Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Althea Medical Journal Journal of Maternal and Child Health
Budi Setiabudiawan
Department of Child Health Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung, Indonesia
Medicine & Pharmacology Public Health

Published : 16 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 16 Documents
Search

 1   2 
Perbedaan Kadar Platelet Activating Factor Plasma antara Penderita Demam Berdarah Dengue dan Demam Dengue Setiabudi, Djatnika; Setiabudiawan, Budi; Parwati, Ida; Garna, Herry
Majalah Kedokteran Bandung Vol 45, No 4 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1240.077 KB)

Abstract

Manifestasi klinis infeksi virus dengue dapat berupa demam dengue atau keadaan yang lebih berat yaitu demam berdarah dengue. Patogenesis yang menerangkan hal tersebut belum jelas. Teori yang sering dikemukakan yaitu pada penyakit dengue berat terjadi peningkatan kadar mediator proinflamasi. Tujuan penelitian ini untuk melihat perbedaan kadar platelet activating factor plasma penderita demam berdarah dengue dengan demam dengue. Penelitian observasional dengan rancangan potong lintang dilakukan pada Januari–Februari 2013. Subjek penelitian adalah penderita dengue usia 1–14 tahun yang dirawat di Rumah Sakit Dr. Hasan Sadikin Bandung, RSUD Kota Bandung (Ujungberung), dan RSUD Kota Cimahi (Cibabat). Diagnosis dengue dikonfirmasi dengan pemeriksaan antigen nonstruktural-1 dan atau pemeriksaan serologis imunoglobulin M dan G. Sampel darah fase demam, kritis dan pemulihan diambil untuk pemeriksaan kadar platelet activating factor plasma menggunakan metode enzymelinked immunosorbent assay. Selama kurun waktu penelitian didapat 26 penderita dengue, terdiri atas 14 kasus demam dengue dan 12 demam berdarah dengue. Kadar platelet activating factor plasma pada fase kritis penderita demam berdarah dengue [541,45 (239,30–2.449,00)] pg/mL lebih tinggi secara bermakna dibandingkan dengan penderita demam dengue [289,55 (149,50–961,50)] pg/mL; p=0,007. Simpulan, kadar platelet activating factor plasma pada fase kritis penderita demam berdarah dengue lebih tinggi daripada penderita demam dengue. [MKB. 2013;45(4):251–6]Kata kunci: Demam berdarah dengue, demam dengue, platelet activating factor The Difference of Platelet Activating Factor Plasma Level between Dengue Hemorrhagic Fever and Dengue Fever patientsDengue virus infection can manifest as dengue fever and, more severely, as dengue hemorrhagic fever. Their pathogenesis until now is not fully understood. One of the most favorable theories stated the presence of increasing titer of pro-inflammatory mediator in severe dengue. The aim of this study was to determine the difference of plasma platelet activating factor titer between dengue hemorrhagic fever and dengue fever patients. This observational study with cross sectional design was conducted during January–February 2013. Subjects were dengue patients, 1 to 14 years old, hospitalized at Dr. Hasan Sadikin General Hospital, Bandung District Hospital (Ujungberung), and Cimahi District Hospital (Cibabat). Dengue cases were confirmed based on nonstructural-1 antigen and/or immunoglobulin M and G rapid test. Blood samples from febrile, critical and recovery phase were drawn for the examination of platelet activating factor titer using the enzyme-linked immunosorbent assay method. There were 26 dengue cases (14 as dengue fever and 12 as dengue hemorrhagic fever). Plasma platelet activating factor titer at the critical phase was significantly higher in dengue hemorrhagic fever patients [541.45 (239.30–2,449.00)] pg/mL compared to dengue fever patients [289.55 (149.50–961.50)] pg/mL; p=0.007. In conclusion, plasma platelet activating factor titer at the critical phase is higher in dengue hemorrhagic fever patients than in dengue fever patients. [MKB. 2013;45(4):251–6]Key words: Dengue hemorrhagic fever, dengue fever, platelet activating factor DOI: http://dx.doi.org/10.15395/mkb.v45n4.172
Prevalensi Sarkopenia pada Lansia di Komunitas (Community Dwelling) berdasarkan Dua Nilai Cut-off Parameter Diagnosis Vitriana, Vitriana; Defi, Irma Ruslina; Irawan, Gaga Nugraha; Setiabudiawan, Budi
Majalah Kedokteran Bandung Vol 48, No 3 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v48n3.417

