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All Journal Jurnal Kedokteran Syiah Kuala Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Implementa Husada Narra J Prosiding Seminar Nasional Biologi, Teknologi dan Kependidikan (Biotik) Jurnal Ilmu Medis Indonesia Prosiding Seminar Nasional Universitas Serambi Mekkah
Hilwah Nora
Fakultas Kedokteran Universitas Syiah Kuala/RSUD Dr. Zainoel Abidin
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Comparison of postthawing sperm motility recovery between cryopreserved with and without cryoprotective agent using 4 different cryopreservationmethods Irwan Taufiqur Rachman, Hilwah Nora Shofwal Widad
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.206 KB)

Abstract

Frozen-thawed human spermatozoa are routinely used for many assisted reproduction program.However, cryopreserved spermatozoa was reported to yield lower pregnancy rates compared tofresh semen in both intra uterine inseminations and in vitro fertilization/intracytoplasmic sperminjection (IVF/ICSI) due to the reduction of sperm motility and viability induced by cryopreservationprocedures. This study was aimed to evaluate the influence of cryoprotective agent (CPA) andcryopreservation methods on human sperm motility. This was a quasi experimental study. Thirtyseven normozoospermic semen samples collected in Permata Hati Infertility Clinics of Dr. SardjitoGeneral Hospital, Yogyakarta were recruited. Four different cryopreservation methods were appliedusing and without CPA (TEST-yolk buffer). In simple two steps freezing, cryostraw were graduallyfrozen from 8 to -4°C. In simple graduated freezing, cryostraus were directly frozen at -4°C. Invapor phase freezing method, the samples in cryostraw were placed 1 cm above liquid nitrogen.In the last method, the samples were directly submerged into liquid nitrogen. Thawing wasconducted by incubation at 37°C for 5 minutes. The sperm motility recovery after cryopreservationin the 4 different cryopreservation methods was evaluated and analyzed by analysis of variance(ANOVA). The fresh sperm motility before cryopreservation was 52.9 ± 4.50%. The recovery ofmotile sperms was 17.00 ± 7.83%, 20.96 ± 5.81%, 15.06 ± 8.55% and 15.68 ± 8.3%, whenusing CPA and 5.63 ± 4.63%, 5.47 ± 3.95%, 4.45 ± 4.46% and 6.08 ± 5.06% when withoutCPA following direct plunge to liquid nitrogen freezing, vapor liquid nitrogen freezing, simplegraduated freezing and simple 2-steps freezing, respectively. Among methods using CPA, thevapor phase method resulted in highest sperm motility recovery. In methods without CPA, nosignificant difference of sperm motility recovery was observed among the 4 differentcryopreservation methods. In conclusion, the use of CPA for cryopreservation improves spermmotility recovery.
MANAJEMEN AKTIF PERSALINAN KALA TIGA Hilwah Nora
Jurnal Kedokteran Syiah Kuala Vol 12, No 3 (2012): Volume 12 Nomor 3 Desember 2012
Publisher : Universitas Syiah Kuala

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Abstract

Abstrak. Perdarahan pasca persalinan (PPP) sampai saat ini masih merupakan penyebab utama kematian ibu di seluruh dunia. Sebagian besar kasus PPP terjadi selama persalinan kala tiga. Pada masa sebelumnya, kala tiga (pengeluaran plasenta) ditangani secara pasif dengan menunggu tanda-tanda lepasnya plasenta tanpa penggunaan uterotonika ataupun penegangan tali pusat terkendali. Dalam manajemen aktif, plasenta dilahirkan secara aktif dengan memberikan oksitosin 10 IU segera setelah bayi lahir, melakukan penegangan tali pusat terkendali (controlled-cord traction) dan masase uterus setelah pelepasan plasenta. Strategi ini diyakini akan menurunkan perdarahan pasca persalinan dan mempersingkat kala tiga.Tulisan ini bertujuan untuk membandingkan dua manajemen dalam menangani persalinan kala tiga dengan hasil akhir berupa penurunan kejadian perdarahan pasca persalinan.Abstract. Postpartum hemorrhage is one of the most common causes of maternal mortality and morbidity worldwide. Most of postpartum hemorrhage cases occurred   in the third stage of labor. In the old days the third stage of labor manage expectantly or physiologic management consists of delivery of the placenta without the use of uterotonic agents, cord clamping, or cord traction. Active management generally consists administration of a prophylactic oxytocin 10 IU up on delivery of the baby followed by controlled cord traction of umbilical cord, and uterine massege afterward. This strategy will decrease postpartum hemorrhage and shorten third stage. This paper try to compare active versus expectant management of the third stage of labor in reducing post partum hemorrhage.
TWIN TWIN TRANSFUSION SYNDROME Hilwah Nora
Jurnal Kedokteran Syiah Kuala Vol 13, No 2 (2013): Volume 13 Nomor 2 Agustus 2013
Publisher : Universitas Syiah Kuala

