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All Journal JURNAL PHOTON Collaborative Medical Journal (CMJ) Jurnal Kesehatan Islam : Islamic Health Journal Jurnal Pengabdian Masyarakat Multidisiplin Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Journal Delik Adpertisi
Santi Widiasari
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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PEMBERDAYAAN USAHA MIKRO KECIL MENENGAH (UMKM) CENDAWAN HOUSE KELURAHAN TEBING TINGGI OKURA KOTA PEKANBARU Syed Agung Afandi; Muhammad Arif; Santi Widiasari; Muslim Afandi
Jurnal Pengabdian Masyarakat Multidisiplin Vol 3 No 1 (2019): Oktober
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.553 KB) | DOI: 10.36341/jpm.v3i1.983

Abstract

Usaha Mikro Kecil Menengah (UMKM) memiliki peranan penting dalam perekonomian negara, baik dari sisi penciptaan lapangan kerja maupun dari sisi jumlah usaha. UMKM Cendawan House memiliki kendala dalam aktivitas usahanya berupa belum dimilikinya pembukuan yang baik, struktur, dan pembagian tugas sehingga berdampak pada tingkat produktivitas dan pemasaran produk yang dihasilkan. Berdasarkan latar belakang tersebut maka dilaksanakan kegiatan pengabdian dengan mitra pengabdian yakni UMKM Cendawan House yang berada di Kelurahan Tebing Tinggi Okura, Kecamatan Rumbai Pesisir, Kota Pekanbaru, Provinsi Riau. Kegiatan pengabdian yang dilakukan yakni pemberdayaan melalui sosialisasi manajemen usaha untuk mengatasi masalah manajemen UMKM Cendawan House. Hasil dari kegiatan ini adalah mitra memiliki pembukuan yang baik, struktur, dan pembagian tugas serta wewenang yang jelas yang kemudian juga berdampak positif terhadap peningkatan produksi dan pemesaran produk yang dihasilkan. Dari kegiatan ini disimpulkan bahwa permasalahan yang dihadapi mitra dapat diselesaikan setelah pelaksanaan kegiatan ini.
Antibacterial Activity of Bay Leaf (Syzygium polyanthum) Ethanol Extract on Escherichia coli Growth Eliya Mursyida; Raissa Almira; Santi Widiasari; Olvaria Misfa
Sistem Informasi Vol 12 No 1 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v12i1.3142

Abstract

Acute diarrhea is liquid stool with a frequency of more than 3 times a day and lasts less than 14 days. One of the most common causes of acute diarrhea is Escherichia coli. Diarrhea caused by bacteria can be treated with the use of antibiotics, but the relatively high intensity of antibiotic use causes various health problems, especially bacterial resistance. Therefore, the search for antibacterial agents derived from natural ingredients was carried out as an alternative treatment. Bay leaf (Syzygium polyanthum) is one of the natural ingredients that has the potential as an antibacterial because it contains active compounds such as essential oils, flavonoids (quercetin), saponins, tannins, and alkaloids. This study aimed to analyze the antibacterial activity of the ethanolic extract of bay leaves on the growth of Escherichia coli. This research uses the dilution method which aims to determine the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC). The results showed that the MIC value at a concentration of 200mg/ml and the MBC value at a concentration of 500mg/ml.
MEKANISME INHIBISI ANGIOTENSIN CONVERTING ENZYM OLEH FLAVONOID PADA HIPERTENSI Santi Widiasari
Collaborative Medical Journal Vol 1 No 2 (2018): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.777 KB)

