Syaflida, Rahmi
Departement Of Oral And Maxillofacial Surgery, Faculty Of Dentistry, Universitas Sumatera Utara, Medan, Indonesia

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Effectiveness of green tea on decreasing the patient’s blood pressure and pulse rate patient before dental extraction Ahyar Riza; Rahmi Syaflida; Indra B. Siregar; Ayu R. Nabila
Journal of Dentomaxillofacial Science Article In Press
Publisher : DiscoverSys Inc.

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Abstract

Objective: To determine the effectiveness of green tea on reducing patient’s blood pressure and pulse rate before dental extraction in the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Universitas Sumatera Utara. Material and Methods: This was an experimental quasi study with non-randomized pretest-posttest control group design. Purposive technique was used to select the subjects. The subjects were divided into 2 sample groups, each group consists of 18 patients. The control group were given warm water to drink before the dental extraction while the case group were given steeping green tea before the dental extraction. Blood pressure and pulse rate of each subjects were measured right after informed consent was given. The control group subjects were given to drink warm water while the case group subjects were given green tea steeping after the measurement of blood pressure and pulse rate. After 30 minutes, the blood pressure and pulse rate of each subjects were measured. Data obtained was statistically analyzed using Mann Whitney test and Wilcoxon test. Results: Blood pressure of pulse rate of the case group showed significant differences compared to the control group with a value of p = 0.000 <0.05. Conclusion: Steeping green tea was effective on reducing blood pressure and pulse rate in patients before tooth extraction.
Daya Antibakteri Streptococcus Mutans Menggunakan Ekstrak Daun Pegagan (Centella asiatica (l.) urban) Rahmi Syaflida; Ahyar Riza; Hendry Rusdy; Sukri Paramita Hasibuan
MAHESA : Malahayati Health Student Journal Vol 3, No 12 (2023): Volume 3 Nomor 12 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v3i12.12457

Abstract

ABSTRACT Oral health is very important in human life, to protect it preventive measures and medication must be taken to avoid the risk of infection. Streptococcus mutans is a caries-causing bacteria which can lead to odontogenic infections. Pegagan Centella asiatica (L.) Urban plant is a plant that has various properties, including as an antibacterial, because pegagan contains various active compounds such as triterpenoid, saponin, alkaloid and tannin. This study aims to prove the effectiveness of Centella asiatica (L.) Urban as antimicrobial to Streptococcus mutans. This study was a laboratory experimental study with a research design that is post test only control group design. Kirby bauer diffusion methode was used in this study with the bacteria samples used were Streptococcus mutans bacteria and used pegagan extract (Centella asiatica (L.) Urban) with several concentrations, namely 5%, 10%, 20%, 40% and negative control, namely DMSO. In this study, bacterial samples were cultured on nutrient media so that they were incubated for 24 hours and the inhibition zone formed was calculated using a caliper. The results of the research data were analyzed using the oneway Anova test and the Post Hoc LSD test. The results showed a significant difference in the diameter of the inhibition zone between 5%, 10%, 20%, 40% and negative control (p = 0.000 <0.05). In this study it can be concluded that pegagan extract (Centella asiatica (L.) Urban) is effective in inhibiting the growth of Streptococcus mutans at concentrations of 5%, 10%, 20% and 40% with the most effective concentration is 40%. Keywords: Centella Asiatica  (L.) Urban, Odontogenic Infections, Streptococcus Mutans  ABSTRAK Kesehatan gigi dan mulut sangat penting dalam kehidupan manusia, jadi untuk menjaganya harus dilakukan tindakan pencegahan dan pengobatan untuk menghindari resiko terjadinya infeksi. Streptococcus mutans merupakan bakteri penyebab karies yang dapat berlanjut menjadi menjadi infeksi odontogenik. Tumbuhan pegagan (Centella asiatica (L.) Urban) merupakan tumbuhan yang memiliki bermacam khasiat diantaranya yaitu sebagai antibakteri. Dikarenakan pegagan mengandung berbagai senyawa aktif seperti triterpenoid, saponin, alkaloid dan tanin. Penelitian ini bertujuan untuk membuktikan daya hambat ektrak Centella asiatica (L.) Urban terhadap pertumbuhan Streptococcus mutans. Penelitian ini merupakan penelitian eksperimental laboratorium dengan rancangan penelitian yaitu post test only control group design. Teknik difusi Kirby Bauer digunakan dalam penelitian ini dengan sampel bakteri Streptococcus mutans dan menggunakan ekstrak Centella asiatica (L.) Urban dengan beberapa konsentrasi yaitu 5%, 10%, 20%, 40% dan kontrol negatif yaitu DMSO. Pada penelitian ini sampel bakteri dibiakkan pada media nutrient agar kemudian diinkubasikan selama 24 jam dan dihitung zona hambat yang terbentuk menggunakan jangka sorong. Hasil data penelitian dianalisis dengan menggunakan uji oneway Anova dan uji posthoc LSD. Hasil penelitian menunjukkan perbedaan diameter zona hambat secara signifikan antara 5%, 10%, 20%, 40% dan kontrol negatif (p =0,000<0,05). Penelitian menyimpulkan bahwa ekstrak daun pegagan (Centella asiatica (L.) Urban) efektif dalam menghambat pertumbuhan bakteri Streptococcus mutans pada konsentrasi 5%, 10%, 20% dan 40% dengan konsentarsi paling efektif adalah 40%. Kata Kunci: Centella Asiatica  (L.) Urban; Infeksi Odontogenik; Streptococcus Mutans
Knowledge of pregnant women about risk factor of cleft lip and palate at Puskesmas Mutiara, Asahan, Indonesia Rusdy, Hendry; Syaflida, Rahmi; Hanafiah, Olivia Avriyanti; Ratnaningtyas, Jemima
Majalah Kedokteran Gigi Indonesia Vol 8, No 3 (2022): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.71456