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Abstract

Abstrak. Twin-twin transfusion syndrome (TTTS) adalah suatu komplikasi dari kehamilan multipel monokorion yang berisiko tinggi menyebabkan kematian fetal/neonatus, terutama pada janin usia belum mampu hidup  dan bila janin berhasil hidup maka janin tersebut berisiko mengalami gangguan jantung, syaraf dan mental. Anastomosis pembuluh darah antar janin berperan penting pada patofisologi terjadinya TTTS. Darah ditransfusikan secara tidak seimbang antara satu janin (donor) dengan janin yang lain (resipien). Transfusi ini menyebabkan penurunan volume darah janin donor. Hal ini mengakibatkan pertumbuhan janin donor menjadi terhambat. Sedangkan janin resipien mendapat darah yang berlebihan sehingga bias mengakibatkan gagal jantung. Abstract. Twin-twin transfusion syndrome (TTTS) is one of the most serious complications of monochorionic multiple gestations. It is associated with a high risk of fetal/neonatal mortality, especially in previable gestations, and fetuses who survive are at risk of severe cardiac, neurologic, and developmental disorders. Placental intertwin vascular anastomoses play a key role in the pathophysiology of TTTS. Blood can be transfused disproportionately from one twin (the donor) to the other twin (the resipient). The transfusion cause the donor twin to have decreased blood volume. This in turn leads to slower than normal growth than its co-twin. The resipien twins become overloaded with blood. This excess blood puts a strain on this baby’s heart to the point that it may develop heart failure. 
PENGGUNAAN KONDOM KATETER UNTUK MENGATASI PERDARAHAN PASCA PERSALINAN PRIMER Hilwah Nora
Jurnal Kedokteran Syiah Kuala Vol 13, No 1 (2013): Volume 13 Nomor 1 April 2013
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v13i1.3433

Abstract

Abstrak. Perdarahan pasca persalinan sampai saat ini masih merupakan penyebab utama morbiditas dan mortalitas maternal baik di negara maju maupun di negara berkembang, termasuk Indonesia. Kejadian perdarahan pasca persalinan merupakan kondisi kegawatan yang membutuhkan penanganan segera agar tidak terjadi komplikasi yang tidak diinginkan. Ketika perdarahan pasca persalinan tidak bisa diatasi dengan pemberian uterotonika dan kuretase, maka tindakan selanjutnya adalah laparotomi sampai  dengan histerektomi.  Adanya morbiditas operasi dan keinginan untuk tetap mempertahankan fertilitas memunculkan mode terapi baru yaitu Kondom kateter.  Kondom kateter mudah didapatkan, tidak mahal dan bisa dilakukan di kamar bersalin sebagai alat untuk menghentikan perdarahan pasca persalinan yang disebabkan oleh atonia uteri Abstract. Postpartum hemorrhage is one of the major causes of maternal mortality both in developed and developing countries, including Indonesia. Post partum hemorrhage is a serious condition which required an urgent treatment to avoid undesirable complication. Historically, when uterine bleeding persists after administration of uterotonics and curettage, operative must be considered including hysterectomy. Morbidity of these surgeries and the desire to preserve fertility has led to the development of new therapies such as balloon tamponade. Balloon tamponade is a readily available, inexpensive procedure that can be performed in the delivery room as a therapy for postpartum hemorrhage due to uterine atonia.
The uterine rupture and bladder rupture on a pregnant mother with previous cesarean section after partum management on midwife Dewi Karlina Rusly; Hilwah Nora; Kartini Hasballah
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 3, No 1 (2013): Life Sciences
Publisher : Syiah Kuala University

