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All Journal Pharmaciana: Jurnal Kefarmasian IDJP (Indonesian Journal of Pharmaceutics) Jurnal Pengabdian UNDIKMA Jurnal Ilmiah Farmasi Simplisia Jurnal Farmasi Galenika
Mikhania Christiningtyas Eryani
Bagian Farmasetika, Fakultas Farmasi Universitas Jember; Program Magister Farmasi, Fakultas Farmasi Universitas Jember
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The effect of concentration variation of ethanolic extract from potato peels (Solanum tuberosum L.) on the physical properties and antibacterial activity of gels against Propionibacterium acnes Rashati, Dewi; Eryani, Mikhania Cristiningtyas
Pharmaciana Vol. 8 No. 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v8i2.8395

Abstract

Gel is a semisolid dosage form that consumers prefer because of its cool sensation. This research aimed to identify the effect of different concentrations of ethanolic extract from potato peels on the physical properties and the antibacterial activities of the resultant gels against Propionibacterium acnes. The gel was prepared with three formulas using a variety of potato peel concentrations, namely 50%, 60% and 70%. Its physical properties were analyzed based on organoleptic observation, homogeneity, pH, and spreadability. The results showed that the ethanolic extract of potato peels affected the color and viscosity of the gel. However, no effects were detected on shape, smell, pH, and spreadability. All formulas showed strong inhibitory capacity against Propionibacterium acnes.
Lip Balm Formulation and Physical Properties Evaluation Of Yellow Pumpkin Fruit (Cucurbita Moschata Duchesne) Ethanol Extract with Cera Alba Variation Concentration Christiningtyas Eryani, Mikhania; Risky Ayu Paramita, Denok; Ayuning Trias, Diah; Husni, Patihul
Indonesian Journal of Pharmaceutics Vol 6, Issue 3, Sept - Dec 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v6i3.60617

Abstract

Lip balm is a cosmetic product generally used to care for, moisturize, decorate, and protect lips from environmental influences. This study aims to determine the effect of variations inconcentration of cera alba as base on the lip balm physical properties of yellow pumpkin fruit (Cucurbita moschata Duchesne)ethanol extract. The experimental design used was a pre-experimental one-shot case study. This study employed three formulas with varying concentrations of Cera alba, namely 10% (F1), 15% (F2), and 20% (F3). The physical properties of the lip balm under investigation included homogeneity, pH, adhesion, and hardness. The results showed that the variation concentration of cera alba had affect on adhesion and hardness, while not affect the homogeneity of physical properties and pH. Keywords : Yellow pumpkin, cera alba, lip balm
Pengaruh Variasi Konsentrasi Natrium Hidroksida (NaOH) Terhadap Sifat Fisik Sabun Padat Berbahan Minyak Goreng Bekas Pakai Mikhania Christiningtyas; Nur; Risky Ayu Paramita, Denok; Patihul; Riskha Nurmalasari, Dewi
JURNAL FARMASI GALENIKA Vol 12 No 1 (2025): Jurnal Farmasi Galenika
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i1.378

Abstract

Soap is a cleanser made by a chemical reaction between sodium or potassium and fatty acids from vegetable oils or animal fats. Used cooking oil can be used as the main ingredient for the oil component in making solid soap used for washing dishes. This research aims to determine the effect of variations in NaOH concentration on the physical properties of solid soap preparations made from used cooking oil. Preparations were made with NaOH concentrations between 5% (F1), 8.5% (F2) and 12% (F3). The physical property tests carried out are organoleptic tests including texture, color and odor, pH test, water content test and foam height test. Organoleptic data shows that F1 has a smooth texture, yellow color and a weak lemon smell. F2 has a slightly rough texture, yellow color and a weak lemon smell. F3 has a rough texture, yellow color and does not smell like lemon. F1 pH value is 10.36 ± 0.16; F2 was 10.52 ± 0.33; and F3 of 10.47 ± 0.18. The results of the water content test showed that F1 data was 0.91% ± 0.25; F2 was 0.88% ± 0.04; and F3 of 1.04% ± 0.20. The foam height test results showed that F1 data was 6.97 ± 1.00 cm, F2 was 6.57 ± 0.38 cm, and F3 was 5.83 ± 0.32 cm. The conclusion is that NaOH variations concentration have an effect on the texture and smell of soap but have no effect on color, pH, water content and height of soap foam.
Pengembangan Sediaan Gel Ekstrak Bonggol Pisang Ambon Husni, Patihul; Prayitno, Adi; Baitariza, Ardian; Christiningtyas Eryani, Mikhania; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 12 No 1 (2025): Jurnal Farmasi Galenika
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i1.382

