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All Journal Jurnal Kedokteran Brawijaya Acta Interna : The Journal of Internal Medicine Jurnal Kesehatan Masyarakat Indonesian Journal of Biotechnology Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Wasilah Rochmah
Geriatric Department, RSUP DR. Sardjito Hospital,Yogyakarta, Indonesia.
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Association between Zinc Serum Level And CD4+ Count In Healthy Elderly Women At AISYIAH Elderly Club Kota Gede Yogyakarta Husni, Niko Adhi; Rochmah, Wasilah; Atmodjo, Suhardi Darmo
Acta Interna The Journal of Internal Medicine Vol 2, No 1 (2012): Acta Interna The Journal of Internal Medicine
Publisher : Acta Interna The Journal of Internal Medicine

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ABSTRACTIntroduction. Old ages are associated with physiologic deteriorations of all organs and tissues, such as involution of thymus and decreased function of gastrointestinal tract which lead to malnutrition. Involution of thymus will caused reduction of T cell subset for instance T cell CD4+. Prevalence of nutrient deficiency in old age was high, according to a survey that 35% of subjects with age above 50 years old showed deficiency for one or more vitamins and trace-elements. Zinc as one of trace-elements has vital role for immune system.Aim. Aims of this study are to know the mean of zinc serum level, proportions of zinc deficiency in elderly and correlation between zinc and CD4+ count.Methods and Subjects. Design of this study is cross sectional,  with study subjects including healthy elderly women from Aisyiah elderly club at Kota Gede Yogyakarta. Elderly who were eligible with study criteria were measured height, weight, zinc serum level, and CD4+ count. Correlation test was performed to know correlation between ages, weight, body mass index (BMI), and zinc serum level with CD4+ count. Significant variables will be tested with multiple linier regressions. Level of significance is p < 0.05.Results. A total healthy elderly women subjects were 60 persons with median of age 63.5 years old. Median zinc serum level was 5.47 umol/L with range between 3.25-             7.95 umol/L. Zinc deficiency (zinc serum level < 7.65 umol/L) occured in 95% of subjects. Mean of CD4+ count was 767.22±232.95 count/mm3. There were correlations between age, weight, and zinc serum level with CD4+ count (r= -0.296; 0.345; 0.324; 0.792, respectively). Results from linear regression model showed zinc serum level was the only variable that affect to CD4+ count (adjusted R2 = 0.622).Conclusion. Ninety five percent of healthy elderly women at elderly club Aisyiah Kota Gede Yogyakarta suffer from zinc deficiencies, and there is strong correlation between zinc serum level and CD4+ count. Keyword: zinc serum, CD4+ count, elderly
Ability of Curcuminoid from Curcuma domestica Val. in Reducing the Secretion of Reactive Oxygen Intermediates by Synovial Fluid Monocytes in Patients with Osteoarthritis Kertia, Nyoman; Asdie, Ahmad Husain; Rochmah, Wasilah; -, Marsetyawan
Indonesian Journal of Biotechnology Vol 16, No 2 (2011)
Publisher : Universitas Gadjah Mada

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AbstractIncreasing the secretion of reactive oxygen intermediates (ROI) by monocytes in the synovial fluid is anindicator to determine the severity of joint inflammation. Previous studies have shown that curcumin inhibitthe osteoarthritis progression with its ability to inhibite the activity of the nitric oxide synthase (NOS) enzymefrom macrophages. In this prospective randomized open end blinded evaluations = PROBE study, 80 patientswith knee osteoarthritis were eligable. The subject were devided in to two group: group who received 3 x 30mg of curcuminoid from Curcuma domestica Val. extract (curcuminoid group) and group who received 3 x 25mg of diclofenac sodium (diclofenac group) as comparison. The treatment was for 4 weeks time. The secretionof ROI by sinovial fluid monocytes was calculated by scoring the amount of formazan formation after neutralred staining in nitrobleu tetrazolium reduction assay. The result of this study showed that the secretion of ROIby synovial fluid monocytes was significantly decreased in both groups (p <0.001) respectively. There wasno significant difference in decreasing of ROI secretion of synovial fluid monocytes between both treatmentgroups (p = 0.92).Keywords : curcuminoid, diclofenac sodium, reactive oxygen intermediates, monocyte, osteoarthritis
Anthropometric Prediction Equations for Estimating Muscle Mass of Elderly Women Handayani, Maria Dara Novi; Sadewa, Ahmad Hamim; Farmawati, Arta; Rochmah, Wasilah
KEMAS: Jurnal Kesehatan Masyarakat Vol 14, No 2 (2018)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v14i2.14073

Abstract

Muscle Mass (MM) has an important role in health and physical performance. There are many MM prediction equations, but none is formulated in Indonesia. This study aimed to develop Anthropometric Equations (AE) prediction for MM. A cross sectional study was used to formulate AE prediction through multiple regression analysis.  The significance of observed differences between predicted and actual MM was tested by t test while level of agreement was assessed by Bland Altman plot. A significant correlation was found between MM and height, body mass index, calf/arm/waist circumferences, and waist hip ratio (p<0.05).  Regression anal¬ysis indicated that age, height, and Mid Arm Circumference (MAC) contributed significantly to MM. The resulting equation was MM (kg) = -10.22+(-.097x age)+(0.16xheight)+(0.30xMAC). There was no significant difference between actual and predicted MM results, and both had significant correlation. These results suggest that age, AP related to MM and AE provide valid prediction of MM for healthy elderly women in Jakarta.
HUBUNGAN KADAR GULA DARAH SAAT MASUK RUMAH SAKIT DENGANCARDIAC EVENTS PADA PENDERITA INFARK MIOKARD AKUT DI RS DR SARDJITO YOGYAKARTA Irawan, Bambang; Suharno, Suharno; Rochmah, Wasilah
Jurnal Kedokteran Brawijaya Vol 21, No 1 (2005)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.196 KB) | DOI: 10.21776/ub.jkb.2005.021.01.7

