Rima Novirianthy
Departemen Radiologi Fakultas Kedokteran Universitas Syiah Kuala, RSUD Dr. Zainoel Abidin, Banda Aceh

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Stereotactic Radiosurgery pada Benign Skull Base Tumor KODRAT, HENRY; NOVIRIANTHY, RIMA
Indonesian Journal of Cancer Vol 10, No 1 (2016): Jan - Mar 2016
Publisher : Indonesian Journal of Cancer

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Abstract

ABSTRACTTotal removal is difficult to be performed in skull base tumors because its location is surrounded by important structures such as nerves and blood vessels. Therefore, radiotherapy is one of treatment modalities that has been proven efficacy. Simultaneous with the development of imaging technology and advancement of radiobiology, radiosurgery is an emerging therapeutic modality. Radiosurgery is radiotherapy method which delivers high doseirradiation in single fraction. Rational use of stereotactic radiosurgery on benign skull base tumor is from radiobiology point of view; there is no advantage can be achieved from conventional dose fractionated radiotherapy compared with high dose. However, if we want to delivered high dose radiation, we must apply rigid immobilization, target definition using stereotactic navigation and image guidance verification. Radiosurgery can only be delivered in small intracranial lesion.ABSTRAKReseksi total kadang sulit dilakukan pada tumor yang terletak pada dasar tengkorak. Hal ini disebabkan lokasinya dikelilingi oleh struktur saraf dan pembuluh darah penting. Oleh karena itu, radioterapi merupakan salah satu modalitas terapi yang sudah terbukti maanfaatnya. Sejalan dengan perkembangan teknologi pencitraan dan kemajuan pengetahuan radiobiologi, radiosurgery merupakan modalitas terapi yang melejit penggunannya. Radiosurgery adalah metode pemberian radioterapi dengan dosis tinggi dan diberikan dalam fraksi tunggal. Rasional penggunaan stereotactic radiosurgery pada tumor jinak dasar tengkorak adalah karena dari sudut pandang radiobiologi, tidak ada kelebihan dariradioterapi dengan dosis konvensional dibandingkan dengan dosis tinggi. Namun, untuk pemberian dosis tinggi diwajibkan imobilisasi yang rigid dan lokalisasi yang akurat dengan menggunakan navigasi stereotaktik dan verifikasi dengan panduan pencitraan radiologi. Radiosurgery hanya dapat diberikan pada kelainan intrakranial yang berukuran kecil.
Stereotactic Radiosurgery in Recurrent Brain Metastases After Prior Radiosurgery: A Case Report and Review of Literature KODRAT, HENRY; NOVIRIANTHY, RIMA
Indonesian Journal of Cancer Vol 10, No 4 (2016): October - December 2016
Publisher : Indonesian Journal of Cancer

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Abstract

ABSTRACTPreviously, all brain metastasis has been treated with whole brain radiotherapy and the survival is poor. Recently, the development of stereotactic radiosurgery (SRS) provides comparable efficacy with low toxicity, and in several cases have a better survival compared to historical data. We conducted a case review in brain metastasis, which has been treated with SRS previously and experienced distant brain recurrence, then re-treated with SRS.ABSTRAKDahulu, semua metastasis otak ditangani dengan modalitas radiasi seluruh otak dan memiliki kesintasan yang tidak terlalu baik. Saat ini berkembang modalitas stereotactic radiosurgery (SRS). SRS memberikan efektivitas yang sebanding dengan toksisitas yang rendah dan pada beberapa kasus memiliki kesintasan yang lebih baik dibandingkandata sebelumnya. Berikut adalah tinjauan kasus metastasis otak dengan penanganan SRS sebelumnya dan mengalami kekambuhan di lokasi lain pada otak, kemudian ditatalaksana ulang dengan SRS.
Stereotactic Radiosurgery for Classical Trigeminal Neuralgia Kodrat, Henry; Novirianthy, Rima
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Trigeminal neuralgia is a debilitating pain syndrome with a distinct symptom mainly excruciating facial pain that tends to come and go unpredictably in sudden shock-like attacks. Medical management remains the primary treatment for classical trigeminal neuralgia. When medical therapy failed, surgery with microvascular decompression can be performed. Radiosurgery can be offered for classical trigeminal neuralgia patients who are not surgical candidate or surgery refusal and they should not in acute pain condition. Radiosurgery is widely used because of good therapeutic result and low complication rate. Weakness of this technique is a latency period, which is time required for pain relief. It usually ranges from 1 to 2 months. This review enlightens the important role of radiosurgery in the treatment of classical trigeminal neuralgia.
Peranan Radiosurgery pada Berbagai Kelainan Intrakranial Kodrat, Henry; Novirianthy, Rima
Cermin Dunia Kedokteran Vol 43, No 8 (2016): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (706.013 KB) | DOI: 10.55175/cdk.v43i8.99

