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All Journal Jurnal Biodjati Indonesian Journal of Cardiology Poltekita: Jurnal Pengabdian Masyarakat Jurnal Ilmu Kesehatan Indonesia (JIKSI) Poltekita: Jurnal Pengabdian Masyarakat
Ilhami, Yose Ramda
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Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Management of Acute Coronary Syndrome Indonesia : Insight from One ACS Multicenter Registry Juzar, Dafsah Arifa; Muzakkir, Akhtar Fajar; Ilhami, Yose Ramda; Taufiq, Nahar; Astiawati, Tri; R A, I Made Junior; Pramudyo, Miftah; Priyana, Andria; Hakim, Afdhalun; Anjarwani, Setyasih; Endang, Jusup; Widyantoro, Bambang
Jurnal Kardiologi Indonesia Vol 43 No 2 (2022): Indonesian Journal of Cardiology: April - June 2022
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1406

Abstract

Background Acute coronary syndrome (ACS) is a life-threatening disorder which contributes to high morbidity and mortality in the world. Registry of ACS offers a great guidance for improvement and research. We collated a multicentre registry to gain information about demographic, management, and outcomes of ACS in Indonesia. Methods IndONEsia Acute Coronary Syndrome Registry (One ACS Registry) was a prospective nationwide multicenter registry with 14 hospitals participating in submitting data of ACS via standardized electronic case report form (eCRF). Between July 2018 and June 2019, 7634 patients with ACS were registered. This registry recorded baseline characteristics; onset, awareness, and transfer time; physical examination and additional test; diagnosis; in-hospital medications and intervention; complications; and in-hospital outcomes. Results Nearly half of patients (48.8%) were diagnosed with STE-ACS. Most prevalent risk factors were male gender, smoking, hypertension. Patients with NSTE-ACS tended to have more concomitant diseases including diabetes mellitus, dyslipidemia, prior AMI, HF, PCI, and CABG. Majority of ACS patients in our registry (89.4%) were funded by national health coverage. Antiplatelet, anticoagulant, antihypertensive, and statins were prescribed as 24-hours therapy and discharge therapy; however presription of potent P2Y12 inhibitor was low. More STE-ACS patients underwent reperfusion therapy than non-reperfusion (65.2% vs. 34.8%), and primary PCI was the most common method (45.7%). Only 21.8% STE-ACS patients underwent reperfusion strategy within 0-3 hours of onset. Invasive strategy performed in 17.6% of NSTE-ACS patients, and only 6.7% performed early (within <24 hours). Patients underwent early invasive strategy had a shorter median LoS than late invasive strategy (P<0.001). A shorter median LoS also found in intermediate and low risk patients. Mortality rate in our ACS patients was 8.9%; STE-ACS patients showed higher mortality than NSTE-ACS (11.7 vs. 6.2%). Conclusion Our registry showed a comparable proportion between STE- and NSTE-ACS patients, with male gender predominant in middle age. Both STE- and NSTE-ACS sharing the same risk factors. We need an improvement in referral time, especially in patients with STE-ACS. Evidence from our registry showed that there are two issues that need to be addressed in order to improve ACS outcomes: optimal and adequate medical treatment and invasive strategy. This article has a related Erratum.
The IndONEsia ICCU Registry Juzar, Dafsah Arifa; Bagaswoto, Hendry Purnasidha; Muzakkir, Akhtar Fajar; Habib, Faisal; Astiawati, Tri; Prasetya, Indra; Wirawan, Hendy; Ilhami, Yose Ramda; Djafar, Dewi Utari; Sungkar, Safir; Danny, Siska Suridanda
Jurnal Kardiologi Indonesia Vol 44 No 4 (2023): Indonesian Journal of Cardiology: October - December 2023
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1603

Abstract

Introduction: Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions. However, a widely applicable scoring system to predict patient outcomes in the ICCU is lacking. Therefore, developing and validating scores for predicting ICCU patient outcomes are warranted. The aims of the IndONEsia ICCU (One ICCU) registry include developing an epidemiological registry of ICCU patients and establishing a multicentre research network to analyse patient outcomes. Methods and results: This nationwide multicenter cohort protocol will capture data from patients receiving cardiovascular critical care treatment in 10 Indonesian hospitals with ICCU facilities. Recorded data will encompass demographic characteristics, physical examination findings at hospital and ICCU admission, diagnoses at ICCU admission, therapy, intervention, complications on days 3 and 5 of in-ICCU care, in-hospital outcomes, and 30-day outcomes. Conclusion: The One ICCU is a large, prospective registry describing the care process and advancing clinical knowledge in ICCU patients. It will serve as an investigational platform for predicting the mortality of ICCU patients.
Upaya Membangun Kesadaran Tentang Hidrasi Anak Sekolah Full Day di Padang Fasrini, Ulya Uti; Ilhami, Yose Ramda; Lailani, Mutia; Welan, Rahmani; Irramah, Miftah
Poltekita: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2024)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v5i2.3582