Abstract

Cleft is a congenital abnormal space or gap in the upper lip, alveolus, or palate. This congenital abnormality occurs between the 5th and 10th weeks of pregnancy. Clefts are divided into cleft lip, cleft palate, as well as cleft lip and palate. Cleft lip and palate are caused by the interaction of individual genes with certain environmental factors. Mothers’ knowledge about risk factor of cleft lip and palate may promote better health-related behavior in their pregnancy by increasing the understanding about the risk factor. Unfortunately, until now there is still limited data about this. The purpose of this study was to determine the knowledge of pregnant women about risk factor of cleft lip and palate. This was a descriptive study that used the survey method. This study was conducted using a questionnaire distributed to 67 pregnant women (n = 67). The questionnaire consisted of 13 validated questions. The results of this study found that 10.4% of the respondents had good knowledge, 32.8% of the respondents had moderate knowledge and 56.7% of the respondents had poor knowledge. The overall knowledge of the pregnant women about risk factor of cleft lip and palate at Puskesmas Mutiara Asahan fell in the low category.
Influence of Theobroma cacao L on the adhesion of Streptococcus mutans Rahmi Syaflida; Gostry Aldica Dohude; Isnandar Isnandar; Risa Sepriyani
Journal of Syiah Kuala Dentistry Society Vol 8, No 2 (2023): December 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i2.29878

Abstract

Background: Indonesia is a tropical country with various plants ranging from forest products to agriculture and plantations. One of the plants with a lot of beneficial potential as a traditional medicine is the cacao plant (Theobroma cacao L.). Cocoa beans have a high content of polyphenol compounds, which significantly contribute as antioxidants, anti-cancer, anti-diabetes, anti-hypertension, and anti-inflammation. Ketekin, flavonoids, and tannins are compounds in cocoa beans known to have antimicrobial properties. Objective: This study aimed to determine the effectiveness of the antimicrobial power of cocoa bean extract in inhibiting the growth of Streptococcus mutans bacteria. Methods: This research is an experimental laboratory research. The study began with the manufacture of cocoa bean extract made into five concentrations, namely 50%, 25%, 12.5%, 6.25%, and 3.125%. This research was conducted by measuring the diameter of the inhibition zone through the Kirby-Bauer disk diffusion method using chlorhexidine 0.2% positive control and DMSO negative control. Results: The results showed at the largest concentration of 50%, the average value of the inhibitory zone obtained was 19.10 0.25 mm, and the smallest concentration of 3.12% was 7.25 0.29 mm. Conclusion: The study concludes that Cocoa bean extract effectively inhibits the growth of Streptococcus mutans.
Uji efektivitas ekstrak kulit jengkol (Pithecellobium lobatum benth.) terhadap pertumbuhan Streptococcus viridans: studi eksperimental laboratoris Syaflida, Rahmi; Ramayani, Al Shella; Isnandar, Isnandar; Riza, Ahyar
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 36, No 3 (2024): Desember 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v36i3.57875

