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All Journal Dental Journal (Majalah Kedokteran Gigi) Conservative Dentistry Journal
Febriastuti Cahyani
Faculty Of Dental Medicine, Universitas Airlangga,Surabaya,Indonesia
Dentistry

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Assessing the antibacterial efficacy of nano propolis concentrations on Streptococcus mutans Putra, Mohammad Gerald Athallah; Aulia, Zahra Maulida; Widjiastuti, Ira; Pribadi, Nirawati; Cahyani, Febriastuti
Conservative Dentistry Journal Vol. 14 No. 1 (2024): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v14i1.2024.22-23

Abstract

Background: Dental caries is a common disease among the Indonesian population, with a prevalence of dental caries in Indonesia reaching 88.8%. Streptococcus mutans is one of the types of bacteria found in caries lesions. Nano propolis has antibacterial properties that can help inhibit the growth of Streptococcus mutans bacteria, reducing the risk of dental caries. Objective: This study aims to determine the effective concentration of nano propolis ranging from 2.5% to 0.625%. Methods: The research evaluates various concentrations of nano propolis, and the minimum concentration that inhibits the growth of Streptococcus mutans is observed using the colony count method. Results: The growth of Streptococcus mutans at a concentration of 2.5% nano propolis was 0, at 1.8% it was 6, at 1.25% it was 11.4, and at 0.625% it was 42. The positive control group containing BHIB media and Streptococcus mutans bacteria showed an average colony growth of 161. Conclusion: Nano propolis at a concentration of 1.25% is effective in inhibiting the growth of Streptococcus mutans.
Apex resection treatment on tooth 21 and 22 with suspected radicular cyst Cahyani, Febriastuti; Saraswati, Widya; Mulyadi, Reyz Pasenda; Wahab, Sofi Arnesti; Halima, Siti Noorraida; Dzulfikri, Ahzahra Indah; Zubaidah, Nanik; Kunarti, Sri; Soetojo, Adioro
Conservative Dentistry Journal Vol. 14 No. 2 (2024): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v14i2.2024.87-89

Abstract

Background: Apex resection is the surgical removal of the apex or root end of a tooth. Endodontic failure is the most usual reason of treatment being performed. Retreatment may be the first option for teeth which have been treated conventionally and exhibit a persistent apical lesion. In particular, failures during conventional therapy could hinder results by leading infections to spread to inaccessible apical regions, necessitating surgery. Purpose: This case report aims to describe the management of radicular cyst on previously treated tooth. Case: A 51-year-old male patient came to Soewandhie General Hospital with a complaint of swelling on his hard palate from one year before. The left maxillary incisor has undergone root canal treatment about 1 year ago, but had not been permanently filled. Case Management: The treatments given were retreatment for 21 and root canal treatment for 22, then followed by cyst enucleation and apex resection on both teeth. Conclusion: Apex resection shows a satisfying result for treating previously treated tooth with persistent apical lesion.
Effectiveness of Nipah leaf extract (Nypa fruticans) against Streptococcus mutans biofilm as cavity cleanser Handriutomo, Yosef Kevin; Soesilo, Diana; Aprilia, Aprilia; Parisihni, Kristanti; Rayhan, Rafialdi; Cahyani, Febriastuti
Conservative Dentistry Journal Vol. 15 No. 1 (2025): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i1.2025.23-26

