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Evaluasi Terhadap Pola Pengobatan Pada Pasien Covid-19 Rawat Inap Pengguna Antivirus Berdasarkan Tata Laksananya Kurnianta, Putu Dian Marani; Nugraha, I Made Harry Prawira; Massode, Orpa; Fangidae, Powen Ester Jacqlien
Acta Holistica Pharmaciana Vol 4 No 2 (2022): Acta Holistica Pharmaciana
Publisher : School of Pharmacy Mahaganesha (Sekolah Tinggi Farmasi Mahaganesha)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62857/ahp.v4i2.101

Abstract

Coronavirus disease 2019 (COVID-19) merupakan penyakit infeksi saluran pernafasan yang disebabkan oleh severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Berdasarkan tatalaksana COVID-19 terapi farmakologi COVID-19 terdiri dari antivirus, terapi suportif (vitamin dan mineral), dan terapi simtomatis. Tujuan penelitian ini adalah untuk mengevaluasi kesesuaian terapi farmakologi pada pasien COVID-19 rawat inap yang memperoleh antivirus berdasarkan tata laksana yang disarankan oleh pemerintah. Jenis penelitian ini adalah observasional deskriptif dengan pendekatan cross-sectional. Pengambilan data menggunakan metode retrospektif berdasarkan data rekam medik pasien rawat inap terkonfirmasi COVID-19 periode September 2020 hingga Mei 2022. Penelitian ini dilakukan di salah satu rumah sakit di Denpasar yang melayani rawat inap pasien COVID-19 selama bulan Oktober 2021 hingga Agustus 2022. Kriteria inklusi dalam penelitian ini terdiri dari pasien rawat inap terkonfirmasi COVID-19 yang mendapatkan antivirus, memiliki data rekam medik yang meliputi data karakteristik serta data klinis pasien seperti profil pengobatan dan gejala. Kriteria eksklusi pada penelitian ini meliputi pasien yang tidak menyelesaikan rawat inapnya. Pada sejumlah total 152 pasien, pola pengobatan COVID-19 telah sesuai (100%) dengan pedoman tatalaksana terapi COVID-19 berdasarkan jenis obat dan indikasi gejala yang meliputi antivirus (favipiravir), vitamin (C dan D), terapi simtomatis (parasetamol), dan antibiotik (azitromisin).
Controlling Antihypertensive and Antidiabetic Agents Planning with the ABC Critical Index Method: A Case Study in Denpasar City Hospitals Yuliawati, Agustina Nila; Putri, Kadek Mita Wulandari; Wikayanti, Ni Putu Ayu Putri; Kurnianta, Putu Dian Marani
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.12573

Abstract

Non-communicable diseases such as hypertension (HT) and diabetes mellitus (DM) are the main causes of morbidity and mortality in Indonesia, including Denpasar City. Both diseases require long-term therapy with adequate drug availability to achieve successful treatment. Therefore, effective and efficient management of pharmaceutical preparation planning is very important in hospitals. This study aims to analyze the control of pharmaceutical preparation planning for hypertension and DM therapy using the ABC Critical Index method in hospitals throughout Denpasar City. This research is a descriptive observational study with a case study design conducted at four selected hospitals in Denpasar through a cluster random sampling technique. Data collected includes usage value, investment, selling price, and critical value of antihypertensive and antidiabetic drugs during 2024. The data were then analyzed using the Pareto ABC method and the Critical Index using Microsoft Excel and presented descriptively. The results show that antihypertensive and antidiabetic drugs are generally in the Pareto group C based on use value and investment, with the majority of critical value categories being in category E (>70%). ABC Critical index analysis shows that most drugs are in the Cci group, but planning priorities are in the Aci group, which includes drugs in the ARB, CCB, loop diuretics, insulin, and metformin classes. These findings provide a basis for improving drug procurement management and more appropriate budget allocation in hospitals and suggest that ongoing monitoring can minimize drug shortages that disrupt health services.
Evaluation of Antiretroviral and Tuberculosis Therapy Based on Clinical Outcomes in Patients With HIV/AIDS and Tuberculosis Co-Infection at Regional General Hospital in Denpasar Kurnianta, Putu Dian Marani; Suwirtawati, Ni Putu Dewanty; Dhrik, Mahadri
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.12652

Abstract

Human immunodeficiency virus and tuberculosis (HIV-TB) co-infection presents a significant challenge in Denpasar due to high incidence and complex treatment. This retrospective single-cohort study aimed to analyze the relationship between the results of therapy evaluation and the clinical outcomes in patients with HIV-TB. Secondary data from 20 HIV-TB treatment at a Regional General Hospital in Denpasar during 2022-2024 were evaluated. Fisher’s Exact test was performed to analyze the association between adherence to antiretroviral therapy (ART) and antituberculosis therapy (ATT), as per the guidelines, and their treatment success. Results showed predominance in males of productive age (60%), with cough as the most common symptom (75%), and 80% patients at HIV stage 4. All patients (N=20) received first-line ART and ATT. However, only 20% completed the treatment algorithm and 40% achieved treatment success. Although no significant association was found between treatment evaluation and success (p = 0.101), the relevant findings in this study emphasized the important role of rational drug use based on guidelines.  Further studies with larger samples and a prospective approach are needed to explore additional factors affecting clinical outcomes of patients with HIV-TB undergoing therapy according to the established guidelines.