Abstract

Radiosurgery merupakan modalitas klinik yang makin banyak digunakan dalam tatalaksana berbagai kelainan intrakranial. Hal ini didukung oleh perkembangan teknologi pencitraan MRI yang sangat membantu dalam penentuan target, perkembangan ilmu radiobiologi, perkembangan teknologi komputer yang sangat membantu dalam ketepatan navigasi stereotaktik, dan penemuan metode imobilisasi yang tidak invasif. Radiosurgery dapat digunakan dalam tatalaksana berbagai kelainan antara lain tumor jinak, metastasis otak, malformasi arteriovenosa, dan neuralgia trigeminal. Efek terapi radiosurgery ini cukup memuaskan dengan risiko komplikasi rendah.
Profil Ketuban Pecah Dini pada Ibu Bersalin di RSUD Dr. Zainoel Abidin Banda Aceh Rima Novirianthy; Safarianti Safarianti; Maimun Syukri; Cut Meurah Yeni; Muhammad Ikhsan Arzda
Jurnal Kedokteran Syiah Kuala Vol 21, No 3 (2021): Volume 21 Nomor 3 Desember 2021
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v21i3.21299

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Abstrak. Angka Kematian Ibu (AKI) merupakan salah satu indikator keberhasilan suatu negara dalam bidang kesehatan. Salah satu penyebab kematian pada ibu adalah infeksi. Ketuban Pecah Dini (KPD) merupakan salah satu penyebab tersering infeksi. Tujuan dari penelitian ini yaitu untuk mengetahui profil KPD pada ibu bersalin di RSUDZA Banda Aceh tahun 2019-2020. Metode penelitian ini berupa penelitian deskriptif dengan menggunakan data retrospektif. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 579 rekam medis pasien yang diambil dengan metode total sampling. Analisis data yang digunakan ialah analisis univariat untuk melihat profil pasien KPD. Hasil penelitian menunjukkan bahwa dari 579 sampel pasien KPD sebagian besar sampel berusia 20-35 tahun (79,3%), status pekerjaan sebagai IRT (81,3%), usia kehamilan aterm (77,2%), status nullipara (36,8%), mengalami leukosituria (52,9%), anemia (54,9%), kehamilan tunggal (98,4%), janin presentasi kepala (89,8%), lama KPD ≥ 12 jam (53,9%), dan metode persalinan sectio caesarea (66%). Kesimpulan penelitian ini menunjukkan bahwa KPD banyak terjadi pada ibu nullipara yang berusia 20-35 tahun dengan usia kehamilan aterm serta mengalami leukosituria dan anemia, oleh karena itu tenaga medis perlu memberikan edukasi terkait faktor risiko dan upaya pencegahan KPD. Kata Kunci : Ketuban Pecah Dini (KPD), Profil, RSUDZA Banda  AcehAbstract. Maternal Mortality Rate (MMR) is acknowledge as one of the country’s health sector development. Infection is one of the cause of maternal mortality. Premature Rupture of Membranes (PROM) is the most cause of infection. The objective of this research is to identify the profile of premature rupture of membranes on mother who gave birth in RSUDZA Banda Aceh year of 2019-2020. The method of this research is descriptive using retrospective data. The number of samples used in research is 579 medical records taken using total sampling method. Data analysis used is univariate analysis to find the profile of premature rupture of membrane patient. The result showed that out of 579 samples of patient with premature rupture of membrane are mostly aged between 20-35 years old (79,3%), occuption status as housewife (81,3%), gestation age of aterm (77,2%), nulliparous status (36,8%), leukocyturia (52,9%), anemia (54,9%), single preganancy (98,4%), fetal head presentation (89,9%), PROM duration ≥ 12 hours (53,9%), and the method delivery by sectio caesarea (66%). The conclusion of thin study showed that PROM occurs mostly in nulliparous who are 20-35 years old with aterm gestational age and have leukocyturia and anemia; therefore, medical personnel need provide education related risk factor and efforts to prevent PROM.Keywords : Premature Rupture of Membranes (PROM), Profile, RSUDZA Banda Aceh
Teknik Radiosurgery Henry Kodrat; Rima Novirianthy
Radioterapi & Onkologi Indonesia Vol 7, No 2 (2016): Volume 7 No.2 Juli 2016
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1285.667 KB) | DOI: 10.32532/jori.v7i2.47

