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Potensi Ekstrak Daun Turi Merah (Sesbania grandiflora L. Pers) Sebagai Immunomodulator Pada Mencit (Mus musculus) Nifas yang Diinokulasi Streptococcus agalactiae Mardiana, Heppy Rina
Jurnal Pendidikan Tambusai Vol. 6 No. 1 (2022): April 2022
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.328 KB)

Streptococcus agalactiae merupakan salah satu bakteri yang berperan terhadap terjadinya infeksi post partum selain Staphylococcus aureus. Tujuan penelitian ini mengetahui potensi ekstrak daun turi merah sebagai immunomodulator terhadap Mencit (Mus musculus) nifas yang diinokulasi Streptococcus agalactiae.Terdapat 4 kelompok mencit nifas yaitu : satu kelompok kontrol, dan tiga kelompok perlakuan dengan 3 dosis. Pemberian ekstrak daun turi merah pada kelompok perlakuan 2 jam setelah pemberian bakteri melalui oral dengan 3 dosis. Pengukuran kadar sitokin IL 6 menggunakan metode ELISA. Analisis menggunakan uji Kruskal-Wallis didapatkan (p < 0,05) dan uji |Ri-Rj| 5%. Hasil penelitian menunjukkan bahwa penurunan kadar sitokin proinflamasi IL 6 secara signifikan pada kelompok perlakuan (P2) dengan dosis 250mg/kgBB dan (P3) dengan dosis 500mg/kgBB. Zat aktif pada daun turi merah (flavonoid) mempengaruhi makrofag untuk menurunkan sitokin proinflamasi.

THE EFFECT OF RED SESBANIA (SESBANIA GRANDIFLORA L.PERS) LEAVES EXTRACT ADMINISTRATION ON THE DECREASE OF LEUKOCYTE LEVEL IN POST-PARTUM MICE (MUS MUSCULUS) INFECTED WITH STREPTOCOCCUS AGALACTIAE HEPPY RINA MARDIANA; Surya Mustika Sari; YUFI ARIS LESTARI; ANIK SUPRIANI; NANIK NUR ROSYIDAH; TITIEK IDAYANTI; HERLINA HERLINA
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 2 No 01 (2018): IJNMS Volume 2 Issue 1, April 2018
Publisher : Bina Sehat Press. Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Introduction: Maternal Mortality Rate (MMR) is indicator of public health degree. The cause of maternal mortality is postpartum infection. Streptococcus agalactiae bacterium contributes to postpartum infection incidence through vaginal or reproductive organ injury. Infection incidence is characterized with the increased level of leukocyte. The treatment of post-partum infection is done by administering antibiotics. Red sesbania leaves contains active substance that can inhibit the microbial growth. Objective: This research aimed to find out the effect of red sesbania leaves extract administration as antimicrobial agent to decrease leukocyte level in post partum mice (Mus musculus) infected with Streptococcus agalactiae. Method: The method employed was true experimental one with post test control group design, by dividing postpartum mice into 4 groups: one control group and three treatment groups at doses of 125 mg/kgBW, 250 mg/kgBW, and 500 mg/kgBW. All 0-12 hour post partum mice were inoculated with Streptococcus agalactiae bacterium. The administration of 1 ml red sesbania leaves extract in treatment group was conducted 2 hours after the bacterial administration at doses of 125 mg/kgBW, 250 mg/kgBW, and 500 mg/kgBW. Result: The result of analysis shows p < 0.05, indicating that the decrease of leukocyte level in all treatment groups (P1, P2, P3). Conclusion: Red sesbania leaves extract has antimicrobial activity that can reduce leukocyte level, thereby can be used as an alternative therapy to decrease maternal mortality rate due to post-partum infectin. KEYWORDS Red sesbania leaves extract, postpartum mice, leukocyte level, Streptococcus agalactiae.

