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Chemistry Education Department, Khairun University, Jl. Bandara Babullah, Ternate 97728 Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Education Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Efektivitas Praktikum Berbasis Chemlab Terhadap Science Process Skills Mahasiswa Abd Wahid Hi Hasan; Deasy Liestiyanti; Muliadi -
Jurnal Pendidikan Kimia Unkhair (JPKU) Vol 1 No 1 (2021): Jurnal Pendidikan Kimia Unkhair (JPKU)
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jpku.v1i1.5048

Abstract

AbstrakPenelitian ini dilakukan untuk mengetahui efektivitas praktikum kimia berbasis Virtual Laboratory terhadap Science Process Skills mahasiswa program studi pendidikan kimia semester I TA 2020/2021. Jenis penelitian ini adalah penelitian deskriptif kuantitatif. Teknik penentuan sampel menggunakan teknik sampling jenuh pada 34 mahasiswa program studi pendidikan kimia yang mengampuh matakuliah praktikum kimia dasar I. Instrumen yang digunakan dalam penelitian ini berupa Lembar Kerja Mahasiswa Praktikum (LKMP) dan angket. Setelah dilakukan penelitian, data yang diperoleh diolah dan dianalisis menggunakan uji interval skala. Hasil analisis menunjukkan Science Process Skills mahasiswa kurang baik (56,67) dan praktikum kimia berbasis Virtual Laboratory terhadap Science Process Skills mahasiswa Cukup Efektif dengan nilai peroleh rata-rata  57%. Kata Kunci :       Mahasiswa pendidikan kimia, Virtual Laboratory, Science Process Skills, Titrasi asam basa Abstract The digitization of the education sector is inevitable because it can streamline the learning process and practicum without the boundaries of tools and space. Chem-Lab is one of the Virtual Laboratory software that provides various practicum simulations. This study aims to determine the effectiveness of the acid-base titration practicum using the Chem-Lab Software for students of the chemistry education study program semester I of 2020/2021. The research data was tested using the scale interval test. The results of the analysis showed that the students 'Science Process Skills were not good enough (56.67) and the Virtual Laboratory-based chemistry practicum towards the students' Science Process Skills was quite effective with an average score of 57%. Keywords:Chem-Lab and Science Process Skills 
Analisis Hubungan Kuantitatif Antara Struktur Dengan Aktivitas Antimikroba Streptococcus mutans Penyebab Sakit Gigi Menggunakan Senyawa Turunan Eugenol Ike Dwi Setiani; Muliadi -; Nur Asbirayani Limatahu
Jurnal Pendidikan Kimia Unkhair (JPKU) Vol 1 No 2 (2021): Jurnal Pendidikan Kimia Unkhair (JPKU)
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jpku.v1i2.5096

Abstract

AbstrakPenelitian ini bertujuan untuk mengetahui pemodelan struktur senyawa turunan eugenol menggunakan metode HKSA (Hubungan Kuantitatif Struktur dan Aktivitas) dan untuk mengetahui aktivitas antimikroba senyawa turunan eugenol pada bakteri Streptococcus mutans. Pemodelan struktur molekul telah dilakukan secara komputasi dengan menggunakan software ChemDraw Ultra 12.0. Hasil optimasi  menggunakan metode semi empiris AM1 menghasilkan energi total dan panas pembentukan dari masing-masing senyawa turunan eugenol. Perhitungan hubungan antara deskriptor (elektronik, hidrofobik, dan sterik) dengan aktivitas antimikroba dilakukan dengan menggunakan analisis korelasi yang terdapat dalam program IBM SPSS 25. Hasil analisis menunjukkan terdapat adanya hubungan antara deskriptor dengan antivitas antimikroba (Log P) yaitu EHOMO, ELUMO, Gap, MD, Polarizability, PSA, MSA, Idenks Harary, Indeks Randic, Indeks Weiner, qC1, qC2, qC3, qC6, qC7, dan qC8. Penentuan model persamaan HKSA terbaik dilakukan dengan menganalisis regresi linear berganda menggunakan paket program IBM SPSS 25. Hasil analisis yang didapatkan untuk model persamaan HKSA terbaik terdapat pada persamaan model 1 : Log P = 0.149 - (11.299) qC8 – (9.190) qC2 + (0.163) Polarizability – (6.720) ELUMO – (0.783) MD dengan n = 7, R = 0.999, R2 = 0.998, SE = 0.07399. Kata Kunci :       Eugenol, Hubungan Kuantitatif Struktur dan Aktivitas, Austin Model-1, Antimikroba, Streptococcus mutans Abstract This study aims to determine the structural modeling of eugenol derivative compounds using the QSAR (Quantitative Structure Activity Relationship) method and to determine the antimicrobial activity of eugenol derivative compounds in Streptococcus mutans bacteria. Molecular structure model have been done with computationally using ChemDraw Ultra 12.0 software. The optimization results using the AM1 semi-empirical method produce the total energy and ordered heat of each eugenol derivative. The calculation of the relationship between descriptors (electronic, hydrophobic, and steric) with antimicrobial activity was performed using correlation analysis contained at IBM SPSS 25 program. The results of correlation analysis there was showed relationship between descriptors with antimicrobial activity (Log P) such as: EHOMO, ELUMO, Gap, MD, Polarizability, PSA, MSA, Harary's Idenks, Randic Index, Weiner Index, qC1, qC2, qC3, qC6, qC7, and qC8. Determination the best model of QSAR equation of performed by analyzing multiple linear regression using IBM SPSS 25 program package. The results of analysis multiple linear regression obtained for the best QSAR equation model found in model 1 equation. Log P = 0.149 - (11.299) qC8 – (9.190) qC2 + (0.163) Polarizability – (6.720) ELUMO – (0.783) MD with n = 7, R = 0.999, R2 = 0.998, SE = 0.07399.Keywords:Eugenol, Quantitative Structure Activity Relationship, Austin Model-1, Antimicrobial, Streptococcus mutans
Co-Authors Abd Wahid Hi Hasan Adiba Arief Bikash Chandra Sarker Dhurbo Ronjon Roy Fahria salamat Fitriana Ibrahim Ike Dwi Setiani Ike Dwi Setiani Khadijah Khadijah Liestianty, Deasy Masud, Abdu Md. Humayun Kabir Md. Sirajul Islam Muhammad Amin Neni Abd Hamid Nur Asbirayani Limatahu Nurfatimah Sugrah Rasmi A Sangaji Setiawan, Topan Shamim Al Mamun Sundari Sundari Tanmoy Roy Tusher Topan Setiawan