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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sain Peternakan Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics & Gynecology Science Global Health Management Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Berita Kedokteran Masyarakat Jurnal Info Kesehatan
Noor Pramono
Departement of Obsterics and Gynecology
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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COMBINATION OF POLYTHYLENE TEREFTALAT NESTING AND PRONE POSITION AT THE STANDARD BOX CARE TO THE VITAL SIGNS AND LENGTH OF STAY ON THE LOW BIRTH WEIGHT BABIES Deviana, Meli; Pramono, Noor; Suwondo, Ari
GHMJ (Global Health Management Journal) Vol 4, No 1 (2020): Online First
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-41269

Abstract

Background: The use of nesting and position prone facilitates Low Birth Weight Babies by conditioning it as in the mother's womb which aims to facilitate Low Birth Weight Babies in the development of physiological functions and achieve physiological function stability.Aims: This study aims to explain the effectiveness of design nesting with material polyethylene terephthalate and the position of prone with standard care using a box of baby warmers for the length of stay which is observed from the achievement of the stability of vital signs on LBW.Methods: This is a Quasi-Experimental Design study with non-equivalent control group design. The study population was all LBW treated in the Perinatal room with a sample of 36 LBW and consecutive sampling. This research was conducted in the Perinatal Room at RSUD RAA Soewondo Pati and RSUD Dr. R. Soetrasno Rembang. Statistical test for paired groups using Wilcoxon and for unpaired groups using Kruskall Wallis.Results: The combination of nesting polyethylene group with position prone achieved faster vital signs stability and shorter duration of treatment compared to the control group with p = 0.001 for temperature, respiration and oxygen saturation.Conclusions: The combination of polyethylene terftalat nesting and prone position is effective to reduce the duration of treatment duration, and may achieve the stability of vital signs of low birth weight infants. This intervention can be used as LBW care during hospital and home care. Keywords: Nesting, Position Prone, Polyethylene Tread, Length of Stay, Baby Vital Signs.
Polycystic Ovary Syndrome Markers and Mechanism Kurniawati, Erna Yovi; Pramono, Noor; Hidayat, Syarief Thaufik; Mahati, Endang
Syifa'Medika Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i1.7829

Abstract

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hormonal imbalances, metabolic dysregulation, and reproductive abnormalities. This study aims to elucidate the significance of PCOS markers and their mechanisms while outlining the methodology employed. A comprehensive literature review was conducted from 2020 to 2023 using databases like PubMed, ScienceDirect, EMBASE, and Google Scholar. Key search terms included "pathophysiology," "pathogenesis," "PCOS," "marker," and "biomarker," aligned with the PICOT criteria. After removing duplicates, articles underwent a two-phase screening process based on predefined inclusion criteria. Additionally, a marker mechanism flowchart was created using the Biorender application. Results highlighted the pivotal role of various markers in understanding PCOS pathophysiology and guiding clinical management. Anthropometric, visual, metabolic, inflammatory, endocrine, and oxidative stress markers were analyzed for their diagnostic, prognostic, and therapeutic implications in PCOS. The study underscores the importance of marker interactions in personalized PCOS management. Limitations in marker interpretation warrant further research to refine diagnostic accuracy and optimize therapeutic interventions. Integrating marker mechanisms enhances understanding of PCOS heterogeneity and informs targeted treatment approaches tailored to individual phenotypic variations.
Perceptions of primigravida and their husbands regarding the need for maternal-fetal attachment stimulation Purwati, Yuni; Pramono, Noor; Hakimi, Mohammad; Sudarmiati, Sari; Anggorowati, Anggorowati
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23913

Abstract

Prenatal class programs for primigravidas are important to improve fetal care behavior and reduce infant mortality. In prenatal classes, there is no maternal-fetal attachment stimulation education program which is important for improving maternal-fetal attachment and fetal well-being. The perceptions of pregnant women and their husbands regarding knowledge and experience of pregnancy as well as maternal-fetal attachment (MFA) stimulation are important for assessing the need for MFA educational materials. The research aimed to examine the perceptions of primigravidas and their husbands regarding pregnancy and MFA stimulation. Exploratory descriptive qualitative study method. Data were collected using in-depth interviews with 10 primigravidas and their husbands at the Community Health Center in Bantul, Yogyakarta, Indonesia, using an interview guide. Data analysis by condensing data, presenting data, and drawing conclusions, verbatim results of interviews are presented in coding, found categories, and themes. Four themes were produced: knowledge of pregnancy and fetal growth and development; concept of maternal-fetal attachment skills; management of pregnancy emotional management; and husband's support. The conclusion of this theme's findings underlies the development of maternal-fetal attachment educational materials in prenatal classes to prepare mothers for their role, and improve MFA and maternal-fetal health.
Factors associated with pregnancy-related anxiety: a health facility-based study Wahyuni, Sri; Pramono, Noor; Hadisaputro, Suharyo; Ediati, Annastasia
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.24327