INFLUENCE OF DYSMENORRHEA GYMNASTIC ON MENSTRUAL PAIN TO 8TH GRADE STUDENTS OF SMPN 2 SOOKO DISTRICT MOJOKERTO Titiek Idayanti; Hartin Su'idah; Devi Kharismanda Haryanto; Surya Mustika Sari; Heppy Rina Mardiana; Vera Virgia
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 2 No 01 (2018): IJNMS Volume 2 Issue 1, April 2018
Publisher : Bina Sehat Press. Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Light exercises (gymnastics) are highly recommended to reduce dysmenorrhea but during this adolescent only use medical therapy drugs to reduce the pain felt. The purpose of this study to determine the effect of dismal gymnastics on menstrual pain in adolescent girls 8th grade of SMPN 2 Sooko Mojokerto regency. The research design is Pre-Experimental Design with Static Group Comparison approach. The research variables are dysmenorrhea gymnastic as independent variable and dysmenorrhea pain as the dependent variable. The study population is all students of 8th grade who experienced menstrual pain in SMPN 2 Sooko as many as 54 people. A sample of 48 students taken with cluster sampling technique. Data were collected with pain scale observation sheets, and the results were tested with the Wilcoxon test. The results of Wilcoxon test showed that there was the influence of discharging gymnastics on menstrual pain in 8th grade of SMPN 2 Sooko Mojokerto. which is indicated by Ï = 0,000 and Î± = 0,05 so that Ï <Î± then H0 is rejected and H1 is accepted. Gymnastics dysmenorrhea with several movements that can provide a sense of comfort and calm so that it can affect the response of pain experienced by respondents. Students are expected to apply dysmenorrhea gymnastics to be able to relieve the pain of dysmenorrhea pain experienced so that the pain experienced can be reduced and respondents not only rely on pharmacological drugs in reducing the pain experienced.

EFFECTIVENESS OF GREEN TEA FEEDING TO DECREASE CHOLESTEROLLIN HIPERCOLESTROL PATIENTS AT VILLAGE TUNGGAL PAGER DISTRICT PUNGGING MOJOKERTO REGENCY Anik Supriani; Nur Chasanah; Henny V Vidia Effendy; Surya Mustika Sari; Heppy Rina Mardiana; Tri Ayu Widiyaswari
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 2 No 01 (2018): IJNMS Volume 2 Issue 1, April 2018
Publisher : Bina Sehat Press. Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Cholesterol disease is commonly suffered by obese people but did not rule out skinny people can also experience it. Green tea is one method in the management of cholesterol reduction in non-pharmacology. Green tea has the benefit of lowering cholesterol. The purpose of this researcher to analyze the effectiveness of green tea to decrease cholesterol. The design of this study used pre-experiment with one group pre-test posttest. The population of 21 respondents using non-probability sampling with total sampling technique. The variables of this study were cholesterol first performed cholesterol assessment, independent variables Effectiveness of green tea and dependent variable decreased cholesterol levels. The results before the green tea were given most of the high cholesterol as many as 13 respondents (61.9%), after being given a green tea for one week most of the cholesterol to 13 respondents (61.9%). The Wilcoxon statistic test obtained a significant value of 0.005 and showed that there was a considerable effect of green tea on cholesterol reduction. The conclusion from the researchers is there is a significant effect of the effectiveness of green tea on changes in cholesterol levels. Cholesterol treatment performed twice a day morning and night regularly for one week. This research can also be applied in nursing care on respondents who experienced cholesterol and as well as prevention efforts cholesterol.

EDUKASI MANFAAT DAUN TURI MERAH (SESBANIA GRANDIFLORA L. PERS) UNTUK KESEHATAN REPRODUKSI PADA MASYARAKAT DESA SEDURI KECAMATAN MOJOSARI KABUPATEN MOJOKERTO Mardiana, Heppy Rina
PRIMA WIYATA HEALTH Vol 2 No 2 (2021): Prima Wiyata Health, Juli 2021
Publisher : LPPM STIKES HUSADA JOMBANG

