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All Journal Indonesian Journal of Cardiology Heart Science Journal
Siska Suridanda Danny
Cardiology Consultant, Intensive Care And Cardiovascular Emergency Division / Faculty Of Medicine University Indonesia / National Cardiovascular Center Harapan Kita
Health Professions Immunology & microbiology Medicine & Pharmacology

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Faktor-Faktor yang Mempengaruhi Kejadian Kardiovaskular Mayor pada Wanita Pasca Infark Miokard Akut Siska Suridanda Danny; Poppy S Roebiono; Amiliana M Soesanto; Manoefris Kasim
Jurnal Kardiologi Indonesia Vol. 30, No. 1 Januari - April 2009
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v30i1.171

Abstract

Background.Cardiovascular mortality had decreased significantly in men during the last 20 years but the decrease of mortality in women stayed more subtle. Age-group analysis toward this lack of decline showed that gender difference especially evident in subjects aged less than 55 years. This study aimed to investigate the rate of Major Adverse Cardiovascular Events (MACE) occurred in women after Acute Myocardial Infarction (AMI) and associated predictors, along with the differences in clinical characteristics between age groups which could potentially cause a disparity in outcome.Methods.This was a retrospective cohort study by medical records analysis. We investigated female patients presenting to Emergency Departement National Cardiovascular Center Harapan Kita Jakarta (NCCHK) with AMI during January-December 2007. Investigation toward the occurrence of MACE was undertaken in February-March 2009. Results.Female patients constituted 22.4% of all patients diagnosed as Acute Coronary Syndrome. There were a total of 168 patients with AMI, followed for 14-26 months (mean follow up time of 16.6 months). The incidence of MACE was 51.7%. Intra hospital mortality was 16.7% while overall mortality was 30.9%. Predictors for MACE were Diabetes Mellitus (DM) with HR 2.293 (95% CI: 1.099-4.783 p=0.027), and coronary lesion affecting 3 vessel/Left Main disease with HR 4.217 (95% CI: 1.907-9.280 p<0.001). Age-group analysis showed that in women more than 55 years of age, predictors of MACE included also DM and coronary lesion affecting 3 vessel/Left Main disease, along with history of previous angina. However, in women less than 55 years of age, the incident of MACE can not be predicted by clinical factors investigated by this study.Conclusions.AMI in women poses a high rate of MACE and death in all age groups. AMI occurred in younger women constitutes a high risk group with different disease profile which is difficult to predict by traditional risk factors.
Ablasi Radiofrekuensi pada Kepak Atrium Tipikal Setelah Pemasangan Amplatzer Septal Occluder : Suatu Laporan Kasus Siska Suridanda Danny; Yoga Yuniadi; Amir Aziz Alkatiri; Faris Basalamah; Muhammad Munawar
Jurnal Kardiologi Indonesia Vol. 29, No. 2 Mei - Agustus 2008
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v29i2.192

Abstract

We report a case of a 48-year old female with secundum atrial septal defect (ASD), already undergone device closure with an Amplatzar Septal Occluder (ASO). The patient subsequently underwent radiofrequency catheter ablation for typical atrial flutter, three months after ASD closure with good results. During follow up the patient remained in sinus rhythm and the complaints of dyspnoe and palpitation subsided.
Terapi Resinkronisasi Jantung pada Penanganan Gagal Jantung Hilman Zulkifli Amin; Siska Suridanda Danny
Jurnal Kardiologi Indonesia Vol. 36, No. 4 Oktober - Desember 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i4.506