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Stereotactic radiosurgery (SRS) merupakan teknik radioterapi lanjutan yang menggunakan prinsip navigasi stereotaktik untuk penentuan target radiasi, pencitraan 3 dimensi untuk pendefinisian target dan pemberian radiasi dosis tinggi dalam fraksi tunggal yang bersifat ablatif. Modalitas terapi ini banyak digunakan untuk tatalaksana berbagai kelainan Intrakranial karena bersifat non-invasif. SRS dapat diberikan dengan berbagai alat dan teknik. Tujuan artikel ini untuk memberikan gambaran umum berbagai teknik SRS disertai keuntungan dan kerugian dari masing-masing teknik.
ITEM ANALYSIS AND PEER-REVIEW EVALUATION OF SPECIFIC HEALTH PROBLEMS AND APPLIED RESEARCH BLOCK EXAMINATION Novi Maulina; Rima Novirianthy
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 9, No 2 (2020): July
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.49006

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Background: Assessment and evaluation for students is an essential component of teaching and learning process. Item analysis is the technique of collecting, summarizing, and using students’ response data to assess the quality of the Multiple Choice Question (MCQ) test by measuring indices of difficulty and discrimination, also distracter efficiency. Peer review practices improve quality of assessment validity in evaluating student performance.Method: We analyzed 150 student’s responses for 100 MCQs in Block Examination for its difficulty index (p), discrimination index (D) and distractor efficiency (DE) using Microsoft excel formula. The Correlation of p and D was analyzed using Spearman correlation test by SPSS 23.0. The result was analyzed to evaluate the peer-review strategy.Results: The median of difficulty index (p) was 54% or within the range of excellent level (p 40-60%) and the mean of discrimination index (D) was 0.24 which is reasonably good. There were 7 items with excellent p (40–60%) and excellent D (≥0.4). Nineteen of items had excellent discrimination index (D≥0.4). However,there were 9 items with negative discrimination index and 30 items with poor discrimination index, which should be fully revised. Forty-two of items had 4 functioning distracters (DE 0%) which suggested the teacher to be more precise and carefully creating the distracters.Conclusion: Based on item analysis, there were items to be fully revised. For better test quality, feedback and suggestions for the item writer should also be performed as a part of peer-review process on the basis of item analysis.
Treatment acceptance and its associated determinants in cancer patients: A systematic review Novirianthy, Rima; Syukri, Maimun; Gondhowiardjo, Soehartati; Suhanda, Rachmad; Mawarpury, Marty; Pranata, Agung; Renaldi, Teuku
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.197

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Treatment recommendations for cancer patients are carried out according to clinical assessment, type and stage of cancer and treatment guidelines. However, many patients do not accept the recommendations. This raises obstacles in managing of cancers, which not only affects the patients, but also the family and people around the patients. This problem could increase morbidity, mortality and recurrence rate, which might result in lower quality of life. Since this condition is a complex problem, there is necessity to explore and determine various determinants from different levels. The aim of this systematic  review was to explore the acceptances of cancer treatments among cancer patients and its associated determinants. Articles published from 2010 to 2023 were searched in four databases: ScienceDirect, Medline, Google Scholar and PubMed. Articles written in English and focussing on three main cancer treatments (surgery, chemotherapy and radiotherapy) were eligible.  A narrative approach was used and the data were analysed into selected themes. Data suggest that several factors influence patient acceptance for cancer therapy including sociodemographic, economic and spiritual cultural backgrounds; patient knowledge and perceptions; community support, as well as policy and availability of health facilities.  The determinants consist of individual, interpersonal, institutional, community and public policy level and interaction between levels are contributing to cancer treatment acceptance. In conclusion, cancer treatment acceptance remains a problem in particular in low middle income countries. In addition, the data on radiotherapy referral acceptance were limited and needed further study.
Palliative radiotherapy for leptomeningeal metastases after photon-based intensity-modulated radiotherapy in a nasopharyngeal cancer patient Marlina, Yoke S.; Novirianthy, Rima; Beočanin, Anđelija
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.266

