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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Journal of Issues in Midwifery Jurnal Aisyah : Jurnal Ilmu Kesehatan Science Midwifery Jurnal EduHealth Jurnal Multidisiplin Madani (MUDIMA) Formosa Journal of Applied Sciences (FJAS) Formosa Journal of Sustainable Research (FJSR) Jurnal Indonesia Sosial Sains International Journal of Integrative Sciences Jurnal Kesehatan Metro Sai Wawai Oshada Jurnal Penelitian Sains dan Kesehatan Avicenna Aspiration of Health Journal
Novida Ariani
Universitas Brawijaya
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Peningkatan Ekspresi Matrix Metalloproteinase-9 Ligamentum Sacrouterina dan Otot Levator Ani Postpartum Rattus Norvegicus Novida Ariani
Jurnal Kesehatan Metro Sai Wawai Vol 14, No 2 (2021): Jurnal Kesehatan Metro Sai Wawai
Publisher : Poltekkes Kemenkes Tanjung Karang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jkm.v14i2.2997

Abstract

Background: Vaginal delivery is a risk factor for pelvic organ prolapse. The biomolecular mechanism that links it is still unclear, thought to be through Matrix Metalloproteinase 9 (MMP-9). Purpose: This study aims to determine the increase in MMP-9 in the supporting tissues of the pelvic organs, especially the sacrouterine ligament and levator ani muscles in the postpartum period. Methods: This study was an observational cohort study on 5 female rats of Rattus norvegicus Wistar strain. Which were divided into nulliparous groups, postpartum day 1, day 3, and day 7. MMP-9 expression was calculated and analyzed using ANOVA. Results: There was a significant difference (p=0.01) of MMP-9 expression in the sacrouterine ligament between nulliparous rats, postpartum day 1, day 3, and day 7. There was also a significant difference (p=0.00) levator ani muscle MMP-9 expression between nulliparous rats, postpartum day 1, day 3, and day 7. There was a trend of increasing MMP-9 expression on the 1st to 3rd day postpartum, then decreasing gradually on the 7th day. Conclusion: Delivery changes the expression of MMP-9 in pelvic floor tissues such as the sacrouterine ligament and levator ani muscle and these changes are time-dependent.Abstrak. Latar Belakang: Persalinan pervaginam merupakan faktor resiko prolaps organ panggul. Mekanisme biomolekuler yang menghubungkannya masih belum jelas, diduga melalui perantaraan Matriks Metalloproteinase 9 (MMP-9). Tujuan: Penelitian ini bertujuan untuk mengetahui peningkatan MMP-9 pada jaringan penyokong organ panggul, terutama ligamentum sacrouterina dan otot levator ani periode post partum. Metode: Penelitian ini adalah studi observational cohort pada 5 tikus betina Rattus norvegicus strain Wistar. Yang terbagi menjadi kelompok nullipara, postpartum hari ke-1, hari ke-3 dan hari ke-7.. Preparat jaringan ligamentum sacrouterina dan otot levator ani diwarnai dengan imunohistokimia. Ekspresi MMP-9 dihitung dan dianalisa dengan menggunakan ANOVA. Hasil: Terdapat perbedaan yang signifikan (p=0,01) ekspresi MMP-9 pada ligamentum sacrouterina antara tikus nullipara, postpartum hari ke-1, hari ke-3, dan hari ke-7. Terdapat pula perbedaan yang signifikan (p=0,00) ekspresi MMP-9 otot levator ani antara tikus nullipara , postpartum hari ke-1, hari ke-3, dan hari ke-7.  Tampak tren peningkatan ekspresi MMP-9 pada hari ke-1 hingga ke-3 postpartum, selanjutnya menurun bertahap pada hari ke-7. Simpulan: Persalinan mengubah ekspresi MMP-9 pada jaringan dasar panggul seperti ligamentum sacrouterina dan otot levator ani dan perubahan ini bersifat time-dependently.
Pengaruh Ekstrak Calendula Officinalis Terhadap Lama Penyembuhan Luka Sayat Pada Tikus Putih (Rattus Norvegicus) Husnul Khotimah; Novida Ariani; Lubna Maimunah
Jurnal Penelitian Sains dan Kesehatan Avicenna Vol 2 No 3 (2023): Jurnal Penelitian Sains dan Kesehatan Avicenna
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat (LPPM), Institut Teknologi Dan Kesehatan (ITK) Avicenna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69677/avicenna.v2i3.57