Abstract

Heart failure (HF) is a worldwide health problem with high prevalence rate. The prevalence is over 23 million worldwide. It is a chronic disease characterized by the inability of the heart to pump an adequate amount of blood to achieve the demand of the different organ systems and/or doing so at increased filling pressures. Despite many recent advances in medication, the rate of people with HF is rising. This health challenges need to be answered properly. One of the new important treatment for HF is cardiac resynchronization therapy (CRT). Many patients with HF also have an abnormality of the heart’s electrical system resulting in asynchronous contraction pattern of heart muscle.The ultimate goal of CRT is to restore synchrony of the heart rhythm in HF patients. CRT implantation in heart failure patients with proper indications like wide QRS complexes, low left ventricular ejection fraction (LVEF), and left bundle branch block (LBBB) has been proved to reduce morbidity, mortality, and also improve symptoms and quality of life (QoL).
PERFORMA SIMPLIFIED ACUTE PHYSIOLOGY SCORE 3 SEBAGAI PREDIKTOR MORTALITAS PADA UNIT RAWAT INTENSIF KARDIOVASKULAR Akhtar Fajar Muzakkir; Dafsah Arifa Juzar; Andi Alfian Zainuddin; Dwi Yuda Herdanto; Bambang Widyantoro; Dian Zamroni; Siska Suridanda Danny; Isman Firdaus; Daniel PL Tobing; Irmalita Irmalita
Jurnal Kardiologi Indonesia Vol 39 No 4 (2018): Indonesian Journal of Cardiology: October-December 2018
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v39i4.702

Abstract

Background: Severity of illness scoring systems has gained increasing popularity in Intensive Care Units (ICUs) since 1980s. Physicians used them for predicting mortality and assessing illness severity in clinical trials. The Simplified Acute Physiology Score 3 (SAPS 3) is the only score that can predict hospital mortality within an hour of admission to ICU. Although this scoring systems has been widely used in ICUs, they have not been commonly applied in Intensive Cardiovascular Care Units (ICVCUs) since the population is quite different especially in disease subset. Therefore, the objective of this study was to evaluate the parameters in the SAPS 3 scoring system performance for predicting mortality in ICVCU population.Methods: This was an observational study with cross-sectional approach using secondary data from RAICOM (Registry of Acute and Intensive Cardiovascular Care on Outcome) taken from September 2013 – September 2014 in the ICVCU National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia. The secondary data were collected, analysed, and matched with SAPS 3 variables. All missing and invalid data were excluded. All data was processed and the SAPS 3 score was calculated in each patient. Multivariate analysis with logistic regression was conducted to evaluate the significance of the parameters in predicting mortality. Discrimination was assessed by area under the receiver operator characteristic curve (AUROC). Calibration was assessed by Hosmer-Lemeshow goodness-of-fit test through calculating the ratio of observed?to?expected numbers of deaths.Results: A total of 233 patients were included in this study and the observed hospital mortality was 16.7% (39/233). The patients enrolled were divided into survivors and nonsurvivors. Bivariate analyses of SAPS 3 variables showed intra-hospital location before ICVCU admission, use of vasoactive agents, reasons for ICVCU admission, infection, Glasgow Coma Score (GCS), creatinine level, and platelet count were significantly different between nonsurvivors than survivors (P<0.05). The SAPS 3 score was significantly higher in nonsurvivors than survivors. The AUC (95% confidence intervals [CIs]) for SAPS 3 score was 0.752 (0.669–0.835). The Hosmer?Lemeshow goodness?of?fit test for SAPS 3 demonstrated a Chi?square test score of 1.729, P = 0.943. Multivariate logistic regression was conducted for all variables that were probably correlated to prognosis. Eventually, intermediate ward as intra-hospital location before ICVCU admission was selected as an independent risk factors for predicting mortality (OR 4.165; 95% CI 1.462-11.864; P=0.008), whereas surprisingly the presence of community-acquired pneumonia (CAP) before ICVCU admission was a protective factor from hospital mortality (OR 0.224; 95% CI 0.068-0.730; P=0.013).Conclusion: Parameters in the SAPS 3 score system exhibited satisfactory performance in discrimination. In predicting hospital mortality, these parameters also showed good calibration for estimating hospital mortality. Intermediate ward as intra-hospital location before ICVCU admission appeared to be independently associated with mortality whereas patients with CAP comorbid as a protective factor against mortality. Despite the good result of this study, there are still plenty room of improvement for developing similar score in the future specifically for ICVCU population.
The Current Concept and Role of Intensive Cardiovascular Care Units Siska Suridanda Danny
Heart Science Journal Vol 4, No 1 (2023): Optimizing Outcome in Acute Cardiac Care
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.01.1