Abstract

Sarkopenia, sindrom penurunan massa dan fungsi otot terkait usia dapat mengurangi kualitas hidup dan peningkatan mortalitas pada lanjut usia (lansia). Banyak metode penapisan dan definisi operasional menyebabkan angka prevalensi sarkopenia bervariasi di dunia. Penelitian ini bertujuan mengetahui prevalensi sarkopenia pada lansia yang tinggal di komunitas berdasarkan massa otot yang diukur dengan bioimpedance analysis, kekuatan genggam tangan menggunakan hand dynamometer, serta performa fisik melalui uji jalan 6 menit dengan mempergunakan dua nilai cut-off, nilai rekomendasi Asian Working Group for Sarcopenia (AWGS) dan nilai populasi lansia Taiwan karena belum didapatkan nilai cut-off populasi lansia Indonesia. Penelitian deskriptif potong lintang pada 229 partisipan (71 orang laki-laki dan 158 orang perempuan) dengan menggunakan teknik consecutive sampling dilakukan pada bulan Agustus sampai Desember 2014 pada populasi lansia di Kota Bandung dan Jatinangor. Hasil penelitian menunjukkan angka prevalensi sarkopenia berdasarkan nilai cut-off rekomendasi AWGS adalah 9,1% (7,4% untuk laki-laki dan 1,7% untuk perempuan), sedangkan prevalensi sarkopenia berdasarkan nilai cut-off populasi Taiwan sebesar 40,6% (20,1% untuk laki-laki dan 20,5% untuk perempuan). Perbedaan prevalensi yang cukup besar mendorong diperlukan penetapan nilai cut-off parameter diagnosis sarkopenia spesifik pada populasi lansia Indonesia yang tinggal di komunitas untuk dapat menentukan prevalensi sarkopenia lebih akurat. [MKB. 2016;48(3):164–70]Kata kunci: Cut-off, lansia, komunitas, prevalensi, sarkopenia Sarcopenia Prevalence In Community-Dwelling Elderly based on Two Cut-off Points Diagnosis ParametersSarcopenia, aging muscle mass loss, and function syndromes can lead to decreased quality of life and increased elderly mortality. The availability of various screening methods and operational definitions in different studies has produced different findings of sarcopenia prevalence. The purpose of this study was to discover the prevalence of sarcopenia in Indonesian community-dwelling elderly based on muscle mass measured by bioimpedance analysis, handgrip strength using hand dynamometer, and physical performance based on six minutes walking test  with two different cut-off point parameters of sarcopenia, i.e. the cut-off point recommended by Asian Working Group for Sarcopenia (AWGS) and the cut-off point based on the reference used in  Taiwan elderly population reference due to the lack of references for Indonesian elderly population. A cross-sectional study was conducted to 229 participants (71 men and 158 women) from the community-dwelling elderly population between August and December 2014 in Bandung and Jatinangor. The results of the study showed that the sarcopenia prevalence in this study based on AWGS was 9.1% (7.4% in men and 1.7% in women) while the prevalence based on the Taiwan reference revealed a prevalence of 40.6% (20.1% in men and 20.5% in women). This highly different prevalences shows the importance of defining a specific cut-off point for elderly population in community-dwelling Indonesia to get a more accurate sarcopenia prevalence. [MKB. 2016;48(3):164–70Key words: Community dwelling, cut-off, elderly, prevalence, sarcopenia
The Association Between Initial Solid Food and Atopy in Children with or without Family History of Atopic Disease Perdana, Nanan Surya; Setiabudiawan, Budi; Kartasasmita, Cissy B.
Majalah Kedokteran Bandung Vol 42, No 1
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Atopic diseases are the most common chronic diseases in childhood. Their incidence has a tendency to increase recently. The tendency of atopy could be triggered by many factors originated in the early life, including early introduction of solid food. To investigate the association between initial solid food and atopy, an analytic comparative study with historical cohort design was conducted from May to June 2006 in Pediatric Department of Hasan Sadikin Hospital Bandung. It was the second phase study of 'allergic prevalence and risk factors identification in the first two years of life'. Out of 800 children