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All Journal IJEMS (Indonesian Journal of Environmental Management and Sustainability) Jurnal Kesehatan Prima JURNAL PHOTON Collaborative Medical Journal (CMJ) Nommensen Journal of Medicine Medfarm: Jurnal Farmasi dan Kesehatan Indonesian Journal of Pharmaceutical Education Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat
Olvaria Misfa
Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Abdurrab, Kota Pekanbaru, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Other

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Effectiveness of Spirulina platensis Extract on Wound Area and TNF-a Levels on Blood: Experimental Studies In Wistar Rats Made Artificially by Vulnus Scissum and Infected by Staphylococcus aureus Olvaria Misfa; Renni Yuniarti; Yan Wisnu Prajoko
Indonesian Journal of Environmental Management and Sustainability Vol. 4 No. 2 (2020): June
Publisher : Research Centre of Inorganic Materials and Complexs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.001 KB) | DOI: 10.26554/ijems.2020.4.2.55-58

Abstract

This research uses randomizedpost-test only control group design. Thirty-two (32) male Wistar rats with incised skin and infected with S. aureusdivided into 4 groups, namely the group given S.platensisextract at a dose of 500 mg / kgBB / day (X1) and a dose of 750 mg / kgBB / day (X2 ), the negative control group was given saline solution (C1), and the positive control group was given amoxicillin 150 mg / kg orally(C2). Wound area measurements were taken on day 14 and serum TNF-? levels were examined on day 14 using the ELISA method. Data analysis was performed with one way ANOVAtestand continued with Post Hoc Test LSD.The results showed mean size of wound closure on the 14th day in groups X1, X2, C1 and C2 is 8095.74; 6270.98;15502.69; 11475.20micrometer with p <0.001. The mean TNF-? serum levels in the 14th day of X1, X2, C1, and C2 groups were 270.75; 222.83; 1730.33; 385.75pg / ml with p <0.001. Post Hoc Test of wound area showed significant differences between groups. Post Hoc Test TNF-? levels showed significant differences between treatment groups X1 and X2 with group C1.Spirulina platensisextract 500mg / kgBB / day and 750 mg /kgBB/ day have the smallest wound area significantly and reduce TNF-? levels on blood.
Antibacterial Activity of Bay Leaf (Syzygium polyanthum) Ethanol Extract on Escherichia coli Growth Eliya Mursyida; Raissa Almira; Santi Widiasari; Olvaria Misfa
Sistem Informasi Vol 12 No 1 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v12i1.3142

Abstract

Acute diarrhea is liquid stool with a frequency of more than 3 times a day and lasts less than 14 days. One of the most common causes of acute diarrhea is Escherichia coli. Diarrhea caused by bacteria can be treated with the use of antibiotics, but the relatively high intensity of antibiotic use causes various health problems, especially bacterial resistance. Therefore, the search for antibacterial agents derived from natural ingredients was carried out as an alternative treatment. Bay leaf (Syzygium polyanthum) is one of the natural ingredients that has the potential as an antibacterial because it contains active compounds such as essential oils, flavonoids (quercetin), saponins, tannins, and alkaloids. This study aimed to analyze the antibacterial activity of the ethanolic extract of bay leaves on the growth of Escherichia coli. This research uses the dilution method which aims to determine the Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC). The results showed that the MIC value at a concentration of 200mg/ml and the MBC value at a concentration of 500mg/ml.
Efektivitas Ekstrak Spirulina platensis terhadap Jumlah Fibroblas pada Tikus yang Dilakukan Insisi pada Kulitnya Riski dwi utami; olvaria misfa; Bimby Irenesia; deinike wanita marwan
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.19268

