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All Journal Jurnal Biotek Medisiana Indonesia Jurnal Komunitas Farmasi Nasional Jurnal Kefarmasian Indonesia
Maratu Soleha
Basic Technology Center for Biomedical and Health, National Institute of Health and Research and Development
Chemistry Health Professions Medicine & Pharmacology Public Health

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Kadar Kolesterol Tinggi Dan Faktor-Faktor Yang Berpengaruh Terhadap Kadar Kolesterol Darah Soleha, Maratu
Jurnal Biotek Medisiana Indonesia Vol 1, No 2 (2012)
Publisher : Central Basic Biomedical and Health Technology

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Abstract

The cholesterol level in blood has become one of the risk factors of heart disease. One of the risk factors of heart disease is high cholesterol level. This article analysis variables that influence high cholesterol level in blood. Data were obtained from national health research in 2007 . Data consist of 21.178 respondents was clean up become 4.566 clean data ready to be analyze. Study design was cross sectional then analyzed with stata v. 9 followed by backward stepwise selection.Bivariate analysis shows gender, body mass index, sistole and diastole blood pressure, smoke habits and the responden who lack of strenuous activities have a tendency to hypercholesteromia risk.Key words: Hiperkolesterolemia, Indeks Massa Tubuh (IMT), sistolik, diastolik. AbstrakKadar kolesterol dalam darah yang tinggi merupakan salah satu faktor risiko penyakit jantung. Artikel ini membahas berbagai variabel yang mempengaruhi tingginya kadar kolesterol di dalam darah. Data untuk analisis diperoleh dari riset kesehatan dasar tahun 2007. Data terdiri dari 21.178 responden yang dibersihkan sehingga menjadi 4.566 data yang siap untuk dianalisis. Studi desain crossectional. Data dianalis dengan stata v.9 dilanjutkan dengan backward stepwise selection. Analisis dua variabel menunjukkan jenis kelamin, Indeks massa tubuh, tekanan darah, kebiasaan merokok dan kurangnya latihan fisik memiliki risiko hypercholesteromia.Key words: Hiperkolesterolemia, sistolik, diastolik.
Aktivitas Aktivitas Antibakteri Ekstrak Etanol 96% Pada Daun Tua Medang Pirawas (Litsea elliptica Blume) Terhadap Bakteri Staphylococcus aureus: Aktivitas Antibakteri Ekstrak Etanol 96% Pada Daun Tua Medang Pirawas (Litsea elliptica Blume) Terhadap Bakteri Staphylococcus aureus SOLEHA, MARATU; AULIA RACHMA, FARADIVA; AGUSTINA, IKA; EFRILIA, MEGA; SYAHPUTRA, GURITNO
Jurnal Komunitas Farmasi Nasional Vol. 4 No. 1 (2024): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Litsea elliptica Blume, is one type of traditional medicinal plant that is widely used by the Indonesian people. This symplisia can be used to treat headaches, fever, stomach ulcers, and also as an insect repellent. Litsea elliptica Blume also has antimicrobial and antioxidant properties. Objective: This study aims to determine whether 96% ethanol extract of Litsea elliptica Blume leaves has antibacterial activity against Staphylococcus aureus bacteria. Methods: This research is a laboratory experiment with descriptive quantitative method conducted in this study to test the antibacterial properties of 96% ethanol extract of Medang Pirawas (Litsea elliptica Blume) against Staphylococcus aureus bacteria. Results: The yield of the thick extract of Litsea elliptica Blume was 19.36 %, and the classes of secondary metabolite compounds found were phenols, flavonoids, saponins, tannins, alkaloids, and terpenoids. The results of the antibacterial activity test of the viscous extract of Litsea elliptica Blume did not show antimicrobial properties against the growth of Staphylococcus aureus, which was characterized by not forming a clear zone on the media. Conclusion: From these results it can be concluded that there is no antibacterial activity of ethanol extract of medang pirawas (Litsea elliptica Blume) leaves against the growth of Staphylococcus aureus bacteria.
Profil Penggunaan Obat Antiinflamasi Nonstreoid di Indonesia Soleha, Maratu; Isnawati, Ani; Fitri, Nyoman; Adelina, Rosa; Soblia, Hamim Tsalis; Winarsih, Winarsih
Jurnal Kefarmasian Indonesia VOLUME 8, NOMOR 2, AGUSTUS 2018
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v8i2.316

Abstract

Nonsteroid Antiinflamation Drugs (NSAIDs) are available in drug store and be bought as a pain relief. Basic Health Research (Riskesdas) 2013 study the medicines stored in household. Basic Health Research (Riskesdas) 2013 was held in 33 provinces and 497 districts in Indonesia. The research encompasses 300.000 households in 12.000 blocks cencus. The participants were designated households and its member of the family. The study were interviewing the participants to obtain data of all drugs that are stored and used, including traditional medicines. The data including the brand, indication, the provenance (prescribed or unprescribed by doctor), the storage period and also observe drug condition. This study was further analysis of subset data in block IV of Riskesdas 2013 in households. The data were classified by its mechanism and its structure. The result showed that East Java was the highest user of AINS drugs was (15%). Non selectif COX-2 drug and partial selectif COX-2 was 38,3% bought from drug store and 14,4% from drug store. For rheumatism treatment was all used for more than a month. Widely use of NSAIDs as a pain relief indicated the necessity of a proper medicine use information to avoid side effect of NSAID drug.
Uji Daya Antelmetika Ekstrak n-Heksan Rimpang Bangle (Zingiber cassumunar) pada Cacing Ascaris suum secara In Vitro Soleha, Maratu; Purba, Anny Victor
Jurnal Kefarmasian Indonesia VOLUME 3, NOMOR 1, FEBRUARI 2013
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

The objective of this research was to investigate the anthelmentics activities of Zingiber cassumunar rhizome n-hexane extract against Ascaris suum in-vitro. The experiments were carried out by using immersion method. The worm were soaked in extract of Zingiber cassumunar rhizome . One hundred and forty four ascaris worms were divided into 8 groups; each Petri contain 6 wors of Ascaris suum the dosage in every Petridish was 1 x LD50 (15,78 mg/100 ml), 2 x LD50 (31,56 mg/100 ml), 4 x LD50 (63,12 mg/100 ml), 8 x LD50 (126,24 mg/100 ml) and 12 x LD50 (189,36 mg/100 ml). The positive control used was pirantel pamoat 250 mg/100 ml and as negative controls were solutions like intestine and carboxy methyl cellulose 0,94% suspension. Experiment result shows that dosage 5 (189,36 mg/100 ml) was the most optimum dosage for anthelmentics treatment in that dosage 27,8% Ascaris suum were dead. Anthelmentics investigation was done by counting the deaths of Ascaris suum which were emmersed for 24 hours. The infusion of zingiber cassumunar has strongest activity as anthelmentics rather than in alcohol and n-hexane extract forms.
Co-Authors Ani Isnawati Anny Victor Purba AULIA RACHMA, FARADIVA Efrilia, Mega ika agustina Nyoman Fitri Rosa Adelina Soblia, Hamim Tsalis SYAHPUTRA, GURITNO Winarsih Winarsih