Claim Missing Document
Check
Articles

Found 13 Documents
Search

The Effect of Propylene Glycol and Menthol as Enhancers on the Physical Properties and Skin Irritation Index of Meloxicam Gel Falahi, Asa; Rohman, Anies
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 3 No. 2 (2025): Desember
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v3i2.41

Abstract

Abstract Background: The drawback of meloxicam when used orally is that it slows the onset time of meloxicam. Other side effects of oral use include gastrointestinal disorders, dyspepsia, nausea, diarrhea, upper gastrointestinal infections, abdominal pain, swelling, and bloating. These side effects have been reported in 15–20% of patients. There is a need to develop a transdermal meloxicam formulation with a modified penetration system. Purpose: This study aims to develop a formulation of meloxicam gel preparations with a direct release system towards the skin barrier and within a period of time is extended by using 10% propylene glycol and 3% menthol as an enhancer to get the optimum formula of meloxicam gel with good physical properties and does not irritate the skin. Methods: This research method is a laboratory experimental study. Gel preparations were made by varying the enhancer agents, namely propylene glycol and menthol. The gel preparations were made by developing the gelling agent to an optimal level. Other additional ingredients were mixed with various enhancer variations. Results: The observed physical properties of the gel included organoleptic characteristics, pH, viscosity, spreadability, and irritation tests. Overall, the test results showed data that met the applicable requirements. All four formulas showed significant differences in each test and did not show signs of skin irritation. Conclusions: The results show that variation concentration of enhancer has an effect to gel form, smell viscosity and spreadability but has no effect to gel colour and pH. All formulas show not irritate the skin.
BIJAK MENGGUNAKAN KOSMETIK DAN SUPLEMEN KESEHATAN Dewi, rashati; Falahi, Asa; Rohman Dwijayanti, anies; Christiningtyas Eryani, Mikhania
Jurnal SADEWA Vol 4 No 01 (2026): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/sadewa.v4i01.1096

Abstract

Teenagers are the next generation and the determining factor of the nation's future. The use of supplements and cosmetics is an important matter for teenagers to fulfill. The consumption of supplements by teenagers is a form of daily nutritional fulfillment activity. The use of cosmetics also attracts the attention of teenagers. The aim of this community service is to provide education on SMK Farmasi dr. Soebandi student to be wise in using cosmetics and health supplements. The method in this activity using explanation method and quantitative questionnaire data collection. This activity has a positive impact on increasing student knowledge also awareness of the importance of choosing and using cosmetics and supplements safely. That can be seen the increase pre-post test score from 63 to 80. Although the increase knowledge statistically is not significant, but this activity enhances participants understanding and encourages more rational consumer behavior.
Formulasi dan Evaluasi Sifat Fisik Sprue Patch Ekstrak Daun Bidara (Ziziphus mauritiana Lamk.) Aditama, Agnis Pondenika Ria; Ainurrohmah, Sofy; Rashati, Dewi; Falahi, Asa
Journal of Islamic Pharmacy Vol 10, No 2 (2025): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v10i2.33747

Abstract

Kesehatan rongga mulut sangat penting untuk menunjang aktivitas sehari-hari, mengingat gangguan seperti Recurrent Aphthous Stomatitis (RAS) atau sariawan dapat menghambat kualitas kinerja individu. Penelitian ini bertujuan untuk mengembangkan formula berbasis bahan alam menggunakan ekstrak etanol daun bidara (Ziziphus mauritiana Lamk.) yang diketahui memiliki aktivitas antimikroba dalam mengatasi sariawan. Evaluasi fisik terhadap tiga formulasi (F1, F2, F3) dilakukan melalui uji keseragaman bobot, ketebalan, pH, dan daya lipat. Hasil penelitian menunjukkan nilai keseragaman bobot berturut-turut adalah 0,028 g; 0,034 g; dan 0,05 g; ketebalan seluruh formula 0,1 mm; pH pada rentang 6,5; 5,96; dan 5,5; serta daya lipat sebesar 210, 207, dan 205. Hasil pengujian menunjukkan bahwa ketiga formulasi tersebut memenuhi persyaratan fisik sediaan patch.