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All Journal Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat MEDIA INFORMASI JFIOnline Jurnal Kesehatan
Asep Abdul Rahman
Departemen Farmasi FMIPA-ITB
Arts Humanities Dentistry Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Ekstrak Daun Binahong Mencegah Kenaikan Kolesterol Darah pada Tikus yang Diberi Pakan Lemak Tinggi Rahman, Asep Abdul; Kurniati, Neng Fisheri; Sukandar, Elin Yulinah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 8, No 2 (2016)
Publisher : Indonesian Research Gateway

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Abstract

Binahong (Anredera cordifolia (Ten.) v. Steenis) leaves empirically have been used to lower cholesterol levels. In this study, preventive activity of ethanol extracts will be tested on the animals fed with a high-cholesterol chow. Hypercholesterolemic animal model established by orally administering high-cholesterol chow, pure cholesterol, cholic acid, and propiltiourasil. The test animals were divided into 5 groups, including the positive control group, ethanol extract of binahong leaves at doses of 50 mg/kg bw, 100 mg/kg bw, and 200 mg/kg bw; and simvastatin at dose of 36 mg/kg bw. Extract was given at the same time as hypercholesterol induction. Lipid profiles were measured at the time before the induction, 15 days and 29 days after induction. Index of atherogenic was also calculated. The results showed that level of cholesterol and LDL of extract binahong at dose of 50 mg/kg (109.17±26.60 mg/dL and 55.78±23.92 mg/dL, respectively) had significant difference compared to a positive control group (p < 0.05). Furthermore, binahong extract at dose of 50 mg/kg bb had the lowest atherogenic index (0,68±0,27) and aorta thickening (150.60±41.72 μm) compared to other extracts at day 15 of induction. In conclusion, extract binahong at dose of 50 mg/kg bw rat gives the best effect to prevent the increase of cholesterol and LDL level on wistar male rats fed with a high-cholesterol chow.
Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Alpukat (Persea americana Mill) Terhadap Bakteri Staphylococcus aureus Wulandari, Gelisa; Rahman, Asep Abdul; Rubiyanti, Rani
Media Informasi Vol 15, No 1 (2019): Media Informasi
Publisher : Poltekkes Kemenkes Tasikmalaya

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Abstract

Alpukat (Persea americana Mill) adalah salah satu tanaman obat yang dikenal berkhasiat sebagai antibakteri karena kandungan senyawa antibakteri seperti saponin, alkaloid, dan flavonoid pada buah, biji dan daunnya. Namun, kegunaan kulit alpukat sebagai antibakteri pada Staphylococcus aureus belum diketahui secara pasti. Bakteri Staphylococcus aureus merupakan salah satu bakteri penyebab infeksi terbanyak di dunia. Oleh sebab itu, tujuan penelitian ini dilakukan untuk mengetahui aktivitas antibakteri ekstrak etanol kulit buah alpukat terhadap bakteri Staphylococcus aureus ATCC 25923. Ekstrak kulit buah alpukat diperoleh dengan cara ekstraksi menggunakan metode maserasi yang dilakukan selama tiga kali 24 jam dalam maserator dengan 3 kali pergantian pelarut. Kemudian dilakukan pengujian aktivitas antibakteri ekstrak etanol kulit buah alpukat terhadap Staphylococcus aureus ATCC 25923 dengan menggunakan variasi konsentrasi yaitu 20%, 40%, 60%, 80%, serta kontrol positif menggunakan kloramfenikol 5 µg/µL dan kontrol negatif menggunakan etanol 70%. Pengujian ini dilakukan dengan metode difusi kertas cakram. Hasil penelitian menunjukkan bahwa ekstrak etanol kulit buah alpukat dengan nilai rendemen 17,04% memiliki aktivitas antibakteri terhadap bakteri Staphylococcus aureus ATCC 25923. Konsentrasi 20% memiliki rata-rata diameter daya hambat (5,26 ± 0,63) mm, konsentrasi 40% (6,1 ± 0,48) mm, konsentrasi 60% (6,68 ± 0,29) mm, dan konsentrasi 80% (8,05 ± 0,23) mm.
Ekstrak Daun Binahong Mencegah Kenaikan Kolesterol Darah pada Tikus yang Diberi Pakan Lemak Tinggi Rahman, Asep Abdul; Kurniati, Neng Fisheri; Sukandar, Elin Yulinah
Jurnal Farmasi Indonesia Vol 8, No 2 (2016)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (698.021 KB) | DOI: 10.35617/jfi.v8i2.516

