Radityo Prakoso
Departemen Kardiologi Dan Kedokteran Vaskular, Fakultas Kedokteran Universitas Indonesia Pusat Jantung Nasional Harapan Kita, Jakarta

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Teknologi Terkini dalam Tatalaksana Intervensi Non Bedah Penyakit Jantung Bawaan Radityo Prakoso; Dewi Hapsari Suprobo
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.67

Abstract

Dalam dua hingga tiga dekade terakhir bidang intervensi kardiak telah mengalami kemajuan yang pesat baik dalam hal jumlah tindakan dan jenis tindakan. Inovasi teknologi telah menopang kemajuan terapi intervensi non bedah penyakit kardiovaskular pada anak-anak dan usia dewasa. Terapi intervensi telah menjadi terapi alternatif yang cukup diterima pada kasus penyakit jantung bawaan, meliputi penutupan defek atrial (ASD), defek septum ventrikel tipe muskular (VSD muskular), duktus arteriosus paten (PDA), memperlebar stenosis aorta dan pulmonal seperti yang akan dibahas di bawah ini, sehingga pasien tidak selalu harus menjalani pembedahan. Adanya terapi intervensi non bedah ini juga sangat membantu mengurangi prosedur pembedahan yang diperlukan. Sedangkan pada beberapa kasus yang kompleks, apabila pendekatan secara per kutan sulit untuk dilakukan atau pasien juga membutuhkan perbaikan pada kelainan kardiak lain, pendekatan secara hibrid yaitu terapi intervensi bedah dikombinasi dengan intervensi perkutan dapat dilakukan pada penderita penyakit jantung bawaan.
Hipertrofi Ventrikel Kiri Disertai Dengan Pembesaran Diameter Osteum Vena Pulmonal Radityo Prakoso; Erika Maharani; Mohammad Syaifur Rohman; Budiyanto Nagawidjaja; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 28, No. 6 November 2007
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v28i6.206

Abstract

Background:Hypertensive heart disease, characterized with left ventricular hypertrophy (LVH), which is usually accompanied with left ventricular dysfunction, is prevalent in the community and associated with increased of ostial pulmonary vein diameter. We investigate pulmonary vein diameter in its relationship to left ventricular hypertrophy.Methods and Results: Ostial pulmonary veins divided into four parts, left superior (LS), right superior (RS), left inferior (LI), and right inferior (RI), were assessed by spiral multisliced computed tomography (MSCT) in 46 sinus rhythm subjects. LVH was analyzed by measuring the thickness of interventricular septum by MSCT. There were 23 patients with LVH, and the rest were normal. According to Pearson correlation analysis, we found a significant positive correlation between the degree of LVH and ostial diameter of RS, RI, and LS (p<0.05).Conclusion:Left ventricular hypertrophy is associated with right superior, right inferior and left superior pulmonary veins dilatation.
Stratifikasi Risiko Kematian Jantung Mendadak pada Sindrom Koroner Akut Jusup Endang; Dewi H Suprobo; Radityo Prakoso; Yoga Yuniadi; Bambang B Siswanto; Nani Hersunarti
Jurnal Kardiologi Indonesia Vol. 34, No. 2 April - Juni 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i2.327

Abstract

Sudden cardiac death is the leading cause of cardiovascular mortality in acute coronary syndrome. Risk stratification scoring tools are available to better identify patients at risk after acute myocardial infarction. In addition plenty of factors and treatment modalities modulate the risk of sudden cardiac death.A case of in-hospital SCD in a young woman with acute anterior STEMI is presented as a trigger to the importance of risk stratification and treatment according to guidelines in preventing SCD.
Giant Coronary Artery Aneurysms in Kawasaki Disease Detected by Multi Detector Computed Tomographic Oktavia Lilyasari; Poppy S Roebiono; Radityo Prakoso; Anna Ulfah Rahajoe; Indriwanto Sakidjan; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 34, No. 2 April - Juni 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i2.331

Abstract

Kawasaki disease is an acute, self -limited vasculitis of unknown etiology that occurs predominantly in infants and young children. The major sequele of Kawasaki disease are related to the coronary arterial system. Cardiac imaging is a critical part in evaluation of all patients with suspected Kawasaki disease. Multi Detector CT (MDCT) provides a safe non-invasive approach to accurately delineate coronary artery anatomic structure. We report a case of a 6 years old boy with history of Kawasaki disease. Multi detector CT scan showed giant aneurysm at proximal LAD, proximal RCA and medium aneurysm at proximal LCX. Patient then treated with the anticoagulant therapy.
Diagnostik Angiografi dan Intervensi Non-Invasif pada Tetralogy of Fallot (Tof) Radityo Prakoso; Danayu Sanni Prahasti
Jurnal Kardiologi Indonesia Vol. 34, No. 4 Oktober - Desember 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i4.378

