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All Journal Jurnal Mandala Pharmacon Indonesia INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Moch. Saiful Bachri
Universitas Ahmad Dahlan
Health Professions Medicine & Pharmacology Public Health

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Phytochemical Screening Analysis and Determination of Total Flavonoids and Total Phenolics Content of Ethanol Extract of Sungkai Leaf (Penorema canescens Jack) from Samarinda City Muhammad Ma'ruf; Moch. Saiful Bachri; Laela Hayu Nurani
Jurnal Mandala Pharmacon Indonesia Vol. 9 No. 2 (2023): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v9i2.360

Abstract

Sungkai is a plant that contains compounds such as flavonoids, tannins, phenolics, saponins, steroids, and terpenoids, which have the potential to develop native Indonesian herbal medicines to treat the prevention and treatment of various diseases. This research aimed to analyze phytochemical screening and the total flavonoid and phenolic content in sungkai leaves originating from Samarinda City. This research method was carried out by extracting sungkai leaves with 96% ethanol and evaporating them with a vacuum rotary evaporator. Sungkai leaf extract was analyzed for phytochemical screening using the tube method with color testing from various reagents and total phenolic and flavonoid content testing using the colorimetric method using a UV-Vis spectrophotometer. The results of the phytochemical screening showed that the ethanol extract of sungkai leaves from Samarinda City was positive for containing flavonoids, saponins, alkaloids, phenolics, and steroids. The results of determining the flavonoid and phenolic content of sungkai leaf ethanol extract were 18,210 ± 0.271 mg QE/g sample and 33,666 ± 1.052 mg GAE/g sample.
Formulasi dan Uji Aktivitas Antioksidan Gel Ekstrak Etanol Daun Jeruk Nipis (Citrus aurantifolia) dengan Kombinasi Ekstrak Etanol Daun Kelor (Moringa oleifera Lam) Nur Rohma Inayah Bahun; Annisa Fatmawati; Nurul Jannah; Moch. Saiful Bachri
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 8 No. 2 (2024)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v8i2.5136

Abstract

Penuaan dini adalah proses penuaan kulit yang terjadi lebih cepat dari seharusnya, disebabkan oleh faktor internal dan eksternal, terutama radikal bebas. Daun jeruk nipis (Citrus aurantifolia) dan daun kelor (Moringa oleifera Lam) mengandung flavonoid seperti kuersetin, apigenin, rutin, kaempferol, hesperidin, dan nobiletin yang berfungsi sebagai antioksidan untuk menangkal radikal bebas. Penelitian ini bertujuan menguji aktivitas antioksidan formulasi gel kombinasi ekstrak daun jeruk nipis dan daun kelor dengan perbandingan 1:1, 1:2, dan 2:1. Ekstraksi dilakukan melalui maserasi menggunakan etanol 70%, kemudian diformulasi menjadi sediaan gel. Penelitian ini bersifat eksperimental laboratorium dengan evaluasi sifat fisik dan aktivitas antioksidan menggunakan metode DPPH. Hasil evaluasi menunjukkan semua formula memenuhi persyaratan sifat fisik gel, meliputi uji organoleptik, homogenitas, pH, daya lekat, dan daya sebar. Aktivitas antioksidan formula I (1:1) adalah 80,04 ppm, formula II (1:2) 143,67 ppm, formula III (2:1) 94,21 ppm, dan basis gel 328,26 ppm. Formula I dan III tergolong sebagai antioksidan kuat, sedangkan formula II tergolong antioksidan sedang. Kesimpulannya, kombinasi ekstrak daun jeruk nipis dan daun kelor dalam sediaan gel memiliki potensi sebagai antioksidan, terutama formula I dan III
PEMANFAATAN ULANG PELEPAH KELAPA SAWIT (Elaeis guineensis) UNTUK APLIKASI BIOMEDIS MELALUI UJI IN VITRO ANTIBAKTERI, ANTIBIOFILM, DAN ANTIOKSIDAN Deni Setiawan; Samsul Hadi; Nurul Mardiati; Nashrul Wathan; Hilma Aulia; Siti Najwa; Muhammad Rasyid Ridha; Moch. Saiful Bachri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.2869

Abstract

Elaeis guineensis fronds possess significant pharmacological potential, especially as antibiofilm and antioxidant. Previous studies have shown that E. guineensis contains flavonoids, alkaloids, tannins, and steroids that function as antioxidants. This study aims to examine the pharmacological activity of E. guineensis fronds and their antibiofilm potential. Palm fronds were macerated with aceton for 5 days. Antibacterial evaluation was conducted on four types of bacteria, and antibiofilm assessment was performed on S. aureus and E. coli. Evaluation of E. guineensis extract antioxidant activity was carried out using antioxidant tests (DPPH, FRAP, ABTS). The results of the antibacterial test showed good activity against P. acnes bacteria. The results of the antibiofilm evaluation showed significant and concentration-dependent inhibitory activity at a concentration of 1%, especially in the mid-phase for S. aureus and the maturation phase for E. coli. However, effectiveness decreased in the eradication phase. The antioxidant test showed a value of 63.93 ppm in the ABTS test. E. guineensis extract has shown strong potential as an antibacterial against P. acnes and has potential as an antibiofilm and antioxidant.
Co-Authors Deni Setiawan Fatmawati, Annisa Hilma Aulia Laela Hayu Nurani Muhammad Ma'ruf Muhammad Rasyid Ridha Nashrul Wathan Nur Rohma Inayah Bahun Nurul Jannah Nurul Mardiati Samsul Hadi Siti Najwa