Abstract

Pregnancy is a critical phase for human beings, which can lead to various mental health issues, including anxiety. It is important to recognize that pregnancy-related anxiety can increase over time and should be addressed. This study aimed to explore the multifactor of pregnancy-related anxiety during the first trimester. A cross-sectional health facility-based study was conducted in four Semarang, Central Java, Indonesia public health centers. A total of 129 pregnant women were involved and identified some exposures, such as socio-demographics, nausea and vomiting during pregnancy (NVP), emotion regulation, social support, and anxiety levels. The average age of participants was 27.3 years. Their anxiety level was moderate to severe (37.2%), and 62.8% were identified as having mild anxiety. This study suggests that pregnant women who lack social support (AOR=4.105; 1.824-9.237) and emotion dysregulation (AOR=2.749; 1.244-6.075) were identified as the risk factors of maternal anxiety during the first trimester. Being employed (AOR=0.410; 0.182-0.922) protects the high anxiety during pregnancy. This study suggests that the lack of social support, including social interaction most influences pregnant women’s mental well-being. Therefore, it may be helpful to establish an intervention plan that strengthens social support to improve maternal mental well-being.
Assasement and Experimental Procedure Polycystic Ovary Syndrome Rat Model: Review Kurniawati, Erna Yovi; Pramono, Noor; Hidayat, Syarief Thaufik; Mahati, Endang
Jurnal Sain Peternakan Indonesia Vol 18 No 4 (2023)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/jspi.id.18.4.242-256

Abstract

A complicated endocrine condition that affects many women worldwide is called polycystic ovarian syndrome, or PCOS. The use of rat models has greatly aided research on many facets of PCOS. In addition to discussing the parameters, evaluation techniques, and indicators pertinent to PCOS research, this study evaluates the standard circumstances of PCOS rat models. Our knowledge of PCOS has improved due to investigating endocrine, hormonal, inflammatory, oxidative stress, metabolic, genetic, and microbiota-related factors in these models. The results highlight how important it is to use PCOS rat models to understand the complexities of this illness and offer possible treatment avenues.
Tikus Wistar yang Diinjeksi Testosterone Propionate Sebagai Hewan Coba Penelitian Mikrobiota Usus pada Sindrom Ovarium Polikistik Dewi Puspitasari, Vannya; Lestari, Endang Sri; Pramono, Noor
Majalah Kedokteran Indonesia Vol 74 No 3 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.3-2024-1461