Abstract

Since its first establishment in the early 1960s, intensive care for the critically ill cardiac patients had transformed substantially. From a unit designed only to monitor cardiac rhythm and administer electrical therapy to patients with myocardial infarction (MI), the Intensive Cardiovascular Care Units (ICVCU) now provide care for a wide array of patients with cardiovascular conditions needing close observation and hemodynamic support. This shift in role is accompanied with the development of cardiac critical care as an emerging subspecialty of cardiovascular medicine. Cardiac intensivists should have proper training in general cardiology, combined with additional competency in critical care, including mechanical ventilation, renal replacement therapy, mechanical circulatory support and general preventive measures for infections. A high-intensity medical staffing in a closed care system had shown to improve mortality in critically ill cardiac patients in the contemporary ICVCUs. As interventional cardiology, structural heart disease, electrophysiology, advanced heart failure and transplantation continue to offer new treatment options for complex high-risk patients, cardiac critical care is of utmost importance to provide collaborative care among these disciplines. 
Triglyceride Glucose Index as a Predictor of 30-Day Readmission and 6 Months Mortality After Hospitalization in Acute Decompensated Heart Failure Rezeki, Arindya; Widyantoro, Bambang; Rossimarina, Vienna; Dwiputra, Bambang; Danny, Siska Suridanda; Sukmawan, Renan; Santoso, Anwar
Jurnal Kardiologi Indonesia Vol 44 No 2 (2023): Indonesian Journal of Cardiology: April - June 2023
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1380

Abstract

Background: Acute decompensated heart failure (ADHF) is a cardiovascular disease with high mortality and readmission rates. Currently, insulin resistance has been reported to predict prognosis of ADHF patients. Triglyceride glucose index (TyG) has now been proposed as an independent predictor of cardiovascular risk and a simple marker of insulin resistance. However, the association between TyG and 30-days readmission and 6 months mortality after hospitalization remains unclear. Objective: To investigate TyG as a predictor of 30-day readmission and 6 months mortality after hospitalization in ADHF patients. Methods: The study was conducted in a retrospective cohort. Data were taken from medical records based on the admission of patients who met the inclusion criteria from January 2018 – November 2021. The clinical outcomes were 30-days readmission and 6 months mortality. The data were analyzed by multivariate analysis and the survival rate of the subjects. Results: This study included 467 subjects, with 158 subjects have clinical outcomes. The readmission rate is 29% (135 subjects), and 6 month mortality after hospitalization is 5% (23 subjects). Multivariate analysis showed that the factors associated with 30-days readmission were hypertension (p 0.03, HR 1.547, CI 95% 1.044 – 2.291), systolic blood pressure > 140 mmHg on admission (p< 0.001, HR 0.441, CI 95% 0.296 – 0.658), triglyceride ³ 150 mg/dL (p 0.012, HR 1.812, CI 95% 1.139 – 2.881), and TyG index (p <0.001, OR 4.594, CI 95% 2.717 – 7.767). Independent factors for 6 months mortality were only no diuretic medication (p 0.02, HR 6.015, CI 95% 1.975 – 18.320). Conclusion: Triglyceride glucose index can predict 30-days readmission, but does not associated with 6-months mortality in ADHF patients.This article has a related Erratum.
The IndONEsia ICCU Registry Juzar, Dafsah Arifa; Bagaswoto, Hendry Purnasidha; Muzakkir, Akhtar Fajar; Habib, Faisal; Astiawati, Tri; Prasetya, Indra; Wirawan, Hendy; Ilhami, Yose Ramda; Djafar, Dewi Utari; Sungkar, Safir; Danny, Siska Suridanda
Jurnal Kardiologi Indonesia Vol 44 No 4 (2023): Indonesian Journal of Cardiology: October - December 2023
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1603

