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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Syntax Literate: Jurnal Ilmiah Indonesia JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmiah Farmasi Farmasyifa Borneo Journal Of Pharmascientech Jurnal Pengabdian Masyarakat Indonesia Jurnal Impresi Indonesia Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Jurnal Pengabdian Masyarakat Dharma Andalas Jurnal Sains dan Kesehatan JFKI
Rosiana Rizal
1Program Studi FarmasiUniversitas Dharma Andalas
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FORMULASI CANGKANG KAPSUL DARI PEKTIN KULIT BUAH NANGKA (Artocarpus heterophyllus Lam) DAN UJI WAKTU HANCUR KAPSUL Rosiana Rizal; Salman Salman; Eka Wulandari
Jurnal Ilmiah Farmasi Farmasyifa Vol 6, No 2 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiff.v6i2.11933

Abstract

Capsule is capsule preparations which consisting of a drug in a soft capsule and hard capsule sell. Capsule is the preparations that most people used to discover the unpleasant taste of the drug. Most of capsule sell are made of gelatin, but it can also made with starch or other ingredients. The other ingredients which can substitute gelatin is pectin. Pectin is an ingredient belong to the class of carbohydrates. This study aim to find others alternative that can be used as new ingredients of capsule sell, which is jack fruit peels. Dissolved 20 mg jack fruit peels in 1000 ml of distilled water and, added 5% of citric acid. Then extracted on a hot plate with a stirring speed 600 rpm, temperature of 85ͦC, for 120 minutes. The yield obtained was 0.319%. The best formulations results were 2 (0.7 gram pectin, 5.00 gram carrageenan, 100ml disttiled water). The result of the evaluation of capsule sell standards with a body diameter of 6,2 mm, 6,3 mm, of a lid diameter, a body length of 15,2 mm, a lid length of 07.8 mm, and those that are unqualified with 0.09 gram of capsule weights. The organleptic results are light brown color, texture a little loud and there is no fragrance. The capsule sell disintegration should meet the requirements set by the Indonesian Pharmacopoeia V edition, is 13 minutes 47 seconds.Keywords: jackfruit skin (Artocarpus heterophyllus Lam), pectin, capsule shell
Pengaruh Pemberian Ekstrak Etanol Daun Sisik Naga (Pyrrosia Piloselloides L.) terhadap Penurunan Kadar Kolesterol Total Mencit Hiperkolesterolemia: Effect of Dragon Scales Leaf Ethanol Extract (Pyrrosia Piloselloides L.) on Reducing Total Cholesterol Levels in Hypercholesterolemic Mice Helmice Afriyeni; Nesya Indah Putri; Rosiana Rizal
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1582