Abstract

Sistem renin-angiotensin-aldosteron merupakan faktor utama dalam memelihara tekanan darah arteri. Salah satu sasaran komponennya adalah angiotensin-converting enzyme (ACE), yang merupakan zink terglikolisasi dipeptidil-karboksipeptidase yang fungsi utamanya adalah mengatur tekanan darah arteri dan keseimbangan elektrolit melalui sistem renin-angiotensin-aldosteron ini. Sejumlah ekstrak dan senyawa yang berasal dari tanaman telah terbukti secara in vitro sebagai ACE inhibitor. Efek yang menguntungkan ini secara umum dianggap berasal dari adanya molekul flavonoid, yang turunan senyawa kimia kompleksnya dapat mencapai ke dalam pusat aktif ACE. Flavonoid adalah kelompok senyawa alam dengan variabel struktur fenolik dan dapat ditemukan pada tumbuhan. Pada saat ini terdapat peningkatan minat pada potensi teraputik tanaman obat yang kemungkinan berkaitan dengan gugus phenolnya, khususnya flavonoid. Flavonoid telah dikonsumsi oleh manusia sejak lama. Flavonoid memiliki kemampuan biologi yang luas dalam menjaga kesehatan manusia dan membantu mengurangi resiko berbagai penyakit. Khususnya untuk efek anti hipertensi dari senyawa flovanol telah diteliti secara luas. Senyawa ini menghasilkan kemampuan untuk mengurangi stres oksidatif, menghambat aktifitas angiotensin converting enzim, meningkatkan relaksasi endotel pembuluh darah, mengatur signaling sel dan ekspresi gen. Kemampuan untuk menggunakan flavonoid sebagai ACE inhibitor dalam mengatur tekanan darah telah diteliti sejak beberapa dekade yang lalu dan hampir semua telah terbukti efektif dalam menekan kerja ACE.
PENGARUH PEMBERIAN SUSU KEDELAI TERHADAP TEKANAN DARAH PASIEN HIPERTENSI DI WILAYAH PUSKESMAS GARUDA KECAMATAN MARPOYAN DAMAI Santi Widiasari; Ilham Aditya Putra
Collaborative Medical Journal Vol 5 No 2 (2022): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v5i2.3256

Abstract

Hypertension is a health problem which one of the main concerns even in worldwide since this disease is a significant risk factor that leads to cardiovascular diseases such as heart attack, heart failure, stroke, and kidney disease. Hypertension is divided into two types based on the cause, primary hypertension and secondary hypertension. Some treatments that help lower blood pressure are by using drugs (pharmacotherapy) or by way of lifestyle modifications. Soybean (Glycine Max) is a type of functional food that contains nutrients such as isoflavones, saponins, lecithin and phytosterols which reduce the risk of cardiovascular disease. This study aims to analyze the effect of giving soy milk on blood pressure in hypertensive patients. This research method used a pretest-posttest design with a control group design. The sample in this study used a purposive sampling technique, the maximum size of the subjects in the study was 30 people. The results of the study in the intervention group showed that there was an effect of giving soy milk on blood pressure in hypertensive patients before and after with systolic blood pressure p=0.000 (p<0.05) and diastolic blood pressure p=0.002 (p<0.05).
PENGARUH PEMBERIAN SUSU KEDELAI KUNING (Glycine max (L.) Merr.) TERHADAP KADAR KOLESTEROL TOTAL PADA PRIA HIPERKOLESTEROLEMIA Santi Widiasari; Mutiara , Mutiara Muslimah; Eliya Mursyida
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 12 No. 2 (2023): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v12i2.20831

Abstract

Abstract.Hypercholesterolemia is an increase in blood cholesterol levels, which is more than 200 mg / dl. In Indonesia, 9.3% of the incidence of hypercholesterolemia is in productive age, namely the age range of 25-40 years. One of the drugs for hypercholesterolemic sufferers is a statin which is believed to reduce LDL levels and inhibit the formation of cholesterol by indirectly affecting cholesterol levels in the blood. Soybeans are known to reduce cholesterol levels because they contain isoflavones that bind to the endoplasmic reticulum, then increase the Low-density lipoprotein (LDL) receptors in the liver. So that LDL levels in plasma are measured to be low. Objective: To analyze the effect of giving soy milk on cholesterol levels in hypercholesterolemic men. Method: Experimental using the design "One-Group Pretest-Postest Design". The sample consisted of 10 men with hypercholesterolemia given 250 ml / day for 2 weeks. Results: The results showed a significant value of p <0.05. The average total cholesterol level in the provision of soy milk decreased by 6.2 mg / dl. Conclusion: The provision of soy milk has an effect on total cholesterol levels in hypercholesterolemic men. Kata Kunci antibakteri; Hiperkolesterolemia, kolesterol, susu kedelai
Efektivitas Curcumin Dalam Mengurangi Peradangan Pada Dermatitis Atopik Helga Pasadena; Santi Widiasari
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 2 (2025): Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i2.4881

