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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sain Peternakan Indonesia Journal of Biomedicine and Translational Research Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Global Health Management Journal Journal of Nursing Care Berita Kedokteran Masyarakat Jurnal Info Kesehatan
Noor Pramono
Departement of Obsterics and Gynecology
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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COMBINATION OF POLYTHYLENE TEREFTALAT NESTING AND PRONE POSITION AT THE STANDARD BOX CARE TO THE VITAL SIGNS AND LENGTH OF STAY ON THE LOW BIRTH WEIGHT BABIES Deviana, Meli; Pramono, Noor; Suwondo, Ari
GHMJ (Global Health Management Journal) Vol 4, No 1 (2020): Online First
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-41269

Abstract

Background: The use of nesting and position prone facilitates Low Birth Weight Babies by conditioning it as in the mother's womb which aims to facilitate Low Birth Weight Babies in the development of physiological functions and achieve physiological function stability.Aims: This study aims to explain the effectiveness of design nesting with material polyethylene terephthalate and the position of prone with standard care using a box of baby warmers for the length of stay which is observed from the achievement of the stability of vital signs on LBW.Methods: This is a Quasi-Experimental Design study with non-equivalent control group design. The study population was all LBW treated in the Perinatal room with a sample of 36 LBW and consecutive sampling. This research was conducted in the Perinatal Room at RSUD RAA Soewondo Pati and RSUD Dr. R. Soetrasno Rembang. Statistical test for paired groups using Wilcoxon and for unpaired groups using Kruskall Wallis.Results: The combination of nesting polyethylene group with position prone achieved faster vital signs stability and shorter duration of treatment compared to the control group with p = 0.001 for temperature, respiration and oxygen saturation.Conclusions: The combination of polyethylene terftalat nesting and prone position is effective to reduce the duration of treatment duration, and may achieve the stability of vital signs of low birth weight infants. This intervention can be used as LBW care during hospital and home care. Keywords: Nesting, Position Prone, Polyethylene Tread, Length of Stay, Baby Vital Signs.
Polycystic Ovary Syndrome Markers and Mechanism Kurniawati, Erna Yovi; Pramono, Noor; Hidayat, Syarief Thaufik; Mahati, Endang
Syifa'Medika Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i1.7829

Abstract

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hormonal imbalances, metabolic dysregulation, and reproductive abnormalities. This study aims to elucidate the significance of PCOS markers and their mechanisms while outlining the methodology employed. A comprehensive literature review was conducted from 2020 to 2023 using databases like PubMed, ScienceDirect, EMBASE, and Google Scholar. Key search terms included "pathophysiology," "pathogenesis," "PCOS," "marker," and "biomarker," aligned with the PICOT criteria. After removing duplicates, articles underwent a two-phase screening process based on predefined inclusion criteria. Additionally, a marker mechanism flowchart was created using the Biorender application. Results highlighted the pivotal role of various markers in understanding PCOS pathophysiology and guiding clinical management. Anthropometric, visual, metabolic, inflammatory, endocrine, and oxidative stress markers were analyzed for their diagnostic, prognostic, and therapeutic implications in PCOS. The study underscores the importance of marker interactions in personalized PCOS management. Limitations in marker interpretation warrant further research to refine diagnostic accuracy and optimize therapeutic interventions. Integrating marker mechanisms enhances understanding of PCOS heterogeneity and informs targeted treatment approaches tailored to individual phenotypic variations.
Perceptions of primigravida and their husbands regarding the need for maternal-fetal attachment stimulation Purwati, Yuni; Pramono, Noor; Hakimi, Mohammad; Sudarmiati, Sari; Anggorowati, Anggorowati
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23913

Abstract

Prenatal class programs for primigravidas are important to improve fetal care behavior and reduce infant mortality. In prenatal classes, there is no maternal-fetal attachment stimulation education program which is important for improving maternal-fetal attachment and fetal well-being. The perceptions of pregnant women and their husbands regarding knowledge and experience of pregnancy as well as maternal-fetal attachment (MFA) stimulation are important for assessing the need for MFA educational materials. The research aimed to examine the perceptions of primigravidas and their husbands regarding pregnancy and MFA stimulation. Exploratory descriptive qualitative study method. Data were collected using in-depth interviews with 10 primigravidas and their husbands at the Community Health Center in Bantul, Yogyakarta, Indonesia, using an interview guide. Data analysis by condensing data, presenting data, and drawing conclusions, verbatim results of interviews are presented in coding, found categories, and themes. Four themes were produced: knowledge of pregnancy and fetal growth and development; concept of maternal-fetal attachment skills; management of pregnancy emotional management; and husband's support. The conclusion of this theme's findings underlies the development of maternal-fetal attachment educational materials in prenatal classes to prepare mothers for their role, and improve MFA and maternal-fetal health.
Factors associated with pregnancy-related anxiety: a health facility-based study Wahyuni, Sri; Pramono, Noor; Hadisaputro, Suharyo; Ediati, Annastasia
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.24327

