. Khidri; Syam, Aminuddin
Diagnosis Jurnal Ilmiah Kesehatan Vol. 13 No. 6 (2019): Diagnosis: Jurnal Ilmiah Kesehatan
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Pradiabetes telah menjadi pandemi dengan prevalensi lebih tinggi dari diabetes, pradiabetes meningkat lebih tinggi karena menyerupai fenomena gunung es, jumlah individu yang belum terdeteksi DMT2 lebih banyak dibanding DMT2. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian tepung daun kelor terhadap penurunan glukosa darah pada penderita penyakit prediabetes. Penelitian ini merupakan quasy eksperimen dengan pre-post tes control design. Populasi penelitian adalah masyarakat yang mengalami prediabetes di Desa Samata Kab. Gowa. Besar sampel 20 pradiabetes dibagi menjadi kelompok intervensi 10 dan kontrol 10. Kelompok intervensi diberikan tepung daun kelor selama 25 hari dosis 2X1 1000 (mg/hari ), kelompok kontrol diberikan edukasi pencegahan diabetes. Data dianalisis menggunakan uji Paired Samples Test dan uji independent Samples Test. Hasil penelitian pada pengukuran GDP kelompok intervensi sebelum perlakuan dan setelah perlakuan memiliki nilai p = 0,000, dengan nilai selisih -20,2 maka dikatakan bahwa ada perbedaan signifikan antara glukosa darah puasa sebelum perlakuan dan sesudah perlakuan pada kelompok perlakuan dan pada kelompok kontrol sebelum dan setelah perlakuan memiliki nilai p=0,420 dengan nilai selisih -2,3 maka dikatakan tidak ada perbedaan yang signifikan antara GDP sebelum dan setelah perlakuan. Disimpulkan bahwa ada perbedaan kadar glukosa darah pada penderita prediabetes sebelum dan setelah pemberian tepung daun kelor pada kelompok intervensi di Wilayah Kerja Puskesmas Samata Kab. Gowa. Diharapkan pradiabetes rutin mengkonsumsi tepung daun kelor agar terhindar dari diabetes melitus.
Co-Authors . Andriansjah . Azizahwati Alwi, Muh. Khidri Aminuddin Syam Andita Mandasari Andita Mandasari, Andita Anggraeni, Yosita Anggraeni, Yosita Ayu Andriani, Ayu Ayu Fimani Dini Hariria, Dini Effionora Anwar Endang Hanani Endang Hanani Fadlina Chany Saputri Hayati, Putri Nur Hayun Hayun, Hayun Heni Susilowati Hidayati, Niswatul Joshita Djajadisastra, Joshita Lukman Santoso Mahdi Jufri MARIA BINTANG Maria Tuntun Octaviarini Hidayah, Octaviarini Raditya Iswandana Rahmadiah, Rahmadiah Retnosari Andrajati Roif, Moch. Santi Purna Sari Santi Purna Sari Sappewali, Sappewali Sri Wulandah Fitriani, Sri Wulandah Tanzilulloh, M. Ilham Ulfah Aunillah, Ulfah Wahyuni, Ayusari Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yohanna Aristanti