Abstract

La Maladie Bleue yang dideskripsikan olehLouis Arthur Etienne Fallot pada tahun 1888,merupakan gambaran klinis dari fisiologiyang disebabkan malformasi anatomisPenyakit Jantung Bawaan (PJB) yang saat ini disebutdengan Tetralogy of Fallot (TOF).1 Gambaran utamakelainan ini terdiri dari hubungan interventrikularatau ventricular septal defect, hubungan biventrikulardari cabang aorta yang menaiki otot septum ventrikel,obstruksi aliran ventrikel kanan, dan hipertrofiventrikel kanan. Tiap komponen mempunyai derajatkeparahan yang bervariasi, dan mempengaruhimanifestasi klinis dan tatalaksana penyakit tersebut.1,2Perkembangan tatalaksana TOF dari paliatif menjadibedah korektif pada balita dan anak-anak diikuti denganberkembangnya peran intervensi transkateter.
Pulmonary Doppler Notch Pattern in Relation with Pulmonary Vascular Resistance Index in Patients with Atrial Septal Defect Nurnajmia Curie Proklamartina; Radityo Prakoso; Oktavia Lilyasari; Rina Ariani; Sisca Natalia Siagian; Amiliana Mardiani Soesanto
Jurnal Kardiologi Indonesia Vol 41 No 3 (2020): Indonesian Journal of Cardiology: July - September 2020
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1053

Abstract

Background: Atrial septal defect (ASD) potentially causes pulmonary hypertension (PH) and increased pulmonary vascular resistance (PVR). In previous studies, pulmonary Doppler notch was evident in patients with high PVR. There was a distinct notch pattern in different types of PH. This study aims to examine whether echocardiographic notch pattern could estimate PVR in secundum ASD patients. Methods: Cross sectional study was conducted in secundum ASD patients ≥18 years old who underwent clinically indicated right heart catheterization. Association of notch presence and PVR index (PVRi) and correlation of notch ratio (NR), a parameter of notch location, and PVRi were analyzed. The best cut off of NR value was obtained using the receiver operating characteristics curve. Results: Among 60 patients, the notch was present in 50 patients (83%) and significantly associated with PVRi ≥6 WU.m2 (p<0.0001). Notch ratio and PVRi had a moderate negative correlation (r=-0.410, p=0.003). Receiver operating characteristics curve with area under curve 0.709 showed that cutoff NR value of 1.635 was a good discriminator for PVRi ≥6 WU.m2, with 70% sensitivity, 70% specificity, 56.8% positive predictive value, and 14.9% negative predictive value. Patients were then classified into three groups of notch pattern based on its presence and location, which was significantly associated with PVRi (p<0.0001). Conclusions: Pulmonary Doppler notch pattern is associated with PVRi in secundum ASD patients. This may be used clinically to estimate PVR to aid patient selection for further invasive investigation. Keywords: atrial septal defect, Doppler echocardiography, notch, notch ratio, pulmonary vascular resistance
Pentingnya Mendeteksi Penyakit Jantung Bawaan Lebih Dini: Skrining Fase Prenatal dan Postnatal Bayushi Eka Putra; Radityo Prakoso
Majalah Kedokteran Indonesia Vol 72 No 2 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.2-2022-822

Abstract

Congenital heart disease (CHD) may affect 1% of all pregnancies per year. This means, out of 100 babies there will be 1 baby who will experience CHD.1 Moreover, the latest data from the Global Burden of Disease Study 2017 shows the prevalence reaches 1.6%-1.7% for the Southeast Asia region, including Indonesia.2 On the other hand, Indonesia has a growth rate The population is 1.39% with 4.2-4.8 million babies born per year. 3 Thus, it can be estimated that the number of patients with CHD born in Indonesia is 71,400 to 81,600 babies per year.
The Current Strategy in Managing Congenital and Structural Heart Disease: Find and Treat Them Appropriately Prakoso, Radityo
Heart Science Journal Vol. 5 No. 2 (2024): Challenges in the Management of Congenital Heart and Structural Heart Diseases
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.02.2

Abstract

Significant progress has been made in diagnosing and treating congenital heart defects (CHDs) over the past five decades. Notable advancements include pulse oximetry screening for critical CHDs in newborns and percutaneous, catheter-based procedures, improving outcomes even in developing nations. Recent studies demonstrate favorable outcomes with device closure of acyanotic CHDs, with non-fluoroscopy techniques adopted to minimize radiation risks. Positive results are observed with right ventricular outflow tract (RVOT) stent palliation for late-presenting cyanotic congenital heart diseases such as tetralogy of Fallot (TOF). Novel interventions like reverse Potts shunt anastomosis show promise in managing pediatric pulmonary arterial hypertension (PAH), while prophylactic treatments effectively reduce postoperative arrhythmias. Fontan procedure significantly enhances survival rates for individuals with single functional ventricles, although challenges arise with aging populations. In developed countries, fetal cardiac interventions utilizing advanced imaging techniques allow for early detection and preventive interventions, reducing secondary complications.
Successful High-Risk Pulseless-Balloon Aortic Valvuloplasty Procedure in Uncorrected Pulmonary Atresia with Severe Congenital Aortic Stenosis and Low Left Ventricular Function Sofia, Sefri Noventi; Bahrudin, Bahrudin; Riwanto, Ignatius; Susanto, Hardhono; Soetadji, Anindita; Baskoro, Adhi Gunawan; Prawara, Ananta Sidhi; Satyagraha, Muhammad Thifan; Kurniawati, Yovie; Prakoso, Radityo
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 3 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.72347

