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All Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science eJournal Kedokteran Indonesia Cermin Dunia Kedokteran
Menaldi Rasmin
Department Of Pulmonology And Respiratory Medicine Faculty Of Medicine, Universitas Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Respiratory Science

 1 
Multiple Possible Causes Of Dyspnea In An Unusual Pickwickian Syndrome On Covid-19 Pandemic: A Case Study Steven Jonathan; Menaldi Rasmin
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.44

Abstract

Introduction: Pickwickian Syndrome (PS) or obesity hypoventilation syndrome (OHS) is a diagnosis of exclusion with features of obesity, sleep disordered breathing, and chronic daytime hypercapnia. Patients with PS could present into general OSA or respiratory failure. We are presenting an unusual case of PS with acute respiratory failure resulting in organ failure and mortality. Case report: A 41-year-old male was admitted to hospital due to shortness of breath. He had a trouble sleeping; frequently awoke as the breathing briefly stopped and gasping. There were history of diabetes melitus (DM) and hypertension for >10 years, smoking with moderate Brinkman Index. Patient appeared to have somnolence, tachypnea, hypoxemia, morbid obesity. We assessed him as PS, bronchopneumonia, respiratory failure, pulmonary edema, hypertensive heart disease (HHD), DM, acute on CKD. We managed him with pharmacotherapy, oxygen (BiPAP), and hemodialysis. After transferred from ICU to regular ward, patient was suddenly apneic and CPR was performed; ended in mortality. Discussion: This unusual case (malignant OHS) was a subgroup among OHS with greater morbidity and multiorgan system dysfunction. There were multiple causes of dyspnea on our patient which concluded to a death case. There are three modalities of management in stable PS: positive airway pressure (PAP), weight reduction, and pharmacotherapy. The management of respiratory failure in PS mainly involved oxygen therapy in positive pressure. Conclusion: There were multiple causes of dyspnea in this patient. Optimal management of patient ought to treat not only the PS but also all the comorbidities.
Preoperative Assessment Prior to Lung Resection: How to Eliminate the Risk Dian Megawati; Menaldi Rasmin; Budhi Antariksa; Faisal Yunus
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.48

Abstract

Lung resection is part of the treatment of various lung diseases, both malignancy and infection. Although it has great benefits, lung resection can result in a variety of functional disorders that can affect the whole cardiopulmonary system. The mortality of these procedures is 2-4% in segmentectomy and 6-8% in lobectomy, while the mortality of pneumonectomy in the world is 11%. Good preoperative assessment of patients has been reported to have reduced mortality and morbidity after lung resection. Things that need to be considered to assess preoperative eligibility include age, lung function, cardiovascular fitness, nutrition, and performance status. The preoperative pulmonary tolerance assessment is divided into three stages: the first stage is the assessment of lung function and blood gas analysis, the second stage is to assess postoperative prediction of pulmonary function, and the third stage is to assess the maximum oxygen consumption per minute by doing a cardiopulmonary exercise test. Patients who have a good tolerance for lung resection are patients who have predictive postoperative force expiration volume one second (ppoFEV1) values more than 40%, predictive postoperative diffusion capacity of the lung for carbon monoxide (ppoDLCO) more than 50%, and maximum oxygen consumption (VO2 max) more than 15ml/kg/min.
Gut-Lung Axis Anggie Indari; Menaldi Rasmin; Ari Fahrial Syam
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.68

Abstract

Microbiota and the body's immune system have a two-way interaction that is interconnected. The microbiota plays a role in the formation and maturation of the immune system, on the other hand, the immune system shapes the composition and function of the microbiota. This interaction is important in maintaining the body’s immune system’s homeostasis. The human intestine contains various types of microbes that form the gut microbiota. Various studies have found that changes in the gut microbiota are associated with immunity in distal tissues such as the lung. This gives rise to the concept of a feedback relationship between the gut and lung organs called the gut-lung axis. Through this axis, changes in the composition of the gut microbiota not only cause abnormalities in the gut but also affect microbiota in the lungs and can cause disease. One of the important routes in the transmission of substances from the intestine is through the mesenteric lymphatics. Probiotics can help improve the gut’s defense mechanism. A high-fiber diet can also reduce pathogenic bacteria by increasing levels of short-chain fatty acids. Therefore, a healthy lifestyle is needed to maintain the balance of the microbiota.
Relationship Between Nutritional Status, Physical Activity, Type of Work and Smoking Activity with Fitness Level Measured by 6-Minute Walking Test on Non-staff Employees of Universitas Indonesia, Depok Menaldi Rasmin; Hilma Nur Faiza; Kemal Akbar Suryoadji; Neny Husnaini Zain; Sakinasha Siva Utami; Feni Fitriani Taufik; Dewi Friska; Nani Cahyani Sudarsono; Elisna Syahrudin
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.70