Abstract

Adequate fluid intake is associated with students' attention, memory function, and cognitive performance. Sekolah Alam Ar Royyan, one of the schools highlighted in the G20, needs assistance with students' low water drinking behavior. The hydration team's preliminary research found that most students were mild-moderate dehydrated, which was closely related to action. This activity aims to build awareness of the school and its community to build a culture of drinking enough water at school. The method used was action research involving school administrators, students, and teachers. The researcher identifies specific problems, collects relevant data, analyzes the data, and then decides on the needed actions to overcome these problems. After implementing a series of activities, the team conducted the evaluation. The results showed that eight out of ten students were moderately dehydrated, had low water drinking habits at school, and had limited availability of clean drinking water. After conducting activities with a participatory approach, water drinking at school began to increase, although yet to be significant, and the school has provided drinking water in gallons that students can access while at school in each classroom. This activity concludes that there has been an increase in awareness from the entire school academic community about fulfilling the adequacy of students' drinking water at school.
Peningkatan Pelayanan Kesehatan Lansia Melalui Pembinaan Kader Kesehatan Puskesmas Padang Kandis, Kab. 50 Kota Sumatera Barat Irramah, Miftah; Afriwardi, Afriwardi; Amir, Arni; Anggraini, Fika Tri; Irawati, Lili; Ilhami, Yose Ramda; Syawqi, Rahmat; Lailani, Mutia; Sari, Desy Nofita
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.2003

Abstract

As the global population increases, the need for effective elderly care becomes increasingly urgent. Health cadres play a crucial role in improving the health and well-being of communities. One of the strategies to address this need is training health cadres, who can serve as vital links between healthcare providers and the elderly. In this training program, we aimed to enhance the role of health cadres in elderly care to support the physical, mental, and social well-being of the elderly. Through interactive exercises and providing health cadre pocketbooks, participants learned how to assess the individual needs of the elderly and increase their motivation to visit nearby healthcare facilities, thus improving the health status of the elderly in the region of Nagari Padang Kandis, district of 50 Kota. The activity involved 15 elderly health cadres. This training showed a 25% increase in the cadres' knowledge, as improved pre-test and post-test scores indicated. The health cadres now possess the skills and knowledge to effectively support the elderly community in their environment, fostering an independent and active elderly population in their daily activities and reducing dependence on the productive-age population. Furthermore, this community engagement activity, involving collaboration between the academic community of the Faculty of Medicine, Universitas Andalas, and the Padang Kandis health center, will be conducted periodically to enhance the health status of the local individuals in their society life.
Hubungan Diabetes Melitus dengan Kematian dan Rehospitalisasi Pasien STEMI Pasca IKPP Sylvia; Elfi, Eka Fithra; Putri, Biomechy Octomalio; Ilhami, Yose Ramda; Anggraini, Fika Tri
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 4 (2025): Desember 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i4.1467