Abstract

Introduction: Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions. However, a widely applicable scoring system to predict patient outcomes in the ICCU is lacking. Therefore, developing and validating scores for predicting ICCU patient outcomes are warranted. The aims of the IndONEsia ICCU (One ICCU) registry include developing an epidemiological registry of ICCU patients and establishing a multicentre research network to analyse patient outcomes. Methods and results: This nationwide multicenter cohort protocol will capture data from patients receiving cardiovascular critical care treatment in 10 Indonesian hospitals with ICCU facilities. Recorded data will encompass demographic characteristics, physical examination findings at hospital and ICCU admission, diagnoses at ICCU admission, therapy, intervention, complications on days 3 and 5 of in-ICCU care, in-hospital outcomes, and 30-day outcomes. Conclusion: The One ICCU is a large, prospective registry describing the care process and advancing clinical knowledge in ICCU patients. It will serve as an investigational platform for predicting the mortality of ICCU patients.
Longitudinal Strain Assessment Of Myocardial Dysfunction In Covid-19 Patients: Correlating Clinical Symptoms And Laboratory Results At Admission And Four Months Post-Treatment Liastuti, Lies Dina; Tanto, Ines Vidal; Rachman, Aditya; Robot, Marselly Maria; Dwiputra1, Bambang; Ariani, Rina; Danny, Siska Suridanda; Taofan, Taofan; Sukmawan, Renan
Jurnal Kardiologi Indonesia Vol 45 No 1 (2024): January - March, 2024
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1685

Abstract

Background: Myocardial dysfunction is increasingly recognized as a complication of COVID-19 infection, with implications for patient prognosis and long-term cardiovascular health. Longitudinal strain, measured via echocardiography, is a sensitive marker of myocardial function that may provide valuable insights into cardiac involvement in COVID-19 patients. This study aimed to assess myocardial dysfunction using longitudinal strain analysis in COVID-19 patients, correlating clinical symptoms and laboratory results at admission and four months post-treatment. Methods : This study compared clinical and laboratory parameters in COVID-19 patients post-recovery with and without myocardial dysfunction. Adult COVID-19 survivors were included if they were hospitalized and met certain criteria. Independent variables included clinical factors and laboratory factors at admission, while the dependent variable was myocardial dysfunction assessed through longitudinal strain of the left and right ventricles on speckle tracking echocardiography. The study was conducted at the Harapan Kita Heart and Blood Vessel Center (RSJPDHK - FKUI)/Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Jakarta. Results: This study examined the cardiovascular health of 162 participants three months after getting infected with COVID-19. Those with comorbidities had the lowest LV GLS levels. Admission factors like obesity, SpO2, and PaO2 levels were linked to decreased LV GLS levels. These findings suggest that these admission factors may predict the progression of COVID-19 syndrome and its implications on cardiovascular health. Conclusion: COVID-19 patients with cardiovascular comorbidities have lower LV-GLS values. CAD status during admission affects LV GLS values 3-6 months after COVID-19 infection, indicating myocardial dysfunction. Basal lateral LV-GLS correlates with obesity status, SpO2, and PaO2 during admission. Closely monitor COVID-19 patients with cardiovascular comorbidities and recognize the implications of CAD status on myocardial function post-infection.
Management of Decongestion in Acute Heart Failure: Time for a New Approach? Pramudyo, Miftah; Putra, Iwan Cahyo Santosa; Zulkarnain, Edrian; Danny, Siska Suridanda; Bagaswoto, Hendry Purnasidha; Anjarwani, Setyasih; Mazwar, Irmaliyas; Juzar, Dafsah Arifa; Pratama, Vireza; Habib, Faisal; Ispar, Akhtar Fajar Muzakkir Ali; Widyantoro, Bambang
Jurnal Kardiologi Indonesia Vol 43 No 2 (2022): Indonesian Journal of Cardiology: April - June 2022
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1381

