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All Journal Jurnal Ilmiah Manuntung Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Riset Kefarmasian Indonesia Jurnal Insan Farmasi Indonesia Jurnal Komunitas Farmasi Nasional
Efrilia, Mega
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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GAMBARAN INTERAKSI OBAT HIPOGLIKEMIK ORAL (OHO) DENGAN OBAT LAIN PADA PASIEN DIABETES MELITUS (DM) TIPE II DI APOTEK IMPHI PERIODE OKTOBER 2014 SAMPAI MARET 2015 Meryta, Aries; Efrilia, Mega; Chandra, Pra Panca Bayu
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.306 KB) | DOI: 10.51352/jim.v1i2.35

Abstract

Increasing complications of diabetes mellitus (DM) have tendency to amount of drug use, which can increase the risk of drug interaction. Drug interaction is a situation arising of administrations more than one drug at the same time that effects each drug can be interfere each other and or both are mutually and or undesirable side effect may a rise which could potentially harm and or doesn’t give clinically significant effect. This research aims to determinate the potential interactions and mechanisms of drug interactions and impacts based on the severity of the effect of therapy in patients type II of diabetes mellitus (DM) at Imphi’s Pharmacy in the period October 2014 until March 2015. The research used descriptive evaluative and retrospective method based on recipe sheets. Data analysis have done by screening of drug interaction and using drug interaction from software lexicomp and drug interaction stockley. The results showed that there are 28 recipe sheets (16,37%) from 171 recipe sheets of 110 patients that potentially occur pharmacodynamic mechanism of drug interaction with as many as 36 events (64,29%) as well as the mechanisms of drug interaction based on the severity of the effect of moderate kind of therapy as much as 40 events
PERBANDINGAN UJI DAYA HAMBAT ANTARA EKSTRAK AKAR BELUNTAS DENGAN KULIT BUAH MAHKOTA DEWA TERHADAP PERTUMBUHAN BAKTERI E.COLI Agustina, Ika; Efrilia, Mega; Lisnawati, Nia
Jurnal Riset Kefarmasian Indonesia Vol 1 No 3 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.604 KB) | DOI: 10.33759/jrki.v1i3.31

Abstract

When this has been much studied extracts of herbs or traditional medicines, among other crops beluntas (Pluchea indica Less) and mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) As an antibacterial. Previous research has suggested that the rind of the gods crown and root beluntas known to have antibacterial activity, but please be more certain with the same methods and evaluation in testing the antibacterial activity of both plants against bacteria Escherichia coli. Are both these plants have a vigorous activity the same or different from one another. The method used to test the antibacterial activity is using the disc. The results showed beluntas root extract has inhibitory activity against Escherichia coli was higher than fruit skin extracts gods crown with a minimum concentration of 6%, while the fruit skin extracts crowns a new god looks at a concentration of 12%. Based on the paired t-test showed that there is a significant difference between the antibacterial activity of root extracts beluntas with fruit leather crown god.
FORMULASI SEDIAAN ROLL ON AROMATERAPI KOMBINASI MINYAK ATSIRI KRANGEAN (Litsea cubeba (Lour.) Pers.) DAN MINYAK ATSIRI LAVENDER (Lavandula angustifolia Miller) Chandra, Pra Panca Bayu; Efrilia, Mega; Handayani, Indri Astuti
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1947

Abstract

Krangean and Lavender are natural ingredients producing essential oils. The use of krangean and lavender in the community as perfume ingredients. Krangean essential oil and lavender essential oil contain 1.8 cineol which has potential as aromatherapy. The purpose of the formulation of the Roll on aromatherapy preparation is to determine whether variations in the combination of krangean essential oil and lavender essential oil can affect the test parameters ((organoleptic test, homogeneity test, pH test and favorability test or hedon
PENGARUH KONSENTRASI ETANOL TERHADAP RENDEMEN EKSTRAK DAUN JATI BELANDA (Guazuma ulmifolia) DAN DAUN SUKUN (Artocarpus altilis) Falestin , Senny Listy Kartika; Efrilia, Mega; Chandra, Pra Panca Bayu; Loimalitna, Pricillya Maria; Sabrina, Alifa
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2093