Abstract

Pregnancy is a critical phase for human beings, which can lead to various mental health issues, including anxiety. It is important to recognize that pregnancy-related anxiety can increase over time and should be addressed. This study aimed to explore the multifactor of pregnancy-related anxiety during the first trimester. A cross-sectional health facility-based study was conducted in four Semarang, Central Java, Indonesia public health centers. A total of 129 pregnant women were involved and identified some exposures, such as socio-demographics, nausea and vomiting during pregnancy (NVP), emotion regulation, social support, and anxiety levels. The average age of participants was 27.3 years. Their anxiety level was moderate to severe (37.2%), and 62.8% were identified as having mild anxiety. This study suggests that pregnant women who lack social support (AOR=4.105; 1.824-9.237) and emotion dysregulation (AOR=2.749; 1.244-6.075) were identified as the risk factors of maternal anxiety during the first trimester. Being employed (AOR=0.410; 0.182-0.922) protects the high anxiety during pregnancy. This study suggests that the lack of social support, including social interaction most influences pregnant women’s mental well-being. Therefore, it may be helpful to establish an intervention plan that strengthens social support to improve maternal mental well-being.
Assasement and Experimental Procedure Polycystic Ovary Syndrome Rat Model: Review Kurniawati, Erna Yovi; Pramono, Noor; Hidayat, Syarief Thaufik; Mahati, Endang
Jurnal Sain Peternakan Indonesia Vol 18 No 4 (2023)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/jspi.id.18.4.242-256

Abstract

A complicated endocrine condition that affects many women worldwide is called polycystic ovarian syndrome, or PCOS. The use of rat models has greatly aided research on many facets of PCOS. In addition to discussing the parameters, evaluation techniques, and indicators pertinent to PCOS research, this study evaluates the standard circumstances of PCOS rat models. Our knowledge of PCOS has improved due to investigating endocrine, hormonal, inflammatory, oxidative stress, metabolic, genetic, and microbiota-related factors in these models. The results highlight how important it is to use PCOS rat models to understand the complexities of this illness and offer possible treatment avenues.
Mean the levels of 25(OH) D in the II trimester of pregnant women at Sleman, Indonesia Susilani, Amalina Tri; Subagio, Hertanto Wahyu; Pramono, Noor; Kartasurya, Martha Irene
BKM Public Health and Community Medicine PHS7 Accepted Abstracts
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: Pregnant women possess a high risk of suffering from a deficiency of vitamin D3. A deficiency of Vitamin D3 is associated with pregnancy-related complications, such as preterm birth, preeclampsia, gestational diabetes, and babies born small for gestational age. Furthermore, it creates a risk of infection and breathing problems when the baby is born, and affects the life of the child. Methods: A descriptive study was done and consisted of participants who met the following criteria: 20 - 35 years of age, BMI between 18.5-24.9, had a record of their last day of menstruation (HPHT). Informed consent was also obtained and signed by all the participants. Women who had histories of preeclampsia and eclampsia, bleeding, premature rupture of membranes, gemelli pregnancy, abortion, and immature births, and mothers with comorbidities such as heart, lung, liver, intestinal, bone, kidney, thyroid, and immunology diseases were excluded from the study. Examination of 25 (OH) D was done using Enzyme-Linked Immuno Sorbant Assay (ELISA) method with 1.5 ml of the sample which had been centrifuged and had its serum extracted. Results: The study began in July 2020 with a total of 80 pregnant women in their second trimester (TM II). The participants had an average height of 154.5 cm and body weight before pregnancy of 51.8 kg. The results obtained showed insufficient levels of 25 (OH) D levels in 72 (90%) participants and sufficient/normal levels in 8 (10%) participants. Conclusion: Most pregnant women at Sleman Indonesia had insufficient levels of 25 (OH) D.
Nausea and Vomiting of Pregnancy: Multiple Contributing Factors Wahyuni, Sri; Pramono, Noor; Hadisaputro, Suharyo; Ediati, Annastasia
JURNAL INFO KESEHATAN Vol 21 No 4 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss4.1388

Abstract

Nausea and vomiting are common conditions in earlier pregnancy. Some studies have suggested that nausea and vomiting during pregnancy (NVP) is caused by multiple factors, however, few studies assessed family support and psychological factors. The present study aimed to assess the prevalence of NVP and its contributing factors. A cross-sectional study was conducted in five Primary Health Centers in Semarang during August 2023. A total of 99 eligible pregnant women were included. A logistic regression was used to determine the significant contributing factors of NVP. The prevalence of moderate to severe and mild NVP was 71.7% and 28.3% respectively. Bivariate analysis indicated that gestational age and anxiety level significantly influence NVP (p-value <0.05). Women with greater gestational age (OR= 2.462; 0.954-6.356) and mild anxiety (OR=3.337; 1.240-8.982) were more likely to experience NVP during their pregnancy. Gestational of 12 weeks and mild anxiety are strongly associated with NVP. These findings highlight the crucial of psychological factors despite other health-related conditions.
Maternal Determinants of Preeclampsia Incidence in Arjawinangun Hospital, Cirebon District, West Java: A Case Study Nurjanah, Nunung; Pramono, Noor; -, Anggorowati; Soejoenoes, Ariawan
Journal of Nursing Care Vol 8, No 3 (2025): Journal of Nursing care
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jnc.v8i3.64167

