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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Interest : Jurnal Ilmu Kesehatan Indonesian Journal of Pharmaceutical Science and Technology Journal of Pharmacopolium Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Majalah Farmasetika Journal of Experimental and Clinical Pharmacy (JECP) Edukasi Masyarakat Sehat Sejahtera (EMaSS) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Nusantara
Aji, Nur
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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UPAYA PENINGKATAN KEMANDIRIAN EKONOMI KELUARGA MELALUI PEMBUATAN SYRUP KUNYIT ASAM SERTA PERIJINAN USAHANYA Rahman, Asep Abdul; Aji, Nur; Herdiana, Irvan
Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Vol 3, No 3 (2019)
Publisher : Universitas Ahmad Dahlan, Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (633.658 KB) | DOI: 10.12928/jp.v3i3.1202

Abstract

Memasuki era globalisasi, kesenjangan taraf kesejahteraan merupakan hal yang utama harus dicegah, karena kesempatan yang muncul dari ekonomi terbuka hanya dapat dimanfaatkan oleh wilayah, sektor atau golongan yang lebih maju. Berdasarkan permasalahan yang ada pada tahun sebelumnya, maka pada tahun 2019 akan dibuat minuman siap saji berupa sirup kunyit asam. Hal ini untuk menjawab permasalahan dari pengabmas yang dilakukan pada tahun 2017. Metode yang digunakan yaitu dengan melakukan pendampingan kepada masyarakat melalui transfer ilmu melalui penyuluhan serta demonstrasi. Khalayak sasaran dari Program Pengabdian Masyarakat adalah Masyarakat Kelurahan Kahuripan, yang merupakan masyarakat tidak produktif secara ekonomis. Pada hakekatnya, kegiatan ini solusi terhadap permasalahan yang dihadapi mitra melalui pendekatan secara terpadu, agar dapat meningkatkan taraf perekenomian masyarakat. Dari hasil kegiatan inidi Kelurahan Kahuripan Kecamatan Tawang, Kota Tasikmalaya periode tahun 2019 telah berhasil dilaksanakan dengan luaran: tingkat pengetahuan mayarakat bertambah dalam hal pembuatan produk kunyit asam, tata cara permohonan ijin Pangan Industri Rumah Tangga dan Izin Usaha Mikro Kecil. Selain itu masyarakat dapat membuat produk sirup kunyit asam yang dapat diterima oleh konsumen.
PEMANFAATAN LIMBAH KULIT BUAH RAMBUTAN SEBAGAI GEL TABIR SURYA DAN ANTI BAKTERI TERHADAP Sthaphylococcus aureus Aji, Nur; Anwari, Muhammad Taufiq; Azzahrah, Nissa Ramdian; Azizah, Zahra Nur
Journal of Pharmacopolium Vol 3, No 2 (2020)
Publisher : P3M STIKes Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jop.v3i2.628

Abstract

Formulasi Chewy Gummy “T-Sepis” (Temulawak, Serai, dan Jeruk Nipis) sebagai Upaya Peningkatan Kesehatan Masyarakat di Masa Pandemi Covid-19 Vania Armilda, Levina Hadi; Syamsiyah, Cici Nurul; Aji, Nur
Journal of Experimental and Clinical Pharmacy (JECP) Vol 3, No 2 (2023): August 2023
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v3i2.669

Abstract

Seluruh dunia terkena dampak puncak gelombang COVID-19. Kekebalan dapat ditingkatkan dengan senyawa yang disebut imunomodulator. Potensi temulawak, serai, dan jeruk nipis yang berkhasiat sebagai imunomodulator diformulasikan dalam bentuk sediaan chewy gummy. Metode yang digunakan yaitu eksperimental. Kombinasi zat berkhasiat menggunakan metode axial. Dilakukan uji organoleptik. Optimasi basis yang paling baik adalah formula 3 yaitu gelatin 40%, sukrosa 20%, dan akuadest 40%. Optimasi zat berkhasiat yang paling baik yaitu formula 4, konsentrasi paling tinggi terletak pada serai, sedangkan temulawak dan jeruk nipis mempunyai konsentrasi yang sama. Kesimpulan dari penelitian ini yaitu chewy gummy T-Sepis berpotensi sebagai imunostimulan.The whole world is being impacted by the peak of the COVID-19 wave. Immunity can be boosted by compounds called immunomodulators. The potency of temulawak, lemongrass, and lime, which are efficacious as immunomodulators, is formulated in the form of chewy gummy preparations. The method used is experimental. The combination of efficacious substances using the axial method. Organoleptic tests were carried out. The best base optimization is formula 3, namely 40% gelatin, 20% sucrose, and 40% aquadest. The best optimization of nutritious substances is formula 4. The highest concentration is found in lemongrass, while temulawak and lime have the same concentration. The conclusion of this study is that chewy gummy T-Sepis has the potential to be an immunostimulant.
PENINGKATAN PENGETAHUAN WARGA KECAMATAN MANONJAYA TENTANG TANAMAN OBAT YANG DAPAT DIMANFAATKAN SEBAGAI ANTI INFLAMASI Sutiswa, Shandra Isasi; Aji, Nur; Handayani, Nuri
Edukasi Masyarakat Sehat Sejahtera (EMaSS) : Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 1 (2024): Januari
Publisher : Poltekkes Kemenkes Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37160/emass.v6i1.307

