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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Majalah Kedokteran Bandung e-Journal Pustaka Kesehatan Journal of Agromedicine and Medical Sciences Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Ilmiah Kesehatan Jember Medical Journal (JMJ)
M. Ihwan Narwanto
Fakultas Kedokteran Universitas Jember
Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Public Health

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Journal : e-Journal Pustaka Kesehatan

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Efek Pemberian Vitamin E (d-α-tocopherol) terhadap Memori Kerja Spasial Tikus (Rattus novergicus) Remaja yang Diinduksi Etanol Shera Nadhila Setyo Bisono; M. Ihwan Narwanto; Kristianningrum Dian Sofiana
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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During neurogenesis process, nerve cells especially hippocampus susceptible to damage when exposed to ethanol. Vitamin E is an antioxidant and capable to protect nerve cells damage. This study aimed to determine the effect of vitamin E (d-α-tocopherol) on spatial working memory of adolescent rats induced with ethanol. The study used 30 days-old rats (Rattus novergicus), weight between 50-100 grams. Total of 25 rats were divided into 5 groups: 2 control groups and 3 treatment groups. K1/K(-) was normal group without ethanol and vitamin E, and K2/K(+) were induced with ethanol. The treatment groups were given ethanol and vitamin E at a dose of 100mg/kgBW; 200 mg/kgBW; 400 mg/kgBBW respectively for P1, P2 and P3. After treatment for 14 days, the rats were tested for spatial working memory using the Radial Arm Maze (RAM) for 10 consecutive days. Spatial working memory was observed by the total number of right arm option which were entered by rats. The average number of right arm maze option for 10 days, were; K (-): (7 ± 0.52), K (+): (3.98 ± 0.66), P1: (4 , 56 ± 0.41), P2: (6.76 ± 1.01) and P3 (6.38 ± 0.63). In conclusion, there was an effect of vitamin E at a dose of 200 mg/kgBW and 400 mg KgBW on spatial working memory of ethanol-induced adolescent rats.   Keywords: ethanol, vitamin E, spatial memory, Radial Arm Maze
Pengaruh Minuman Kopi Minim Kafein terhadap VO2max dan Pemulihan Denyut Nadi setelah Melakukan Treadmill (The Effect of Decaffeinated Coffee Drink on VO2max and Pulse Recovery Rate after Treadmill Test) Chikita R Hanifati; Cholis Abrori; M Ihwan Narwanto
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Coffee can be classified as a psicostimulant agent cause awakening, due to its content, such as caffeine. For intolerant person caffeine can be harmful, so nowadays created decaffeinated coffee. The purpose of this study was to determine the effect of decaffeinated coffee drink consumption on VO2max and pulse recovery rate after treadmill test. This was a quasi experimental study with Randomized Clinical Trial (RCT) methods. There were 20 volunteers, divided into two groups that swapping roles after 4 days washing out. The control group was given an instant coffee drink while the treatment group was given a decaffeinated coffee drink. All volunteers were asked to perform Modified Bruce Treadmill Test procedure until exhausted then VO2max were examined. The results showed the average value of VO2max in treatment group was +45,22 ml/kg/min and in control group +46,96 ml/kg/min from the previous study the value of VO2max using placebo was 25,98 ml/kg/min. Duration of pulse recovery rate in treatment group was 52 minutes faster than control group, 57 minutes. Analyses by T-test obtained p=0,23 mean there was no significant difference. In conclusion, decaffeinated coffee drinks could increased VO2max as the instant coffee did, but it still could accelerate pulse recovery rate. Keywords: Modified Bruce Treadmill, pulse recovery rate, VO2max, decaffeinated coffee
Pengaruh Minuman Kopi terhadap VO2max dan Pemulihan Denyut Nadi pasca Melakukan Treadmill (The Influence of a Coffee Drinks to VO2max and Pulse Recovery after Doing Treadmill) Natasha Amelia; Cholis Abrori; M Ihwan Narwanto
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Coffee can be classified as a psicostimulant which cause person stay awake. Coffee contains any ingredients such as caffeine.Caffeine could improve the performance of athletes. VO2max is a highest ratio of oxygen consumed during intense physical activity. The purpose of this study was to determine the effect of caffeine consumption on VO2max and exercise recovery pulse. The study used experimental research with Randomized Clinical Trial (RCT) methods. There were 20 volunteers, who were divided into two groups. The control group was given a drink that contains no caffeine while the treatment group was given a drink containing caffeine. Then all volunteers were asked to perform Modified Bruce Treadmill Test procedure until exhaustion occurred then VO2max.The next 4 days were washing out period where the control and treatment groups swap the roles. The results showed the average value of VO2max in the treatment group was 30.69 ml/ kg/min higher than in the control group 25.98 ml/ kg/min, but the duration of pulse recovery in the treatment group was 127 minutes slower than the control group, 121 minutes, indicating to its effects as a stimulant. In conclusion, administration of caffeine increased VO2max, but delayed time of pulse recovery.   Keywords: Modified Bruce Treadmill Test, pulse recovery, caffeine,VO2max
Efek Ekstrak Teh Hijau (Camellia sinensis) terhadap Memori Kerja Spasial Tikus Wistar (Rattus novergicus) Remaja yang Diinduksi Etanol Prasetia Aji Ramadhan; Muhamad Ihwan Narwanto; K Dian Sofiana
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Ethanol is a well-known agent causing organ damage including hippocampus. Hippocampus damage will reduce spatial memory. This study aimed to determine the effects of green tea extract on spatial memory function in adolescent rats following ethanol administration. One of cathecin derivates in green tea is EGCG which is believed to prevent hippocampal damage due to ethanol. The research was conducted on 25 rats, divided into 5 groups with 2 control groups and 3 experimental groups. A control group 1 (K1) was given 20 % ethanol with a dose of 2g/kgBW, while a control group 2 (K2) was only given with distilled water. All experimental groups (P1,P2 and P3) were given ethanol 2gr/kgBW and green tea extract with a dose of 108mg/200gBW, 216mg/200gBW, and 432mg/200gBW, respectively for P1, P2, and P3. Administration of ethanol and green tea extracts were performed for 14 days. The rats' spatial memory were tested by observation using the Radial Arm Maze ( RAM ) for 10 days. The number of the right arm in K1 was fewer than K2, P1, P2 and P3, but in K2 the right arm similar with P2 and higher than P1 and P2. In conclusion, the green tea extract influence the spatial memory of ethanol-induced adolescent rat. Keywords: Ethanol, green tea extract, Radial Arm Maze, spatial memory
Co-Authors Azham Purwandhono Chikita R Hanifati Cholis Abrori, Cholis Desie Dwi Wisudanti Elvia Rahmi Marga putri Ida Srisurani Wiji Astuti Irwanda, Thalita Permata Padhantya Jauhani, Muhammad Afiful K Dian Sofiana Kristianningrum Dian Sofiana Kristianningrum Sofiana Kusumastuti, Inke Masruroh Rahayu Masruroh Rahayu, Masruroh Moch. Aris Widodo Muhammad Afiful Jauhani Muhammad Haikal Supriyadi Natasha Amelia Nita, Surya Novan Krisno Adji Nurdiana Nurdiana Nurdiana Nurdiana Pipiet Wulandari Pranika, Hafidh Restu Prasetia Aji Ramadhan Putri, Elvia Rahmi Marga Putri, Komang Yunita Wiryaning Setyawati Soeharto Setyawati Soeharto, Setyawati Shera Nadhila Setyo Bisono Siti Jamalia Syadza Salsabila Yuli Hermansyah Yuli Hermansyah Zahrah Febianti Zahrah Febianti