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All Journal Jurnal Bios Logos Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Jurnal Keperawatan dan Fisioterapi (JKF) Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Science Midwifery Jurnal Penelitian Farmasi dan Herbal Jurnal Antara Abdimas Keperawatan Jurnal Pengmas Kestra (JPK) Jurnal Pengabdian Masyarakat Ilmu Kesehatan

Romaulianna Theresia Marbun

Institut Kesehatan Medistra Lubuk Pakam

Author-ID : 3845954

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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SEMINAR PEMBUATAN SEDIAAN EYESHADOW COMPACT POWDER DENGAN EKSTRAK DAUN BAYAM MERAH (Amaranthus tricolor L.)SEBAGAI PEWARNA ALAMI Cucu Arum Dwi Cahya; Mega Silalahi; Romauli Anna Teresia Marbun
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Berbagai jenis kosmetik yang sering kali diminati bagi para wanita yaitu eye shadow.Pada sebagian produk eye shadow masih terdapat penyalahgunaan pewarna tekstil yang berbahaya jika digunakan bagi tubuh.Daun bayam merah (Amaranthus tricolor L.) mempunyai pigmen betasianin yang dapat dijadikan pewarna alami pada sediaan eye shadow compact powder. Penelitian ini bertujuan untuk membuat sediaan eye shadow compact powder dengan menggunakan ekstrak daun bayam merah sebagai pewarna alami serta memenuhi persyaratan mutu fisik dan tidak mengiritasi kulit.Daun bayam merah segar dilakukan ekstraksi dengan metode maserasi dengan menggunakan pelarut etanol 70% dan ditambahkan asam sitrat, kemudian pelarut diuapkan dengan bantuan alat rotary evaporator pada suhu 50°C, kemudian dipekatkan dengan waterbath (penangas air) pada suhu 78°C sampai didapatkan ekstrak kental. Kemudian diformulasikan ke dalam bentuk sediaan eye shadow compact powder dengan menggunakan kaolin, zink stearat, nipagin, isopropyl miristat, lanolin, oleum rosae, dan talkum. Dengan variasi konsentrasi ekstrak daun bayam merah F0 (Blanko), F1 (8%), F2 (12%) dan F3 (18%). Kemudian campuran serbuk dicetak dengan alat press. Selanjutnya dilakukan pemeriksaan persyaratan mutu fisik sediaan eye shadow compact powder yaitu uji dispersi warna (homogenitas), uji poles, uji kerapuhan, dan uji stabilitas terhadap bentuk,warna dan aroma pada penyimpanan suhu kamar selam 30 hari, serta uji iritasi terhadap sediaan F0 (Blanko), F1 (8%), F2 (12%) dan F3 (18%). Berdasarkan hasil yang diperoleh semua sediaan F0 (Blanko), F1 (8%), F2 (12%) dan F3 (18%) homogen terdispersi merata, tidak rapuh, stabil dalam penyimpanan suhu kamar selama 30 hari, dan tidak mengiritasi kulit. Namun pada pemeriksaan uji oles pada sediaan F3 (18%) memiliki daya oles yang kurang baik dikarenakan perlu 5 kali pengolesan agar warna terlihat jelas menempel pada kulit sedangkan pada sediaan F0 (Blanko), F1 (8%) dan F2 (12%) cukup dengan 3 kali pengolesan warna sudah terlihat dan menempel.

SOSIALISASI EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) SEBAGAI MASKER GEL PEEL OFF Dewi Kartika; Lulu Atikah; Romauli Anna Teresia Marbun
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Fragrant pandans are plants that contain chemical alkaloids, flavonoids, tannins, and polyphenols. Fragrant pandan leaves can be formulated as a gel peel off mask to moisturize the skin. Before formulating fragrant pandan leaves in the extract first and made in several concentrations to see the difference in humidity. 0% (blanko), 2.5%, and 5% are made in 30 gram preparations. Tests performed on preparations include organoleptic tests, homogeneity, pH, dry time preparation, and humidity. Homogeneity test results showed homogeneous preparations, pH in the range of 6.0 that are relatively safe on the surface of the facial skin. The preparation time dries for 30 minutes and meets the drying time requirements. The greater the concentration, the ability to moisturize the skin the better.

THE SOCIALIZATION OF RIMBANG FRUIT ACTIVITY TEST RESULTS (Solanum torvum Swartz) BY HYPERSENSITIVITY METHOD SLOW TYPE Romauli Anna Marbun; Imelda Oktaviani Br Sihombing; Kristian Cahayani Zebua
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 1 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Immunomodulators are compounds that improve the immune system. One of the plants that has immunomodulatory activity is Rimbang Fruit (Solanum torvum swartz). The purpose of this service is to inform the immunomodulatory effect of rimbang ethanol extract in male rats which is the result of research. Research related to immunomodulatory activity was determined using a digital plethysmograph by measuring the difference between the volume of swelling of the last leg and the volume of swelling of the first leg. The treatment group was divided into 5 groups. Each group consisted of 5 CMC-Na 0.5% mice (negative control), Imboost 25 mg/kg BB (positive control), doses of EEBR100, 200 and 400 mg/kg BB and S. aureus antigens.