Abstract

Fibroblasts play a role in the wound healing process. The active compound content of Spirulina sp. has fibroblastic activity. The use of extracts from S. platensis can play a role in the wound healing process. To analyze the effectiveness of Spirulina platensis extract on the number of fibroblasts in rats that were incised in their skin. This study used a randomized post test only control group design. Forty-eight male Wistar rats were skin incised and infected with S.aureus divided into 4 groups, namely the group given S.platensis extract at a dose of 500 mg/kgBW/day, a dose of 750 mg/kgBW/day, the negative control group was given saline solution and positive control group with diclofenac 20 mg/kgBW orally. The number of fibroblasts was counted on histopathological examination of the wound tissue on the 7th and 14th days covering 5 visual fields. Data analysis was carried out with a one way ANOVA test and continued with the LSD Post Hoc Test. The mean number of fibroblasts on the 7th day in the 500 mg/kgBW/day group, 750 mg/kgBW/day, positive control and negative control was 13.33 ± 3.615; 117.42±3.980; 9.58±2.417; and 4.00 ± 1.761 with p 0.001. The number of fibroblasts on the 14th day in the 500 mg/kgBW/day, 750 mg/kgBW/day group, positive control and negative control was 16.17 ± 3.251; 19.67±1.633; 12.17±2.137; and 8.33 ± 2.317 with p 0.001. The post hoc test found that the number of fibroblasts on day 7 significantly increased in the 500 mg/kgBB/day S. platensis group compared to the positive and negative control groups. While at a dose of 750 mg/kg/day, the number of fibroblasts was higher than the positive and negative control groups after 14 days of treatment.Administration of Spirulina platensis extract at doses of 500 and 750 mg/kg/day significantly increased the number of fibroblasts in the incision wounds of Wistar rats.
In Vitro Sensitivity Test of Escherichia coli ATCC 25922 to Various Antibiotics with Well Diffusion Method Eliya Mursyida; Olvaria Misfa; Sasa Billa Pratiwi; Akhilesh Shinde
Jurnal Kesehatan Prima Vol 17, No 2 (2023): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v17i2.1003

Abstract

Escherichia coli ATCC 25922 is an opportunistic normal flora bacteria that can cause diseases such as diarrhea and other intestinal tract diseases. Acute diarrhea is the discharge of loose/liquid stools with a frequency of more than 3 times a day or more lasting less than 14 days. Until now acute diarrheal infections are caused by Escherichia coli usually treated with antibiotics. However, it is known that there is resistance of Escherichia coli bacteria to several antibiotics such as ampicillin, tetracycline, sulfamethoxazole-trimethoprim, cotrimoxazole, chloramphenicol, ciprofloxacin, and gentamicin caused by controlled use of antibiotics. This study aims to analyze the sensitivity of various antibiotics to Escherichia coli ATCC 25922 bacteria in vitro. This research is an experimental study with a post-test only with control group research design and uses various antibiotics as samples. The test bacteria used in this study was Escherichia coli ATCC 25922, with the agar diffusion method (well). The diameter of the inhibition zone formed was measured using a caliper. The results of the sensitivity test of various antibiotics against Escherichia coli were found to be 5 resistants, namely sulfamethoxazole-trimethoprim 1.25µg (8,90mm), cefotaxime 30µg (12,26mm), cefixime 30µg (5,20mm), ceftriaxone 30µg (10,66mm), chloramphenicol 30µg (8,80mm), 3 intermediates namely ampicillin 10µg (16,00mm), gentamicin 10µg (13,55mm), erythromycin 15µg (17,53mm), and 2 sensitives, namely tetracycline 30µg (25,80mm), ciprofloxacin 5µg (23,31mm).
Pelatihan Self Exercise Untuk Mengurangi Nyeri Haid Pada Siswi Sekolah Menengah Atas Negeri 06 Pekanbaru Sari Triyulianti; Siti Muawanah; Nurmaliza Nurmaliza; Olvaria Misfa; Adinda Soleha
Jurnal Pengabdian Masyarakat: Pemberdayaan, Inovasi dan Perubahan Vol 4, No 6 (2024): JPM: Pemberdayaan, Inovasi dan Perubahan
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpm.v4i6.949