Abstract

Latar Belakang: Konsep perawatan luka saat ini telah berkembang termasuk juga pemanfaatan jenis obat topikal yang digunakan. Tanaman herbal telah banyak digunakan dan dimanfaatkan sebagai obat topikal untuk dan penyembuhan luka sebagai pengganti antibiotik kimiawi. Bunga calendula diduga merupakan salah satu obat herbal yang dapat dimanfaatkan untuk perawatan dan penyembuhan luka. Tujuan: untuk mengetahui pengaruh pemberian ekstrak bunga calendula terhadap lama penyembuhan luka sayat pada tikus putih. Metode: penelitian merupakan penelitian eksperimental dengan rancangan Posttest-only control group design dan dianalisis menggunakan uji statistik One Way ANOVA. Jumlah sampel yang diperlukan adalah 20 ekor tikus putih yang terdiri dari kelompok vaseline (K-), kelompok povidone iodine (K+), kelompok ekstrak calendula konsentrasi 10% (PI), kelompok ekstrak calendula konsentrasi 15% (PII), dan kelompok ekstrak calendula konsentrasi 25% (PIII). Penyembuhan luka sayat diamati setiap hari sampai luka menutup. Hasil: uji One Way ANOVA didapatkan nilai p=0.077. Konsentrasi terbaik dalam terapi adalah ekstrak bunga calendula 10%, yang dapat mempersingkat waktu penyembuhan luka sayat pada tikus 3,5 hari lebih cepat dibandingkan kelompok kontrol. Kesimpulan: ekstak calendula officinalis berpengaruh terhadap lama penyembuhan luka sayat pada tikus putih (rattus novergicus
Latest Innovations in Midwifery Practice to Raise Family Planning and Reproductive Health Awareness Meyana Marbun; Nikmatul Khasanah; Irwandi Irwandi; Novida Ariani; Ida Widiawati
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (625.238 KB) | DOI: 10.30604/jika.v8i2.2024

Abstract

Awareness of family planning and reproductive health is essential to Indonesian society. This is because the maternal and infant mortality rates are still relatively high, especially in rural areas. This research then aims to look at innovations that can be carried out in midwifery practice to help increase awareness of family planning and reproductive health. This research will be carried out using a descriptive qualitative approach. This research method is a literature study. This research found that family-focused health education can help reduce unwanted pregnancy, domestic violence, and maternal and child mortality rates. In addition, the presence of psychological support can also help couples deal with stress and anxiety during pregnancy and childbirth. This psychological support can ultimately help the family mentally and physically. Finally, a collaboration that occurs between governments can help people who live in areas that are marginalized or difficult to reach. Through the implementation of these innovations, it is hoped that awareness of family planning and reproductive health can increase.
Perbedaan Tingkat Pengetahuan tentang Resiko Kehamilan Usia Dini terhadap Kejadian Kehamilan Usia Dini di Puskesmas Wagir Kabupaten Malang Ariani, Novida; Agustin, Danik; Irmawati, Oktin
Aspiration of Health Journal Vol. 2 No. 2: Aspiration of Health Journal, Juni 2024
Publisher : LPPM Institut Teknologi Dan Kesehatan Aspirasi

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Abstract

Early pregnancy is a pregnancy where the mother's age is less than 20 years, it is closely related to the high risk of pregnancy. One of the factors causing the increasing incidence of early pregnancy is the lack of knowledge about the dangers of early pregnancy among adolescents. A low level of knowledge about pregnancy can influence adolescents in behaving negatively so that it can cause pregnancy in adolescents. This study is to determine the different levels of knowledge about the risk of early pregnancy on the incidence of early pregnancy in the Wagir Health Center of Malang Regency. The research design used in this study is quantitative with a case control approach. This study included 60 respondents using the purposive sampling method. The results of the study showed that the level of knowledge in pregnant women aged >20 years was better than the level of knowledge of pregnant women aged <20 years. The results of the Chi-Square test obtained p = 0.000 < 0.05 which showed that H0 was rejected. This means that there is a significant difference in the level of knowledge between pregnant women aged >20 years and pregnant women aged <20 years at the Wagir Health Center in Malang Regency.
Relationship Between The Level Of Knowledge About Sexually Transmitted Disease (STDs) And Personal Hygiene Behavior Of External Genitalia Organs In Female Teenagers Ariani, Novida; Asmika, Asmika; Hanesty, Avila
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Background: Sexually Transmitted Disease (STDs) are a health problem that is still quite critical and receives attention until now. This disease often affected by teenagers aged 15-24 years, especially female teenagers. One of the factors causing the emergence of sexually transmitted disease in female teenagers is the vulnerability of external genitalia organs to infection. If this is followed by poor personal hygiene behavior and is not treated immediately, it can cause infertility. Purpose: To find out the relationship between the level of knowledge about sexually transmitted disease and personal hygiene behavior of external reproductive organs in female teenagers at SMA Brawijaya Smart School Malang. Methodes: The research design used analytical observational by cross sectional approach. A total of 84 female students were sampled according to the inclusion and exclusion criteria. Data was obtained through instruments research in the form of questionnaires filled in by respondents. Then, data is presented in the form of frequency distribution table and processed using chi-square test method. Result: The results showed that there was a significant relationship between the level of knowledge about sexually transmitted disease and personal hygiene behavior of external genitalia organs in female teenagers. Conclusion: Based on results of research, there was a relationship between the level of knowledge about sexually transmitted disease and personal hygiene behavior of external genitalia organs in female teenagers at SMA Brawijaya Smart School Malang. Female Teenagers are advised to maintain reproductive health with increase the knowledge from trusted sources so that understanding does not become wrong.
Acupressure in the Management of Hyperemesis Gravidarum: A Systematic Analysis Ariani, Novida
Jurnal EduHealth Vol. 15 No. 04 (2024): Jurnal EduHealt (inpres), Year 2024
Publisher : Sean Institute