Abstract

Daun jati belanda dan daun sukun merupakan bahan alam yang digunakan sebagai obat. Kandungan metabolit sekunder ekstrak daun jati belanda dan daun sukun diyakini berperan dalam memberikan khasiat sebagai obat bahan alam. Ekstrak bahan alam dengan pelarut etanol dapat berpengaruh terhadap rendemen. Tujuan penelitian ini untuk mengetahui pengaruh variasi konsentrasi pelarut terhadap rendemen ekstrak daun jati belanda dan daun sukun. Penelitian ini meliputi determinasi, pengumpulan dan penyiapan simplisia, pembuatan simplisia, ekstrak dan penetapan rendemen ekstrak. Pada penelitian ini serbuk daun jati belanda dan daun sukun sebanyak 20 gram diekstraksi dengan konsentrasi pelarut yang berbeda yaitu etanol 70%, 90% dan 95% dengan metode maserasi. Replikasi dilakukan pada masing-masing pelarut sebanyak 3 kali. Data dianalisis menggunakan metode deskriptif dan diolah dengan perangkat Statistical Product and Service Solutions (SPSS) 26. Hasil penelitian rendemen tertinggi yang diperoleh ekstrak etanol 70% daun jati belanda (Guazuma ulmifolia) dengan rata-rata 2,79% ± 0,06 serta ekstrak etanol 90% daun sukun (Artocarpus altilis) dengan rata-rata 10,33% ± 0,33. Hasil uji two way anova, diperoleh hasil nilai sig=0.000 < 0.05 sehingga kelompok tanaman dan konsentrasi etanol terdapat perbedaan yang signifikan pada hasil rendemen ekstrak.
IDENTIFIKASI CEMARAN LOGAM BERAT DALAM EKSTRAK ETANOL 70% BUAH OKRA (Abelmoschus esculentus L.): IDENTIFIKASI CEMARAN LOGAM BERAT DALAM EKSTRAK ETANOL 70% BUAH OKRA (Abelmoschus esculentus L.) CHANDRA, PRA; Efrilia, Mega; Prayoga, Tria; Lisnawati, Nia
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 7 No. 1 (2024): Volume 7, No 1, Tahun 2024
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v7i1.54951

