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All Journal Jurnal Perikanan dan Kelautan Berkala Perikanan Terubuk Jurnal Online Mahasiswa (JOM) Bidang Perikanan dan Ilmu Kelautan JURNAL PENGABDIAN KEPADA MASYARAKAT Acta Aquatica: Aquatic Sciences Journal Marinade Authentic Research of Global Fisheries Application Journal (Aurelia Journal) Asian Journal of Aquatic Sciences
N. Ira Sari
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Agriculture, Biological Sciences & Forestry Arts Humanities Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Social Sciences Other

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ANTIBACTERIAL ACTIVITY OF HYDROXYAPATITE FROM FRESHWATER MUSSEL SHELL (Pilsbryochoncha sp.) AGAINST Streptococcus mutants BACTERIA Sidauruk, Santhy Wisuda; Rusdi, Rizky Ramadhan; Sari, N. Ira
Aurelia Journal Vol 6, No 2 (2024): October
Publisher : Politeknik Kelautan dan Perikanan Dumai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/aj.v6i2.13519

Abstract

Unutilized mussel shells have the potential to become solid waste and potentially pollute the environment. In fact, the shell has a high calcium content of 61.39% which can be used as a precursor to hydroxyapatite. Hydroxyapatite is known to have antibacterial activity that causes dental caries, namely Streptococcus mutants. However, the antibacterial activity of HAp from mussel shells against S. mutans bacteria is not yet known. This study aims to determine the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and determine the inhibition zone against S. mutants bacteria from hydroxyapatite of mussel shells. This research procedure started from hydroxyapatite synthesis, MIC test, MBC test, and inhibition zone analysis at several HAp concentrations, namely 12.5 mg/mL, 25 mg/mL, and 50 mg/mL, as well as positive control and negative control. The results showed that no KHM and KBM values were found at the HAp concentrations used. Furthermore, the diameter of the hydroxyapatite inhibition zone against S. mutants bacteria at concentrations of 12.5 mg/mL, 25 mg/mL, and 50 mg/mL, was 0 mm. Thus, the hydroxyapatite of mussel shells is neither bacteriostatic nor bacteriocidal.
Co-Authors ', Desmelati ', Febriandi ', Firmansyah ', Megawati ', Purwanda ', Suparmi AA Sudharmawan, AA Akmin Sulaiman Harahap Ambarita, Befrison Utama Andarini Diharmi Anggi Anggraini, Anggi Angraini, Yannisa Anisa Triwulandini Antonius Sihombing Armelia Rahmasari Beri Prima Panjaitan Bustari Hasan Candra Arjuna Coki Randi Natama, Coki Randi D P N Daeli, Jansen Danny Handoko Danny Handoko Deevrizal Deevrizal Deli Rosiana Yanti Denny Fajar Timotius Ginting Desi Damayanti Desi Lestari Desmelati Desmelati Desti Nurfiani Dewi Trisnawati Dewita Dewita Dian Destari Dian Iriani Dinda Futhi Khumaira Edison Edison Edison Edison Elga Nurul Adha fajrifa, Eldya novri Gaol, Anggi Julisna Lumban Herlima Yuli, Herlima Hoki Winda Lestari Hutabarat, M. Aziz Amin Hutabarat, Sarima Ruth Isnawati ' Jansen D P N Daeli Joslin Sirait Josua Naibaho, Josua Karnila, Rahman Karnila Legia Ayu Gustina M Lumbantobing, Julio Malindo, Robi Mardianto Hidayat Martahan Gabema S Mery Sukmiwati Mhd. Ridho Putra Monika Triana Muhammad Ridwan Muhammad Zaid Antoni, Muhammad Zaid Nur Irdawati Octavianus Samosir Pipit Pasaribu Pramana, Ilham Purnama Simamora Purnama Wirawan Rahayu, Rinaldi Fitra Rahmi, Fauziah Rangkuti, Ahmad Kamil Revi Susanti Rinaldi Panjaitan, Rinaldi Riski Abadi Ronaldo Siagian Roy Saputra Situmorang Rusdi, Rizky Ramadhan Santhy Wisuda Sidauruk Sidauruk, Muhammad Irfan Rusadi Santhy Silvia Isma Utari MZ Solo Oba Putra Sibagariang Sri Tika Evianty S Stella Puspaning Mawarni Suardi Loekman Sumarto ' Sumarto Sumarto Sumarto Sumarto Suparmi Suparmi Suyatno ' Syahrul ' Syahrul Syahrul Syaiful Irzal Tamba, Putri Geovany Teddi Seftiadi Azfan Tjipto Leksono Trisna Wiga Putri Vattaah, Atiqah Nurul Wahyu Oloan Sagala Wiwit Pusra, Wiwit Yefri Mufti Yuliati '