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Leptomeningeal metastasis is a rare in nasopharyngeal carcinoma, affecting less than 5% of patients with a poor prognosis. The aim of this case report was to present management of palliative radiotherapy in leptomeningeal metastasis of nasopharyngeal carcinoma patient. A 33-year-old female presented with nasopharyngeal carcinoma with stage III, T3N3M0, WHO type III. The patient has received chemoradiation with photon-based intensity-modulated radiotherapy (IMRT) technique at the dose of 70 Gy in 33 fractions and showed a satisfactory outcome in 12 months follow-up. Later, at 18 months after chemoradiation completion, the patient complained of worsening bilateral sciatic pain, particularly during coughing, with slight limitations in bilateral hip flexion observed during straight leg raises. The whole spine contrast-enhanced magnetic resonance imaging (MRI) examination showed nodular enhancement of leptomeningeal thickening at the T4 level of the spinal cord lower than S3. Palliative radiation therapy utilized a three-dimensional conformal radiation therapy (3D-CRT) technique producing 35 Gy in 14 fractions placed in a field spanning the T4-S3 vertebral bodies. Methotrexate was administered intravenously every two weeks for three cycles to ensure central nervous system penetration. After four months of follow-up, no evidence of disease was found at the primary site and metastatic areas on subsequent physical examination or imaging with MRI and there was satisfactory improvement in neurologic symptoms. In conclusion, leptomeningeal metastases with primary nasopharyngeal carcinoma are rare and typically cause neurological impairments in patients. Hematogenous or cerebrospinal fluid-mediated spread of the cancer is considered the most likely pathway for leptomeningeal dissemination. Strategic modalities, such as radiotherapy with chemotherapy, may improve outcomes in symptoms and quality of life.
DETEKSI DINI TUMOR PAYUDARA DENGAN SADARI DAN PENAPISAN DENGAN ULTRASONOGRAFI DI KOTA BANDA ACEH Yus, Teuku Muhammad; Novirianthy, Rima; Zakaria, Iskandar; Machillah, Nurul; Dwi Susanti, Nurhayani; Zulkarnain, Zulkarnain; Suhanda, Rachmad
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 12 No 1 (2025): Januari
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v12i1.7974

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Kanker payudara salah satu kanker yang paling banyak ditemui pada perempuan di seluruh dunia. Kemenkes RI melaporkan bahwa dari sekitar 26.550 wanita usia 30-50 tahun yang memiliki benjolan pada payudara, 17,64% diantaranya dicurigai kanker payudara. Sementara di Provinsi Aceh dari 1285 wanita usia yang sama dan memiliki keluhan benjolan payudara, 54,1% dicurigai kanker payudara. Kanker payudara menempati peringkat kedua kematian akibat kanker di Indonesia. Angka mortalitas tersebut diperparah dengan fakta bahwa dari 80% kasus kanker payudara di Indonesia terdeteksi saat stadium lanjut. Menanggapi permasalahan tersebut, kami menyelenggarakan penyuluhan metode pemeriksaan payudara sendiri (SADARI) dan dilanjutkan penapisan dengan pemeriksaan ultrasonografi. Tujuan kegiatan ini untuk meningkatkan pengetahuan dan kesadaran masyarakat terhadap pentingnya deteksi dini kanker payudara dan pemeriksaan ultrasonografi payudara. Kegiatan ini melibatkan residen Prodi Radiologi FK USK, Banda Aceh. Hasil pemeriksaan ultrasonografi 12 peserta, 41,67% dengan keluhan dan 58,33% tanpa keluhan, 25% memiliki lesi di payudara dan 75% tidak ditemukan lesi.