in Garuda, Padasuka, and Babakansari Primary Health Care Center who were included in the first phase of the study, 749 children were eligible to continue the second phase of the study, 284 children were randomized into two groups of children with and without family history of atopic disease consisting of 142 children each. They then underwent skin prick test. History of initiation time of solid food were obtained from their parents. To analyze the data chi-square and odds ratio with 95% confidence interval were used. Among 284 children who fullfilled the inclusion criteria, 50% had family history of atopic disease. Atopy was found in 28.2% children, 32.4% with family history of atopic disease and 23.9% without family history of atopic disease. There was no significant correlation between family history of atopic disease and atopy (p=0.113). There was a high risk for atopy related to initial solid food (OR = 4.50, 95%CI = 1.96-10.74, p < 0.001). The difference of atopy was strongly significant between children who had initial solid food at the age of <6 months and at the age of >6 months whether or not the children had family history of atopic disease (p=0.016 and p=0.002). Conclusions: A significant increase in the risk of childhood atopy occured if initial solid food is given at the age of <6 months, whether or not the children have family history of atopic disease.Hubungan antara Waktu Pemberian Makanan Pendamping ASI dan Kejadian Atopi pada Anak dengan atau Tanpa Riwayat Penyakit Atopik dalam KeluargaPenyakit atopik merupakan penyakit kronik yang paling sering ditemukan pada anak. Angka kejadian penyakit atopik cenderung meningkat dari tahun ke tahun. Kecenderungan atopi atau timbulnya penyakit atopik dapat dicetuskan oleh faktor faktor yang berpengaruh di awal kehidupan, salah satunya adalah pemberian makanan pendamping ASI (MP ASI). Untuk mengetahui hubungan antara waktu pemberian MP ASI dan kejadian atopi dilakukan penelitian analitik komparatif dengan rancangan historical cohort. Penelitian dilakukan pada bulan Mei-Juni 2006 di Bagian Ilmu Kesehatan Anak Rumah Sakit Hasan Sadikin Bandung. Penelitian ini merupakan fase kedua dari penelitian “Prevalens alergi dan identifikasi faktor risiko pada dua tahun pertama kehidupan”. Penelitian dilakukan di Puskesmas Garuda, Padasuka, dan Babakansari. Dari 800 anak yang mengikuti fase I, sebanyak 749 anak dapat diteliti pada penelitian fase II. Dengan teknik sampling secara acak terpilih 142 anak, masing-masing dari  kelompok dengan dan tanpa riwayat penyakit atopik dalam keluarga. Selanjutnya dilakukan pemeriksaan uji tusuk kulit dan ditanyakan mengenai riwayat pemberian MP ASI. Analisis statistik yang digunakan adalah uji kai-kuadrat dan Odds ratio dengan IK95%. Dua ratus delapan puluh empat anak memenuhi kriteria inklusi penelitian. Dari jumlah tersebut diperoleh 50% anak dengan riwayat penyakit atopik dalam keluarga. Atopi didapatkan pada 28,2% anak, 32,4% di antaranya dengan riwayat penyakit atopik dan 23,9% tanpa riwayat penyakit atopik dalam keluarga. Tidak terdapat hubungan yang bermakna antara anak dengan riwayat penyakit atopik dalam keluarga dan kejadian atopi (p=0,113). Dua ratus delapan (73,2%) anak mendapat MP ASI pada usia <6 bulan, 76 (26,8%) anak mendapat ASI pada usia >6 bulan. Kejadian atopi berbeda bermakna antara anak yang mendapat MP ASI pada usia <6 bulan dan >6 bulan (OR=4,50; IK95%=1,96-10,47; p<0,001), baik pada kelompok anak dengan riwayat penyakit atopik (OR=3,38; IK95%=1,12-10,86; p=0,016) maupun tanpa riwayat penyakit atopik (OR=6,08; IK95%=1,63-26,72, p=0,002) dalam keluarga. Kesimpulan: Pemberian MP ASI pada usia <6 bulan meningkatkan risiko terjadinya atopi, baik pada kelompok anak dengan atau tanpa riwayat penyakit atopik dalam keluarga.DOI: http://dx.doi.org/10.15395/mkb.v42n1.6 
HUBUNGAN ANTARA ATOPI DENGAN RIWAYAT PENYAKIT ALERGI DALAM KELUARGA DAN MANIFESTASI PENYAKIT ALERGI PADA BALITA Weninggalih, Endah; Kartasasmita, Cissy B.; Setiabudiawan, Budi
Majalah Kedokteran Bandung Vol 41, No 1