Abstract

Okra fruit (Abelmoschus esculentus L.) is a natural ingredient that can be developed as a raw material for natural-based medicines. The phytochemical compounds contained in okra fruit are flavonoids, alkaloids, saponins, tannins, triterpenoids, coumarins, phenolics, glycosides. steroids and alkaloids, α-cellulose, hemicellulose, lignin, components. Okra fruit with varying secondary metabolite content produces positive effects on the potential pharmacological activity of okra fruit. The potential pharmacological activity of okra fruit is as antidiabetic, hypolipidemic, antioxidant, antimicrobial, anticancer, wound healing, hepatoprotective, immunomodulatory, neuroprotective and gastroprotective in addition to cardioprotective activity. Extracts must meet extract quality parameters, one of which is non-specific parameters for heavy metal contamination. This research aims to determine the heavy metal contamination content of Lead (Pb), Cadnium (Cd) and Arsenic (As) contained in the 70% ethanol extract of okra fruit. The okra fruit extraction process was carried out by maceration with 70% ethanol solvent. Determination of heavy metal content using an atomic absorption spectrophotometer instrument. The research results showed that the 70% ethanol extract of okra fruit did not contain Lead (Pb), Cadnium (Cd) and Arsenic (As). Keywords: Okra fruit, Abelmoschus esculentus, Heavy Metal Contamination
Aktivitas Aktivitas Antibakteri Ekstrak Etanol 96% Pada Daun Tua Medang Pirawas (Litsea elliptica Blume) Terhadap Bakteri Staphylococcus aureus: Aktivitas Antibakteri Ekstrak Etanol 96% Pada Daun Tua Medang Pirawas (Litsea elliptica Blume) Terhadap Bakteri Staphylococcus aureus SOLEHA, MARATU; AULIA RACHMA, FARADIVA; AGUSTINA, IKA; EFRILIA, MEGA; SYAHPUTRA, GURITNO
Jurnal Komunitas Farmasi Nasional Vol. 4 No. 1 (2024): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Litsea elliptica Blume, is one type of traditional medicinal plant that is widely used by the Indonesian people. This symplisia can be used to treat headaches, fever, stomach ulcers, and also as an insect repellent. Litsea elliptica Blume also has antimicrobial and antioxidant properties. Objective: This study aims to determine whether 96% ethanol extract of Litsea elliptica Blume leaves has antibacterial activity against Staphylococcus aureus bacteria. Methods: This research is a laboratory experiment with descriptive quantitative method conducted in this study to test the antibacterial properties of 96% ethanol extract of Medang Pirawas (Litsea elliptica Blume) against Staphylococcus aureus bacteria. Results: The yield of the thick extract of Litsea elliptica Blume was 19.36 %, and the classes of secondary metabolite compounds found were phenols, flavonoids, saponins, tannins, alkaloids, and terpenoids. The results of the antibacterial activity test of the viscous extract of Litsea elliptica Blume did not show antimicrobial properties against the growth of Staphylococcus aureus, which was characterized by not forming a clear zone on the media. Conclusion: From these results it can be concluded that there is no antibacterial activity of ethanol extract of medang pirawas (Litsea elliptica Blume) leaves against the growth of Staphylococcus aureus bacteria.
UJI MUTU SIMPLISIA DAN EKSTRAK ETANOL 96% RIMPANG JAHE (Zingiber officinale Roscoe) Efrilia, Mega; Chandra, Pra Panca Bayu; Endrawati, Santi
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 1 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i1.6817

Abstract

Ginger (Zingiber officinale Roscoe) has long been commonly consumed as a spice and traditional medicine. The aim of the research was to test the quality of simplicia and ginger rhizome extract. The testing procedure consists of preliminary quality testing, testing specific and non-specific parameters. Fresh ginger rhizomes are processed to become simplicia powder. The simplicia was extracted using the maceration method using 96% ethanol solvent, then concentrated until a thick extract was obtained. Simplicia and extracts are subjected to quality testing. The results showed that the level of foreign organic matter of simplicia was 1.34%, the fine degree of simplicia was 4/18 through mesh sieve number 4 100% and number 18 was 96%. Identity of the research sample Zingiber officinale Roscoe. The levels of compounds in simplicia that are soluble in water and ethanol are 16.86 ± 0.45% and 6.81 ± 0.23%. The levels of compounds in the extract that were soluble in water and ethanol were 13.55 ± 0.21% and 13.72 ± 0.16%. Drying loss of simplicia is 0.80 ± 0.52% and extract is 9.53 ± 0.25%. The water content for simplicia is 9.03 ± 0.64% and extract is 12.33 ± 1.53%. The specific gravity of the simplicia is 0.7849 ± 0.06 g/mL and the extract is 0.85 ± 0.09 g/mL. The total ash content of simplicia was 4.09 ± 0.97% and the extract was 3.63 ± 0.44%. The water-soluble ash content in simplicia is 2.17 ± 0.31% and the extract is 2.6 ± 0.26%. The insoluble ash content of simplicia acid was 1.11 ± 0.32% and the extract was 0.5 ± 0.46%. Testing the quality of simplicia and ginger rhizome extract met the requirements, namely all specific parameters as well as non-specific parameters (drying loss, total ash and acid insoluble ash).
Co-Authors AULIA RACHMA, FARADIVA CHANDRA, PRA Chandra, Pra Panca Bayu Endrawati, Santi Falestin , Senny Listy Kartika Handayani, Indri Astuti ika agustina Lisnawati, Nia Loimalitna, Pricillya Maria Maratu Soleha Meryta, Aries Prayoga, Tria Sabrina, Alifa SYAHPUTRA, GURITNO