Penyakit reproduksi disadari telah menjadi masalah kesehatan dunia yang cukup serius, dan perempuan lebih tinggi jumlah penderitanya dibanding laki-laki. Sebelum wanita terkena penyakit reproduksi, dibutuhkan upaya pencegahan lebih dini, salah satunya dengan makan makanan sehat yang kaya antioksidan. Hasil studi pendahuluan pada bulan Maret 2021 terhadap 10 wanita usia subur (WUS) Di Desa Seduri didapatkan bahwa semua Ibu (100%) tidak mengetahui tentang makanan kaya antioksidan dan cara mencegah penyakit reproduksi. Di samping itu, semua Ibu tersebut memiliki kebiasaan makan makanan yang tidak sehat karena sudah terbiasa dan rasanya enak. Tujuan program pengabdian masyarakat ini adalah untuk memberikan edukasi pada para Ibu tentang manfaat tanaman daun turi merah untuk kesehatan reproduksi. Sasaran audiens adalah tim penggerak PKK desa yang berperan sentral dalam kesehatan keluarga. Kegiatan diselenggarakan melalui ceramah, dan demonstrasi cara mengolah daun turi merah. Pre dan post test dalam bentuk kuesioner tentang tanaman antioksidan dan daun turi merah. Dari hasil tes diketahui pengetahuan peserta tentang tanaman daun turi merah yaitu cukup baik. Lebih dari 50% peserta belum mengetahui cara pengolahan daun turi merah yang tepat supaya tidak kehilangan bahan aktif. Kesimpulan program ini adalah terjadi peningkatan pemahaman peserta tentang tanaman daun turi merah untuk kesehatan reproduksi.

Potensi Ekstrak Daun Turi Merah (Sesbania grandiflora L. Pers) Sebagai Immunomodulator Pada Mencit (Mus musculus) Nifas yang Diinokulasi Streptococcus agalactiae Mardiana, Heppy Rina
Jurnal Pendidikan Tambusai Vol. 6 No. 1 (2022): 2022
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v6i1.3104

Streptococcus agalactiae merupakan salah satu bakteri yang berperan terhadap terjadinya infeksi post partum selain Staphylococcus aureus. Tujuan penelitian ini mengetahui potensi ekstrak daun turi merah sebagai immunomodulator terhadap Mencit (Mus musculus) nifas yang diinokulasi Streptococcus agalactiae.Terdapat 4 kelompok mencit nifas yaitu : satu kelompok kontrol, dan tiga kelompok perlakuan dengan 3 dosis. Pemberian ekstrak daun turi merah pada kelompok perlakuan 2 jam setelah pemberian bakteri melalui oral dengan 3 dosis. Pengukuran kadar sitokin IL 6 menggunakan metode ELISA. Analisis menggunakan uji Kruskal-Wallis didapatkan (p < 0,05) dan uji |Ri-Rj| 5%. Hasil penelitian menunjukkan bahwa penurunan kadar sitokin proinflamasi IL 6 secara signifikan pada kelompok perlakuan (P2) dengan dosis 250mg/kgBB dan (P3) dengan dosis 500mg/kgBB. Zat aktif pada daun turi merah (flavonoid) mempengaruhi makrofag untuk menurunkan sitokin proinflamasi.

The Effect Of Giving Calcium As An Effort To Prevent Preeclampsia: A Literature Review Cahyani, Desy Dwi Cahyani; Ayundasari, Ega; Mardiana, Heppy Rina; Sunaeni, Sunaeni; Irawati , Irawati; Mulyati, Mulyati
An Idea Nursing Journal Vol. 2 No. 02 (2023)
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/inj.v2i02.194

Preeclampsia is a pregnancy disorder accompanied by hypertension and proteinuria. Efforts to prevent preeclampsia can be made with medical prevention, namely, meeting the calcium needs of pregnant women. This research aims to determine the effect of givingcalcium to prevent preeclampsia. The method used in the literature review is a systematic mapping study obtained from 3 databases, namely Pubmed, Garuda, and Google Scholar, using inclusion and exclusion criteria. Key term used in searching literature: "Calcium for prevention of preeclampsia." from 10 journals, it was found that the correct dose of calcium and timing of giving calcium to pregnant women was found and that calcium had an effect on preventing preeclampsia. Data analysis techniques use Synthesize or compare. Conclusion: Mothers are advised to consume calcium because it can lower blood pressure. By reducing blood pressure in pregnant women, calcium can prevent the occurrence of preeclampsia, especially in pregnant women who have hypertension or a history of preeclampsia.