Abstract

Ambonese banana (Musa paradisiaca var. Sapientum (L.)) has a tuber with several benefits including for wound-healing. The Ambonese banana tuber contains protein, fat, vitamins A and C. In addition, the tannins, flavonoids, and saponins contained in the sap of the Ambonese banana tuber are beneficial in wound healing. The purpose of this study was to obtain the best gel formula containing extract of Ambonese banana tuber based on physical evaluation. The study was conducted by making three different gel formulations (F1, F2, F3) containing 5% Ambonese banana tuber extract. Physical assessment of the gel preparation included organoleptic tests, pH determination, homogeneity, viscosity, and spreadability evaluation. The results showed that the preparation was in the form of a homogeneous gel with a reddish-brown color and a distinctive odor. The pH of the preparation was around 5-8 with a viscosity between 500-3500 cps and a spreadability of 5-8 cm. F2 is the best gel formula based on physical evaluation during four weeks of storage with a composition of 5% HPMC, 15% propylene glycol, 0.2% methylparaben, 5% Ambonese banana tuber extract, and 100% aquadest.
Edukasi Kesehatan Melalui Pelatihan Pembuatan Sabun dan Handsanitizer Ramah Lingkungan di Desa Subo Kabupaten Jember Mikhania Christiningtyas Eryani; Amaliyah Nurul Hidayah
Jurnal Pengabdian UNDIKMA Vol. 4 No. 4 (2023): November
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v4i4.8882

Abstract

This service activity aims to increase the knowledge and skill of young women in Subo Village in making soap and hand sanitizer made from natural, environmentally friendly materials. The method used in this activity was the method of counseling and product manufacturing training. The instrument for evaluating this service was a questionnaire, which was analyzed descriptively, qualitatively, and quantitatively. The results of this service showed that the participant's knowledge and skills increased. The data evidence this: the participant's score was 80.7 before and after the service was 86. So that the increase in the participant's score after the service was carried out was 5.3 or 6.6%. This increase occurred in aspects of the chemical content of klerak and the method of making soap and hand sanitizer.
Formulasi Formulasi dan Evaluasi Gel Ekstrak Daun Nangka (Artocarpus heterophyllus Lam.) dengan Gelling Agent CMC Na: Gel daun nangka eryani, MIKHANIA CHRISTININGTYAS ERYANI
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 4 No. 1 (2024): Juni 2024
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v4i1.559

Abstract

Hand sanitizer is a preparation in the form of a gel that is widely used by the public as a practical hand washing tool. Jackfruit leaves (Artocarpus heterophyllus Lam.) have antibacterial properties that can be used for hand sanitizers. This study aims to formulate and evaluate jackfruit leaf extract gel with CMC Na gelling agent at concentrations of 1% (F1), 2% (F2) and 3% (F3). Evaluation of physical properties carried out includes organoleptic tests, homogeneity, pH, spreadability and viscosity. The results showed that all formulas were brown, smelled of mint, and homogeneous. F1 was slightly thick, F2 was thick and F3 was very thick. The pH of F1, F2 and F3 were 5.8 ± 0.05; 5.9 ± 0.05, and 5.8 ± 0.1. The spreadability of F1, F2 and F3 were 6.6 ± 0.49 cm respectively; F2 6.4±0.30 cm and F3 5.5±0.15 cm. The viscosity of F1, F2 and F3 were 13.3±2.88 dPa.s; 25±0 dPa.s and 30±0 dPa.s respectively. Based on these results, it can be concluded that the variation of CMC Na concentration affects the organoleptic shape, spreadability and viscosity but does not affect the organoleptic odor and color, homogeneity and pH
Formulasi Dan Evaluasi Sediaan Gummy Candies Mengandung Infusa Daun Jambu Biji (Psidium guajava L.) Dengan Variasi Konsentrasi Sukrosa Christiningtyas Eryani, Mikhania; Judy Handojo, Kukuh; Safitri, Manzil; Husni, Patihul
JURNAL FARMASI GALENIKA Vol 11 No 3 (2024): Jurnal Farmasi Galenika Vol 11 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i3.347