Abstract

Introduction: Gut microbiota modification based on dysbiosis of gut microbiota dysbiosis (DOGMA) theory may provide a new therapy approach in polycystic ovarian syndrome (PCOS). Research of this new therapy needs a suitable animal model thus this study was aimed to investigate whether Wistar rats that were injected by testosterone propionate (TP) could induce both PCOS and gut microbiota dysbiosis condition.Methods: Design of this study was post-test only control group design randomized control trial. Wistar rats were divided into two groups: control and TP. Blood, faecal and ovarian tissue sampling also vaginal smear were obtained after 28 days of TP injection.Results: TP group had testosterone concentration, preantral follicle and fasting blood glucose concentration higher than control group (p=0.047, p=0.018, p=0.032). Fasting insulin, HOMA-IR value, serum zonulin level, TNF-α concentration and gut microbiota diversity were not significantly different.Conclusion: TP injection intramuscularly (10 mg/kgBW) for 28 days succeeded to induce PCOS and hyperglycaemia in Wistar rat but was failed to induce insulin resistance, low grade inflammation, impaired gut permeability, and gut microbiota dysbiosis thus it’s not suitable as animal model for gut microbiota dysbiosis research in PCOS.
Mean the levels of 25(OH) D in the II trimester of pregnant women at Sleman, Indonesia Susilani, Amalina Tri; Subagio, Hertanto Wahyu; Pramono, Noor; Kartasurya, Martha Irene
BKM Public Health and Community Medicine PHS7 Accepted Abstracts
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: Pregnant women possess a high risk of suffering from a deficiency of vitamin D3. A deficiency of Vitamin D3 is associated with pregnancy-related complications, such as preterm birth, preeclampsia, gestational diabetes, and babies born small for gestational age. Furthermore, it creates a risk of infection and breathing problems when the baby is born, and affects the life of the child. Methods: A descriptive study was done and consisted of participants who met the following criteria: 20 - 35 years of age, BMI between 18.5-24.9, had a record of their last day of menstruation (HPHT). Informed consent was also obtained and signed by all the participants. Women who had histories of preeclampsia and eclampsia, bleeding, premature rupture of membranes, gemelli pregnancy, abortion, and immature births, and mothers with comorbidities such as heart, lung, liver, intestinal, bone, kidney, thyroid, and immunology diseases were excluded from the study. Examination of 25 (OH) D was done using Enzyme-Linked Immuno Sorbant Assay (ELISA) method with 1.5 ml of the sample which had been centrifuged and had its serum extracted. Results: The study began in July 2020 with a total of 80 pregnant women in their second trimester (TM II). The participants had an average height of 154.5 cm and body weight before pregnancy of 51.8 kg. The results obtained showed insufficient levels of 25 (OH) D levels in 72 (90%) participants and sufficient/normal levels in 8 (10%) participants. Conclusion: Most pregnant women at Sleman Indonesia had insufficient levels of 25 (OH) D.
Nausea and Vomiting of Pregnancy: Multiple Contributing Factors Wahyuni, Sri; Pramono, Noor; Hadisaputro, Suharyo; Ediati, Annastasia
JURNAL INFO KESEHATAN Vol 21 No 4 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss4.1388

Abstract

Nausea and vomiting are common conditions in earlier pregnancy. Some studies have suggested that nausea and vomiting during pregnancy (NVP) is caused by multiple factors, however, few studies assessed family support and psychological factors. The present study aimed to assess the prevalence of NVP and its contributing factors. A cross-sectional study was conducted in five Primary Health Centers in Semarang during August 2023. A total of 99 eligible pregnant women were included. A logistic regression was used to determine the significant contributing factors of NVP. The prevalence of moderate to severe and mild NVP was 71.7% and 28.3% respectively. Bivariate analysis indicated that gestational age and anxiety level significantly influence NVP (p-value <0.05). Women with greater gestational age (OR= 2.462; 0.954-6.356) and mild anxiety (OR=3.337; 1.240-8.982) were more likely to experience NVP during their pregnancy. Gestational of 12 weeks and mild anxiety are strongly associated with NVP. These findings highlight the crucial of psychological factors despite other health-related conditions.
Analysis of Consistency The REEDA Scale in Healing Second-Degree Perineal Lacerations Yuniarti, Yuniarti; Pramono, Noor; Cahyono, Bambang; Sera, Agnescia Clarissa
JURNAL INFO KESEHATAN Vol 23 No 1 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss1.1645

Abstract

Many studies of perineal wounds use the redness, edema, ecchymosis, discharge, and approximation (REEDA) scale as a healing assessment tool. Still, this tool has not become part of the standard of care in postpartum women with perineal lacerations due to the lack of evidence of its validity. This study aimed to analyze the consistency of the REEDA scale in healing perineal wounds of postpartum women. The method uses an observational study using the interrater reliability test for the REEDA tool on perineal wound healing in postpartum women with second-degree perineal lacerations, 11 women were recruited using consecutive sampling. Lacerations were observed by researchers, and midwives were trained on days 1, 3, and 7 postpartum. Cohen's kappa coefficient test was used to test the consistency of the REEDA scale. The results shows that the fair and excellent agreement on the redness item with kappa (0.57-1.00), agreement on the edema item showed good and excellent results (0.61-0.84), fair and good agreement on the ecchymosis item (0.51- 0.73), good and excellent agreement on discharge items (0.79 -1.00). On the approximation item (0.62–1.00), agreement improved to excellent at the final assessment. In the third evaluation, the scoring of all items showed good or excellent agreement between the raters.  The conclusion is  the overall assessment shows that the application of the REEDA scale is reliable because it shows consistency; namely, there are no more values with low agreement on the seventh day of the postpartum period.
A Comparative Analysis of Internal Radiation vs Box System in Treatment Efficacy and Patient Survival of Advanced Stage Cervical Cancer Marpaung, Mona Galatia; Iskandar, Teuku Mirza; Pramono, Noor; Suhartono, Suhartono
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 3 November 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i3.942