Abstract

Background: Fitness is inextricable to health and has a significant correlation with the habits and behaviour of individuals such as dietary practice, sedentary behaviour, physical activities, and smoking habits. Many ways can be used to assess an individual fitness level, one of them is using the 6-minute walking test. This study aims to find the correlation between smoking intensity, nutritional status, occupation, and physical activity with the fitness level of outdoor janitors in Universitas Indonesia, Depok. Method: The research method was the cross-sectional design. The determination of the subjects was carried out by a consecutive sampling method. The data obtained results from the assessment of nutritional status, occupation, physical activity, and smoking intensity, as well as result from the 6-minute walking test. Univariate data analysis was used to assess the distribution of subjects based on sociodemographics, nutritional status, physical activity, occupation, and smoking activity. Furthermore, categorical correlative tests used were Man-Whitney, Kruskal-Wallis, and Fisher's Exact test. Results: The subjects obtained are 109 outdoor janitors from UI, Depok in which 59.6% age 18-44 years old, and 56% are male. Based on the correlative test between the fitness level and the nutritional status, value of P=0.086, as value of P between the physical activity and the fitness level is 0.0523. No significant correlation between fitness level and occupation based on location of the job, duration of work and based on the work time (P=1.00; P=1.00; P=0.108) The correlation between smoking intensity with the fitness level has value of P=0.681. Conclusion: There is no significant correlation between nutritional status, physical activity, type of work, and smoking intensity with the fitness level as measured by the 6-minute walking test method for outdoor janitors of UI, Depok.
Continuing Monitoring in Respiratory Intensive Care Unit and Mortality in Patient Post Bronchoscopy Procedure Vina Fiqria; Kevin Aristyo; Rasmin Menaldi
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.92

Abstract

Background: Bronchoscopy is a relatively safe procedure in the diagnosis and therapy of lung disease, however in some cases complications can occur which lead to further monitoring in the intensive care or respiratory intensive care unit (RICU) and even lead to mortality. This study aimed to determine the need for intensive care unit monitoring and the risk factors that increase the need for intensive care unit monitoring followed by mortality after bronchoscopy procedure. Method: A retrospective data of consecutive bronchoscopy procedures in Persahabatan Hospital between July to December 2021. Results: From 410 patients underwent bronchoscopy procedures, there were 52 patients (12.6%) were admitted to RICU after bronchoscopy. From patients who were treated in RICU 3 (5.8%) of them died. Patients who died during monitoring in intensive care unit had an older mean age of 60.3 years. There were 2 (12.5%) died after bronchoscopy procedures with two or more intervention, 1 patients (3%) died in the group with one intervention. There were 2 patients (13.3%) died with two or more comorbidities and 1 patient (5.9%) died with one comorbid. In the group with diagnosis of malignancy, 3 patients (7.5%) died. Whereas in patients who were performed surgery during bronchoscopy there were 2 patients (20%) died and only 1 patient (2.4%) died without any surgery during bronchoscopy. Conclusion: Although bronchoscopy is a relatively safe procedure but the need of monitoring in intensive care after bronchoscopy procedures were relatively high and mortality quite high compare to previous study. Further research is needed to determine the risk factors that increase the need of continuing monitoring in intensive care unit followed by mortality after bronchoscopy procedure.  
The Evolution of Transbronchial Lung Biopsy Guidance Alatas, Mohammad Fahmi; Bies, Asri Liqditta; Prasenohadi, Prasenohadi; Soehardiman, Dicky; Aniwdyaningsih, Wahju; Elhidsi, Mia; Desianti, Ginanjar Arum; Reisa, Tina; Rasmin, Menaldi
Respiratory Science Vol. 5 No. 2 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i2.170

Abstract

Histological confirmation of lung lesions is necessary prior to determining further management. Imaging preparation is needed to find the biopsy site such as a computed tomography scan. Imaging helps to trace the position of lung lesions that are peripheral and not visualized by bronchoscope. However, along with the discovery of small lesions and peripheral location, two-dimensional imaging alone remains suboptimal. Therefore, to reach lung lesions peripherally would need to a guide through the bronchial. Subsequently, the method of guiding transbronchial biopsy evolved. Namely, real-time fluoroscopy, radial-probe endobronchial ultrasound, virtual bronchoscopy navigation and electromagnetic bronchoscopy navigation are guiding modalities with each of their advantages and disadvantages. Several biopsy modalities are used in combination to increase the accuracy of diagnosis. Careful analysis in planning and an understanding of the limitations and advantages of diagnostic modalities must be considered in deciding which method to choose.
Co-Authors Adang Bachtiar Agus Dwi Susanto Alatas, Mohammad Fahmi Altama Latona Sidarta Amien, Bagus Radityo Andre Prawira Putra Anggie Indari Aniwdyaningsih, Wahju Anwar Jusuf Ari Fahrial Syam Arifin Nawas Bies, Asri Liqditta Budhi Antariksa Desianti, Ginanjar Arum Desilia Atikawati Dewi Friska Dian Megawati Diyan Ekawati Elhidsi, Mia Elisna Syahrudin Erlina Burhan Ernita Akmal Faisal Yunus Faisal Yunus Fanny Michelle Filemon Suryawan Handjaja Hadiarto Mangunnegoro Hasibuan, Thariq Emyl Taufik Hilma Nur Faiza Ika Yunita Sari Kartikawati, Falah Kemal Akbar Suryoadji Kevin Aristyo Latona Sidarta, Altama Nani Cahyani Sudarsono Nani Cahyani Sudarsono Neny Husnaini Zain Nina Aspiah Novita Maulidiyah Prasenohadi Prasenohadi Prasenohadi Prasenohadi Prasenohadi, Prasenohadi Pusparini Kusumajati Putri Suci Rahardjo, Tri Apriliawan Bendarto Ratnawati Antaria Reisa, Tina Risa Febriana Rita Rogayah Sakinasha Siva Utami Saroyo, Yudianto Budi Soehardiman, Dicky Sri Indah Indriani Sri Wening Pamungkasningsih Steven Jonathan Taufik, Feni Fitriani Vina Fiqria Wahju Aniwidyaningsih Widhy Yudistira Nalapraya Widjanantie, Siti Chandra Wirya Sastra Amran Wiwien H. Wiyono Zulhadji, Harry Agustio Zuswayudha Sjamsu