Abstract

Guava leaves (Psidium guajava L.) are a traditional medicine used to treat diarrhea. The subtance contained in guava leaves that can have antidhiarrheal properties is tannin. Gummy candies are sweet product made from the main gel- forming ingredients such as gelatin, carrageenan, jelly, as well as sweetening ingredients such as sucrose, lactose, glukose, and others. This research aims to formulate and evaluate guava leave infused gummy candies with varying sucrose concentrations of 15 (F1)%, 20% (F2), and 25% (F3). Test data for the organoleptic physical properties of F1, F2, and F3 are chewy texture, weak melon aroma, green color, and sweet taste. In the weight uniformity test there was no difference between F1, F2, and F3. The average pH test results where F1 is 5.81, F2 is 6.16 and, F3 is 6.63. Testing the water content of gummy candies resulted in average of F1 is 12.4%, F2 is 27.5, and F3 is 43,29%. The conclusion is variation concentration of sucrose affect pH and water content but its not affect organoleptic and weight uniformity of gummy candies.
Pengembangan Bahan Farmasi: Pengaruh Variasi Suhu Pengeringan Terhadap Sifat Fisik Serbuk Kering Labu Siam Husni, Patihul; Tryani Sutisna Putri, Sussy; Erika Herawati, Irma; Christiningtyas Eryani, Mikhania
JURNAL FARMASI GALENIKA Vol 11 No 3 (2024): Jurnal Farmasi Galenika Vol 11 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i3.357

Abstract

Chayote (Sechium edule (Jacq). Swartz) is potential to be a pharmaceutical material.  Therefore, this study aimed to determine the effect of drying temperature variations on the physical properties of dry chayote powder. The temperatures used in the drying process are 100 ºC, 80 ºC, and 60 ºC. Evaluation of dry chayote powder includes organoleptic test, water content, flow time, angle of repose, compressibility index, and particle size distribution. The results showed brown powder in color with a distinctive aromatic odor and sweet taste, 2.50-2.80% of water content, 5-6 second in flow time showing good flow properties, 32.21-33.42 º in angle of repose showing powder easy to flow, and compressibility index of 10% -18%. The particle size distribution of dry chayote powder was fine powder with particle size around 0.5-0.7 mm. Statistical analysis results showed there were no significant effect of the drying temperature variations on the physical properties of dry chayote powder. The conclusion of this study is drying temperature variations (100 ºC, 80 ºC, dan 60 ºC) does not affect the physical properties of dry chayote powder.
Pemanfaatan Ekstrak Kulit Buah Naga (Hylocereus polyrhizus) Sebagai Bahan Aktif Pembuatan Sabun Cair Alami Januarti, Melinda; Husni, Patihul; Christiningtyas Eryani, Mikhania
JURNAL FARMASI GALENIKA Vol 11 No 3 (2024): Jurnal Farmasi Galenika Vol 11 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i3.358

Abstract

Nowadays, many people are paying attention to the benefits of natural soap because it is believed to be gentler on the skin and environmentally friendly. This research aims to determine the formulation of natural liquid soap with the addition of dragon fruit peel extract that is effective and meets the requirements. The method used is an experimental method by formulating a natural liquid soap containing 0.5% dragon fruit peel extract as the active ingredient and adding cocamid-DEA as a foam stabilizer in variations of 1%, 3%, and 5%. The tests conducted include organoleptic tests, pH tests, foam height tests, viscosity tests, and skin condition tests. Research shows that the natural liquid soap produced has characteristics of a reddish-purple color, a distinctive scent, and varying consistency depending on the concentration of cocamid-DEA added, where F3 has the highest viscosity at 528.9 mPa, F2 at 525.7 mPa, and F1 at 428.9 mPa. From the pH testing results, F1 has a pH of 8, while F2 and F3 have a pH of 9. In the foam height test, all formulas met the soap foam height requirement of 1.3-22 cm. The first formulation of natural liquid soap with the addition of dragon fruit peel extract as an active ingredient, based on organoleptic tests, pH tests, viscosity, and foam height tests, produced the best results and met the requirements.
Co-Authors Adi Prayitno Amaliyah Nurul Hidayah Ardian Baitariza, Ardian Ayuning Trias, Diah Denok Risky Ayu Paramita Erika Herawati, Irma Januarti, Melinda Judy Handojo, Kukuh Nur Patihul Patihul Husni Rashati, Dewi Riskha Nurmalasari, Dewi Safitri, Manzil Tryani Sutisna Putri, Sussy