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Herlyn-Werner-Wunderlich syndrome: Challenges in diagnosis and management Roziana, Roziana; Nora, Hilwah; Maharani, Cut R.; Yeni, Cut M.; Dewi, Tengku P.; Rusnaidi, Rusnaidi; Indirayani, Ima; Aditya, Rizka; Al-shather, Zain; Haryani, Siti D.
Narra J Vol. 3 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i2.223

Abstract

Herlyn-Werner-Wunderlich syndrome (HWWS), also known as OHVIRA syndrome (obstructed hemivagina and ipsilateral renal anomaly) is a complex congenital malformation characterized by a triad including uterine didelphys, hemivaginal obstruction, and ipsilateral renal agenesis. In this case report, we present a case of HWWS along with the challenges in diagnosis and multi-step treatment processes. A 25-year-old woman presented to Dr. Zainoel Abidin Hospital in Banda Aceh, Indonesia with a chief complaint of lower back pain for the past six months (two months after the marriage). The patient also complained of late menstruation, followed by thick yellow vaginal discharge resembling malodorous pus occurring after menstruation. Additionally, a history of fever and pain during intercourse was reported. Vaginal examination revealed purulent fluid emerging from a pinpoint hole on the right vaginal wall. Vaginal palpation revealed a two-branched uterus, along with a palpable cystic mass on the right vaginal wall. Ultrasound examination indicated the presence of the right and left hemi-uteri, measuring 4.7x1.35 cm and 5.7x1.26 cm in size, respectively with both ovaries appearing normal. Fluid accumulation was observed in the right hemivagina, while the left kidney exhibited normal features, and the right kidney showed signs of hypoplasia. The patient was diagnosed with uterus didelphys, fluid accumulation in the hemivagina, and right kidney hypoplasia. Magnetic resonance imaging (MRI) confirmed uterus didelphys and revealed narrowing of the right hemivagina, suggestive of HWWS. Hysteroscopy was performed to resect the vaginal septum with laparoscopic guidance, along with drainage of hematocolpos, pyocolpos and placement of an intracervical mold. Despite HWWs having conservative gradual management, it was opted to perform vaginal septum resection, hematocolpos and pyocolpos drainage and placement of an intracervical mould in this case, in order to relieve symptoms and restore the reproductive and sexual functions.
Bicornis unicollis uterus as a risk factor of preterm birth: A case of young woman with multiple premature births Hasanuddin, Hasanuddin; Maharani, Cut R.; Nora, Hilwah; Roziana, Roziana; Aditya, Rizka; Dewi, Tgk. Puspa; Qadri, Sofyan
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.229

Abstract

Bicornis unicollis uterus is a rare congenital uterine abnormality that occurs due to the failure of Mullerian duct fusion early in the development of the female internal genitalia system. In this case report, we present a woman with bicornis unicollis uterus who had preterm birth. A 30-year-old female patient with two caesarean sections history with premature babies was presented to the hospital with a complaint of regular contractions for twelve hours in her third preterm pregnancy. The patient has no particular symptoms besides acute abdominal pain. The ultrasonography examination indicated a uterus didelphys with breech presentation fetus. Due to the patient’s caesarean history and the fetal presentation, an emergency caesarean section was decided and performed. It was found that the gravid uterus was on the left and the baby was subsequently delivered with a complete placenta. Postoperative condition of the patient was shown to be stable while the baby underwent an intensive care at the neonatal intensive care unit. This case report highlights that early diagnosis in this rare case is critical since bicornis unicollis uterus are mostly asymptomatic. Caesarean section was chosen in the present case based on consideration of the fetal and maternal clinical conditions.
Pola Kasus Onkologi-Ginekologi di Bangsal Ginekologi RSUD Zainoel Abidin 2021-2022 Alfatah, Ridwan; Salmah, Salmah; Khalisa, Ighra; Nora, Hilwah
Jurnal Ilmu Medis Indonesia Vol. 4 No. 2 (2025): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jimi.v4i2.4351

