Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal MOSIRAHA : Jurnal Pengabdian Farmasi Borneo Journal of Pharmacy
Muhammad Ilyas Yusuf
Universitas Halu Oleo
Humanities Health Professions Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Level of Cytokine Interleukin-6 and Interleukin 1-β on Infectious Rat Model Treated with Etlingera elatior (Jack) R.M. Smith Fruit Extract as Immunomodulator Adryan Fristiohady; Wahyuni Wahyuni; Fadhliyah Malik; Muhammad Ilyas Yusuf; Wa Ode Salma; Rini Hamsidi; Fredy Talebong; Yuliansyah Yuliansyah; La Ode Muhammad Julian Purnama; Saripuddin Saripuddin; Sahidin Sahidin
Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i2.1318

Abstract

Etlingera elatior (Jack) R.M Smith or locally in Southeast Sulawesi known as Wualae fruit has activity as an immunomodulator by increasing phagocytosis activity. Prior studies have been conducted to observe the effect of E. elatior as an immunomodulator, thus further study is needed to observe the production of cytokines such as IL-1β and IL-6 which are responsible for the immune responses. Etlingera elatior fruit macerated with 96% ethanol for three days and produced a total of ±74.6 g concentrated extract. Experimental animals used were divided into four groups (n=4) and treated orally once a day for seven days as follows: group I (0.5% Na CMC); group II (Stimuno®); group III (E. elatior fruit extract dose of 300 mg/kg BW); and group IV (E. elatior fruit extract dose of 400 mg/kg BW). On the eight-day, animals were infected with Staphylococcus aureus intraperitoneally and left for an hour. Thereafter, blood was collected and assayed using ELISA Kit (Elabscience rat IL-1β and Elabscience rat IL-6). Results demonstrated that group IV increased levels of IL-1β and group III and IV increased level of IL-6 (p<0.05). Increased levels of IL-1β and IL-6 are associated with phagocytosis in the immune response. In conclusion, E. elatior fruit extract at doses of 300 and 400 mg/kg BW increases levels of IL-1β and IL-6.
PEMANFAATAN SUMBER DAYA ALAM SEKITAR DALAM UPAYA PENANGGULANGAN STUNTING DI DESA SOROPIA KECAMATAN SOROPIA Irnawati; Mesi Leorita; Ruslin; Muhammad Ilyas Yusuf; Sunandar Ihsan
Mosiraha: Jurnal Pengabdian Farmasi Vol. 2 No. 1 (2024): Edisi April 2024
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/mosiraha.v1i3.11

Abstract

Stunting pada anak-anak merupakan salah satu masalah kesehatan masyarakat yang utama di Indonesia. Stunting menjadi masalah yang sangat serius karena mempengaruhi kualitas sumber daya manusia di masa mendatang. Oleh karena itu, penting adanya promosi kesehatan untuk meningkatkan kesadaran masyarakat tentang bahaya stunting. Kegiatan ini bertujuan untuk memberikan pemahaman kepada masyarakat desa Soropia tentang bahaya stunting. Metode yang digunakan pada kegiatan ini yaitu penyuluhan atau ceramah. Hasil kegiatan pengabdian ini terlihat antusias masyarakat Desa Soropia untuk mengikuti/menerima informasi yang disampaikan tentang bahaya stunting. Hasil diperoleh dari sosialisasi ini yaitu masyarakat dapat memahami materi tentang bahaya stunting yang dibuktikan dengan peningkatan pengetahuan setelah sosialisasi dan pemahaman masyarakat Soropia mengenai bahaya stunting dan pentingnya mencegah stunting sejak masa kehamilan
Co-Authors Adryan Fristiohady Fadhliyah Malik Fredy Talebong Irnawati La Ode Muhammad Julian Purnama Mesi Leorita Rini Hamsidi Ruslin Sahidin Sahidin Saripuddin Saripuddin Sunandar Ihsan Wa Ode Salma Wahyuni Wahyuni Yuliansyah Yuliansyah