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All Journal JURNAL FARMASIMED (JFM) Medical Sains : Jurnal Ilmiah Kefarmasian APMa Jurnal Pengabdian Masyarakat
Akrom
Universitas Ahmad Dahlan
Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Other

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SKRINING KESEHATAN JIWA, RELIGIUSITAS, DAN KUALITAS HIDUP MAHASISWA FARMASI DAN KEDOKTERAN PADA PANDEMI COVID-19: SCREENING OF MENTAL HEALTH, RELIGIUSITY, AND QUALITY OF LIFE OF PHARMACEUTICAL AND MEDICAL STUDENTS IN THE COVID-19 PANDEMIC Widea Rossi Desvita; Wiwara Awisarita; Muhammad Fikri; Akrom; Laela Hayu Nurani; Isabella Meliawati Sikumbang
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 2 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i2.342

Abstract

Kesehatan mental mahasiswa Farmasi dan Kedokteran perlu diskrining terhadap keberadaan COVID-19. Faktor internal yang perlu diperhatikan adalah aspek religiusitas dan kualitas hidup. Instrumen yang dikembangkan untuk pemeriksaan kesehatan mental adalah SRQ29 serta religiusitas dan kualitas hidup dengan EQ5D. Tujuan dari penelitian ini adalah untuk mengetahui kesehatan mental dan kualitas hidup mahasiswa Farmasi dan Kedokteran pada masa pandemi COVID-19. Penelitian ini merupakan penelitian cross sectional diskriptif dengan metode survey terhadap 44 responden yang meliputi 36 mahasiswa Fakultas Farmasi dan 8 mahasiswa Fakultas Kedokteran. Metode yang digunakan untuk skrining kesehatan jiwa adalah instrumen kuesioner yaitu SRQ-29 untuk skrining kesehatan jiwa dan religiusitas yang berisi 29 pertanyaan terkait kesehatan jiwa responden, dan skrining kualitas hidup dengan instrumen EQ5D. Hasil penelitian menunjukkan bahwa dari skrining SRQ29 mahasiswa farmasi dan FK  perguruan tinggi di Yogyakarta mengalami gejala PTSD (75%), cemas dan depresi (61,36%), gangguan psikotik (50%), penggunaan zat psikoaktif/ narkoba (2,27%). Berdasarkan hasil skrining religiusitas menunjukkan nilai yang tinggi terhadap keyakinan dan iman kepada Allah SWT (96,8%). Hasil EQ5D menunjukkan bahwa pandemi tidak berdampak besar pada aspek fisik, namun berdampak pada mental/ psikologis. Kesimpulan penelitian terkait kesehatan jiwa pada hasil skrining dengan instrumen SRQ29 menunjukkan bahwa mahasiswa farmasi dan FK  perguruan tinggi di Yogyakarta mengalami masalah psikososial.  Hal ini saat dikaitkan dengan religiusitas dan kualitas hidup menunjukkan adanya pengaruh faktor internal tersebut pada kesehatan jiwa.
REVIEW: THE ROLE OF HERBAL AS A THERAPY FOR ENDOTHELIAL DYSFUNCTION IN CARDIOVASCULAR DISEASES: NARRATIVE REVIEW Febriana Astuti; Akrom; Rafiastiana Capritasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1238

Abstract

Atherosclerosis, diabetes mellitus, hypertension, and aging are examples of cardiovascular illnesses, the pathogenesis of which is affected by endothelial dysfunction. Many patients with cardiovascular disease already use herbs or combine herbs with medications prescribed by doctors. Herbs have emerged as alternative treatments for health maintenance. Herbs are in increasing demand by patients and health professionals. An overview of the role of herbal plants, their active substances, and their mechanisms of action as therapies for endothelial dysfunction to prevent the worsening of cardiovascular disease is presented in this review. The research was carried out by reviewing published scientific papers using online sources, such as PubMed and Google Scholar. Herbs can be used as a therapy for endothelial dysfunction to prevent the worsening of cardiovascular disease through various mechanisms, including inhibition of oxidative stress through the COX-2 and NOX2 pathways, inhibition of NADPH oxidase, inhibition of ROS formation through Src/EGFR/Akt, and increasing nitric oxide (NO) production by activating eNOS. The benefits and potential of herbal plants in dysfunction therapy to prevent cardiovascular disease need to be further developed for plants that grow widely in Indonesia. Furthermore, it is necessary to develop mechanisms for other targets, such as immunomodulatory therapy, to prevent cardiovascular disease from worsening. Keywords: Herbals, Endothelial Dysfunction, Cardiovascular Disease
Antioxidant Potential of the Asteraceae Family in Counteracting Free Radicals in Cigarette Smoke: An Overview Aulia Syafadilla Azali; Muhammad Andy Rajab; Sofiani Lathifah; Akrom
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/4vbm3x10