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Abstract

A-case report about the process and impact of the vaginal birth after section caesarean in rural on a pregnant woman who has previous cesarean. This is the case of Mrs H, 30 years old in aterm gestational age with singleton intra partum fetal death, previous cesarean section, with suspected uterine rupture. She wasadmitted to RSUZA hospital due to unprogress labour, sent from midwife after failed of labour. In the hospital the catether was inserted and we found hematuria. She had been control for pregnancy in the hospital ofmother and baby for two times and the last 2 weeks was said the baby still in good condition. She was had the previous cesarean 5 years ago on second pregnancy due to unprogress labour and the incision was transversal,and also had the extraction vaccum history for delivered the first pregnancy. She already get information to delivered this third baby in the hospital, but she was coming to midwife due to contraction, and the orificium uretra extrenum was opened 8 cm, so the midwife try to delivered the baby for 1 hour, and because failed, the midwife sent to the hospital. After 3 hours, she was administered to the hospital the opened of orificium uteri was 10 cm and we found hematuria. During the way she was transferring to hospital she feels the movement of the baby was lost. When she administered in hospital the blood pressure was 100/70 mmHg, with the heart rate 100 times/ minute. She was complaints pain in the previous cesarean scar 3 hours later, and lost of fetalmovement since 1 hours ago. On ultrasound examination there was intrapartum fetal death. We decided to do laparotomy exploration due to suspected uterine rupture. On the operation we found 200 cc blood clot inside the layer of peritoneum, and after the peritoneum was cleaned and opened we could see the upper of the fetal head out side the uterus which intrapartum fetal death, with the large uterine rupture along the previous cesarean incision about 12 cm length. We also found the ballon of folley catheter outside the bladder, so weconfirm to urology and also found there was a bladder rupture grade IV with 14 cm lengths on the posterior bladder. After delivered the baby, The uronologist did repair bladder rupture and the bladder was inserted the spolling folley catheter with NaCl 0.9% from the upper bladder for maintenance the drainage of the bladder so it keep clean during in the ward and the folley cateter also inserted from the uretra. The procedure was continued with the obstetrician to do repairation of the uterine rupture. In the ward she was hospitalized for 14 days to maintain the bladder. From this case, we would like to assess the patophysiology of uterine rupture and bladder rupture which cause the mortality and morbidity of mother and baby. The uterine rupture has correlation withlate and false of management of delivery which result in intra partum fetal death and bladder rupture that was explained in this paper.
Comparison of postthawing sperm motility recovery between cryopreserved with and without cryoprotective agent using 4 different cryopreservationmethods Hilwah Nora Shofwal Widad Irwan Taufiqur Rachman
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.206 KB)

Abstract

Frozen-thawed human spermatozoa are routinely used for many assisted reproduction program.However, cryopreserved spermatozoa was reported to yield lower pregnancy rates compared tofresh semen in both intra uterine inseminations and in vitro fertilization/intracytoplasmic sperminjection (IVF/ICSI) due to the reduction of sperm motility and viability induced by cryopreservationprocedures. This study was aimed to evaluate the influence of cryoprotective agent (CPA) andcryopreservation methods on human sperm motility. This was a quasi experimental study. Thirtyseven normozoospermic semen samples collected in Permata Hati Infertility Clinics of Dr. SardjitoGeneral Hospital, Yogyakarta were recruited. Four different cryopreservation methods were appliedusing and without CPA (TEST-yolk buffer). In simple two steps freezing, cryostraw were graduallyfrozen from 8 to -4°C. In simple graduated freezing, cryostraus were directly frozen at -4°C. Invapor phase freezing method, the samples in cryostraw were placed 1 cm above liquid nitrogen.In the last method, the samples were directly submerged into liquid nitrogen. Thawing wasconducted by incubation at 37°C for 5 minutes. The sperm motility recovery after cryopreservationin the 4 different cryopreservation methods was evaluated and analyzed by analysis of variance(ANOVA). The fresh sperm motility before cryopreservation was 52.9 ± 4.50%. The recovery ofmotile sperms was 17.00 ± 7.83%, 20.96 ± 5.81%, 15.06 ± 8.55% and 15.68 ± 8.3%, whenusing CPA and 5.63 ± 4.63%, 5.47 ± 3.95%, 4.45 ± 4.46% and 6.08 ± 5.06% when withoutCPA following direct plunge to liquid nitrogen freezing, vapor liquid nitrogen freezing, simplegraduated freezing and simple 2-steps freezing, respectively. Among methods using CPA, thevapor phase method resulted in highest sperm motility recovery. In methods without CPA, nosignificant difference of sperm motility recovery was observed among the 4 differentcryopreservation methods. In conclusion, the use of CPA for cryopreservation improves spermmotility recovery.
Interaction of Physical Activity and Body Mass Index with Age at Menarche : Interaksi Aktivitas Fisik dan Indeks Massa Tubuh dengan Usia Menarche Filsa P. Anwar; Hilwah Nora; Muhammad Ridwan
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1498