Abstract

Most of these complications develop during pregnancy. The main complications accounting for 80% of maternal deaths are severe bleeding (mostly postpartum hemorrhage), infection (usually after delivery), high blood pressure during pregnancy (pre-eclampsia and eclampsia) and unsafe abortion. This was an analytic observational study with a case control design. The data taken were the medical records of patients diagnosed with preeclampsia from Januari to Desember 2024. The population of pregnant women at RSUD Arjawinangun, Cirebon was 2.780 pregnant women. The sample size was obtained by random sampling technique as many as 350 pregnant women in accordance with the inclusion and exclusion criteria determined for the study. The result that Age (p-value 0.001, OR 5.678), Parity (p-value 0.001, OR 2.606), Occupation (p-value 0.026, OR 2.053), Pregnancy distance (p-value 0.002, OR 2.005), Nutritional Status (p-value 0.001, OR 3.898), History of Preeclampsia (p-value 0.001, OR 14.462), MAP (p-value 0.001, OR 7.644). Age, Gravida, Interpregnancy interval, BMI, History of preeclampsia, MAP, occupation are factors contributing to the occurrence of preeclampsia in pregnant women at Arjawinangun Hospital, Cirebon Regency. Pregnant women with a history of preeclampsia have a 153.342 times higher chance of experiencing preeclampsia in their current pregnancy. Age, Gravida, Interpregnancy interval, BMI, History of preeclampsia, MAP, occupation are factors contributing to the occurrence of preeclampsia in pregnant women at Arjawinangun Hospital, Cirebon Regency.   
Low sEng Level in Preeclampsia with MFTHFR Gene Polymorphism Suggesting a Protective Factor Pramono, M. Besari Adi; Faradz, Sultana MH; Suhartono, Suhartono; Susanto, Hardhono; Rachmawati, Banundari; Pramono, Noor
Journal of Biomedicine and Translational Research Vol 11, No 3 (2025): December 2025
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v11i3.29375

Abstract

Background: Preeclampsia is one of the most serious complications of pregnancy and the leading cause of maternal and fetal mortality. Various studies have shown that Glutathione Peroxidase (GPx) deficiency and increased Soluble endoglin (sEng) level are consistently associated with the incidence of preeclampsia. Several studies also show the role of MTHFR A1298C and C677T gene polymorphisms in preeclampsia.Objective: This study investigated association between blood GPx, sEng levels, MTHFR A1298C and C677T gene polymorphisms in Preeclampsia.Methods: This analytic observational case-control study was conducted on 70 cases of preeclampsia and 70 controls. Blood GPx and sEng levels were measured using Enzyme Linked Immunosorbent Assay (ELISA). MTHFR A1298C and C677T gene polymorphism was genotyped using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). The data obtained were analyzed using the Mann-Whitney U test, chi-square test, and independent T-test.Results: There were no significant differences in GPx levels or MTHFR A1298C/C677T genotype distribution between groups. sEng levels were significantly higher in the preeclampsia group than controls (p=0.001). ROC analysis identified a cut-off of 7.75 ng/mL. Among preeclampsia patients, those with the MTHFR 1298AC/CC genotypes had lower sEng levels than wildtype (p=0.027), suggesting a potential protective effect. No association was found for C677T.Conclusion: We found no significant difference in GPx level, MTHFR A1298C and C677T gene polymorphism between preeclampsia and control group. Soluble endoglin (sEng) level in the preeclampsia group (mean: 11.0±5.22) were significantly different (p=0.001) compared to the control group (mean: 8.1±5.31). Increased level of sEng is associated with incidence of preeclampsia. A key finding in this study is the significantly lower sEng levels observed in preeclampsia patients carrying the MTHFR 1298AC and 1298CC alleles compared to the control group (p=0.027). This indicates a protective factor where in preeclampsia with MTHFR gene alleles 1298AC and 1298CC sEng levels are lower compared to wildtype.
Co-Authors - Anggorowati Annastasia Ediati Ari Suwondo Banundari Rachmawati Barirah, Barirah Deviana, Meli Endang Mahati Hardhono Susanto Hertanto Wahyu Subagio Hidayat, Syarief Thaufik Kurniawati, Erna Yovi M. Besari Adi Pramono, M. Besari Adi Martha Irene Kartasurya Mohammad Hakimi Nunung Nurjanah Sari Sudarmiati Soejoenoes, Ariawan Sri Wahyuni Suharyo Hadisaputro Sultana MH Faradz Susilani, Amalina Tri Yuni Purwati