Abstract

Menstrual pain, or dysmenorrhea, is a common complaint frequently experienced by adolescent girls, characterized by lower abdominal pain that occurs before or during menstruation. This pain is generally caused by uterine muscle contractions due to the release of prostaglandins. This condition can affect quality of life, disrupt daily activities, and reduce concentration in school. Self-exercise is a non-pharmacological method that can be performed independently, offering benefits such as improving blood circulation and relieving muscle tension. This community service activity aimed to provide self-exercise training to reduce menstrual pain at Sekolah Menengah Atas Negeri 6 Pekanbaru, attended by 30 students. During the activity, questionnaires were used to collect data regarding the participants' experiences with menstrual pain and their usual pain management methods. Pretests and post-tests were conducted to measure changes in participants' understanding of menstrual pain and its management. Self-exercise guide brochures were distributed to support home practice. The results showed a significant increase in participants' understanding of menstrual pain management after the training. Before the education was provided, 6 participants (20%) had good knowledge, while 24 participants (80%) were in the moderate category. After the education, 28 participants (93.3%) demonstrated good knowledge, with only 2 participants (6.7%) remaining in the moderate category. Thus, empowering adolescent girls through self-exercise training proved effective in enhancing their understanding of menstrual pain management.ABSTRAKNyeri haid atau dismenore adalah keluhan umum yang sering dialami oleh remaja putri, yang ditandai dengan rasa sakit di perut bagian bawah yang terjadi sebelum atau selama menstruasi. Nyeri ini umumnya disebabkan oleh kontraksi otot rahim akibat pelepasan prostaglandin. Kondisi ini dapat memengaruhi kualitas hidup, mengganggu aktivitas sehari-hari, dan menurunkan konsentrasi belajar di sekolah. Self exercise merupakan metode non-farmakologis yang dapat dilakukan secara mandiri, dengan manfaat meningkatkan sirkulasi darah dan meredakan ketegangan otot. Kegiatan pengabdian masyarakat ini bertujuan memberikan pelatihan self exercise guna mengurangi nyeri haid di Sekolah Menengah Atas Negeri 6 Pekanbaru, yang dihadiri oleh 30 siswi. Selama kegiatan, kuesioner digunakan untuk mengumpulkan data mengenai pengalaman nyeri haid dan penanganan yang biasa dilakukan. Pretest dan post-test dilaksanakan untuk mengukur perubahan pemahaman peserta tentang nyeri haid dan cara penanganannya. Leaflet panduan self exercise dibagikan untuk mendukung praktik di rumah. Hasil menunjukkan bahwa pemahaman peserta mengenai penanganan nyeri haid meningkat secara signifikan setelah pelatihan. Sebelum diberikan edukasi, 6 orang (20%) memiliki pengetahuan yang baik, sementara 24 orang (80%) berada pada kategori sedang. Setelah diberikan edukasi, 28 orang (93,3%) menunjukkan pengetahuan yang baik, dan hanya 2 orang (6,7%) yang masih memiliki pengetahuan di kategori sedang. Dengan demikian, pemberdayaan remaja putri melalui pelatihan self exercise terbukti efektif dalam meningkatkan pemahaman remaja putri tentang penanganan nyeri haid.
EFEKTIVITAS GEL EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA TIKUS PUTIH YANG DIINFEKSI Staphylococcus aureus riski dwi utami; olvaria misfa; alfiza rahmanita; mahendra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2263

Abstract

The World Health Organization (WHO) estimates that around 180,000 deaths occur due to burns.  The healing process of burn wounds is influenced by several factors, such as the area, depth of the burn and infection. One of the bacteria that causes infection in burn wounds is Staphylococcus aureus. Starfruit leaf extract, used in gel form, is a natural remedy that offers benefits for burn treatment. This study aimed to analyze the effectiveness of starfruit leaf extract gel in healing burn wounds infected with Staphylococcus aureus in white rats. This research method was true experimental with a randomized posttest only control group design with 20 rats divided into four groups, namely the positive control group using bioplacenton (C1), the negative control group using gel base (C2), treatment group 1 with starfruit leaf extract gel with a concentration of 6% (P1) and group treatment 2 with starfruit leaf extract gel with a concentration of 12% (P2). The study found the smallest burn area on day 3 and day 7 was group C1 with an average of 2,799 cm2 and 2,324 cm2. On the 14th day it was group P2 with an average of 1,134 cm2. On the 21st day it was groups C1 and P2 with a mean of 0.163 cm2 and 0.164 cm2. The One-Way Anova test revealed significant differences in burn wound healing on days 3, 7, 14, and 21 (p < 0.05). Starfruit leaf extract gel effectively heals burns in white mice infected with S. aureus, with 12% concentration 
Efektivitas Ekstrak Spirulina platensis sebagai Antiinflamasi terhadap Jumlah Neutrofil dan Makrofag pada Luka yang Diinfeksi Staphylococcus aureus pada Tikus Wistar Misfa, Olvaria; Utami, Riski Dwi; Irenesia, Bimby; Marwan, Deinike Wanita
Nommensen Journal of Medicine Vol 8 No 1 (2022): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v8i1.735