Abstract

Objective: To investigate the interaction of physical activity and body mass index with age at menarche in Babun Najah Junior High School.Methods: This was a cross sectional study. The sampling technique in this study is non-probability sampling by a total sampling.Results: The results of the study were processed using the Chi-Square statistical test on 142 samples, obtained p-value = 0.748 (p>0.05) for the relationship between physical activity and age at menarche, p-value = 0.048 (p<0.05) for relationship between body mass index with age at menarche, and p-value > 0.05 for the interaction of physical activity and body mass index with age at menarche.Conclusions: There is no interaction of physical activity and body mass index with age at menarche in Babun Najah Junior High School.Keywords: body mass index, interaction, menarche age, physical activity. Abstrak Tujuan: Mengetahui interaksi aktivitas fisik dan indeks massa tubuh dengan usia menarche di Madrasah Tsanawiyah Swasta Babun Najah.Metode: Jenis penelitian ini adalah observasional analitik dengan desain penelitian potong lintang. Teknik pengambilan sampel dalam penelitian ini adalah pengambilan sampel non probabilitas dengan metode total sampling.Hasil: Terdapat hubungan antara indeks massa tubuh dengan usia menarche (p-value = 0,048) , tidak terdapat hubungan antara aktivitas fisik dengan usia menarche (p-value = 0,784) serta tidak terdapat interaksi antara aktivitas fisik dan indeks massa tubuh dengan usia menarche (p-value > 0,05).Kesimpulan: Tidak terdapat interaksi aktivitas fisik dan indeks massa tubuh dengan usia menarche di Madrasah Tsanawiyah Swasta Babun Najah.Kata kunci: aktivitas fisik, indeks massa tubuh, , interaksi, usia menarche
Hiploplasia Uterus dengan Amenorea Primer pada Sindroma Turner: Laporan Kasus Rajuddin Rajuddin; Sarjani Sarjani; Hilwah Nora
JURNAL IMPLEMENTA HUSADA Vol 2, No 2 (2021)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v2i2.10133

Abstract

Amenorea merupakan kondisi yang ditandai dengan ketidakadaan periode[PS1] [PS2]  menstruasi pada perempuan usia reproduksi. Kondisi ini terjadi akibat adanya kegagalan perkembangan alat reproduksi seperti ketidakadaan rahim, kegagalan ovarium serta anomali urogenital seperti kelainan duktus Mullerian. Diagnosis yang akurat sangat menentukan manajemen yang tepat dan optimal dalam penatalaksanaan. Laporan kasus ini bertujuan untuk menjelaskan mengenai pendekatan diagnostik serta tatalaksana amenorea primer terkait sindroma turner. Studi kasus ini menggunakan metode pendekatan prospektif sehingga dapat mencapai diagnosis terbaik. Didapatkan hasil seorang perempuan, usia 22 tahun, belum pernah mengalami haid sampai usia 21 tahun. Pasien pertama kali haid dengan durasi 6 hari setelah mengkonsumsi obat yang mengandung kombinasi Estradiol valerat dan Norgestrel pada bulan November 2019. Setelah berhenti minum obat selama 3 bulan, pasien tidak mengalami menstruasi dan siklus menstruasi tidak teratur lagi. Pemeriksaan status generalisata dalam batas normal. Pemeriksaan  tanda seks sekunder didapatkan tanner stage M2P2.  Pemeriksaan ultrasonografi menunjukkan uterus berukuran kecil dengan ovarium kiri sulit dinilai dengan kesan hipoplasia uterus. Pemeriksaan laboratorium didapatkan kadar hormon tiroid FT4: 18,59 ng/dL, TSHs: 5,9 ng/dL, Anti mullerian hormon (AMH): <0,01 ng/mL, FSH: 102,11 mIU/mL, dan estradiol: <9 pg/dL. Hasil pemeriksaan kromosom didapatkan kariotipe 45X dengan kehilangan satu kromosom seks X.  Pasien dengan sindroma Turner klasik yang mengalami kelainan kromosom seks 45X hipoplasia uterus dengan hipergonadotropik dan hipogonadisme serta hipotiroidisme, dibutuhkan tatalakasana yang tepat dengan pendekatan menyeluruh dan pendekatan psikososial [PS1] [PS2]
KEANEKARAGAMAN JENIS TUMBUHAN HERBA di KAWASAN PEGUNUNGAN DEUDAP PULO ACEH KABUPATEN ACEH BESAR Hilwah Nora; Raudhatul Jannah; Yuni Sukma; Mulyadi Mulyadi; Muslich Hidayat
Prosiding Seminar Nasional Biotik Vol 6, No 1 (2018): PROSIDING SEMINAR NASIONAL BIOTIK VI 2018
Publisher : Prosiding Seminar Nasional Biotik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.281 KB) | DOI: 10.3126/pbio.v6i1.4292