Penetapan Kadar Flavonoid Total pada Daun Karamunting (Rhodomyrtus tomentosa) sebagai Bahan Berpotensi Antioksidan dengan Metode Spektrofotometri UV-Visible Romauli Anna Teresia Marbun
Jurnal Dunia Farmasi Vol 7, No 2 (2023): Edisi April
Publisher : Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v7i2.5465

Pendahuluan: Bahan alam berpotensi obat menjadi fokus utama para peneliti masa kini. Pemeriksaan senyawa yang terkandung di dalam bahan alam tersebut menjadi hal utama yang dilakukan. Kuersetin merupakan salah satu zat aktif golongan flavonoid yang memiliki aktivitas biologis yang kuat. Kadar kuersetin menjadi marker seberapa besar potensi suatu tanaman menjadi fitofarmaka ke depan. Daun karamunting (Rhodomyrtus tomentosa) memiliki kandungan flavonoid, glikosida, saponin, dan tannin. Daun karamunting berpotensi sebagai antiabetes, antibakteri, dan antikolesterol. Tujuan: Untuk menetapkan kadar flavonoid total dari daun karamunting dilakukan dengan menggunakan metode spektrofotometri UV-Visible. Metode: Penelitian yang digunakan eksperimental menggunakan daun karamunting yang diambil dari Ajibata Kabupaten Toba. Ektraksi yang digunakan adalah metode maserasi dengan menggunakan etanol 96%. Penetapan kadar flavonoid total dilakukan dengan pembuatan larutan baku kuersetin, penentuan panjang gelombang maksimum kuersetin, pengukuran kadar flavonoid total. Kurva kalibrasi dibuat dengan mengukur baku kuersetin pada konsentrasi 60,70,80,90, dan 100 ppm. Setelah itu dilakukan pengukuran kadar flavonoid total. Hasil: Rata-rata Kadar Flavonoid total dengan standar kuersetin dalam Ekstrak adalah sebesar 1,33% dengan tiga kali ulangan. Kesimpulan: Hal ini menunjukkan kadar kuersetin yang terkandung dalam daun karamunting bisa digunakan untuk bahan antioksidan.

THE SOCIALIZATION ABOUT THE RIMBANG FRUIT ACTIVITY TEST (SOLANUM TORVUM SWARTZ) AS AN IMMUNOSTIMULATOR: SOCIALIZATION ABOUT THE RIMBANG FRUIT ACTIVITY TEST (SOLANUM TORVUM SWARTZ) AS AN IMMUNOSTIMULATOR Marbun, Romauli Anna Teresia; Br Situmorang, Novidawati; Wahyuni, Siti
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 2 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Decreased immune system function can occur when the invasion of foreign substances cannot be balanced by immune cells. So, we need substances or materials that can improve the immune system and increase its regulation. Rimbang fruit (Solanum torvum Swartz) is a native vegetable that has been consumed by local people for a long time. Previous research stated that rimbang fruit is rich in phenolic compounds, namely flavonoid derivatives, namely flavonols (quercetin, kaempferol, and myricetin) and flavones (apigenin and luteolin). These secondary metabolites indicate that rimbang fruit has the potential to regulate the regulation of the immune system supported by its high antioxidant power. The research method used experimental methods, extraction method with 96% ethanol solvent maceration method. Variations in the dose of rimbang fruit extract used were doses of 50%, 100%, 200%, and 400%. The positive control used was Levamisole. The negative control used was CMC-Na 0.5%. The immunomodulator test method uses the antibody titer method using male rats as test animals. Immunogens used sheep red blood cells. Information provided to pharmacy students. From this it was concluded that the rimbang fruit extract had an immunostimulating effect at an optimal dose of 400 mg/kg body weight. These findings are shared with students and the public through Zoom meetings to help them understand the benefits of rimbang as an immunostimulator.

