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All Journal Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Kesehatan Amanah
Maya Ganda Ratna
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Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Korelasi antara Monocyte Lymphocyte Ratio dengan Stadium Pasien Chronic Kidney Disease Non Hemodialisis di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2023-2024 Ade Yonata; Dafa Rafiqi Akbar; Maya Ganda Ratna
Jurnal Kesehatan Amanah Vol. 8 No. 2 (2024): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v8i2.666

Abstract

Chronic kidney disease (CKD) is a serious condition accompanied by various comorbidities, systemic inflammation, and kidney tissue damage, leading to a decline in the glomerular filtration rate (GFR), which determines CKD staging. The monocyte-lymphocyte ratio (MLR) can serve as a more practical alternative that does not increase laboratory examination costs and utilizes a complete blood count, a routine hospital test. Several studies have reported that MLR values are associated with clinical deterioration and inflammation in CKD patients. This study aims to determine the correlation between MLR and CKD stage in non-hemodialysis patients at Dr. H. Abdul Moeloek Regional General Hospital, Lampung. This study is an analytical observational study using a cross-sectional method involving all non-hemodialysis CKD patients who met the inclusion and exclusion criteria at Dr. H. Abdul Moeloek Regional General Hospital. The sampling technique used was total sampling, with a total of 346 non-hemodialysis CKD patients collected from medical records between July 2023 and June 2024. Data analysis was performed using the Spearman alternative test. Based on the study of 346 patients, bivariate analysis showed a significant correlation between MLR and CKD stage (p = 0.000; r = 0.444). There is a significant positive correlation of moderate strength between MLR and CKD stage in non-hemodialysis patients at Dr. H. Abdul Moeloek Regional General Hospital, Lampung.
Perbandingan Ceftriaxone dan Ciprofloxacin dalam Tata Laksana Infeksi Saluran Kemih: Tinjauan Pustaka Maya Ganda Ratna; Sinta Nurmalasari; Meta Tri Yana; Alvina Christy Maretta; Mariani Mariani; Fiola Yonandes; Alfiya Farah Anindhita
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.8152

Abstract

Urinary tract infection (UTI) is a common bacterial infection that requires appropriate antibiotic management to prevent complications and antimicrobial resistance. Ceftriaxone and ciprofloxacin are commonly used antibiotics with different clinical indications in UTI treatment. This literature review aims to compare the role of ceftriaxone and ciprofloxacin in the management of urinary tract infections. A narrative literature review was conducted using articles published within the last ten years from PubMed, ScienceDirect, and Google Scholar databases. The review focuses on clinical effectiveness, resistance patterns, and therapeutic considerations. The findings indicate that ceftriaxone is primarily used in moderate to severe or complicated UTIs, particularly in hospitalized patients, whereas ciprofloxacin is more frequently used in uncomplicated UTIs in outpatient settings. However, increasing bacterial resistance and safety concerns limit the empirical use of ciprofloxacin. These findings emphasize the importance of rational antibiotic selection based on clinical conditions and local resistance patterns.  
Integrasi Presisi Profil Molekuler Radiologis dan Klinis dalam Diagnosis dan Penatalaksanaan Congenital Megacalyces Rian Hendriyana Dwi Imanta; Fairuz Rafi Fadlurrahman; Maya Ganda Ratna; Giska Tri Putri
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.8158

Abstract

Congenital Megacalyces is a rare anomaly of the renal pelvis-calyceal system characterized by non-obstructive calyx dilatation due to renal medulla hypoplasia. This condition is often misinterpreted as hydronephrosis, leading to unnecessary surgical interventions. Advances in genomic technology and precision imaging have opened up opportunities to understand the molecular basis and anatomical structure of this anomaly more deeply. A literature review was conducted through PubMed, ScienceDirect, and Google Scholar, covering publications that discuss the relationship between genomics, imaging, and clinical management of congenital kidney abnormalities. The integration of Next Generation Sequencing (NGS), 3D MRI reconstruction imaging, and AI-based radiomics analysis has proven to enhance diagnostic accuracy, differentiate between obstructive and non-obstructive abnormalities, and assist in determining appropriate conservative therapies. Case studies demonstrate the association between SETBP1 mutations and the development of bilateral megacalyces, as well as the effectiveness of long-term monitoring based on multimodal data. The integration of genetic, imaging, and clinical data is a strategic step toward precision medicine in the management of Congenital Megacalyces. This approach improves diagnostic accuracy, reduces unnecessary invasive interventions, and supports individualized therapy based on genetic and anatomical risk factors.
Co-Authors Ade Yonata Alfiya Farah Anindhita Alvina Christy Maretta Dafa Rafiqi Akbar Fairuz Rafi Fadlurrahman Fiola Yonandes Giska Tri Putri Mariani Mariani Meta Tri Yana Rian Hendriyana Dwi Imanta Sinta Nurmalasari