Abstract

ABSTRAK Latar belakang: Kandungan senyawa aktif dari Spirulina sp. memiliki aktivitas antiinflamasi dan antibakteri. Penggunaan senyawa tersebut berperan dalam proses inflamasi pada luka yang terinfeksi. Tujuan: Menganalisis efektifitas pemberian ekstrak Spirulina platensis terhadap jumlah neutrofil dan makrofag pada luka insisi tikus wistar yang diinfeksikan S. aureus. Metode: Penelitian ini menggunakan randomized post test only control group design. Dua puluh empat ekor tikus wistar jantan diinsisi kulitnya dan diinfeksikan S.aureus dibagi menjadi 4 kelompok, yaitu kelompok yang diberi ekstrak S.platensis dosis 500 mg/kgBB/hari, dosis 750 mg/kgBB/hari, kelompok kontrol negatif diberi larutan salin serta kelompok kontrol positif dengan pemberian amoksisilin 150 mg/kgBB peroral. Jumlah neutrofil dan makrofag dihitung pada pemeriksaan histopatologis dari jaringan luka pada hari ke-14 yang mencakup 5 lapang pandang. Analisis data dilakukan dengan uji one way ANOVA dan dilanjutkan dengan Post Hoc Test LSD. Hasil: Rerata jumlah neutrofil hari ke-14 pada kelompok dosis 500 mg/kgBB/hari, 750 mg/kgBB/hari, kontrol positif dan kontrol negatif adalah 17,83; 12,17; 5,17; dan 8,83 dengan p < 0,001. Jumlah makrofag hari ke-14 pada kelompok dosis 500 mg/kgBB/hari, 750 mg/kgBB/hari, kontrol positif dan kontrol negatif adalah 7,17; 10,83; 16,83; 15,83 dengan p < 0,002. Uji Post Hoc menemukan jumlah neutrofil pada kelompok dosis 500 mg/kgBB/hari secara signifikan lebih tinggi dibandingkan kelompok lainnya. Sementara, uji Post Hoc untuk jumlah makrofag menemukan perbedaan signifikan hanya pada kelompok dosis 500 mg/kgBB/hari terhadap kelompok kontrol positif dan kontrol negatif. Simpulan: Pemberian ekstrak Spirulina platensis dosis 500mg/kgBB/hari secara signifikan meningkatan jumlah neutrofil dan menurunkan jumlah makrofag pada luka insisi tikus wistar yang diinfeksikan Staphylococcus aureus . Kata kunci: luka, makrofag, neutrofil, Spirulina platensis ABSTRACT Background: The active compound of Spirulina sp. has anti-inflammatory and antibacterial property. The use of these contents plays a role in the inflammatory process in infected wounds. Objective: To analyse the effectiveness of Spirulina platensis extract on the number of neutrophils and macrophages in the incision wound of Wistar rats infected by S. aureus. Methods: This study used a randomized posttest-only control group design. Twenty-four male Wistar rats had their skin incised and infected with S. aureus were divided into 4 groups. The group was given with the extract of S. platensis at a dose of 500 mg/kgBW/day (1), a dose of 750 mg/kgBW/day (2), the negative control group was given saline solution(3), and the positive control group was given amoxicillin 150 mg/kg body weight orally (4). The number of neutrophils and macrophages was counted on histopathological examination of the wound tissue on day 14 which included 5 visual fields. Data analysis was carried out by one way ANOVA test and followed by LSD Post Hoc Test . This study used a randomized posttest-only control group design. Twenty-four male wistar rats were divided into 4 groups, the groups were given S. platensis extract 500 mg/kgBW/day and 750 mg/kgBW/day, the positive control group was given amoxicillin 150 mg/kgBW orally and the negative control group was given saline solution. The skin of the mice was incised and infected with S. aureus. Histopathological examination of wound tissue was performed on day 14 to assess the number of neutrophils and macrophages. Data analysis was carried out with the oneway ANOVA test. Results: The mean numbers of neutrophils on the 14th day in the group of a dose of 500 mg/kgBW/day, 750 mg/kgBW/day, positive control, and negative control were 17.83; 12.17; 5.17; and 8.83 with p < 0.001, respectively. The numbers of macrophages on the 14th day in the group of a dose of 500 mg/kgBW/day, 750 mg/kgBW/day, positive control, and negative control were 7.17; 10.83; 16.83; 15.83 with p < 0.002, respectively. The Post Hoc test exhibited that the neutrophil count in the group of 500 mg/kgBW/day was significantly higher than the other groups. Meanwhile, the Post Hoc test for the number of macrophages found a significant difference, only in the group of a dose of 500 mg/kgBW/day against the positive and negative control groups. Conclusion: There was a significant decrease in the number of macrophages in the group of wistar rats that were incised and infected with Staphylococcus aureus and given Spirulina platensis extract at a dose of 500mg/kgBW/day. Keywords: wound, macrophages, neutrophils, Spirulina platensis
Sosialisasi dan Penanaman Tanaman Obat Keluarga (TOGA) dalam Upaya Peningkatan Kesehatan Masyarakat di RW 01 Sidomulyo Timur Misfa, Olvaria; Zulfikri, Rahmat; Juhana, Luthfi; Rahma Tri Cahyaningrum, Nanda; Febrianti, Nadia; Pebriayanti, Nursakina; Azzahra, Fitria; Dwi Lestari, Indah; Nurazlinda, Nurazlinda; Syaiful Umam, Moh
JDISTIRA - Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Vol. 3 No. 2 (2023)
Publisher : Yayasan Rahmatan Fidunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jdt.v3i2.540