Abstract

Binahong (Anredera cordifolia (Ten.) v. Steenis) leaves empirically have been used to lower cholesterol levels. In this study, preventive activity of ethanol extracts will be tested on the animals fed with a high-cholesterol chow. Hypercholesterolemic animal model established by orally administering high-cholesterol chow, pure cholesterol, cholic acid, and propiltiourasil. The test animals were divided into 5 groups, including the positive control group, ethanol extract of binahong leaves at doses of 50 mg/kg bw, 100 mg/kg bw, and 200 mg/kg bw; and simvastatin at dose of 36 mg/kg bw. Extract was given at the same time as hypercholesterol induction. Lipid profiles were measured at the time before the induction, 15 days and 29 days after induction. Index of atherogenic was also calculated. The results showed that level of cholesterol and LDL of extract binahong at dose of 50 mg/kg (109.17±26.60 mg/dL and 55.78±23.92 mg/dL, respectively) had significant difference compared to a positive control group (p < 0.05). Furthermore, binahong extract at dose of 50 mg/kg bb had the lowest atherogenic index (0,68±0,27) and aorta thickening (150.60±41.72 μm) compared to other extracts at day 15 of induction. In conclusion, extract binahong at dose of 50 mg/kg bw rat gives the best effect to prevent the increase of cholesterol and LDL level on wistar male rats fed with a high-cholesterol chow.
UPAYA PENINGKATAN KEMANDIRIAN EKONOMI KELUARGA MELALUI PEMBUATAN SYRUP KUNYIT ASAM SERTA PERIJINAN USAHANYA Rahman, Asep Abdul; Aji, Nur; Herdiana, Irvan
Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Vol 3, No 3 (2019)
Publisher : Universitas Ahmad Dahlan, Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (633.658 KB) | DOI: 10.12928/jp.v3i3.1202

Abstract

Memasuki era globalisasi, kesenjangan taraf kesejahteraan merupakan hal yang utama harus dicegah, karena kesempatan yang muncul dari ekonomi terbuka hanya dapat dimanfaatkan oleh wilayah, sektor atau golongan yang lebih maju. Berdasarkan permasalahan yang ada pada tahun sebelumnya, maka pada tahun 2019 akan dibuat minuman siap saji berupa sirup kunyit asam. Hal ini untuk menjawab permasalahan dari pengabmas yang dilakukan pada tahun 2017. Metode yang digunakan yaitu dengan melakukan pendampingan kepada masyarakat melalui transfer ilmu melalui penyuluhan serta demonstrasi. Khalayak sasaran dari Program Pengabdian Masyarakat adalah Masyarakat Kelurahan Kahuripan, yang merupakan masyarakat tidak produktif secara ekonomis. Pada hakekatnya, kegiatan ini solusi terhadap permasalahan yang dihadapi mitra melalui pendekatan secara terpadu, agar dapat meningkatkan taraf perekenomian masyarakat. Dari hasil kegiatan inidi Kelurahan Kahuripan Kecamatan Tawang, Kota Tasikmalaya periode tahun 2019 telah berhasil dilaksanakan dengan luaran: tingkat pengetahuan mayarakat bertambah dalam hal pembuatan produk kunyit asam, tata cara permohonan ijin Pangan Industri Rumah Tangga dan Izin Usaha Mikro Kecil. Selain itu masyarakat dapat membuat produk sirup kunyit asam yang dapat diterima oleh konsumen.
Peran Pos Kesehatan Pesantren pada Pencegahan Kejadian Scabies di Pondok Pesantren (Studi Kualitatif) Nurlita, Diah; Rahman, Asep Abdul
Jurnal Kesehatan Vol 13 No 1 (2022): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v13i1.772

Abstract

Scabies is one of the infectious diseases that have not lost its prevalence in Indonesia. The prevalence of scabies in Indonesia in 2008 was 5.6% -12.95%. Scabies ranks third of the 12 most common skin diseases. Scabies is a common disease in boarding schools which is the result of dense occupancy, poor sanitation, and poor personal hygiene of students. Preventive Efforts are perceived as the most effective effort to Prevent scabies disease since disease Scabies treatment still leaves side effects and drug resistance. The purpose of this research is to know the description of the role of Poskestren in the prevention of disease scabies in Tasikmalaya City. The design of this research is descriptive and qualitative. The population of this research is the whole boarding school in Tasikmalaya City Health Post that has Pesantren. This research was conducted at Ruwada Medika Clinic roommates owned by Pesantren Riyadlul 'Ulum Wadda'wah Lean Cibeureum district. Promotion Efforts conducted by Poskestren for the prevention of scabies disease are in the form of counseling about PHBs at a predetermined time, providing additional nutrients and vitamins to maintain health Santri. As for preventive Efforts for the prevention of Scabies is to move the organization in the boarding school students to invite and implement the rules in the cottage, especially in terms of the maintenance of the cleanliness student room.
Co-Authors Aji, Nur Asep Gana Suganda Asep Kuswandi Elin Yulinah Sukandar Irvan Herdiana Neng Fisheri Kurniati Nurlita, Diah Rani Rubiyanti, Rani Wulandari, Gelisa Yulia, Nunung