Abstract

Latar Belakang: ST-Elevation Myocardial Infarction (STEMI) tetap menjadi tantangan kesehatan utama dengan risiko kematian dan rehospitalisasi yang lebih tinggi pada pasien dengan diabetes melitus (DM). Meskipun intervensi koroner perkutan primer (PPCI) efektif menurunkan angka kematian dibandingkan terapi fibrinolitik, pasien DM menghadapi risiko komplikasi lebih besar karena kerusakan vaskular dan hiperglikemia. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan DM dengan kematian dan rehospitalisasi padapasien STEMI pasca IKPP di RSUP. Dr. M. Djamil Padang Metode: Penelitian ini merupakan penelitian analitik obsevasioal dengan desain cross sectional. Penelitian ini menggunakan data sekunder rekam medik pasien dan  menggunakan media telepon. Teknik pegambilan sampel adalah total sampling dengan 104 subjek memenuhi kriteria penelitian. Hasil: Dari 104 sampel yang memenuhi kriteria inklusi, terdapat 89 laki-laki, usia dominan 45–64 tahun (n=62), 69 memiliki IMT ≥23, 39 dengan lokasi infark anterior, 69 perokok, 101 mengalami penurunan kadar HDL, 71 mengalami peningkatan kadar LDL, dan 85 memiliki faktor risiko ganda. Terdapat 9 kasus kematian (8 dengan DM) dan 19 kasus rehospitalisasi (14 dengan DM), dengan korelasi signifikan antara DM dengan kematian (p=0,015) serta rehospitalisasi (p=0,034). Kesimpulan: Kesimpulan penelitian ini menunjukkan pasien STEMI didominasi laki-laki, usia 45-64 tahun, dengan IMT ≥23, penurunan HDL, peningkatan LDL, lokasi infark anterior, faktor risiko ganda, dan merokok. Kejadian kematian dan rehospitalisasi lebih sering pada pasien dengan diabetes melitus, dengan hubungan signifikan terhadap peningkatan risiko keduanya
The Role of Endothelial Microparticle in Coronary Heart Disease as The Complications of Diabetes Mellitus Elfi, Eka Fithra; Ilhami, Yose Ramda; Darwin, Eryati
Jurnal Biodjati Vol 4 No 1 (2019): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v4i1.4164

Abstract

  Coronary heart disease (CHD) is caused by obstruction of coronary blood flow due to endothelial dysfunction triggered by various genetic and non-genetic risk factors such as hyperlipidemia, hypertension, hyperglycemia and obesity. Endothelial cell activation due to hyperglycaemia in diabetes mellitus induces production of pro-inflammatory factors that damage the cell membrane triggering the formation of membrane particles called microparticles. Endothe-lial microparticles contain proteins including endothelial nitric oxide synthase (eNOS) which plays a role in the production of nitric oxide (NO). To determine the role of microparticles in the occurrence of coro-nary heart disease in diabetes mellitus due to endothelial dysfunction, a study was conducted by comparing the levels of eNOS and NO in DM patients who had CHD with DM patients who had no CHD. Blood samples from 20 DM patients who had CHD and 20 DM patients who had no CHD of the outpatients in Cardiology Department and Inter-nal Medicine department of regional public hospital were included in this study. All patients were fulfilled inclusion and exclusion criteria and diagnosed by the appropriate specialist. The eNOS and NO lev-els were measured using the ELISA method. The results of this study show that eNOS levels in the group of DM patients who had CHD (21,292±12,415 ng/ml) were significantly lower (p <0.05) than those in the group of DM patients who had no CHD (29,721±11,952 ng/ml). Nitric oxide levels in DM patients who had CHD (0,053±0,021 nmol/ μl) were not statistically different to the levels in DM patients who had no CHD (0,047±0,032 nmol/μl). From the results of this study we concluded that endothelial microparticle protein eNOS plays a role in the occurrence of CHD due to the complications of diabetes mellitus 
Management of Acute Coronary Syndrome Indonesia: Insight from One ACS Multicenter Registry Juzar, Dafsah Arifa; Muzakkir, Akhtar Fajar; Ilhami, Yose Ramda; Taufiq, Nahar; Astiawati, Tri; R A, I Made Junior; Pramudyo, Miftah; Priyana, Andria; Hakim, Afdhalun; Anjarwani, Setyasih; Endang, Jusup; Widyantoro, Bambang
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2005

Abstract

In “Management of Acute Coronary Syndrome in Indonesia: Insight from One ACS Multicenter Registry” (Indonesian Journal of Cardiology, 43(2), 45-55. https://doi.org/10.30701/ijc.1406), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1406. The error occurs only in the PDF; the DOI listed in the article metadata is already correct. The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1406
Co-Authors Afriwardi Afriwardi Andria Priyana Anjarwani, Setyasih Arni Amir Astiawati, Tri Bambang Widyantoro Dewi Utari Djafar, Dewi Utari Eka Fithra Elfi, Eka Fithra Endang, Jusup Eryati Darwin Fereshti Lailani Fika Tri Anggraini Habib, Faisal Hakim, Afdhalun Hendry Purnasidha Bagaswoto Indra Prasetya Juzar, Dafsah Arifa Lili Irawati Miftah Irramah Muzakkir, Akhtar Fajar Nahar Taufiq, Nahar Pramudyo, Miftah Putri, Biomechy Octomalio R A, I Made Junior Siska Suridanda Danny Sungkar, Safir Syawqi, Rahmat Sylvia Ulya Uti Fasrini Wirawan, Hendy