Abstract

Cigarette smoke exposure triggers oxidative stress in the respiratory system through an increase in free radicals and a decrease in endogenous antioxidant activity, which contributes to lung damage and chronic diseases such as COPD and lung cancer. This study aims to investigate the potential of species from the Asteraceae family as a source of natural antioxidants in protecting the lungs and trachea from damage caused by exposure to free radicals in cigarette smoke. The method used is a Systematic Literature Review (SLR) with reference to the PRISMA 2020 guidelines. Literature searches were conducted systematically through the PubMed, ScienceDirect, and Google Scholar databases until June 2025. The inclusion criteria included in vivo studies using Asteraceae plant extracts in animals with induced oxidative stress in the respiratory system, as well as involving the measurement of biomarkers such as MDA, GSH, SOD, and CAT. Of the 198 articles found, 10 articles met the criteria and included species such as Tridax procumbens, Chromolaena odorata, Pulicaria petiolaris, and Baccharis retusa. The results showed that these species had significant antioxidant activity through their flavonoid, polyphenol, and triterpenoid compound content. However, most studies did not use a direct cigarette smoke exposure model. In conclusion, the Asteraceae family has great potential as a source of natural antioxidants to protect the respiratory system from oxidative stress, although further research with more relevant exposure models is needed. Toxicology and metabolomics approaches are also needed to strengthen the evidence for practical application in the treatment of lung diseases caused by cigarette smoke.
Edukasi Pola Hidup Sehat untuk Pencegahan Penyakit Ginjal di Masjid K.H. Sudja' Sleman Arini Salsabila; Akrom
APMa Jurnal Pengabdian Masyarakat Vol. 6 No. 2: Juli 2026
Publisher : STIKES Bhakti Husada Mulia Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47575/apma.v6i2.844

Abstract

Penyakit ginjal kronik (PGK) merupakan salah satu masalah kesehatan global dengan angka kejadian yang terus meningkat setiap tahunnya. Di sekitar wilayah Kabupaten Sleman, khususnya di kalangan masyarakat dewasa, pengetahuan mengenai fungsi ginjal, tanda-tanda awal gangguan ginjal, serta upaya pencegahannya masih tergolong terbatas. Kegiatan pengabdian masyarakat bertema “8 Tanda Awal Gangguan Ginjal” ini bertujuan untuk meningkatkan pengetahuan masyarakat dewasa mengenai edukasi pola hidup sehat dan pencegahan penyakit ginjal. Metode pelaksanaan menggunakan rancangan one-group pretest-posttest kepada 20 orang peserta dewasa di Masjid K.H. Sudja', Kabupaten Sleman, melalui media presentasi dan leaflet, diikuti dengan sesi diskusi dan tanya jawab. Hasil evaluasi menunjukkan adanya peningkatan skor rata-rata pengetahuan peserta secara signifikan, dari yang semula 72% menjadi 93% pada posttest. Hal ini menandakan bahwa edukasi kesehatan yang diberikan efektif dalam meningkatkan pemahaman peserta tentang pentingnya menjaga kesehatan ginjal. Sebagai upaya keberlanjutan, kegiatan ini diharapkan dapat diintegrasikan dengan program posbindu (pos pembinaan terpadu) atau kader kesehatan masjid setempat guna menekan risiko serta prevalensi penyakit ginjal kronik di Indonesia.
Co-Authors Arini Salsabila Aulia Syafadilla Azali Febriana Astuti Isabella Meliawati Sikumbang Laela Hayu Nurani Muhammad Andy Rajab Muhammad Fikri Rafiastiana Capritasari Sofiani Lathifah Widea Rossi Desvita Wiwara Awisarita