Abstract

Purpose: This study aimed to determine the pattern of oncological and gynecological cases in the Gynecological Inpatient Room at RSUD Zainoel Abidin for the period June 2021-June 2022.. Methodology: This descriptive retrospective study obtained data from the inpatient register book by identifying age, domicile, diagnosis, action, length of treatment, and outcomes after treatment for the period June 2021-June 2022. Results: A total of 514 patients met the inclusion criteria, with 139 having oncology and the remaining gynecological issues. The largest age groups for oncology patients were 50-59 years (36.69%) and for gynecology, 40-49 years (42.40%), respectively. Most of the patients were from Aceh Besar (15.56%, 80 patients). Ovarian carcinoma was the most common oncology case (57.55%), whereas uterine myomas were the most common in gynecology (27.73%). Of these, 343 (66.73%) underwent laparotomy. The highest number of admissions occurred in January 2022 (11.48%), with an average hospital stay of 7.39 days for oncology and 6.43 days for gynecology. Of the patients, 87.94% were discharged alive and 1.17% died. Conclusion: This study found that most gynecological inpatients treated at RSUD Zainoel Abidin had leiomyoma utery (age range–40-49 and underwent laparotomy with an average length of stay of 13.35 days and good outcome. Limitations: The limitations of this study include the retrospective method, data coverage from only one hospital, and reliance on secondary records that may not always be complete or consistent. Contribution: This study can contribute to the optimization of hospital policies related to the management of oncology-gynecology patient care.
Hiploplasia Uterus dengan Amenorea Primer pada Sindroma Turner: Laporan Kasus Rajuddin Rajuddin; Sarjani Sarjani; Hilwah Nora
JURNAL IMPLEMENTA HUSADA Vol 2, No 2 (2021)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v2i2.10133

Abstract

Amenorea merupakan kondisi yang ditandai dengan ketidakadaan periode[PS1][PS2] menstruasi pada perempuan usia reproduksi. Kondisi ini terjadi akibat adanya kegagalan perkembangan alat reproduksi seperti ketidakadaan rahim, kegagalan ovarium serta anomali urogenital seperti kelainan duktus Mullerian. Diagnosis yang akurat sangat menentukan manajemen yang tepat dan optimal dalam penatalaksanaan. Laporan kasus ini bertujuan untuk menjelaskan mengenai pendekatan diagnostik serta tatalaksana amenorea primer terkait sindroma turner. Studi kasus ini menggunakan metode pendekatan prospektif sehingga dapat mencapai diagnosis terbaik. Didapatkan hasil seorang perempuan, usia 22 tahun, belum pernah mengalami haid sampai usia 21 tahun. Pasien pertama kali haid dengan durasi 6 hari setelah mengkonsumsi obat yang mengandung kombinasi Estradiol valerat dan Norgestrel pada bulan November 2019. Setelah berhenti minum obat selama 3 bulan, pasien tidak mengalami menstruasi dan siklus menstruasi tidak teratur lagi. Pemeriksaan status generalisata dalam batas normal. Pemeriksaan tanda seks sekunder didapatkan tanner stage M2P2. Pemeriksaan ultrasonografi menunjukkan uterus berukuran kecil dengan ovarium kiri sulit dinilai dengan kesan hipoplasia uterus. Pemeriksaan laboratorium didapatkan kadar hormon tiroid FT4: 18,59 ng/dL, TSHs: 5,9 ng/dL, Anti mullerian hormon (AMH): 0,01 ng/mL, FSH: 102,11 mIU/mL, dan estradiol: 9 pg/dL. Hasil pemeriksaan kromosom didapatkan kariotipe 45X dengan kehilangan satu kromosom seks X. Pasien dengan sindroma Turner klasik yang mengalami kelainan kromosom seks 45X hipoplasia uterus dengan hipergonadotropik dan hipogonadisme serta hipotiroidisme, dibutuhkan tatalakasana yang tepat dengan pendekatan menyeluruh dan pendekatan psikososial[PS1][PS2]