Abstract

Tanaman obat keluarga (TOGA) merupakan tanaman hasil budidaya rumahan berkhasiat sebagai obat untuk kesehatan keluarga dan ditanam di lahan perkarangan rumah. TOGA dapat dijadikan alternatif sebagai obat aman, murah dan mudah didapat dalam memenuhi keperluan keluarga dalam melakukan perawatan kesehatan secara mandiri dalam kehidupan sehari-hari. Kegiatan pengabdian ini dilaksanakan dengan melakukan sosialisasi dan penanaman tanaman obat bersama ibu-ibu Pemberdayaan Kesejahteraan Keluarga (PKK) yang ada di RW. 01 Kelurahan Sidomulyo Timur, Kecamatan Marpoyan Damai, Kota Pekanbaru. Tujuan dilakukan kegiatan ini untuk meningkatkan kesadaran terkait pemanfaatan lahan, salah satunya dengan menanam tanaman obat agar masyarakat dapat memelihara kesehatan dan mengatasi gangguan kesehatan ringan secara mandiri. Sosialisasi dilakukan untuk memberikan informasi kepada ibu-ibu PKK terkait manfaat tanaman obat sebagai upaya dalam peningkatan kesehatan dan dilanjutkan dengan kegiatan penanaman TOGA yang telah dipilih. Hasil dari pengabdian masyarakat ini, ibu-ibu PKK telah mengetahui manfaat dari TOGA sebagai tanaman berkhasiat obat yang dapat diperoleh dengan mudah.
Formulation and Antibacterial Evaluation of Liquid Soap Containing Pineapple Peel Extract Against Staphylococcus aureus and Streptococcus pyogenes Eliya Mursyida; Frengki Molek Wirajaya; Olvaria Misfa
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.765