Seminar Evaluation of the Use of Antihypertensive Drugs in Hospitalized Patients Suffering From Hypertension in Grandmed Hospital Lubuk Pakam in 2023 Marbun, Romauli Anna; Nainggolan, Hotdoriska; Wahyuni, Siti; Sihombing, Yanna Rotua; Parinduri, Anggi Isnani
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 1 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i1.1777

Proper treatment is needed to control high blood pressure, including drugs to minimize the strength of blood flow. This study aims to obtain information and knowledge related to the pattern of taking blood flow strength drugs in high blood patients located at Grandmed Lubuk Pakam Hospital 2023. This type of research is an illustrative study using descriptive design and retrospective data. Research shows the use of high blood pressure drugs by hypertensive patients at Grandmed Lubuk Pakam Hospital in 2023 are as follows: Partial accuracy, namely 56 hypertensive patients without complications, right indication 100%, right drug 98.21%, right patient 100%, and right dose 100%. It can be concluded that hypertensive patients at Grandmed Lubuk Pakam Hospital meet the criteria for the right patient, right indication and right dose. The description of the use of high blood pressure drugs at Grandmed Lubuk Pakam Hospital is: (0.1%), candesartan (46.4%), bisoprolol (7.1%), captopril (8.9%), valsartan (7.1%) and furosemide (3.6%). Then community service activities were carried out with the target of 125 Pharmacy students to increase student knowledge related to the use of antihypertensive drugs used in hospitals. The socialization was carried out virtually via zoom and pre-test and post-test were given to assess students' understanding of the service material. The questionnaire is presented in the form of a googleform as an assessment of feedback on the results of socialization materials issued after the activity is completed. The activity was also filled with responses and questions and answers with service participants. The conclusion obtained is that 87% of students understand the use of hypertension drugs very well, 12% understand well, and 1% understand the use of hypertension drugs enough.

Socialization and Evaluation of The Level of Compliance of Tuberculosis Patients to The Use Anti-Tuberculosis Drugs to Pharmacy Students of The Lubuk Pakam Medical Health Institute in 2023 Marbun, Romauli Anna; Sinaga, Falentina; Maharani, Anisa; Sihombing, Yanna Rotua; Anggraeni, Ratih
JURNAL PENGMAS KESTRA (JPK) Vol. 4 No. 1 (2024): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v4i1.2033

The incidence of Tuberculosis (TB) is a health issue that must be paid attention to, especially at the Limapuluh Community Health Center. This health center is a health service center in the Fifty District which experiences a high incidence of TB, with the number of TB cases in 2022 increasing from the previous year. The level of patient compliance with treatment is one of the determining factors for the success of therapy. This study aims to provide an understanding of the factors that influence the level of compliance of TB patients with the use of Anti-Tuberculosis Drugs (OAT) at the Limapuluh Community Health Center. The method of service carried out is in the form of communication, information and education related to the use of Anti-Tuberculosis Drugs. The socialization was carried out online through a zoom meeting with the presentation of material and continued with a pretest and posttest as a measuring tool regarding the increase in participants' understanding of the material presented. This activity was carried out on January 06, 2024 at 10.00-12.00 WIB. The results of this service are the counseling material provided to students seen from the posttest results which show that the understanding and increase in knowledge of the participants is good compared to the results of the previous pretest points. In conclusion, students who take part in this activity can further explore the factors that affect patient compliance in taking OAT drugs so that similar activities can be carried out regularly to prevent errors in the use of Anti Tuberculosis drugs.

IDENTIFIKASI KADAR VITAMIN C PADA DAGING DAN KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUS) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Syarifuddin, Aminah Nur; Zantrie, Rezky; Teresia Marbun, Romauli Anna
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Introduction: Vitamin C is one of the nutrition acted as a antioxidants and effective addres free radicals can be destructive cells or tissue. Fruits are a source of vitamins C, which is a dragon red. Part of the dragon red during this rarely used is the skin. The dragon fruit is very useful to health, but in fact only thought of as waste farming has yet to be used as a good. This study aims to determine comparison levels of vitamin C on the flesh and the dragon red (Hylocereus polyrhizus) with a method spectrophotometry UV-Visible. Method: This type of research using the method of true experimental reseach stage includes preparation of samples, qualitative test,quantitative test, making the solution of the parent raw materials, determination of wavelength of vitamin C and manufacture of the calibration curve. The sample of this study is the flesh and the dragon red (Hylocereus polyrhizus). Results: Based on the results revealed that the fles and the dragon red (Hylocereus polyrhizus) contain vitamin C. Discussion: Levels of vitamin C on the flesh the dragon red of 0.05888 mg/mL and The levels of vitamin C on the skin the dragon red of 0.02533 mg/mL .