Abstract

Background: Streptococcus mutans is the primary bacterium responsible for dental caries, found in the biofilm on the tooth surface, known as dental plaque. Before restorative treatment or cavity care for carious teeth, a cavity cleanser is necessary to remove residual bacteria that could cause secondary caries or restoration failure. Nipah leaf extract contains phenol, flavonoids, saponins, and steroids, which can destroy bacteria by denaturing proteins and damaging bacterial cell membranes. Objective: To determine the antibiofilm activity of Nipah leaf extract against Streptococcus mutans biofilm. Materials and Methods: The materials used were Nypa fruticans leaf extract prepared using the maceration method at concentrations of 1%, 5%, 10%, and 15%, with chlorhexidine gluconate as the positive control and distilled water as the negative control. Bacteria cultured in BHI media were inoculated into a 96-well flat-bottomed plastic tissue culture plate and incubated for 24 hours at 37°C. Optical Density (OD) was measured using an ELISA reader. Results: KM: 0.039; K (-): 0.887; K (+): 0.085; P1: 0.727; P2: 0.463; P3: 0.347; P4: 0.169. The Mann-Whitney test results showed significant differences between K (+) and P1 (0.000), K (+) and P2 (0.000), K (+) and P3 (0.000), K (+) and P4 (0.005), P1 and P2 (0.000), P1 and P3 (0.000), and P1 and P4 (0.000). The results were significant as p < 0.05. Conclusion: Nipah leaf extract (Nypa fruticans) can inhibit the biofilm formation of Streptococcus mutans bacteria.
Epigallocatechin-3-gallate (EGCG) and tricalcium silicate (C_3 S) combination as an antibacterial agent against Enterococcus faecalis Ismiyatin, Kun; Cahyani, Febriastuti; Soetojo, Adioro; Widjiastuti, Ira; Pribadi, Nirawati; Nurkhalidah, Binar Najwa; Raftiani, Ardelia Sabrina; Pramesty, Azzahra Kinaya; Anindya, Cinitra
Conservative Dentistry Journal Vol. 15 No. 1 (2025): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v15i1.2025.46-48

Abstract

Background: Dental caries affects 57.6% of the Indonesian population, with Enterococcus faecalis found in 80% of deep caries cases. Conventional materials used in vital pulp therapy (VPT), such as calcium hydroxide, have limitations including transient antibacterial action and poor sealing capacity. This prompts the exploration of alternative materials like epigallocatechin-3-gallate (EGCG), a polyphenol from green tea with antimicrobial activity, and tricalcium silicate (C₃S), a bioactive cement known for dentin regeneration potential. Purpose: This review evaluates the synergistic antibacterial potential of EGCG and C₃S combinations against E. faecalis, and assesses their feasibility as an alternative in VPT. Review: EGCG disrupts bacterial membranes, inhibits biofilm formation, and suppresses virulence factors, but lacks remineralization capability. Conversely, C₃S promotes dentin repair and creates an alkaline antibacterial environment, though its efficacy diminishes over time. Their combination compensates for each other’s limitations: EGCG enhances antimicrobial potency while C₃S provides long-term alkalinity and regenerative support. Conclusion: The EGCG–C₃S combination exhibits synergistic antibacterial and regenerative effects, offering a promising alternative to current VPT materials.
Co-Authors Adioro Soetojo Adita, Farah Rahmi Aprilia Aprilia, Aprilia Arnesti Wahab, Sofi Arshila, Dea Aryandhita, Amanda Paramitha Putri Aulia, Zahra Maulida Cinantya, Aulia Dian Cinitra Anindya Devi Eka Juniarti Dian Agustin Wahjuningrum Diana Soesilo, Diana Dzulfikri, Ahzahra Indah Fadila, Okta Mulia Nur Farizaldi, Reisya Irfanny Fiona Salim, Jennifer Firyasasty, Beffano Roziq Herdymunas Galih Sampoerno Ghozali Pangestu, Dede Halima, Siti Noorraida Handriutomo, Yosef Kevin Haq, Addina Ainul Hartanli, Audrey Luisa Ira Widjiastuti Jordana, Jesslyn Ketut Suardita, Ketut Kristanti Parisihni Kun Ismiyatin Lestari, Vita Masa, Maria Margaretha S. Nogo Monika Werdiningsih Mulyadi, Reyz Pasenda Namira, Safa Marety Nanik Zubaidah Nicholas Tandean, Jason Nirawati Pribadi Nurkhalidah, Binar Najwa Oktaria, Wanda Pasenda Mulyadi, Reyz Pramesty, Azzahra Kinaya Pratiwi, Dian Dwi Putra, Mohammad Gerald Athallah Rachmawati, Atika Nisaa Raftiani, Ardelia Sabrina Rahardia, Nabiela Rayhan, Rafialdi Sri Kunarti, Sri Syafaati, Lailatul Maghfiroh Tanzil, Muhammad Iqbal Vivian Widjaya, Olivia Wahab, Sofi Arnesti Widya Saraswati Wulandini, Raden Ajeng