Abstract

The increasing prevalence of antimicrobial resistance highlights the need for alternative antibacterial agents, particularly against Gram-positive pathogens such as Staphylococcus aureus and Streptococcus pyogenes. Pineapple peel (Ananas comosus (L.) Merr.), an agricultural by-product, contains bioactive compounds with reported antimicrobial activity. This study aimed to formulate ethanol extract of pineapple peel into a liquid soap and evaluate its physicochemical properties and antibacterial effectiveness. The extract was incorporated at concentrations of 5%, 10%, and 15%. Physicochemical evaluations included organoleptic properties, homogeneity, pH, free alkali content, and specific gravity. Antibacterial activity was determined using the agar well diffusion method against S. aureus and S. pyogenes. All formulations met general quality requirements for liquid soap preparations, with pH values ranging from 7.3 to 9.7, specific gravity between 1.01 and 1.04g/mL, and free alkali content ≤0.1%. Antibacterial testing demonstrated a concentration-dependent increase in inhibition zone diameter. The 15% formulation exhibited the highest activity, producing inhibition zones of 13.30mm against S. aureus and 20.25mm against S. pyogenes, with statistically significant differences compared to lower concentrations (p < 0.05). These findings indicate that pineapple peel extract can be successfully incorporated into a stable liquid soap formulation while retaining its antibacterial activity. The 15% formulation shows promising potential as a natural-based antibacterial cleansing product.
UJI AKTIVITAS ANTIFUNGI BAKTERI ASAM LAKTAT ASAL DADIH TERHADAP Fusarium oxysporum Yudiawati Yudiawati; Olvaria Misfa; Eliya Mursyida; Riski Dwi Utami
Collaborative Medical Journal Vol 5 No 2 (2022): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v5i2.3253

Abstract

Intoksikasi mikotoksin pada manusia disebabkan oleh makanan yang dikonsumsi dan merupakan inhibitor poten terhadap sintesis protein, RNA, dan DNA. Fusarium oxysporum merupakan salah satu spesies penyebab intoksikasi mikotoksin yang ditularkan melalui makanan. Mikroba yang umumnya digunakan untuk eliminasi mikotoksin adalah bakteri asam laktat (BAL) yang bersumber dari makanan fermentasi seperti dadih yang berasal dari fermentasi susu kerbau. Tujuan penelitian ini untuk menguji aktivitas antifungi BAL terhadap pertumbuhan F. oxysporum dan menggunakan desain post-test only with control group. Aktivitas BAL terhadap F. oxysporum diuji menggunakan metode sumuran. Data yang diperoleh dianalisis menggunakan uji One Way ANOVA dan uji Post Hoc Bonferroni. Hasil isolasi BAL dari dadih adalah bakteri Gram positif berbentuk bacil dan coccobaci dengan uji katalase negatif. Diameter zona hambat BAL 1, BAL 2, dan BAL 3 yaitu 9,10 mm, 8,30 mm, 7,33 mm. Hasil uji One Way ANOVA menunjukkan terdapat perbedaan bermakna antara ketiga isolat BAL dalam menghambat pertumbuhan F. oxysporum. Hasil uji Post hoc Bobferroni menunjukkan kontrol positif terdapat perbedaan yang bermakna dengan BAL 1, BAL 2, dan BAL 3. Sedangkan, hasil BAL 1, BAL 2, dan BAL 3 tidak terdapat perbedaan bermakna pada kelompok perlakuan. Hasil menunjukkan bahwa tiga isolat BAL mampu menghambat pertumbuhan Fusarium oxysporum.
Co-Authors Adinda Soleha Akhilesh Shinde alfiza rahmanita Andre Andre Azzahra, Fitria Bellanera Alifia Safitri Bimby Irenesia Dwi Lestari, Indah Eliya Mursyida Eliya Mursyida Febrianti, Nadia Frengki Molek Wirajaya Huda Marlina Wati Huda Marlina Wati Irenesia, Bimby Juhana, Luthfi Mahendra Mahendra Mahendra Marwan, Deinike Wanita Nurazlinda, Nurazlinda Nurmaliza Nurmaliza Pebriayanti, Nursakina Rahma Tri Cahyaningrum, Nanda Raissa Almira Ranti Novita Sari Ratih Ayuningtiyas Renni Yuniarti Riski dwi utami Riski Dwi Utami Riski Dwi Utami Sabrina Hayati Sandra Putri Yulita Santi Widiasari Santi Widiasari Sasa Billa Pratiwi Siti Muawanah Syaiful Umam, Moh Triyulianti, Sari Uly Astuti Siregar Utami, Riski Dwi Viola Anggraini Asrizal Yan Wisnu Prajoko Yudiawati Yudiawati Zulfikri, Rahmat