Abstract

Objectives: To evaluate the comparative effectiveness of brachytherapy and the box system in therapeutic success and patient survival in cervical cancer, along with associated prognostic factors.Methods: This retrospective analytical study used medical records from the Obstetrics & Gynecology Oncology Clinic and Radiotherapy Unit at Dr. Kariadi General Hospital in Semarang. The study included cervical cancer patients with stage IIB-IIIB disease who were treated between January 2017 and December 2022. Data analysis involved both statistical methods and survival analysis using the Kaplan-Meier approach.Results: During the 2017-2022 study period, a total of 939 patients with stage IIB-IIIB cervical cancer who completed full radiation therapy were evaluated for their 2-year survival rate. The cohort included 89 patients in the box system group and 850 in the brachytherapy/internal radiation group. Complete response was achieved in 46.1% of box system patients compared to 75.5% in the brachytherapy group (p<0.0001); partial response rates were 53.9% and 24.5%, respectively. Kaplan-Meier analysis showed a 2-year survival rate (2 YSR) of 41.6% for the box system and 64.0% for brachytherapy. The mean survival time was 15.37 months for the box system and 19.09 months for brachytherapy.Conclusion: Internal radiation therapy (brachytherapy) showed significantly better clinical outcomes compared to the box system approach. It resulted in a longer mean survival time (19.09 vs 15.37 months; p<0.001) and higher 2-year survival rates (64.0% vs 41.6%; log-rank p<0.001).Keywords: Cervical cancer, box system, brachytherapy, therapy response, survivalPerbandingan antara Radiasi Interna vs Box System dalam KeberhasilanTerapi dan Kelangsungan Hidup Pasien Kanker Servik Stadium LanjutAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui perbandingan radiasi interna dan box system dalam keberhasilan terapi dan kelangsungan hidup pasien kanker serviks serta faktor-faktor yang memengaruhi.Metode: Penelitian ini menggunakan metode analitik retrospektif dengan menggunakan rekam medis Poli Kandungan dan Onkologi dan Instalasi Radioterapi RSUP Dr. Kariadi Semarang. Subyek penelitian adalah pasien kanker servik stadium IIB-IIIB mulai periode januari 2017-Desember 2022. Analisis statistika menggunakan analisis analitik dan analisis survival menggunakan metode Kaplan Meier.Hasil: Hasil penelitian menunjukkan bahwa selama tahun 2017– 2022 didapatkan total 939 pasien dengan diagnosis kanker servik stadium IIB-IIIB yang menjalankan terapi radiasi lengkap dan dapat dilakukan evaluasi survival rate 2 tahun. Total subjek pada kelompok box system sebanyak 89, sedangkan kelompok brakiterapi/radiasi interna sebanyak 850 subjek. Respon terapi komplet sebesar 46,1% pada kelompok box system, dan 75,5% pada kelompok radiasi interna, respon terapi parsial 53,9% pada kelompok box system dan 24,5% pada kelompok radiasi interna, dengan nilai p <0.0001. Analisis survival dengan metode Kaplan -Meier didapatkan 2-YSR 41,6% pada kelompok Box system, sedangkan 64% pada kelompok radiasi interna sedangkan mean survival time pada kelompok box system 15,37 bulan dan kelompok radiasi interna 19,09 bulan dengan nilai p <0.001Kesimpulan: Pemberian radiasi interna memberikan keberhasilan terapi klinis yang lebih tinggi dengan nilai mean survival time lebih tinggi. Pemberian radiasi interna memberikan kelangsungan hidup 2 tahun sebanyak 64%, sedangkan box system sebanyak 41,6%Kata kunci: Kanker servik, box system, brakiterapi, respon terapi, survival   
Co-Authors - Anggorowati Annastasia Ediati Ari Suwondo Bambang Cahyono Barirah, Barirah Deviana, Meli Dewi Puspitasari, Vannya Endang Mahati Endang Sri Lestari Hertanto Wahyu Subagio Hidayat, Syarief Thaufik Kurniawati, Erna Yovi Marpaung, Mona Galatia Martha Irene Kartasurya Mohammad Hakimi Sari Sudarmiati Sera, Agnescia Clarissa Sri Wahyuni Suhartono Suharyo Hadisaputro Susilani, Amalina Tri Teuku Mirza Iskandar, Teuku Mirza Yuni Purwati Yuniarti Yuniarti