Abstract

Inflammation is the body's defense reaction against various kinds of stimuli. The visible signs of inflammation are redness, heat, swelling, pain, and loss of function. Anti-inflammatory drugs are generally the NSIAD group which causes side effects of stomach ulcers, nausea and vomiting. Currently, people tend to choose traditional medicine using medicinal plants that are rich in benefits. There are several medicinal plants that can be used as anti-inflammatories that are not widely known by the public. Manonjaya District has plantation land and yards that can be used to grow medicinal plants. Manonjaya District has a large millennial population who do a lot of physical activity which can trigger inflammation. The Tasikmalaya Ministry of Health Polytechnic, which is part of the City of Tasikmalaya, through its role in the Tri Dharma of Higher Education, especially in the community service program, aims to improve the health status of the community. The methods used in this activity were counseling about medicinal plants that can be used as anti-inflammatory agents and distributing pocket books on anti-inflammatory medicinal plants to 20 youth organizations. Evaluation of the results of activities to increase knowledge is carried out through pre-tests and post-tests. The pre-test and post-test scores were analyzed statistically using t-Test data analysis: Paired Two Samples for Means with a significance value of 0.05. The evaluation results show that the significance value is <0.05, meaning there is an increase in participants' knowledge about medicinal plants which can be used as anti-inflammatory agents.
Gambaran Pengetahuan Dan Sikap Siswa SMA Ibnu Siena Tasikmalaya Terhadap Pencegahan Penyakit Demam Berdarah Dengue Sri, Tovani; Alifah Rahman, Qonita; Aji, Nur
Majalah Farmasetika Supl. 9 No. 1, Tahun 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v9i7.58768

Abstract

Demam berdarah dengue merupakan salah satu penyakit menular yang paling banyakterjadi di Indonesia, berpotensi menjadi wabah dan mengalami kenaikan epidemi setiap5-10 tahunnya. Salah satu tempat yang berpotensi menjadi tempat penyebaran DemamBerdarah Dengue adalah sekolah. Usia anak sekolah sangat rentan terserang dantertular DBD. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan dansikap siswa SMA terhadap pencegahan penyakit demam berdarah dengue. Metodepenelitian yang digunakan dalam penelitian ini adalah metode deskriptif kuantitatif.Pengambilan sampel menggunakan total sampling dengan jumlah responden sebanyak54 responden. Penelitian dilakukan pada bulan Mei 2023 dan data dikumpulkan dalambentuk kuesioner. Hasil penelitian didapatkan sebanyak 98,1% siswa mempunyaipengetahuan yang baik dan sebanyak 98,1% siswa mempunyai sikap yang positif.Siswa SMA Ibnu Siena memiliki pengetahuan yang baik mengenai pencegahanpenyakit DBD dan siswa memiliki sikap yang positif mengenai pencegahan penyakitDBD.
FORMULATION AND CHARACTERIZATION OF INSTANT POWDER COMBINATION OF MILK, YOLK AND TEMULAWAK (Curcuma xanthorriza Roxb) TO PREVENT STUNTING Sutiswa, Shandra Isasi; Aji, Nur
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1234