Abstract

Hyperglycaemia is common in patients with acute myocardial infarction with and without diabetes mellitus. There is a positive relationship between hyperglycaemia at thetime of event and highly incidence of mortality and morbidity after acute myocardial infarction. Consequently, understanding the possible mechanisms through which hyperglycaemia worsens the prognosis of acute myocardial infarction, as well as effectiveness of its control during acute myocardial infarction, seems to be a great relevance. This study to investigate wether a relationship exists between blood glucose level on admission and cardiac events in non diabetic patients after an acute myocardial infarction. Method,  a cohort prospective observational study was done on acute myocardial infarction’s patients who were hospitalized in ICCU DR Sardjito’s hospital from March 2002 until October 2004. Subject who met inclusion and exclusion criteria were divided into 2 groups, the group in which blood glucose level onadmission was ≤ 140 mg/dl and the group with bloodglucose on admission was > 140 mg/dl. Cardiac events as well as mortality, cardiac failure, reinfarction and cardiogenic shock were observed for 6 months. There were 95 subjects, 93 males and 2 females.
Effects of Multilevel Intervention in Workplace Health Promotion on Workers’ Metabolic Syndrome Components Zahtamal, Zahtamal; Rochmah, Wasilah; Prabandari, Yayi Suryo
Kesmas Vol. 11, No. 4
Publisher : UI Scholars Hub

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Sekitar 10-30% orang Asia dewasa mengalami sindrom metabolik. Penelitian ini bertujuan untuk mengungkap efek Promosi Kesehatan di Tempat Kerja PKDTK dengan intervensi multilevel pada komponen/penanda pekerja yang menderita sindrom metabolik. Penelitian ini dilakukan pada tahun 2014-2015 dengan menggunakan desain quasi experimental dengan intervensi subjek secara multilevel di Indonesia. Program PKDTK untuk kelompok intervensi multilevel berupa kombinasi latihan fisik, diet, pendidikan kesehatan, dukungan sosial, dan advokasi salama 12 minggu. Program PKDTK untuk kelompok kontrol hanya pendidikan kesehatan. Instrumen penelitian seperti IPAQ, table food recall 24 jam, alat pengukuran fisik, dan laboratorium klinis. Analisis data menggunakan Marginal Homogeneity, paired sample t, Mc Nemar, dan uji Wilcoxon. Intervensi PKDTK multilevel dapat meningkatkan aktivitas fisik dan asupan makanan yang sesuai dengan diet sindrom metabolik, khususnya untuk meningkatkan jumlah serat pangan dan pengurangan asupan kolesterol. Komponen sindrom metabolik yang membaik karena pengaruh PKDTK secara multilevel adalah tekanan darah sistolik dan diastolik, serta kadar glukosa darah puasa (nilai p < 0,05). Secara keseluruhan, intervensi PKDTK multilevel efektif untuk pengelolaan komponen sindroma metabolik pada pekerja. Approximately 10–30% of adult Asian people had metabolic syndrome. This study aimed to reveal effects of workplace health promotion (WHP) with multilevel interventions on workers’ metabolic syndrome component. This study was conducted in 2014-2015 using quasi-experimental design with multilevel subject intervention in Indonesia. The WHP program for multilevel intervention group included 12 weeks of combined physical training, diet, health education, social support, and advocacy. The WHP program for control group included only health education. Instruments used included IPAQ, table of 24-hour food recall, physical measurement tools, and clinical laboratories. Data analysis used Marginal Homogeneity, paired sample t-test, Mc Nemar, and Wilcoxon test. WHP multilevel intervention could improve physical activity and the nutrition in accordance with diet of workers, in particular to increase the amount of fiber and a reduce cholesterol intake. The improved metabolic syndrome components due to the influence of multilevel WHP were systolic and diastolic blood pressure, and fasting blood glucose levels (p value < 0.05). Overall, workplace health promotion multilevel interventions are effective for the management of metabolic syndrome components.
Co-Authors A.A. Ketut Agung Cahyawan W Ahmad Hamim Sadewa Ahmad Husain Asdie Ali Djamhuri Arta Farmawati Catur Saptaning Wilujeng Joedo Prihartono Lutfan Lazuardi Maria Dara Novi Handayani, Maria Dara Novi Marsetyawan -, Marsetyawan Marsetyawan Marsetyawan Nafrialdi Nafrialdi Niko Adhi Husni Nyoman Kertia Pradana Soewondo Purwita Wijaya Laksmi Resna, Riksa Wibawa Siti Setiati Sri Werdati, Sri Suhardi Darmo Atmodjo Susetyowati Tirza Z Tamin Yayi Suryo Prabandari Zahtamal Zahtamal