Abstract

As the primary cause of hospitalization in acute heart failure (AHF) patients, congestion was responsible for a higher risk of mortality, rehospitalization, and renal dysfunction in AHF patients. Although loop diuretic was routinely used as the mainstay of AHF therapy, it is still ineffective to obtain the euvolemic state in most hospitalized AHF patients. Therefore, a higher loop diuretic dose was often required to increase the decongestion effect. However, consequently, it can cause several detrimental complications, including renal dysfunction, neurohormonal activation, hyponatremia, hypokalaemia, and reduced blood pressure, which eventually result in poor prognosis. Hence, the new approach may be proposed to optimize decongestion in acute phase, including the use of arginine vasopressin V2 receptor antagonist – Tolvaptan. As an additive therapy to loop diuretic in AHF patients, it can be considered due to its several beneficial effects, including greater decongestion effect, lowered worsening renal function incidence, counteract neurohormonal activation, neutralized hyponatraemic state, no alteration of potassium metabolism, stabilize the blood pressure, and reduced requirement of a higher dose of loop diuretic to achieve an equal or even greater decongestion effect compared to a high dose of loop diuretic alone. Tolvaptan provided favourable outcomes in several specific populations and was considered safe with several mild adverse effects. Several guidelines across countries have approved the use of Tolvaptan in AHF patients with or without hyponatremia. The initial dose of Tolvaptan was 7.5 to 15 mg and can be titrated up to 30 mg. However, further studies were still required to determine the timing dose and optimal dose of Tolvaptan in general and elderly populations with AHF, respectively.This article has a related Erratum.
Management of Decongestion in Acute Heart Failure: Time for a New Approach? Pramudyo, Miftah; Putra, Iwan Cahyo Santosa; Zulkarnain, Edrian; Danny, Siska Suridanda; Danny, Hendry Purnasidha; Anjarwani, Setyasih; Mazwar, Irmaliyas; Juzar, Dafsah Arifa; Pratama, Vireza; Habib, Faisal; Ispar, Akhtar Fajar Muzakkir Ali; Widyantoro, Bambang
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2036

Abstract

In “Management of Decongestion in Acute Heart Failure: Time for a New Approach?” (Indonesian Journal of Cardiology, 43(2), 77-89. https://doi.org/10.30701/ijc.1381), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1381. The error occurs only in the PDF; the DOI listed in the article metadata is already correct. The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1381
Co-Authors Aditya Rachman, Aditya Akhtar Fajar Muzakkir Akhtar Fajar Muzakkir Amiliana M. Soesanto Amir Aziz Alkatiri Andi Alfian Zainuddin Anjarwani, Setyasih Anwar Santoso Anwar Santoso Ariani, Rina Astiawati, Tri Bambang Widyantoro Dafsah Arifa Juzar Daniel PL Tobing Danny, Hendry Purnasidha Dewi Utari Djafar, Dewi Utari Dian Zamroni Dwi Yuda Herdanto Dwiputra, Bambang Dwiputra1, Bambang Erwinanto Erwinanto Faisal Habib Faisal Habib Faris Basalamah Habib, Faisal Hendry Purnasidha Bagaswoto Hendry Purnasidha Bagaswoto Hilman Zulkifli Amin Ilhami, Yose Ramda Indra Prasetya Irmalita Irmalita Isman Firdaus Ispar, Akhtar Fajar Muzakkir Ali Jonathan Edbert Afandy Jonathan Edbert Afandy Liastuti, Lies Dina Manoefris Kasim Mazwar, Irmaliyas Miftah Pramudyo Mikhael Asaf Mikhael Asaf Muhammad Munawar Muzakkir, Akhtar Fajar Poppy S Roebiono Pratama, Vireza Putra, Iwan Cahyo Santosa Renan Sukmawan Rezeki, Arindya Robot, Marselly Maria Rossimarina, Vienna Sunanto Ng Sungkar, Safir Tanto, Ines Vidal Taofan, Taofan Wirawan, Hendy Yoga Yuniadi Zulkarnain, Edrian