Abstract

Through its health transformation program, the Ministry of Health has replaced giving biscuits as additional food to toddlers and pregnant women to prevent stunting with animal protein made from local food. Milk and eggs are local food sources of animal proteins that can be processed into nutraceuticals. Another cause of stunting is lack of appetite, nausea, and vomiting in children during pregnancy. Temulawak is a traditional medicine that can improve appetite. A combination of milk, yolk, and temulawak can be formulated for nutraceutical preparation. This study aimed to develop and test the characteristics of instant powder combinations of milk, yolk, and temulawak to prevent stunted growth. The laboratory experimental method was used in this study. The formula was prepared by mixing temulawak extract granules with powder obtained from the freeze-drying process of milk and yolk. There were 3 variations of the combination concentration with a ratio of milk : yolk : temulawak, F1 (40:2:3), F2 (50:3:2), and F3 (60:4:1). The results of the research showed that all formulas had physical characteristics in the form of light yellow powder with a typical ginger aroma, particle size between 119.66–120.39µm, angle of repose between 36.40–44.46°, flow rate between 1.32–1 .34g/sec, specific gravity between 0.44-0.47g/mL, tap density between 0.62–0.68g/mL, compressibility between 13.00-13.33%, pH between 6.45–6, 48, dispersibility time between 02.14 – 02.17 minutes and water content between 3.48 – 4.93% according to SNI-01-2970-2006 instant milk powder ...
A STUDI LITERATUR PERBANDINGAN KADAR ASAM KLOROGENAT DAN AKTIVITAS ANTIOKSIDAN PADA KOPI ARABIKA ( Coffea arabica ) DAN ROBUSTA ( Coffea canephora ) DARI BERBAGAI TEMPAT TUMBUH Afriyanti, Fatmasari; Rubiyanti, Rani; Aji, Nur
SAINS INDONESIANA Vol. 1 No. 6 (2023): Vol. 1, No. 6 Edisi Desember 2023
Publisher : Gamma Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kopi merupakan salah satu komoditas perkebunan Indonesia. Ada dua jenis kopi yang banyak dibudidayakan dan memiliki harga jual yaitu kopi arabika (Coffea arabica) dan kopi robusta (Coffea canephora). Biji kopi dari kedua spesies ini memiliki banyak senyawa aktif, salah satunya yaitu asam klorogenat yang bermanfaat sebagai antioksidan.Antioksidan dapat mencegah pembentukan radikal bebas. Tujuan dari penelitian ini adalah untuk mengetahui kadar asam klorogenat dan aktivitas antioksidan pada biji kopiarabika (Coffea arabica) dan robusta (Coffea canephora). Jenis penelitian ini menggunakan metode studi literatur/literature review. Data yang digunakan diperoleh dari jurnal, artikel dan pustaka lainnya, kemudian diuraikan secara deskriptif dengan cara memaparkan dan membandingkan hasil penelitian kadar asam klorogenat dan aktivitas antioksidan biji kopi arabika dan robusta dari berbagai tempat tumbuh. Diperoleh 14 jurnal/artikel yang memenuhi kriteria inklusi dan eksklusi. Berdasarkan dari penelitian sebelumnya bahwa terdapat perbedaan asal tempat tumbuh dan jenis kopi memengaruhi kandungan kopi sehingga dapat memengaruhi kadar asam klorogenat dan aktivitas antioksidannya. Kadar asam klorogenat dan aktivitas antioksidan kopi robusta (Coffea canephora) lebih tinggi dibandingkan dengan kopi arabika (Coffea arabika). Kata kunci : asam klorogenat, antioksidan, biji kopi arabika, biji kopi robusta.
Liquid Hand Soap Formulation of Java Citronella (Cymbopogon winterianus) Oil Using Surfactant Combination as Foaming Agent Martihandini, Nooryza; Aminah, Mimin; Aji, Nur
Interest : Jurnal Ilmu Kesehatan INTEREST: Jurnal Ilmu Kesehatan Volume 13 Number 2 November 2024
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/interest.v13i2.600

