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All Journal Jurnal Aisyah : Jurnal Ilmu Kesehatan Science Midwifery The Journal of Indonesia Sustainable Development Planning (JISDeP) The Avicenna Medical Journal
Yona Mimanda
State Islamic University Syarif Hidayatullah Jakarta
Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Preliminary Study in Overview of CYP2A6 Gene Variation in Infertile Male Patients Jihadin Rasyadi Mumtaz; Zeti Harriyati; Chris Adhiyanto; Nurul Hiedayati; Yona Mimanda; Muniroh Muniroh
The Avicenna Medical Journal Vol 2, No 1 (2021)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (8883.422 KB) | DOI: 10.15408/avicenna.v2i1.19717

Abstract

Introduction: Infertility is a condition which is described by WHO as inability for having children after one year of relationship without birth control. this condition can be caused both from inside and outside the body. One of the major outside factors is exposure to chemical substances, which in this case nicotine substance that came from cigarettes. The CYP2A6 gene is a coding gene for the xenobiotic metabolic enzyme, in this case nicotine which can cause infertility in men. Mutations in this gene can lead to nicotine buildup, increasing nicotine effect thus increasing the risk of infertility in men. The aim of this study was to determine whether there were variations in the CYP2A6 gene in male infertile patients.Methods: The method used was the isolation of infertile and fertile sperm DNA samples (five samples each) which were then amplified at the target DNA (CYP2A6) by PCR method and then sequenced to see the nucleutide sequence.Result: The results of this study showed that there were variations in the CYP2A6 gene that occurred only in infertile patients, heterogeneous mutations in the 7788th(C-A), 8040th (C-T), 7661st (G­-C) nucleutide sequence of the CYP2A6 gene and SNP mutations in the 8250th(T>C), 8409th (T>G/C), and 8428th(C>T) nucleutide sequence of the CYP2A6 gene.Conclusion: The conclusion of this study is that there are CYP2A6 variations that found only in infertile male patients.
The Effect of Tangible on Hemodialysis Patient Satisfaction Hidayat, Dinnisa Haura Zhafira; Mimanda, Yona; Maikel, Mahesa Paranadipa
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 2 (2024): September
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i2.2433

Abstract

This study aims to find out the effect of tangible on hemodialysis patient satisfaction. The location and year of the study is at Rumah Sakit Haji Jakarta in 2022. The writer believes that there is a positive effect of tangible towards hemodialysis patient satisfaction at Rumah Sakit Haji Jakarta. Method: This study is a quantitative study with a cross-sectional design. The population in this study were every hemodialysis patients at Rumah Sakit Haji Jakarta. The sample of this research was obtained by using consecutive sampling technique with a sample of 118 hemodialysis patients in Rumah Sakit Haji Jakarta. Data collection was done using a questionnaire with 1 month as the length of time for data collection. The data analysis performed is simple linear regression analysis using SPSS 26. From the scale of 4, the description analysis shows that tangible scores an average of 3,37, meanwhile the dimension of patient satisfaction with the highest score of interpersonal behaviour with an average of 3,33 and the lowest score is financial aspect with an average of 3,09. The study shows that tangible gives positive and significant effect towards hemodialysis patient satisfaction at Rumah Sakit Haji Jakarta. The outcome of this study is expected to become a reference and guide for health care provider in increasing patient satisfaction.
Relationship between age, gender, BMI, comorbidity and AEFI Variables with S-RBD antibody levels post covid-19 vaccination Mimanda, Yona; Muniroh, Muniroh; Sari, Nurmila
Science Midwifery Vol 12 No 2 (2024): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i2.1589

Abstract

The coronavirus disease 2019 (COVID-19) pandemic is a global problem caused by the SARS CoV-2 virus. Covid-19 vaccination, which is believed to be a solution, started after almost a year of the pandemic. The vaccination program in Indonesia initially used the Sinovac vaccine, a vaccine made from killed or inactivated viruses. This platform has been used in making vaccines for a long time. Vaccination at the UIN Syarif Hidayatullah Jakarta campus uses a vaccine made by PT Bio Farma, COVID-19 Vaccine, with the same raw materials as Sinovac. Cross-sectional research and research subjects were 53 lecturers and teaching staff who had received 2 doses of the COVID-19 Vaccine. Characteristics of age, gender, body mass index, comorbidities and adverse events after immunization (AEFI) were obtained from interviews, questionnaires and physical examination. It was found that there were no significant differences in S-RBD IgG antibody levels in young and elderly adults (p=0.85), male and female groups (p=0.74), groups with comorbidities (p=0.93), history of AEFI (p=0.78). However, there was a significant difference between normal BMI and abnormal BMI (p=0.03). The variable that had a significantly different relationship in this study was the mean level of IgG S-RBD antibodies in the overweight and obese groups with normal weight.
The Impact of Responsiveness on Patient Satisfaction: Ensuring Healthy Lives and Well-Being Through Sustainable Development Goal 3 Hidayat, Dinnisa Haura Zhafira; Mimanda, Yona; Maikel, Mahesa Paranadipa
The Journal of Indonesia Sustainable Development Planning Vol 6 No 1 (2025): April
Publisher : Pusbindiklatren Bappenas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46456/jisdep.v6i1.640

Abstract

Responsiveness involves emotional support, effective communication, and respect, essential to achieving Sustainable Development Goal 3. The SDG 3 aims to ensure healthy lives and promote well-being. Therefore, aligning the principles of SDG 3 with healthcare practices will create a better healthcare environment. This study examines the effect of responsiveness on patient satisfaction at the hemodialysis unit of Rumah Sakit Haji Jakarta using a quantitative cross-sectional design with primary data collection and simple regression analysis. Findings indicate that responsiveness significantly and positively affects patient satisfaction at the hemodialysis unit of Rumah Sakit Haji Jakarta. In essence, greater attentiveness and quicker responses from healthcare providers lead to higher patient satisfaction. This outcome highlights the importance of ensuring healthcare services, especially in critical care areas like hemodialysis. These findings offer valuable insights and serve as a guiding reference for healthcare providers to improve patient care quality and achieve overall patient satisfaction.
Co-Authors CHRIS ADHIYANTO Hidayat, Dinnisa Haura Zhafira Jihadin Rasyadi Mumtaz Mahesa Paranadipa Maikel Muniroh Muniroh Muniroh, Muniroh Nurul Hiedayati Sari, Nurmila Zeti Harriyati