Abstract

Pendahuluan: Kulit jengkol (Pithecellobium lobatum Benth.) merupakan limbah organik yang melimpah di pasar tradisional namun belum dimanfaatkan secara optimal. Kulit jengkol mengandung senyawa aktif seperti alkaloid, flavonoid, glikosida, steroid antrakinon, tanin, saponin, dan asam fenolat yang diketahui memiliki potensi antibakteri. Senyawa-senyawa ini dapat menghambat pertumbuhan bakteri dengan merusak struktur peptidoglikan pada dinding sel sehingga integritas sel terganggu. Penelitian ini bertujuan untuk menganalisis aktivitas antibakteri ekstrak kulit jengkol terhadap Streptococcus viridans secara in vitro. Metode: Penelitian eksperimental ini menggunakan rancangan post-test only control group design. Ekstraksi kulit jengkol dilakukan dengan metode maserasi, kemudian dilarutkan dalam DMSO menjadi lima konsentrasi (5%, 10%, 20%, 40%, 80%). Chlorhexidine gluconate 0,2% digunakan sebagai kontrol positif, sedangkan DMSO sebagai kontrol negatif. Uji antibakteri dilakukan dengan metode difusi cakram Kirby-Bauer pada media MHA dengan empat kali pengulangan. Analisis data dilakukan menggunakan SPSS versi 29 dengan uji normalitas Shapiro-Wilk, homogenitas Levene test, dilanjutkan ANOVA dan Post Hoc LSD. Hasil: Rata-rata diameter zona hambat meningkat seiring konsentrasi: 5% (7,325 mm), 10% (9,550 mm), 20% (10,400 mm), 40% (11,800 mm), dan 80% (14,775 mm). Terdapat perbedaan signifikan antar kelompok (p=0,001), kecuali antara konsentrasi 10%-20%, 20%-40%, dan 80% dengan kontrol positif (p>0,05). Simpulan: Ekstrak kulit jengkol efektif menghambat pertumbuhan Streptococcus viridans secara in vitro.Effectiveness test of jengkol peel extract (Pithecellobium lobatum benth.) against Streptococcus viridans growth: a laboratory experimental studyIntroduction: Jengkol peel (Pithecellobium lobatum Benth.) is an abundant organic waste often discarded in traditional markets but remains underutilized. It contains active compounds such as alkaloids, flavonoids, glycosides, steroids, anthraquinones, tannins, saponins, and phenolic acids, many of which exhibit antibacterial potential. These compounds can inhibit bacterial growth by disrupting the peptidoglycan structure in the bacterial cell wall, thereby compromising cell integrity. This study aimed to analyze the antibacterial effectiveness of jengkol peel extract against Streptococcus viridans in vitro. Methods: This laboratory experimental study used a post-test-only control group design. Jengkol peel was extracted using the maceration method and dissolved in DMSO to obtain five concentrations (5%, 10%, 20%, 40%, and 80%). Chlorhexidine gluconate (0.2%) served as a positive control, and DMSO as a negative control. The antibacterial activity was evaluated using the Kirby-Bauer disc diffusion method on Mueller-Hinton agar (MHA), with four replicates per treatment. Data were analyzed using SPSS version 29 with Shapiro-Wilk test for normality, Levene’s test for homogeneity, followed by one-way ANOVA and post hoc LSD tests. Results: The mean inhibition zone diameters increased with higher concentrations: 5% (7.325 mm), 10% (9.550 mm), 20% (10.400 mm), 40% (11.800 mm), and 80% (14.775 mm). Significant differences were observed among treatment groups (p=0.001), except between 10%-20%, 20%-40%, or 80% and the positive control (p>0.05). Conclusion: Jengkol peel extract demonstrates antibacterial activity against Streptococcus viridans in vitro.