Abstract

Kawasan pegunungan Deudap merupakan suatu kawasan konservasi yang berada di Pulo Aceh kabupaten Aceh Besar. Di kawasan tersebut terdapar berbagai macam tumbuhan diantaranya tumbuhan herba sebagai komponen vegetasi tumbuhan bawah, semak, tiang dan pohon. Tumbuhan herba adalah tumbuhan (pendek, kecil) yang mempunyai batang basah karena mengandung banyak air dan batangnya tidak berkayu. Penelitian ini dilaksanakan pada tanggal 13  sampai 16 April 2017 di Aceh Besar. Tujuan penelitian ini adalah untuk mengetahui keanekaragaman jenis tumbuhan herba yang terdapat d kawasan tersebut. Metode yang digunakan adalah Metode Kuadrat, dengan pengambilan sampel diletakkan  plot sampling dengan ukuran (1x1meter) untuk jenis herba. Hasil penelitian menunjukkan bahwa: terdapar 17 jenis dengan jumlah 259 spesiesi tumbuhan herba, spesies tumbuhan herba yang dominan adalah Rumput teki (Cyperus rotundus). Keanekaragaman jenis tumbuhan herba di kawasan hutan Deudap adalah tergolong rendah, yang ditunjukkan oleh indeks keanekaragaman H’ = 0,98314.
STUDI PENGARUH ELEMENT SIZE PADA ANALISIS ELEMEN HINGGA TERHADAP DISTRIBUSI TEGANGAN PADA KASUS FRAKTUR TULANG TIBIA Afif Hiranda; Hilwah Nora; Syarizal Fonna; Syifaul Huzni
Prosiding Seminar Nasional USM Vol 2, No 1 (2019): Semnas Multidisiplin Ilmu
Publisher : Universitas Serambi Mekkah

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Abstract

Tibia is the second largest bone which is a leg strengthening bone, which connects the knee with the ankle. In carrying out its duties, the tibia receives a great load to hold the weight of the human body. In certain cases, the tibia is susceptible to failure due to activities carried out by humans. Therefore, it is necessary to estimate the effect of the load on the strength of tibia. The purpose of this study is to analyze the distribution of stress on tibia, under stand-position. The model of tibia is analyzed using ANSYS software, which is based on the finite element method. The load given to the tibia model is 400 N on the lateral condyle section, with the assumption that the human body weight is 70 kg. Fixed support is given in the medial malleolus section. Three mesh sizes used in this study are coarse mesh, medium mesh, and fine mesh. From the finite element analysis result, it was shown that the Von Misses stress obtained from coarse mesh are higher compare to medium mesh and fine mesh.
Co-Authors Aditya, Rizka Afif Hiranda Al-shather, Zain Alfatah, Ridwan Andi Ulfa Tenri Pada Cut M. Yeni Cut M. Yeni Cut N. Maracilu Cut Nurmaliah Dewi Karlina Rusly Dewi, Tengku P. Dewi, Tgk. Puspa Filsa P. Anwar Fitri Dewi Ismida Ghina Salsabila Rahman Haryani, Siti D. Hasanuddin Hasanuddin Hasanuddin Hasanuddin Indirayani, Ima Kartini Hasballah Khalisa, Ighra Maharani, Cut R. Maimun Syukri Muhammad Ridwan Muhammad Ridwan Muhibbuddin Muhibbuddin Mulyadi Mulyadi Muslich Hidayat Qadri, Sofyan Rajuddin Rajuddin Raudhatul Jannah Roziana Roziana, Roziana Rusnaidi Safrida Safrida Salmah Salmah Sarah I. Nainggolan Sarjani Sarjani Syarizal Fonna Syifaul Huzni Yuni Sukma