PENGARUH AUDIO MUROTTAL SURAH AR-RAHMAN TERHADAP PENGURANGAN MUAL MUNTAH PADA IBU DENGAN HIPEREMESIS GRAVIDARUM Heppy Rina Mardiana; Ratih Kusuma Wardhani; Duhita Dyah Apsari; Sheilla Tania Marcellina
EZRA SCIENCE BULLETIN Vol. 3 No. 1 (2025): January-June 2025
Publisher : Kirana Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58526/ezrasciencebulletin.v3i1.329

Hiperemesis gravidarum merupakan mual muntah berlebihan yang dapat terjadi pada Ibu Hamil, dan pada umumnya terjadi di trimester I (Pillay, 2016 dan Margareth, 2019). Tujuan penelitian yaitu mengetahui pengaruh audio Murottal Surah Ar-Rahman terhadap pengurangan mual muntah pada Ibu dengan hiperemesis gravidarum di Puskesmas Laren Kabupaten Lamongan. Jenis penelitian yaitu kuantitatif dengan desain eksperimen yaitu Pra Experimental Design. Populasinya seluruh ibu hamil di Puskesmas Laren Kabupaten Lamongan periode bulan Januari – Maret 2025 sebanyak 100 responden, sampel sebanyak 30 responden dengan teknik sampling Purposive Sampling. Instrumen penelitian menggunakan lembar kuesioner Numeric Rating Scale (NRS). Uji statistik dengan Paired t-test didapatkan nilai Sig. (2-tailed) yaitu 0,003 (< 0,05), berarti ada pengaruh audio murottal Al-Qur’an Surah Ar-Rahman terhadap pengurangan mual muntah. Ibu Hamil hendaknya memiliki sikap positif terhadap kehamilannya yang dapat membantu meningkatkan kesehatannya.

The Role of Health Cadres and Pregnant Women's Visits in Integrated Primary Service Post in Sidorahayu Village, Wagir District, Malang Regency Yuliawati, Dwi; Wardhani, Ratih Kusuma; Mardiana, Heppy Rina
Asian Journal of Healthcare Analytics Vol. 4 No. 1 (2025): May 2025
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v4i1.14451

Primary Service Transformation of health services to the community is done to enhancement and reinforcement promotion, prevention for healthy in the life cycle. Health problems in mothers and babies are great, so attempts are be required to strengthen primary health services. The purpose of this study was to determine the relationship between the role of health cadres and visits by pregnant women at the Integrated Primary Service Post in Sidorahayu Village. This study presented an analytical cross-sectional study utilizing data from a questionnaire was conducted between November until December 2024. Samples were 25 pregnant woman. In the study, there is a relationship between the role of cadres and the compliance of pregnant women in visiting the Integrated Primary Service Post.

PENGARUH KELAS PARENTING TERHADAP KESIAPAN PASANGAN CALON PENGANTIN MENJADI ORANG TUA DI KUA KECAMATAN KEDUNGKANDANG KOTA MALANG Nabila Irsyahdianty; Heppy Rina Mardiana; Ni Wayan Dwi Rosmalawati; Dwi Yuliawati
EZRA SCIENCE BULLETIN Vol. 3 No. 2 (2025): July-December 2025
Publisher : Kirana Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58526/ezrasciencebulletin.v3i2.446

Kesiapan menjadi orang tua merupakan aspek penting bagi pasangan calon pengantin, namun masih banyak yang memasuki pernikahan tanpa pengetahuan dan keterampilan memadai untuk mengasuh anak. Penelitian ini bertujuan menganalisis pengaruh kelas parenting terhadap kesiapan pasangan calon pengantin di KUA Kecamatan Kedungkandang Kota Malang. Desain penelitian menggunakan pre-eksperimental dengan pendekatan one group pre-test and post-test. Sampel penelitian adalah 24 pasangan calon pengantin yang dipilih melalui teknik accidental sampling pada periode 7 Juli–7 Agustus 2025 sesuai kriteria inklusi. Instrumen yang digunakan berupa kuesioner pre-test dan post-test. Hasil penelitian menunjukkan adanya peningkatan kesiapan responden sebesar 45,83% setelah intervensi. Uji Wilcoxon signed-rank test menghasilkan p-value 0,029 (<0,05), yang berarti terdapat pengaruh signifikan kelas parenting terhadap kesiapan menjadi orang tua. Temuan ini menegaskan bahwa kelas parenting berpotensi diterapkan secara berkelanjutan di KUA sebagai strategi preventif dalam menghadapi permasalahan keluarga dan pengasuhan anak.

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