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Test the Effectiveness of Bay Leaf Extract (Syzygium Polyanthum) in Lowering Uric Acid Levels in Male White Rats (Rattus Novergicus) Lila Muliani; Gita Puspita; Rifka Anggraini Anggai
Journal of Health, Technology and Science (JHTS) Vol. 2 No. 3 (2021): Journal of Health, Technology and Science (JHTS)
Publisher : LPPM Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.791 KB) | DOI: 10.47918/jhts.v2i3.276

Abstract

This study aims to determine whether there is a therapeutic effect on bay leaf extract (Syzygium polyanthum) in reducing uric acid levels in male white rats (Rattus novergicus) and to determine what dose of bay leaf extract (Syzyzgium polyanthum) is effective in reducing uric acid levels in male white rat (Rattus novergicus). The method in this study used Laboratory Experiments with Pretest-Posttest Control Group Design, the treatment groups were group I (negative control), group II (positive control), group III (bay leaf extract 0.4581 g), group IV (extract bay leaf 0.8181 g), and group V (bay leaf extract 1.1781 g). The results showed that bay leaf extract (Syzygium polyhantum) was positive for flavonoid compounds. Statistical data analysis by Kruskal Walis showed that 0.003 p significance value 0.005 means that there is a significant difference between uric acid levels before administration of bay leaf extract and uric acid levels after administration of bay leaf extract and continued with Duncan's analysis to see differences in effective doses.
EFEKTIVITAS GETAH JARAK PAGAR (Jatropha curcas) Sebagai sediaan Gel Penyembuh Luka Bakar Nurul Pratiwi Sompah; Rini Daud Supu; Rifka Anggraini Anggai
Journal of Health, Technology and Science (JHTS) Vol. 3 No. 3 (2022): Journal of Health, Technology and Science (JHTS)
Publisher : LPPM Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47918/jhts.v3i3.846

Abstract

This study aims to determine the formulation of jatropha curcas gel preparations as a burn healer, to determine the characteristics and physical properties of jatropha curcas gel preparations, and to determine theeffectiveness ofjatropha curcas gel as a burn healer. The method in this study used an experimental method with five treatments. The treatments are: P1 (4% sap), P2 (8% sap), P3 (16% sap), P4 (Negative control), and P5 (Positive Control). The results showed that the formulation of jatropha curcas gel positively contained saponin compounds that had a burn healing effect in male white rats (Rattus novergicus). Thejatropha curcas gel formulation has been shown to have a healing effect on burns of male white rats (Rattus novergicus) with a concentration of 16% providing the best healing effect with the occurrence of 100% healing (wound closure) on the third day, followed by a concentration of 8% healing (wound closure) 100% occurring on the sixth day, and a 4% concentration of 100% healing (wound closure) occurring on the ninth day.
The Use of Corn Cob and Leaf Waste (Zea mays L.) as Herbal Support for Malaria Prevention: A Social–Humanities Approach Based on Laboratory Evidence Uno, Wiwit Zuriati; Dian Pratiwi Iman; Rifka Anggraini Anggai; Mahdalena Sy Pakaya; Sri Manovita Pateda
Qoumun: Jurnal Pengabdian Masyarakat Vol 1 No 2 (2025): Qoumun: Journal of Social and Humanities
Publisher : Cv. Kayaswara

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Abstract

Corn cobs and corn leaves (Zea mays L.) are abundant agricultural wastes with potential bioactive value. This study aimed to evaluate the extraction efficiency, phytochemical profile, and antioxidant activity of corn cob and corn leaf extracts obtained using solvents of different polarities, and to assess their relevance as supportive herbal resources for health promotion. Samples were extracted using ethanol, acetone, and n-hexane, followed by phytochemical screening and antioxidant evaluation using the DPPH method. The results demonstrated that ethanol extracts produced the highest yields and exhibited very strong antioxidant activity, indicated by low IC₅₀ values. These findings suggest that polar phytochemicals, particularly phenolic and flavonoid compounds, are the main contributors to the antioxidant potential of corn waste materials. Overall, this study provides scientific evidence supporting the valorization of corn agricultural waste as a sustainable source of antioxidant-rich herbal materials with potential relevance for oxidative stress management.
Antioxidant Activity Evaluation Of Catfish (Clarias Sp.) Collagen Extract Using DPPH And ABTS Methods Faramita Hiola; Uno, Wiwit Zuriati; Fika Nuzul Ramadhan; Rifka Anggraini Anggai; Cahniar Djamil
Qoumun: Jurnal Pengabdian Masyarakat Vol 1 No 2 (2025): Qoumun: Journal of Social and Humanities
Publisher : Cv. Kayaswara

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Abstract

This study aimed to evaluate the antioxidant activity of collagen extracted from catfish (Clarias sp.) using DPPH and ABTS assays. The research procedures included sample preparation, collagen extraction using an acid-based method, and antioxidant analysis at concentrations ranging from 20–100 ppm. The degree of hydrolysis (DH) was measured to determine the effectiveness of Alkalase in producing bioactive peptides. The results showed that higher enzyme concentrations led to increased DH, with the highest value of 62.42% obtained at 3% Alkalase. Antioxidant activity increased with sample concentration, with maximum inhibition values of 78.57% (DPPH) and 85.00% (ABTS) at 100 ppm. The ABTS assay exhibited higher sensitivity than DPPH. These findings indicate that catfish collagen has strong potential as a safe and natural antioxidant source suitable for further development in food, pharmaceutical, and cosmetic applications.