Abstract

Background: Pulmonary atresia with ventricular septal defect (PA-VSD) and severe bicuspid aortic stenosis is an uncommon condition that presents significant surgical challenges. The dual obstruction leads to chronic pressure overload, resulting in ventricular hypertrophy and decreased systolic function. A low left ventricular ejection fraction (LVEF) increases the risk of mortality during surgical interventions. Percutaneous balloon aortic valvuloplasty (PBAV) poses additional risks due to the intentional induction of pulselessness during balloon inflation. This case report aims to detail the perioperative management strategies employed during PBAV in a patient with PA-VSD, severe aortic stenosis, and low LVEF.Case: We present a 19-year-old female patient weighing 45 kg with shortness of breath and fatigue. Her oxygen saturation was measured at 90% across all extremities. Electrocardiogram (ECG) findings indicated sinus rhythm with biventricular hypertrophy and incomplete left bundle branch block (LBBB). Chest X-ray revealed cardiomegaly and pulmonary artery dilation, while echocardiography confirmed PA-VSD, severe aortic stenosis with a mean pressure gradient (mPG) of 55 mmHg, and an LVEF of 41.3%. A percutaneous pulseless-BAV was performed using a Tyshak balloon via an antegrade transvenous femoral approach under fluoroscopy and transesophageal echocardiography guidance.Discussion: Anesthesia management focused on gradual medication titration, minimizing patient movement during the procedure, and ensuring comfort due to transesophageal echocardiogram (TEE) probe insertion. A temporary pacemaker was placed in the right ventricular apex for pacing at 220 beats per minute until cardiac arrest occurred post-balloon inflation, and defibrillation successfully restored spontaneous circulation.Conclusion: This case illustrates that PBAV in uncorrected PA-VSD with severe aortic stenosis and low LVEF is feasible despite its inherent risks when conducted by a skilled team utilizing careful judgment throughout the procedure.
Comparison of immediate outcomes between patent ductus arteriosus stenting and modified Blalock-Taussig Thomas shunt in children: a single-center cohort study in Indonesia Novik Budiwardhana; Indah Kartika Murni; Radityo Prakoso; Pribadi Wiranda Busro; Fildza Intan Rizkia; Muhamad Faza Soelaeman; Yunita Widyastuti
Paediatrica Indonesiana Vol. 66 No. 1 (2026): January 2026
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Patients with congenital heart diseases (CHD) involving duct-dependence or inadequate pulmonary blood flow often require early palliative interventions to establish a reliable source of pulmonary circulation. Two common palliative procedures in congenital heart surgery are the modified Blalock-Taussig Thomas (mBTT) shunt and patent ductus arteriosus (PDA) stenting. In developing countries like Indonesia, reducing early mortality and morbidity associated with these procedures remains a significant challenge. A better understanding of which procedure is more suitable under specific clinical circumstances is required to improve outcomes. Objective To compare the immediate outcomes between PDA stenting vs. mBTT shunt in pediatric patients with congenital heart disease as duct-dependence or inadequate pulmonary blood flow requiring aortopulmonary connection. Methods This retrospective cohort study was conducted using hospital data collected between January 2020 and December 2023. During the study period, 228 patients underwent mBTT shunt and 94 underwent PDA stenting. After restricting the cohort to infants ≤12 months and excluding cases with incomplete data, 169 patients were eligible for analysis: 86 in the mBTT shunt group and 83 in the PDA stent group. Results The PDA stent group was significantly younger and had lower body weight than the mBTT shunt group (P<0.001). The mBTT shunt group had longer hospital stays (P=0.014) and higher rates of complications, including shunt obstruction (P=0.042), over-shunting (P=0.007), and arrhythmias (P=0.038). Mortality was higher in the PDA stent group (22.9% vs. 15.1%, respectively), but this difference was not statistically significant (P=0.274). Conclusion PDA stenting was associated with better immediate clinical outcomes compared to mBTT shunt, including shorter PICU and hospital stays, lower vasoactive inotropic score (VIS), reduced over-shunting, and fewer complications. Although mortality was higher in the PDA stent group, the difference was not statistically significant.