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Prevalensii penyakit alergi cenderung meningkat dalam dekade terakhir. Hal ini disebabkan karena faktor genetik dan lingkungan. Faktor genetik dibuktikan dengan riwayat penyakit alergi dalam keluarga. Penyakit alergi merupakan gejala alergi pada individu yang atopi. Penelitian ini bertujuan untuk mengetahui apakah atopi dan riwayat penyakit alergi dalam keluarga merupakan faktor risiko timbulnya manifestasi penyakit alergi. Penelitian dilakukan di Puskesmas Garuda, Babakan Sari dan Padasuka Bandung selama bulan Februari-Maret 2007 dengan rancangan cross sectional. Subjek yang telah mempunyai data hasil uji tusuk kulit (UTK) dan ada tidaknya riwayat penyakit alergi dalam keluarga dilakukan pengisian kuesioner standar The International Study of Asthma and Allergies in Childhood (ISAAC) dan pemeriksaan fisis. Subjek dinyatakan atopi bila hasil UTK positif. Hubungan antara variabel dianalisis dengan metode Ki kuadrat dan rumus Mantel Haenszel untuk mengkontrol confounding variabel. Jumlah subjek sebanyak 260 anak (92%), terdiri dari 130 anak dengan riwayat penyakit alergi dalam keluarga dan 130 anak tanpa riwayat penyakit alergi dalam keluarga. Berdasarkan UTK didapat 70 anak atopi dan 190 anak nonatopi. Manifestasi penyakit alergi terdapat pada 86 anak (33,08%). Manifestasi terbanyak adalah rinitis alergika 41 anak (15,77%),kemudian dermatitis atopik 18 anak (6,92%), dan asma 5 anak (1,92%). Kejadian manifestasi penyakit alergi terdapat pada 57,1% anak atopi dan 24,2% anak nonatopi. Kejadian manifestasi penyakit alergi terdapat pada 41,5% anak dengan riwayat penyakit alergi dalam keluarga dan 24,6% anak tanpa riwayat penyakit alergi dalam keluarga. Atopi mempunyai hubungan yang lebih kuat dengan manifestasi penyakit alergi pada balita, namun riwayat penyakit alergi dalam keluarga juga mempunyai hubungan sehingga merupakan hal yang penting untuk ditanyakan kepada orang tua.Kata kunci: Manifestasi penyakit alergi, atopi, riwayat penyakit alergi dalam keluargaASSOSIATION BETWEEN ATOPY WITH ALLERGIC HISTORY IN THE FAMILY AND ALLERGIC DISEASE IN UNDER FIVE YEAR OLD CHILDRENThere was an increase in prevalence of allergic diseases in the last decade. This was because of genetic and environmental factors. Genetic factor were proven by allergic history in the family. Allergic reaction in individu with atopy determined as allergic disease.The aim of this study was to know whether atopy and family allergic disease were risk factors for the occurrence of allergic disease manifestation. This study was conducted at Garuda, Padasuka and Babakan Sari Primary Health Center in Bandung, Indonesia, during February-March 2007, with cross sectional designed. Subjects with skin prick test (SPT) result and history or no history allergic disease data were questioned by The International Study of Asthma and Allergies in Childhood (ISAAC) and physical examination. Data were analyzed >using chi square and Mantel Haenszel test for confounding variables. A total of 260 (92%) children joined the third phase; consisted of 130 children with family history of allergic and 130 children without family history of allergic. Based of SPT consisted of 70 children with positive results and 190 children with negative results. The incidence of allergic disease was confirmed in 86 (33.08%) children: 41 (15.77%) children with allergic rhinitis, 18 (6.92%) children withatopic dermatitis, and 5 (1.92%) with asthma. Allergic diseases manifestation were confirmed in 57.1% atopy children and 24.2% nonatopy children. Allergic diseases manifestation were confirmed in 41.5% children with and 24.6% children without family history of allergic. Atopy has stronger association with allergic disease manifestation in under five children, but family history of allergic also has association so it's important to ask parents.Key words: Allergic diseases manifestation, atopy, family history of allergic
Effect of Stunting Education Counseling with Booklet Media on Parental Knowledge and Attitude As an Effort to Overcome Stunting Triatmaja, Dendy; Lestari, Keri; Setiabudiawan, Budi
Journal of Maternal and Child Health Vol. 8 No. 1 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.191 KB) | DOI: 10.26911/thejmch.2023.08.01.10