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus, erythema, and impaired skin barrier function. Conventional treatments such as topical corticosteroids and calcineurin inhibitors effectively reduce inflammation but pose potential adverse effects that limit their long-term use. Consequently, natural-based alternatives like curcumin have gained increasing interest. Curcumin, a principal polyphenol in turmeric (Curcuma longa), is known for its anti-inflammatory, antioxidant, and immunomodulatory properties. Its mechanisms in AD involve the inhibition of the NF-κB signaling pathway, downregulation of proinflammatory cytokines (IL-4, IL-13, TNF-α), and enhancement of filaggrin and ceramide production, which are crucial for restoring skin barrier function. This study is a systematic review aimed at evaluating the efficacy of curcumin in alleviating AD-related inflammation based on recent clinical and experimental studies. The meta-analysis revealed that nano-curcumin formulations were more effective than conventional curcumin in reducing atopic skin lesions and transepidermal water loss (TEWL). Additionally, combining curcumin with emollients or essential oils exhibited synergistic effects in improving skin hydration and reducing inflammation. In conclusion, curcumin demonstrates significant potential as an adjuvant therapy for AD; however, further research is required to determine its long-term efficacy and safety profile in clinical applications.
Penundaan Kewajiban Pembayaran Utang dalam Kepailitan Berdasarkan Undang-Undang Nomor 37 Tahun 2004 Tentang Kepailitan Dan Penundaan Kewajiban Pembayaran Utang Santi Widiasari; Prayuti, Yuyut; Lany, Arman
Jurnal Delik ADPERTISI Vol. 3 No. 1 (2024): Januari 2024
Publisher : Jurnal Delik ADPERTISI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The main problem of this research is how to analyze the juridical pawn agreement at PT Pegadaian (Persero) Maros Branch. The subject matter is further broken down into several subproblems, namely how to implement the lien agreement at PT Pegadaian (Persero) Maros Branch and how the process of resolving the default of the lien agreement at PT Pegadaian (Persero) Maros Branch. This research is a type of qualitative field research. This research will be conducted by interviews with branch leaders, employees of PT Pegadaian (Persero) Maros Branch and customers of PT Pegadaian. This research uses a sociological legal approach, namely direct field research. Data collection is obtained from observation, interviews and questionnaires. Based on the results of the study, it was answered that the implementation of the pawn agreement at PT Pegadaian (Persero) Maros Branch has not been effective because there are still many customers who do not heed the implementation of the pawn agreement so that only 57% is carried out and the implementation of the lien agreement is not carried out 43% of the total percentage of 100%. Meanwhile, the process of resolving the default of the pawn agreement at PT Pegadaian (Persero) Maros Branch is 1) for customers who do not pay credit installments or maturity, PT Pegadaian will reprimand customers by calling, SMS, writing to customers and the last resort taken is by parate execution or auction, 2) regarding the provision of compensation for lost customer collateral by indemnifying them in full or in whole while damaged collateral can be done by paying compensation of 125% of the estimated value of goods listed in SBK or can be more in accordance with the agreement and policy of PT Pegadaian it self.
Co-Authors Afandi, Syed Agung Arman Lany, Arman Eliya Mursyida Eliya Mursyida Helga Pasadena Ilham Aditya Putra Muhammad Arif Muslim Afandi Mutiara , Mutiara Muslimah Olvaria Misfa Prayuti, Yuyut Raissa Almira