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Abstract

Pregnant women who experience more severe emesis gravidarum (nausea and vomiting) are known as hyperemesis gravidarum, this can affect the health of the mother and baby if not treated. To analyze and compile the latest scientific evidence to evaluate the benefits and techniques of acupressure as a method of managing emesis gravidarum, so that it does not develop into hyperemesis gravidarum. This research method is a systematic review with a systematic review based on PRISMA. Literature search based on research articles published in the last 10 years. Literature was obtained from a database of medium to high quality criteria using relevant keywords, namely "acupressure", "hyperemesis gravidarum", "nausea", "vomiting", "clinical study", "experimental study", then selected according to the inclusion and exclusion criteria of the study, appropriate research articles were continued in the PICOT table. Results: Ten studies that passed the inclusion criteria compared 5 different therapies where the most therapy used P6 acupressure and overall were considered to have a low risk of bias. The findings showed that acupressure can reduce the intensity of nausea and vomiting, reduce serum IL-6 levels, lower PUQE scores, better urine ketone results, reduce the frequency of antiemetic administration, and reduce the length of treatment. TherapyAcupressure has the potential to reduce symptoms of nausea and vomiting in pregnancy, especially to prevent the severity towards the diagnosis of Hyperemesis Gravidarum. However, further research with a validated scoring system, diagnostic criteria, clear outcome measures, and conducting larger studies is needed to confirm its effectiveness.
The Potential of Young Dates (Phoenix dactylifera) as an Agent in Supporting the Oogenesis Process: A Systematic Analysis Novida Ariani
International Journal of Integrative Sciences Vol. 3 No. 12 (2024): December 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijis.v3i12.12926

Abstract

This study examines the potential of young dates (Phoenix dactylifera) as a nutritional agent in supporting the oogenesis process, which is an important aspect of women's reproductive health. The introduction identifies that infertility is a global health problem affecting 10-15% of couples in Indonesia, and there is an urgent need for an alternative approach to infertility treatment. Young dates, which are known to be rich in bioactive compounds such as antioxidants and essential nutrients, have the potential to improve egg quality and support reproductive health. The method used in this study uses a systematic literature review approach by analyzing 557 articles from various databases. Selection was carried out based on strict inclusion and exclusion criteria, resulting in 9 relevant articles for further analysis. This process follows PRISMA and JBI guidelines to ensure the validity and reliability of the data. The results showed that young dates had a positive effect on hormonal balance, increased levels of FSH and LH hormones, and improved ovarian structure in animal models. Research has also found that young dates function as antioxidants that can protect reproductive cells from oxidative damage, as well as increase the number of ovarian follicles. The discussion in this study emphasizes the importance of young dates in improving the oogenesis process and overall female reproductive health. The study concluded that young dates may be a promising herbal therapy for improving female fertility, with recommendations for further research to understand the specific mechanisms underlying the effects. The results of this study are expected to contribute to the development of alternative treatment strategies for infertility problems in the future.
Yoga Therapy for Pregnant Women to Overcome Stress in Premature Labor Ariani, Novida
Oshada Vol. 2 No. 3 (2025): Oshada Journal - June
Publisher : PT. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/2kyaev89

Abstract

Globally, prematurity is one of the leading causes of death in children under the age of 5. Premature childbirth is a problem in the world, including Indonesia. The occurrence of preterm labor in general is due to the influence of stress that results in HPA activation in the mother and fetus. The provision of complementary therapy to pregnant women is one of the alternatives that health workers can provide to pregnant women to prevent premature labor. This article wants to raise how the effect of giving yoga therapy to pregnant women to overcome stress in premature labor. Data were collected using electronic databases through Google Schoolar, Pubmed and Science Direct related to the original article that researched the provision of yoga therapy to overcome stress in premature labor that met the inclusion and exclusion requirements. Based on the total library, 600 were identified and as many as 100 additional articles were identified. A total of 630 studies failed to meet the inclusion criteria and 70 articles were read in their entirety, so that as many as 11 publications were used as references. There is an effect between the administration of yoga on the incidence of premature labor.
Co-Authors Adhinda Resta Camelia Anjar Diasti Amna Asmika Asmika Catur Wilujeng Danik Agustin, Danik Hanesty, Avila Hikmawan Wahyu Sulistomo HUSNUL KHOTIMAH Ida Widiawati, Ida Intan Zahiroh Irmawati, Oktin Irwandi Kalsumy, Umi Lubna Maimunah Meyana Marbun Mustika Dewi Nikmatul Khasanah Ningrum Paramita Sari Nurdiana Zaenal Permata, Dear Ayu Putri Hainun Sasabela Rismaina Putri Sonia Lahita Septianingrum Syahana Aini Tatit Nurseta Yolanda Eldamayanti