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All Journal FITOFARMAKA: Jurnal Ilmiah Farmasi JHTS Jurnal Ilmiah Dr. Aloei Saboe Journal of Hulonthalo Service Society
Rini Daud Supu
Universitas Bina Mandiri Gorontalo
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ASSOCIATION BETWEEN OBESITY AND SERUM URIC ACID LEVELS AMONG COMMUNITY RESIDENTS IN THE CATCHMENT AREA OF THE KOTA TIMUR COMMUNITY HEALTH CENTER, GORONTALO CITY Aprianingsih R. Djana; Diah Astini Paramita; Rini Daud Supu
Jurnal Ilmiah dr. Aloei Saboe Vol. 5 No. 2 (2025): Jurnal Ilmiah dr. Aloei Saboe
Publisher : LP2M Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47918/3xra2w61

Abstract

Obesity is a major public health problem associated with metabolic disorders, including hyperuricemia. Excess adiposity may increase serum uric acid levels through insulin resistance and impaired renal urate excretion. However, evidence from Indonesian primary healthcare settings remains limited. This study aimed to determine the association between obesity and serum uric acid levels among community residents in the catchment area of the Kota Timur Community Health Center, Gorontalo City. A quantitative analytical observational study with a cross-sectional design was conducted among 15 obese respondents selected using purposive sampling. Body Mass Index (BMI) was calculated from anthropometric measurements, while serum uric acid levels were measured using capillary blood samples with a Family Dr. Uric Acid Meter. Data were analyzed descriptively, and the association between BMI and serum uric acid levels was examined using the Spearman rank correlation test. Most respondents were female (53.3%) and aged 40–45 years (33.3%). Abnormal serum uric acid levels were found in 53.3% of respondents. The Spearman rank correlation test showed no significant association between obesity and serum uric acid levels (p = 0.592). Obesity, as measured by BMI, was not significantly associated with serum uric acid levels among obese community residents. Further studies with larger sample sizes and additional metabolic and lifestyle variables are needed to clarify this relationship.
The Effectiveness of Soursop Fruit Extract (Annona Muricata L) Against Uric Acid Levels in Male White Rats (Rattus Novergicus) Feronika Bakari; Titin Dunggio; Rini Daud Supu
Jurnal Ilmiah dr. Aloei Saboe Vol. 1 No. 1 (2021): Jurnal Ilmiah dr. Aloei Saboe
Publisher : LP2M Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47918/jias.v8i1.327

Abstract

This study aims to determine whether there is a therapeutic effect on soursop (Annona Muricata L) juice in reducing uric acid levels in male white rats (Rattusnovergicus) and to determine what dose of bay leaf extract (Syzyzgiumpolyanthum) is effective in reducing acidity levels. veins in male white rats (Rattusnovergicus). The method in this study used a laboratory experiment with a post-test only control group design. The treatment groups were group I (negative control), group II (90 ml soursop juice), group III (180 ml soursop juice), group IV (soursop juice 270 ml). The results showed that soursop juice (Annona Muricata L) was positive for polyphenolic compounds. Statistical analysis of the data by KruskalWalis that 0.280 or > 0.05 means that there is a significant difference between uric acid levels before administration of soursop juice and uric acid levels after providing juice soursop fruit and continued with Duncan's analysis to see the difference in the effective dose.
Co-Authors Adnan Malaha Ajeng Diantini, Ajeng Aprianingsih R. Djana Diah Astini Paramita Dunggio, Titin Dwi Audia Hassan Feronika Bakari Jutti Levita Multiani S Latif Novendra Puluhulawa Noviyanti I. Panu Nurul Pratiwi Sompah Pidyastuti Pakaya Rifka Anggraini Anggai Sarini Pani Syam S. Kumaji Widya Salandri Kisman Wiharsri