Abstract

Background: Stunting is developmental disorders experienced by children due to poor nutrition, repeated infections, and inadequate psychosocial stimulation. The problem of stunting in children under five shows an average rate of 35.3% in West Java. Stunting is a problem because it is asso­ciated with an increased risk of disease and death, suboptimal brain development, which results in delayed motor development and stunted mental growth. Jamika sub-district has a high prevalence of stunting under five in West Java, which is 23.7%. Pharmacists as Agents of Change can also optimize their role by providing information and education on stunting prevention. Subjects and Method: This study uses a design Pretest-posttest control group design at the Posyandu, Jamika Village, from February to April 2022. The total sample in this study was 30 people who were taken from mothers who had toddler 0-24 months of age. Samples were obtained by simple random sampling. The dependent attitudes of parents. The independent variable was knowledge. The data that has been collected is then analyzed using chi square test and odds ratio (OR). Results: Good knowledge increased the attitude of parents in efforts to overcome stunting at Posyandu, Jamaika village. Parents with good knowledge increased attitude by 1.40 times to have a positive attitude in efforts to overcome stunting, and this result is statistically significant (OR= 1.40; 95% CI= 0.87 to 2.23; p= 0.008). Conclusion: There was a relationship between good knowledge with attitude of parents as an effort to overcome stunting in the Posyandu, Jamika village with booklet media. Keywords: stunting, booklet, knowledge, attitudes, parents. Correspondence:Dendy Triatmaja. Master of Clinical Pharmacy Study Program.  Universitas Padjadjaran. Jl. Raya Bandung Sumedang KM 21, Jatinangor 45363. Email: dendy20001@unpad.ac.id. Mobile: 082250888878.
Pregnant Human Myometrial 1-41 Cell Viability Test on Vitamin D Administration Aziz, Muhammad Alamsyah; Krisnadi, Sofie Rifayani; Handono, Budi; Setiabudiawan, Budi
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n3.2750

Abstract

Background: Preterm labor is one of the universal causes of perinatal mortality worldwide. One of the causes of preterm labor is uterine muscle integrity problems. Some mechanistic studies show insight into vitamin D activity’s possible role in the injured muscle. This study aimed to determine whether vitamin D can increase muscle cell viability.Methods: This experimental research used human smooth muscle uterine myometrium cell line pregnant human myometrial (PHM) 1-41. The cells were cultured for 24 hours in hypoxia condition, then incubated with several doses of vitamin D. The PHM1-41 cell viability was measured using spectrophotometry. Data analysis was conducted using IBM SPSS 24.0. A p-value <0.05 was considered statistically significant. Results: The result showed that the minimum level of muscle cell viability after vitamin D incubation was with 300 nM administration, and the maximum level was after 10nM (88.57%+4.48 and 96.21%+2.13 respectively).Conclusions: Vitamin D at a specific dose can improve cell availability. The optimal dose to improve cell viability is 10 nM. 
Co-Authors Ani Melani Maskoen Aziz, Muhammad Alamsyah Budi Handono Cissy B. Kartasasmita Citra Amelinda Djatnika Setiabudi Fedri Ruluwedrata Rinawan Gaga Irawan Nugraha Gartika Sapartini Henni Djuhaeni Herry Garna Hesti Puspasari Ida Parwati Irma Ruslina Defi Johanes C. Mose Keri Lestari Kuswandewi Mutyara, Kuswandewi M. Thaufiq S. Boesoirie, M. Thaufiq S. Melati Sudiro Perdana, Nanan Surya Putria Rayani Raden Tina Dewi Judistiani Reni Ghrahani RINI SUNDARI, RINI Saputri, R. Ayu Hardianti Sheba, Shiane Hanako Sofie R. Krisnadi Sunjaya, Deni K. Teti Madiadipoera Tetty Yuniati Thaufiq S. Boesoirie Triatmaja, Dendy Vitriana Vitriana Weninggalih, Endah