Abstract

Hypercholesterolemia is one of the risk factor for cardiovascular disease such as stroke, atherosclerosis and coronary heart disease. The purpose of this study was to determine the effect of ethanol extract of dragon scales leaves (Pyrrosia piloselloides L.) on reducing total cholesterol (TC) of test animals. The instrument to test was 25 male white mice were induced hypercholesterolemia by eating a high fat diet (MDLT) in around 14 days. The animals were declared as hypercholesterolemia if the total of cholesterol level (TC) more than 230 mg/dl. Then the Animals divided into five groups namely positive control, comparison (simvastatin), and the group given the test extract doses of 25, 50, 100 mg/kgBB. The treatment was given for 15 days, and TC level were checked on days 0, 5, 10 and 15. The data were analyzed by Two Way of ANOVA and continued with Duncan's test. The results showed that the dose of the tested extract and the duration of administration had a significant effect (p
Profil Flavonoid Total Ekstrak Etil Asetat Bunga Senna alata (L.) Roxb. Berdasarkan Analisis Spektrofotometri UV–Vis Rosiana Rizal; Rustini; Murandi Kesuma
Jurnal Farmasi dan Kesehatan Indonesia Vol. 1 No. 2 (2026): Desember 2025- Februari 2026
Publisher : Samudra Ilmu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Flavonoid merupakan senyawa fenolik yang paling banyak ditemukan pada tanaman. flavonoid dapat melindungi tanaman dari sinar uv serta sebagai pigmen warna pada tanaman. Berdasarkan B, BPOM daun ketepeng cina mengandung flavonoid. Penelitian ini bertujuan untuk mengetahui adanya senyawa flavonoid serta kadar flavonoid total pada ekstrak etil asetat bunga ketepeng cina. Bunga ketepeng cina diekstraksi dengan metode maserasi menggunakan pelarut etil asetat. Uji kualitatif flavonoid menggunakan metode sianidin test dan uji kuantitatif kadar flavonoid total menggunakan spektrofotometri uv-vis. Bunga ketepeng cina sebanyak 150 gram diekstraksi 3 liter etil asetat didapatkan ekstrak kental sebesar 15,6074 gram. Hasil penelitian diperoleh bahwa ekstrak bunga ketepeng cina bewarna kuning kecoklatan, kadarair sebanyak 6,03% dan kadar abu 4,01% . Hasil uji kualitatif menggunakan metoda sianidin tes didapatkan hasil positif dengan perubahan warna menjadi kuning kehitaman. Hasil uji kuantitatif dengan panjang gelombang 437 nm diperoleh kadar flavonoid total pada bunga ketepeng cina sebesar 35,557 mg QE/g atau 3,5557 %.
Standarisasi Ekstrak Daun Jambu Air sebagai Bahan Baku Obat Herbal Terstandar pada Pengobatan Hipertensi Rosiana Rizal
Jurnal Impresi Indonesia Vol. 5 No. 5 (2026): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v5i5.7819

Abstract

Penelitian eksperimental dilakukan untuk menguji mutu daun jambu air sebagai bahan baku obat tradisional, baik dalam kategori obat herbal terstandar maupun fitofarmaka, sesuai standar Farmakope Herbal Indonesia. Tujuan penelitian ini adalah untuk mengevaluasi mutu ekstrak kental daun jambu air sebagai bahan baku obat herbal terstandar sesuai dengan persyaratan Farmakope Herbal Indonesia Edisi II. Kandungan rutin di dalamnya berperan sebagai diuretik yang menghambat penyerapan kembali ion natrium di tubulus ginjal, memicu vasodilatasi untuk memperbaiki aliran darah, serta memberikan efek antioksidan guna meningkatkan perfusi glomerulus dalam penanganan hipertensi. Berdasarkan hasil penelitian, bahan uji telah memenuhi kriteria mutu menurut Farmakope Herbal Indonesia yang mencakup aspek fisikokimia seperti rendemen, kadar air, abu, dan bobot jenis. Pengujian keamanan yang meliputi residu logam dan kontaminasi mikroba juga berada dalam batas normal. Hasil ini juga didukung oleh pemenuhan ambang batas aman untuk cemaran logam dan mikroba, konsistensi kadar flavonoid dan antioksidan, serta adanya aktivitas diuretik yang terukur secara ilmiah. Dapat disimpulkan bahwa ekstrak kental daun jambu air memenuhi spesifikasi Farmakope Herbal Indonesia sebagai bahan baku obat herbal. Kandungan senyawa aktif berupa flavonoid, saponin, tanin, dan triterpenoid di dalamnya berperan dalam mengatasi hipertensi, di mana aktivitas diuretik sebesar 93,33 persen berhasil ditunjukkan pada dosis 400 mg/kgBB tikus.
Co-Authors Afriyani Armenia, Armenia Dwisari Dillasamola Eka Wulandari Helmice Afriyeni Islahuddin Islahuddin Kamal, Sefrianita Laras Alhabil Lusia Eka Putri M. Rifqi Efendi Mei Nissar Yulas Tari Mei Nissar Yulas Tari Mesa Sukmadani Rusdi Mike Esfika Murandi Kesuma Muslim Suardi Nesya Indah Putri Nofrizal Nurunnisa Aprilya Yulfi Rustini Rustini Rustini Salman - Sara Surya Sara Surya Sara Surya Sefrianita Kamal Widia Rahma Putri Yulihasri