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All Journal Medicina E-Jurnal Medika Udayana Sari Pediatri Paediatrica Indonesiana ISM (Intisari Sains Medis) : Jurnal Kedokteran
NP Veny Kartika Yantie
Department Of Child Health, Faculty Of Medicine, Universitas Udayana, Integrated Cardiac Service, Sanglah Hospital, Denpasar
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology

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Journal : Medicina

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INHIBITOR IN HEMOPHILIA K Yantie, Veny; K, Ariawati
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina

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Abstract

Hemophilia is an X-linked recessive disorder which is believed to affect approximately one in 5000-10.000 male birth. An inhibitor  is a type of antibody. In hemophilia patients type A, B, and C are directly destroy factor VII, IX, and XI. The incidence of antibody development in hemophilia A is between 20% and 40%, hemophilia B inhibitors only 1 to 6 %. The presence of an inhibitor is usually confirmed using a specific blood test called the Bethesda inhibitor assay. The treatment of hemophilic bleeding in a person with an inhibitor can be a challenging experience. Patients hemophilia with inhibitor have poor prognostic. (MEDICINA 2012;43:31-36).
Co-Authors Anak Agung Ngurah Ketut Putra Widnyana Bagus Ngurah Putu Arhana Chaliza Adnan Dewi, Luh G.A.P. Eka Gunawijaya Eko Kristanto Kunta Adjie Elizabeth Joan Salim Gusti Ayu Putu Nilawati Hendra Santoso Hendra Santoso I Gde Raka Widiana I Gusti Ayu Made Dwisri Okadharma I Gusti Lanang Sidiartha I Gusti Ngurah Sanjaya Putra I Made Arimbawa I Made Kardana I Nyoman Budi Hartawan I Wayan Dharma Artana I Wayan Gustawan Ida Bagus Subanada IGN Sanjaya Jusuf Rachmat Karmelia Kumala Ketut Ariawati Ketut Dewi Kumara Wati Ketut Suarta Ketut Suarta Komang Ayu Witarini Luh Gede Yuliadewi NS Made Gede Dwi Lingga Utama Mulyadi M. Djer Najib Advan Ni Made Ayu Agustini Ni Nyoman Metriani Nesa Ni Putu Wirantari Purnomo Suryantoro Putu Diah Pratiwi