Abstract

Background: Unhygienic hands can cause microorganism infection. Citronella oil contains citronellal, citronellol, and geraniol, which have antibacterial activity. Liquid hand soap removes the dirt and microorganisms; however, it commonly uses sodium lauryl sulphate (SLS) as a foaming agent that may irritate the skin. Lauryl glucoside is a non-ionic, non-irritating surfactant. This study aimed to formulate and characterise liquid hand soaps from citronella oil using a combination of SLS and lauryl glucoside as surfactants. Methods: The research was conducted using an experimental laboratory method. Three liquid hand soap formulas were developed from 15% citronella oil with different weight ratios of SLS and lauryl glucoside: F1 (1:2), F2 (1:1), and F3 (2:1). Then, all liquid hand soaps were evaluated for organoleptic properties, homogeneity, viscosity, pH, and foam height. Then the foam stability test was conducted after the formed foam was left for 5 minutes. Results: The results showed that all liquid hand soaps were homogeneously distributed, clear viscous liquids having a distinctive odour of citronella oil. The liquid hand soap preparations had a viscosity range of 549.7–565.8 cps, a pH in the range of 7.39–7.89, a foam height of 74–85 mm, and a stability foam of 63.52–68.91%. All formulas complied with SNI 2588:2017 criteria for liquid hand soap. Conclusion: This study presented that citronella oil could be formulated into liquid hand soap using a combination of SLS and lauryl glucoside. The optimal formula was F1 with a 1:2 ratio of SLS and lauryl glucoside. F1 had the most stable foam due to the higher concentration of lauryl glucoside, which enhances foam stability.
In Silico and In Vitro Antibiofilm Activity of Zingiber montanum Ethyl Acetate Fraction Against Propionibacterium acnes: Antibiofilm of Zingiber montanum Aji, Nur; Kumala, Shirly; Mumpuni, Esti; Rahmat, Deni
Journal of Tropical Life Science Vol. 15 No. 1 (2025)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/

Abstract

Propionibacterium acnes (P. acnes), a symbiotic bacterium involved in the development of acne, is recognized for its capacity to develop resistance due to its ability to generate biofilms. According to a previous investigation, the ethyl acetate fraction derived from Zingiber montanum exhibited anti-bacterial properties against P. acnes. Nevertheless, the causative role of biofilm formation in its resistance was not previously recognized. This study aims to ascertain the antibiofilm efficacy using in silico and in vivo methodologies. In this study, in silico examination utilized molecular docking to inhibit the quorum sensing mechanism by blocking the autoinducer 2 (AI-2) signal. The target protein was AI-2 binding periplasmic protein LuxP (PDB code: 4YRZ). Following that, an in vitro test was conducted using the crystal violet staining method, which was read using a microplate reader at a wavelength of 600 nm. The readings were expressed as percent inhibition and IC50. The in silico results showed that there were six compounds in the ethyl acetate fraction that have the potential to inhibit AI-2 signaling. Curcumin showed the highest inhibitory activity. Meanwhile, the in vitro results revealed that the ethyl acetate fraction of Z. montanum obtained the minimum biofilm inhibitory concentration (MBIC) of 2.5 % (w/v) and IC50 = 0.28 % (w/v). It can be concluded that the ethyl acetate fraction of Zingiber montanum could inhibit the biofilm formation of P. acnes.  
Effectiveness Test of Spray Gel Hand Sanitizer with Carbomer 940 as a Preventive Product in Emergency Conditions Sutiswa, Shandra Isasi; Aji, Nur; Yulia, Nunung
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.45186

Abstract

Hand sanitizer is known for its ability to kill germs quickly due to its alcohol content, making it more effective than washing hands with soap and water. However, excessive use of alcoholbased sanitizers can cause skin irritation and dryness. Alcohol is polar and volatile, leading to rapid skin dryness and reduced effectiveness. To address this, gelling agents like Carbomer 940 are added to spray gel formulations. Carbomer 940 offers high stability and low toxicity, thereby enhancing the gel’s antibacterial properties. This study aims to develop an innovative spray gel hand sanitizer using Carbomer 940. The research method used was a pure experiment, evaluating the % inhibition of microbial growth on agar media. Results showed that the spray gel with 0.05% Carbomer 940 had superior effectiveness, with 60.77% inhibition, compared to the control group using the WHO formula, which achieved 33.11%. Additionally, the spray gel had a pH of 6.5 ± 0.2, a viscosity of 135.10, and an average spray weight of 0.027 ± 0.000 g, demonstrating optimal physical quality. In conclusion, the spray gel hand sanitizer with 0.05% Carbomer 940 was more effective at inhibiting microbial growth than the WHO standard formula.
Co-Authors Afriyanti, Fatmasari Alifah Rahman, Qonita Aminah, Mimin Anwari, Muhammad Taufiq Asep Abdul Rahman Azizah, Zahra Nur Azzahrah, Nissa Ramdian Esti Mumpuni, Esti Irvan Herdiana Martihandini, Nooryza Nuri Handayani RAHMAT, DENI Rani Rubiyanti, Rani Shirly Kumala Sri, Tovani Sutiswa, Shandra Isasi Syamsiyah, Cici Nurul Vania Armilda, Levina Hadi Yulia, Nunung