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN PIRDOT (SAURAUIA VULCANI KORTH.) TERHADAP BAKTERI SALMONELLA THYPI Octora, Debi Dinha; Teresia Marbun, Romauli Anna; Koto, Rahmadona
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Indonesia is known for the many plants that are used as traditional medicine for disease prevention, including the leaves of the pirdot (Saurauia vulcani Korth) family Actinidiaceae. This study aims to determine the antibacterial activity of ethanol extract of pirdot leaves (Saurauia vulcani Korth). The results of the characterization of pirdot leaf simplicia powder were obtained 3.99% water content, water soluble extract 12.15%, ethanol soluble extract 8.89%, total ash content 9.97%, insoluble ash content in acids 3.17%. The results of phytochemical screening tests contained the chemical compounds of steroids / triterpenoids, flavonoids, glycosides, tannins and saponins. Ethanol extract of pirdot leaf has antibacterial activity against Salmonella typhi bacteria. The treatment consisted of 4 concentrations, pirdot leaf extract with 3 repetitions, each blank (DMSO), 50 mg / ml, 100 mg / ml, 150mg / ml, 200 mg / ml. After that, it was incubated for 24 hours at 37oC. Inhibition zone diameter observations were made using calipers. The results obtained showed that administration of pirdot leaf extract at concentrations of 50 mg / ml, 100 mg / ml, 150 mg / ml and 200 mg / ml can inhibit the growth of Salmonella typhi bacteria. The results of the antibacterial activity test of pirdot leaf ethanol extract against Salmonella typhi bacteria obtained the highest inhibitory concentration of 200 mg / ml with a diameter of 20.48 mm.

UJI SENYAWA FLAVONOID TOTAL DARI EKSTRAK ETANOL HERBA BINARA (ARTEMISIA ANNUA) MENGGUNAKAN HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) TAHUN 2019 Purba, Novandi; Sinurat, Jhon Patar; Marbun, Romauli Anna Teresia
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

ABSTRAK Herba binara (Artemisia Annua) is one of the plants that contains flavonoids which are efficacious as antioxidants and anticancer. The purpose of this study was to determine the total flavonoid compounds contained in ethanol extract of binara herbs (Artemisia Annua). Compounds in ethanol extract of binara herbs were identified by phytochemical screening. The results showed that the ethanol extract of binara herbs contained alkaloids, flavonoids, saponins, and tannins. Extraction was carried out in two stages, namely maceration stage with 96% ethanol and fat removal stage by hydrolysis using distilled water solvent. The extract was partitioned with ethyl acetate and n-hexane solvents, then the partitions were examined by TLC using the mobile phase of chloroform and ethyl acetate (7: 3). Ribbon patches that have the same Rf and color prices as the initial detection are taken and searched. Then analyzed using High Performance Liquid Chromatography (HPLC). Based on the wavelength as well as the TLC test, a partial structure which was strongly suspected of total flavonoids was 0.93 g. Kata Kunci :Herba Binara (Artemisia Annua), flavonoid, KLT, High Performance Liquid Chromatography(HPLC).

Co-Authors *, Yanna Rotua Sihombing Aminah Aminah Aminah Syarifudin Aritonang, Barita AROFATUL HIDAYAH Br Situmorang, Novidawati Cahya, Cucu Arum Dwi Dalimunthe, Juliana Dewi Kartika Dewi Kartika Dewi, Ayu Puspita Dicky Yuswardi Wiratma Elliya Siswanti Fatima, Nurdilla Friska Novita Pasaribu Harahap, Hasni Yaturramadhan Imelda Oktaviani Br Sihombing Juniaro Virgilius Dakhi Karmayanti Karokaro, Tati Murni Klara Jeina Br Tarigan Koto, Rahmadona Krisdianilo, Visensius Kristian Cahayani Zebua Kristian Cahayani Zebua Lenni Rismayanti Lestari, Dayana Loraetta Brety Sebayang Lubis, Amelia Hasana Lubis, Basyariah Lulu Atikah Maharani, Anisa Mega Silalahi Meirizal Jefrinaldi Meirizal Jefrinaldi Monica Marpaung, Dorima Montysory Silalahi Munthe, Novita Br Ginting Nainggolan, Hotdoriska Naro Ida Sari G. Manihuruk Nopita Sari Manalu, Dian Novidawati Boru Situmorang Novidawati Br Situmorang Novidawati Br Situmorang Novidawati Situmorang Novita Ginting Munthe Novitasari Sihaloho Octavian Ashido Nababan Octora, Debi Dinha Parinduri, Anggi Isnani Pranata, Chandra Purba, Novandi Putri, Puji Audina Radika Bella Fista Ginting Rahayu, Asvia Ratih anggraeni Ratih Anggraeni Ratih Anggraeni Ratih Anggraeni S, Aminah. SAADAH SIREGAR Sebayang, Loraetta Brety Siagian, Hartika Samgryce Sihombing, Yanna Sihombing, Yanna Rotua Sinaga, Falentina Sinurat, Jhon Patar Siregar, Saâ€™adah Siska, Fitri Siti Wahyuni Situmorang, Novidawati Br Sri Wahyuni Syarifuddin, Aminah Nur Syarifuddin, Shofian Vincentia Ade Rizky Yanna Rotua Sihombing Zantrie, Rezky Zebua, Kristian Cahayani

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